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The map label for this gene is moaA [H]

Identifier: 110680396

GI number: 110680396

Start: 3079737

End: 3080909

Strand: Direct

Name: moaA [H]

Synonym: RD1_3215

Alternate gene names: 110680396

Gene position: 3079737-3080909 (Clockwise)

Preceding gene: 110680395

Following gene: 110680397

Centisome position: 74.51

GC content: 64.88

Gene sequence:

>1173_bases
ATGATCTCTGTCGCTGAGGCGCTGGCGCAGCTGTTTGCGCTGGTGGAAGAGGTTGACAGCGAGATCGTACCGCTGCGCAA
TGCCGCTGGCAGGGTGCTGGCCAGGGACGCCGTCGCGGCGCGCACGCAACCGCCGTTTGCCGCCTCCGCCATGGATGGTT
ATGCCCTGCGCGCCAGCGAAGTCGAACCGGACGCCATGTTCAAGGTCATCGGCGAGGCTGCGGCAGGTCATGCGTTTGAT
GGCCCTGTCGGACCCGGCCAATGCACGCGCATTTTCACCGGCGCGCCCGTTCCCGAGGGGGCGGATCAGGTGGTGCTGCA
AGAGGATGTCACCCGGCGCGGCGATCTGATCACGCTGGGCCACAGGGTGGAGGCGAAATCGAACATCCGACCGGCGGGGG
GTGATTTTAAAGCCGGCGACACGCTGAAGGCGCCGCGCGTTCTGTCCCCGTCTGATATTGCGCTTTTGGCTTCGATGAAC
ATCGCCGAGGTGCCGGTCGCGCGCGCGCCCACGGTCGCGATTGTTGCAACGGGCGATGAGCTGGTCGCCCCCGGCGAAGA
CCCCGGACCGGATCAGATCATCGCCTCCAACAGCTACGGGCTGGCGGCTTTGCTGGAAAAACACGGCGCACACTGCCGCC
TGTTGCCCATCGCACGCGACACCGAAGAGAGCCTGACCGCGGTGCTTGAACTGGCGTCAACGGCCGATCTTATCATCACC
ATTGGCGGTGCCTCTGTCGGCGATCATGATCTGGTGGCGCCGGTGGCCGAGAAAATGGGAATGGAGCGCGCGTTCTACAA
AGTGGCAATGCGCCCCGGCAAACCCCTTATGGCGGGGCGGCTTGGGACGTCGGCCCTCGTTGGCTTGCCCGGAAACCCTG
TATCTGCAATGGTTTGCGGGACGATCTTTGTTGTGCCCCTGCTGCGCGCCATGCTCGGGTTGGGACGGGCGGCGGCAACG
CGCGGTCAGCTGCCGCTCGCCCAAGCCCTACCGTCCAACGGGCCGCGCGAACACTACATGCGCGCATGTCGGACGGCGGA
AGGGCTGGTCGCCTTTGATCGTCAGGACAGCTCCTTGTTAAGCATCCTGTCGAACGCGGACGCCTTGCTCGTCAGACCGC
CGCACGCGCCCGCGGCACCAATCGGGACTCTGGTCGATTACATTGATCTGTAA

Upstream 100 bases:

>100_bases
CCGTCTATGACATGTGCAAGGCCGTCGACAAGGGGATGGAGGTCGGTGGCTTGCATGTCGTTTTGAAAGATGGCGGCAAA
TCCGGCCGGTACGAAGCGCC

Downstream 100 bases:

>100_bases
AGGTTTTGTTGACACAAAACAGGAACATGAATAGAACAAAAGCACATCAGGCCTCGGAGGACCAAAAAGATGCTCACCAA
GAAGCAGTTGGATTTGCTGG

Product: molybdenum cofactor biosynthesis protein A, putative

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MISVAEALAQLFALVEEVDSEIVPLRNAAGRVLARDAVAARTQPPFAASAMDGYALRASEVEPDAMFKVIGEAAAGHAFD
GPVGPGQCTRIFTGAPVPEGADQVVLQEDVTRRGDLITLGHRVEAKSNIRPAGGDFKAGDTLKAPRVLSPSDIALLASMN
IAEVPVARAPTVAIVATGDELVAPGEDPGPDQIIASNSYGLAALLEKHGAHCRLLPIARDTEESLTAVLELASTADLIIT
IGGASVGDHDLVAPVAEKMGMERAFYKVAMRPGKPLMAGRLGTSALVGLPGNPVSAMVCGTIFVVPLLRAMLGLGRAAAT
RGQLPLAQALPSNGPREHYMRACRTAEGLVAFDRQDSSLLSILSNADALLVRPPHAPAAPIGTLVDYIDL

Sequences:

>Translated_390_residues
MISVAEALAQLFALVEEVDSEIVPLRNAAGRVLARDAVAARTQPPFAASAMDGYALRASEVEPDAMFKVIGEAAAGHAFD
GPVGPGQCTRIFTGAPVPEGADQVVLQEDVTRRGDLITLGHRVEAKSNIRPAGGDFKAGDTLKAPRVLSPSDIALLASMN
IAEVPVARAPTVAIVATGDELVAPGEDPGPDQIIASNSYGLAALLEKHGAHCRLLPIARDTEESLTAVLELASTADLIIT
IGGASVGDHDLVAPVAEKMGMERAFYKVAMRPGKPLMAGRLGTSALVGLPGNPVSAMVCGTIFVVPLLRAMLGLGRAAAT
RGQLPLAQALPSNGPREHYMRACRTAEGLVAFDRQDSSLLSILSNADALLVRPPHAPAAPIGTLVDYIDL
>Mature_390_residues
MISVAEALAQLFALVEEVDSEIVPLRNAAGRVLARDAVAARTQPPFAASAMDGYALRASEVEPDAMFKVIGEAAAGHAFD
GPVGPGQCTRIFTGAPVPEGADQVVLQEDVTRRGDLITLGHRVEAKSNIRPAGGDFKAGDTLKAPRVLSPSDIALLASMN
IAEVPVARAPTVAIVATGDELVAPGEDPGPDQIIASNSYGLAALLEKHGAHCRLLPIARDTEESLTAVLELASTADLIIT
IGGASVGDHDLVAPVAEKMGMERAFYKVAMRPGKPLMAGRLGTSALVGLPGNPVSAMVCGTIFVVPLLRAMLGLGRAAAT
RGQLPLAQALPSNGPREHYMRACRTAEGLVAFDRQDSSLLSILSNADALLVRPPHAPAAPIGTLVDYIDL

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=397, Percent_Identity=36.272040302267, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI66932975, Length=397, Percent_Identity=36.272040302267, Blast_Score=184, Evalue=1e-46,
Organism=Escherichia coli, GI1787049, Length=380, Percent_Identity=36.0526315789474, Blast_Score=200, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI25147659, Length=353, Percent_Identity=31.4447592067989, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17562606, Length=324, Percent_Identity=26.2345679012346, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17136978, Length=332, Percent_Identity=31.6265060240964, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24638841, Length=332, Percent_Identity=31.6265060240964, Blast_Score=137, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 40422; Mature: 40422

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVAEALAQLFALVEEVDSEIVPLRNAAGRVLARDAVAARTQPPFAASAMDGYALRASE
CCCHHHHHHHHHHHHHHHCCHHCCCHHHCCHHHHHHHHHHCCCCCCCHHCCCCCEEECCC
VEPDAMFKVIGEAAAGHAFDGPVGPGQCTRIFTGAPVPEGADQVVLQEDVTRRGDLITLG
CCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEC
HRVEAKSNIRPAGGDFKAGDTLKAPRVLSPSDIALLASMNIAEVPVARAPTVAIVATGDE
CEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHCCCCCCCEEEEEECCCC
LVAPGEDPGPDQIIASNSYGLAALLEKHGAHCRLLPIARDTEESLTAVLELASTADLIIT
EECCCCCCCCCCEEECCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEE
IGGASVGDHDLVAPVAEKMGMERAFYKVAMRPGKPLMAGRLGTSALVGLPGNPVSAMVCG
ECCCCCCCCHHHHHHHHHHCHHHHHHHHHCCCCCCCHHCCCCCCEEEECCCCCHHHHHHH
TIFVVPLLRAMLGLGRAAATRGQLPLAQALPSNGPREHYMRACRTAEGLVAFDRQDSSLL
HHHHHHHHHHHHCCCHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCEEECCCCHHHH
SILSNADALLVRPPHAPAAPIGTLVDYIDL
HHHCCCCEEEEECCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MISVAEALAQLFALVEEVDSEIVPLRNAAGRVLARDAVAARTQPPFAASAMDGYALRASE
CCCHHHHHHHHHHHHHHHCCHHCCCHHHCCHHHHHHHHHHCCCCCCCHHCCCCCEEECCC
VEPDAMFKVIGEAAAGHAFDGPVGPGQCTRIFTGAPVPEGADQVVLQEDVTRRGDLITLG
CCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEC
HRVEAKSNIRPAGGDFKAGDTLKAPRVLSPSDIALLASMNIAEVPVARAPTVAIVATGDE
CEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHCCCCCCCEEEEEECCCC
LVAPGEDPGPDQIIASNSYGLAALLEKHGAHCRLLPIARDTEESLTAVLELASTADLIIT
EECCCCCCCCCCEEECCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEE
IGGASVGDHDLVAPVAEKMGMERAFYKVAMRPGKPLMAGRLGTSALVGLPGNPVSAMVCG
ECCCCCCCCHHHHHHHHHHCHHHHHHHHHCCCCCCCHHCCCCCCEEEECCCCCHHHHHHH
TIFVVPLLRAMLGLGRAAATRGQLPLAQALPSNGPREHYMRACRTAEGLVAFDRQDSSLL
HHHHHHHHHHHHCCCHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCEEECCCCHHHH
SILSNADALLVRPPHAPAAPIGTLVDYIDL
HHHCCCCEEEEECCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3045084; 8905232; 9278503; 9515915 [H]