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The map label for this gene is moaC [H]

Identifier: 110680395

GI number: 110680395

Start: 3079261

End: 3079740

Strand: Direct

Name: moaC [H]

Synonym: RD1_3214

Alternate gene names: 110680395

Gene position: 3079261-3079740 (Clockwise)

Preceding gene: 110680394

Following gene: 110680396

Centisome position: 74.5

GC content: 60.21

Gene sequence:

>480_bases
GTGAGCGGCAAGCTGACCCATTTTGATGGCAAGGGCGATGCCCAGATGGTGAATGTGGGGGACAAAGCGATCACGGACCG
GATCGCGGTGGCCACATGCTTCATCAGGATGAAACCCGAAACCCATGAAATCATTACGCACGGCCGCGCGAAAAAGGGTG
ATGTGCTTGGTGTGGCGCGGCTGGCAGGGATCATGGCGGCTAAGCGCACGTCCGATCTGATCCCGCTGTGTCATCCGCTG
CCGATCACCAAGGTCGCCGTGGAACTTACGCCTGATGCGCAATTGCCCGGCGTGCGGATTGAGGCCACGGTCAAGACAAC
GGGCCAGACCGGTGTCGAGATGGAGGCGCTGACAGCGGCCAATATCGCCGCCCTCACCGTCTATGACATGTGCAAGGCCG
TCGACAAGGGGATGGAGGTCGGTGGCTTGCATGTCGTTTTGAAAGATGGCGGCAAATCCGGCCGGTACGAAGCGCCATGA

Upstream 100 bases:

>100_bases
CGTATCTTCCTGATCGGGGAAAGCCTGATGCGGCAGGATGATGTGACGCTGGCCACGAAAAAGCTGCTTGAGAAACCTGC
CATGGCGGGGGGGATGTAGC

Downstream 100 bases:

>100_bases
TCTCTGTCGCTGAGGCGCTGGCGCAGCTGTTTGCGCTGGTGGAAGAGGTTGACAGCGAGATCGTACCGCTGCGCAATGCC
GCTGGCAGGGTGCTGGCCAG

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MSGKLTHFDGKGDAQMVNVGDKAITDRIAVATCFIRMKPETHEIITHGRAKKGDVLGVARLAGIMAAKRTSDLIPLCHPL
PITKVAVELTPDAQLPGVRIEATVKTTGQTGVEMEALTAANIAALTVYDMCKAVDKGMEVGGLHVVLKDGGKSGRYEAP

Sequences:

>Translated_159_residues
MSGKLTHFDGKGDAQMVNVGDKAITDRIAVATCFIRMKPETHEIITHGRAKKGDVLGVARLAGIMAAKRTSDLIPLCHPL
PITKVAVELTPDAQLPGVRIEATVKTTGQTGVEMEALTAANIAALTVYDMCKAVDKGMEVGGLHVVLKDGGKSGRYEAP
>Mature_158_residues
SGKLTHFDGKGDAQMVNVGDKAITDRIAVATCFIRMKPETHEIITHGRAKKGDVLGVARLAGIMAAKRTSDLIPLCHPLP
ITKVAVELTPDAQLPGVRIEATVKTTGQTGVEMEALTAANIAALTVYDMCKAVDKGMEVGGLHVVLKDGGKSGRYEAP

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=155, Percent_Identity=54.8387096774194, Blast_Score=165, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=44.2953020134228, Blast_Score=126, Evalue=5e-30,
Organism=Drosophila melanogaster, GI28574490, Length=150, Percent_Identity=50.6666666666667, Blast_Score=146, Evalue=5e-36,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=49.6350364963504, Blast_Score=130, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 16762; Mature: 16631

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGKLTHFDGKGDAQMVNVGDKAITDRIAVATCFIRMKPETHEIITHGRAKKGDVLGVAR
CCCCEEEECCCCCEEEEECCCHHHHHHHEEEEEEEEECCCHHHHHHCCCCCCCCCHHHHH
LAGIMAAKRTSDLIPLCHPLPITKVAVELTPDAQLPGVRIEATVKTTGQTGVEMEALTAA
HHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCEEEHHHHH
NIAALTVYDMCKAVDKGMEVGGLHVVLKDGGKSGRYEAP
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SGKLTHFDGKGDAQMVNVGDKAITDRIAVATCFIRMKPETHEIITHGRAKKGDVLGVAR
CCCEEEECCCCCEEEEECCCHHHHHHHEEEEEEEEECCCHHHHHHCCCCCCCCCHHHHH
LAGIMAAKRTSDLIPLCHPLPITKVAVELTPDAQLPGVRIEATVKTTGQTGVEMEALTAA
HHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCEEEHHHHH
NIAALTVYDMCKAVDKGMEVGGLHVVLKDGGKSGRYEAP
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA