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The map label for this gene is radA [H]

Identifier: 110680425

GI number: 110680425

Start: 3112701

End: 3114062

Strand: Direct

Name: radA [H]

Synonym: RD1_3245

Alternate gene names: 110680425

Gene position: 3112701-3114062 (Clockwise)

Preceding gene: 110680424

Following gene: 110680426

Centisome position: 75.31

GC content: 64.02

Gene sequence:

>1362_bases
ATGGTCAAATCCCCCTCATTCTCCTGCTCTGCCTGCGGCAGCGTCACGACCAAATGGGCCGGGCGCTGTGAATCCTGCGG
CGAGTGGAACACGATTTCCGAGGACGCAGGCATCTCGAAAGGCCCGGCCAAATCGCTTGGCGGCAAGCGCGGCGCATCGG
TCAAACTCACCAGCCTGTCCACCGAGGAAGCCCCCCCGCCCCGCACCACCTGCGGCATCAAGGAGTTGGACCGCGTCCTG
GGCGGCGGATTGGTTGCGGCTTCGGCGATCCTCGTGGGCGGGGACCCCGGCATCGGGAAATCCACGTTGCTGCTGCAAGC
CGCAGCCCAGTTCGCGCGCAGTGGCTTGAAAACAATATATGTTTCTGGCGAAGAGGCCTCTGCACAGGTGCGGATGCGCG
CGCAGCGTCTGGGATTGACCGACGCGCCGGTGCAACTCGCCGCAGAAACCAACCTGCGCGACATTCTCACCACGCTTGAG
GCGGAAAAGCCCCAGCTTGCCATCATCGATTCCATCCAGACCATGTGGGCTGACAATGTGGACAGCGCCCCGGGCTCGGT
CAGTCAGGTGCGCGCCGCAGCCCATGAGTTGACCAGTTTTGCCAAGCGCAAGGGGATCAGCGTGATCCTCGTGGGCCATG
TCACCAAGGAGGGCCAGATCGCAGGCCCCCGCGTCGTTGAACATATGGTCGACACAGTGCTCTATTTCGAGGGCGAGCGC
GGGCATCAGTTCCGCATCCTGCGCGCCGTCAAAAACCGCTTCGGTCCGGCAGACGAGATAGGCGTGTTCGAGATGACGGG
CAGCGGGCTGGACGAAGTGGCCAACCCTTCGGCGCTGTTCCTGAGTGAACGGGGGACGCCCTCACCCGGTTCGGTGGTGT
TTGCCGGGGTTGAGGGCACGCGCCCCGTCCTTGTCGAGTTTCAGGCGCTGGTGTCCCCCTCGCCCCATGCGCAGGCGCGC
CGCACTGTGGTCGGCTGGGACGGGGGACGCCTGGCGATGATCCTTGCCGTGCTGGAGGCGCGTTGCGGCATCCCCTTTGC
GGGGCTTGACGTCTATCTGAACGTGGCGGGCGGCATGAAAGTGTCAGAACCGGCAGCGGACCTCGCGGTGGCGGCGGCCC
TGCTCAGCGCGCGAGAGGACGCCGCATTGCCTGCGGATACGGTGGTTTTTGGCGAAATCAGCCTGTCTGGCGCCCTGCGC
CCGGCCACCCAGACCGAAAACAGGTTGAAAGAAGCGCAAAAACTTGGTTTTACCAGCGCCATTGCTGCCAAGGGCGGTAA
AGCGGTCGGGGTCAGCGGCATTACTTTGAACACGATGCCGGACCTGACGGGCTTTGTAGGCGAGATTTTTGGCGCAGGCT
AA

Upstream 100 bases:

>100_bases
GAAATCCGGGGCCTGTTTTGCGGCGCCAGCGCGACAGTCGCACAGAACCATCGACCCAAAATCTCTTTGACGGCAATCCT
CGTCTGCGCCACAAGAGGCC

Downstream 100 bases:

>100_bases
GCGTCGCGTAAAGAGGCAGTTGAGGCTATGGAAAACTTCACAATGATCGACGGGGTCGTGGCCCTTGTGATCGTCATTTC
GGCACTGCTTGCCTATAGTC

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MVKSPSFSCSACGSVTTKWAGRCESCGEWNTISEDAGISKGPAKSLGGKRGASVKLTSLSTEEAPPPRTTCGIKELDRVL
GGGLVAASAILVGGDPGIGKSTLLLQAAAQFARSGLKTIYVSGEEASAQVRMRAQRLGLTDAPVQLAAETNLRDILTTLE
AEKPQLAIIDSIQTMWADNVDSAPGSVSQVRAAAHELTSFAKRKGISVILVGHVTKEGQIAGPRVVEHMVDTVLYFEGER
GHQFRILRAVKNRFGPADEIGVFEMTGSGLDEVANPSALFLSERGTPSPGSVVFAGVEGTRPVLVEFQALVSPSPHAQAR
RTVVGWDGGRLAMILAVLEARCGIPFAGLDVYLNVAGGMKVSEPAADLAVAAALLSAREDAALPADTVVFGEISLSGALR
PATQTENRLKEAQKLGFTSAIAAKGGKAVGVSGITLNTMPDLTGFVGEIFGAG

Sequences:

>Translated_453_residues
MVKSPSFSCSACGSVTTKWAGRCESCGEWNTISEDAGISKGPAKSLGGKRGASVKLTSLSTEEAPPPRTTCGIKELDRVL
GGGLVAASAILVGGDPGIGKSTLLLQAAAQFARSGLKTIYVSGEEASAQVRMRAQRLGLTDAPVQLAAETNLRDILTTLE
AEKPQLAIIDSIQTMWADNVDSAPGSVSQVRAAAHELTSFAKRKGISVILVGHVTKEGQIAGPRVVEHMVDTVLYFEGER
GHQFRILRAVKNRFGPADEIGVFEMTGSGLDEVANPSALFLSERGTPSPGSVVFAGVEGTRPVLVEFQALVSPSPHAQAR
RTVVGWDGGRLAMILAVLEARCGIPFAGLDVYLNVAGGMKVSEPAADLAVAAALLSAREDAALPADTVVFGEISLSGALR
PATQTENRLKEAQKLGFTSAIAAKGGKAVGVSGITLNTMPDLTGFVGEIFGAG
>Mature_453_residues
MVKSPSFSCSACGSVTTKWAGRCESCGEWNTISEDAGISKGPAKSLGGKRGASVKLTSLSTEEAPPPRTTCGIKELDRVL
GGGLVAASAILVGGDPGIGKSTLLLQAAAQFARSGLKTIYVSGEEASAQVRMRAQRLGLTDAPVQLAAETNLRDILTTLE
AEKPQLAIIDSIQTMWADNVDSAPGSVSQVRAAAHELTSFAKRKGISVILVGHVTKEGQIAGPRVVEHMVDTVLYFEGER
GHQFRILRAVKNRFGPADEIGVFEMTGSGLDEVANPSALFLSERGTPSPGSVVFAGVEGTRPVLVEFQALVSPSPHAQAR
RTVVGWDGGRLAMILAVLEARCGIPFAGLDVYLNVAGGMKVSEPAADLAVAAALLSAREDAALPADTVVFGEISLSGALR
PATQTENRLKEAQKLGFTSAIAAKGGKAVGVSGITLNTMPDLTGFVGEIFGAG

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=432, Percent_Identity=47.9166666666667, Blast_Score=387, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR020588
- InterPro:   IPR004504
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC [H]

EC number: NA

Molecular weight: Translated: 46919; Mature: 46919

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKSPSFSCSACGSVTTKWAGRCESCGEWNTISEDAGISKGPAKSLGGKRGASVKLTSLS
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEEECC
TEEAPPPRTTCGIKELDRVLGGGLVAASAILVGGDPGIGKSTLLLQAAAQFARSGLKTIY
CCCCCCCCCCCCHHHHHHHHCCHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEE
VSGEEASAQVRMRAQRLGLTDAPVQLAAETNLRDILTTLEAEKPQLAIIDSIQTMWADNV
ECCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHCCCCCEEHHHHHHHHHCCCC
DSAPGSVSQVRAAAHELTSFAKRKGISVILVGHVTKEGQIAGPRVVEHMVDTVLYFEGER
CCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHEEEECCC
GHQFRILRAVKNRFGPADEIGVFEMTGSGLDEVANPSALFLSERGTPSPGSVVFAGVEGT
CCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHCCCCEEEEECCCCCCCCCEEEEECCCC
RPVLVEFQALVSPSPHAQARRTVVGWDGGRLAMILAVLEARCGIPFAGLDVYLNVAGGMK
CCCEEEHHHHCCCCCCHHHCCEEEECCCCHHHHHHHHHHHHCCCCEECCEEEEEECCCCC
VSEPAADLAVAAALLSAREDAALPADTVVFGEISLSGALRPATQTENRLKEAQKLGFTSA
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCHHH
IAAKGGKAVGVSGITLNTMPDLTGFVGEIFGAG
HHHCCCCEEEECCEEECCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MVKSPSFSCSACGSVTTKWAGRCESCGEWNTISEDAGISKGPAKSLGGKRGASVKLTSLS
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEEECC
TEEAPPPRTTCGIKELDRVLGGGLVAASAILVGGDPGIGKSTLLLQAAAQFARSGLKTIY
CCCCCCCCCCCCHHHHHHHHCCHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEE
VSGEEASAQVRMRAQRLGLTDAPVQLAAETNLRDILTTLEAEKPQLAIIDSIQTMWADNV
ECCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHCCCCCEEHHHHHHHHHCCCC
DSAPGSVSQVRAAAHELTSFAKRKGISVILVGHVTKEGQIAGPRVVEHMVDTVLYFEGER
CCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHEEEECCC
GHQFRILRAVKNRFGPADEIGVFEMTGSGLDEVANPSALFLSERGTPSPGSVVFAGVEGT
CCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHCCCCEEEEECCCCCCCCCEEEEECCCC
RPVLVEFQALVSPSPHAQARRTVVGWDGGRLAMILAVLEARCGIPFAGLDVYLNVAGGMK
CCCEEEHHHHCCCCCCHHHCCEEEECCCCHHHHHHHHHHHHCCCCEECCEEEEEECCCCC
VSEPAADLAVAAALLSAREDAALPADTVVFGEISLSGALRPATQTENRLKEAQKLGFTSA
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCHHH
IAAKGGKAVGVSGITLNTMPDLTGFVGEIFGAG
HHHCCCCEEEECCEEECCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA