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The map label for this gene is ung [H]

Identifier: 110680393

GI number: 110680393

Start: 3077794

End: 3078450

Strand: Direct

Name: ung [H]

Synonym: RD1_3211

Alternate gene names: 110680393

Gene position: 3077794-3078450 (Clockwise)

Preceding gene: 110680392

Following gene: 110680394

Centisome position: 74.47

GC content: 65.45

Gene sequence:

>657_bases
GTGCCTGCGCTCGGTGGTTGGCACGCGCTGCCGTTTTTCGCGAAAACCTGGCCGGGCATCAGTGACGTCCTGGCGCGCGA
AATAGCGCCGGTCCTGCCGCCCCGGGAGGAGATTTTCGCCGCCCTTGAGCGCACACAACCCCAGCATACGCGCGTCGTGA
TCCTCGGTCAGGACCCCTATCCGACCCCCGGTCACGCCCATGGGTTTGCCTTTTCCGCCGCAGCACAAACGCGGCCCCTG
CCCCGGTCATTGTCCAACATCTTCAAGGAGATGGATGCGGACCTTGGTGCTGCGCCGCGCCATGCGGATCTGCGGTTTTG
GGCGGATCAGGGTGTGCTGTTGCTCAACACGGCCCTGACGGTGCGCGCCCATGAGGCCGGATCGCACGCGAAACTCGGAT
GGCATGCGCTGACGCAACAGGTGCTGGCACATCTTGACGACCATCCGCGCGCCTTTTTGTTGTGGGGGGCGCATGCGCAA
AAGGCGGCGCGCGACGTCGACCCCATCCGGCATCTGAAGATTGAAACCGCGCATCCCTCGCCGCTGTCGGCGCGGCGCGG
CTTTTTCGGCTCCCGCCCCTTCAGCCGGGTGAATGACTGGTTGCAGGCGCAGGGCCATCAGGCCATAAACTGGAGCAATC
CGCCGGAGGCCCCATGA

Upstream 100 bases:

>100_bases
CCCTGCAGGACGGTGTGGAAATGGCCGCCACATCCATCGACAGCGGCGCGGCGGCGCGTAAAATCGAGGCTGTTGCACAG
ATCACGCAAGCCACGTGAGG

Downstream 100 bases:

>100_bases
CACAGACGATCCTTGATAAAATCAAAGCCTACAAACTCGAAGAGATTGCCCGCGACAAAGCCGAAACGCCGCTTGAGGCG
GTGGAGGCCTTGGCGCGAGA

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MPALGGWHALPFFAKTWPGISDVLAREIAPVLPPREEIFAALERTQPQHTRVVILGQDPYPTPGHAHGFAFSAAAQTRPL
PRSLSNIFKEMDADLGAAPRHADLRFWADQGVLLLNTALTVRAHEAGSHAKLGWHALTQQVLAHLDDHPRAFLLWGAHAQ
KAARDVDPIRHLKIETAHPSPLSARRGFFGSRPFSRVNDWLQAQGHQAINWSNPPEAP

Sequences:

>Translated_218_residues
MPALGGWHALPFFAKTWPGISDVLAREIAPVLPPREEIFAALERTQPQHTRVVILGQDPYPTPGHAHGFAFSAAAQTRPL
PRSLSNIFKEMDADLGAAPRHADLRFWADQGVLLLNTALTVRAHEAGSHAKLGWHALTQQVLAHLDDHPRAFLLWGAHAQ
KAARDVDPIRHLKIETAHPSPLSARRGFFGSRPFSRVNDWLQAQGHQAINWSNPPEAP
>Mature_217_residues
PALGGWHALPFFAKTWPGISDVLAREIAPVLPPREEIFAALERTQPQHTRVVILGQDPYPTPGHAHGFAFSAAAQTRPLP
RSLSNIFKEMDADLGAAPRHADLRFWADQGVLLLNTALTVRAHEAGSHAKLGWHALTQQVLAHLDDHPRAFLLWGAHAQK
AARDVDPIRHLKIETAHPSPLSARRGFFGSRPFSRVNDWLQAQGHQAINWSNPPEAP

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=212, Percent_Identity=44.3396226415094, Blast_Score=170, Evalue=7e-43,
Organism=Homo sapiens, GI6224979, Length=214, Percent_Identity=43.9252336448598, Blast_Score=170, Evalue=1e-42,
Organism=Escherichia coli, GI1788934, Length=208, Percent_Identity=44.2307692307692, Blast_Score=166, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17556304, Length=188, Percent_Identity=43.0851063829787, Blast_Score=157, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6323620, Length=227, Percent_Identity=40.0881057268723, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 24070; Mature: 23938

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALGGWHALPFFAKTWPGISDVLAREIAPVLPPREEIFAALERTQPQHTRVVILGQDPY
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCCC
PTPGHAHGFAFSAAAQTRPLPRSLSNIFKEMDADLGAAPRHADLRFWADQGVLLLNTALT
CCCCCCCCEEEEHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEEEE
VRAHEAGSHAKLGWHALTQQVLAHLDDHPRAFLLWGAHAQKAARDVDPIRHLKIETAHPS
EEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHCCHHHHEEEECCCCC
PLSARRGFFGSRPFSRVNDWLQAQGHQAINWSNPPEAP
CCHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PALGGWHALPFFAKTWPGISDVLAREIAPVLPPREEIFAALERTQPQHTRVVILGQDPY
CCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCCC
PTPGHAHGFAFSAAAQTRPLPRSLSNIFKEMDADLGAAPRHADLRFWADQGVLLLNTALT
CCCCCCCCEEEEHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEEEE
VRAHEAGSHAKLGWHALTQQVLAHLDDHPRAFLLWGAHAQKAARDVDPIRHLKIETAHPS
EEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHCCHHHHEEEECCCCC
PLSARRGFFGSRPFSRVNDWLQAQGHQAINWSNPPEAP
CCHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA