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The map label for this gene is gpt

Identifier: 110680384

GI number: 110680384

Start: 3065612

End: 3066142

Strand: Direct

Name: gpt

Synonym: RD1_3201

Alternate gene names: 110680384

Gene position: 3065612-3066142 (Clockwise)

Preceding gene: 110680383

Following gene: 110680385

Centisome position: 74.17

GC content: 62.15

Gene sequence:

>531_bases
ATGAGTTCCAAAGACCAAAGCCGCCTGCCCCATGAAAAGGGGTTTCATATCAGTTGGGACCAGATCCACCGCGACAGCCG
TGCGCTCGCGTGGCGGCTGGACGGGCAAGGCCCTGATGAGGGCGCATGGCGGGCGGTTGTTGCGATCACGCGCGGCGGCA
TGGCCCCGGCGATGATCGTCGCGCGGGAGTTGGACATTCGCGTGGTCGATACGATTTCGGTGATGTCCTATCATTCGGGC
GGCGGCAAGGCGGACCAGCGCCGGGACGCAAAGGTGCTCAAGGCACCGGATGCGGACATGATGGGGGACGGGACGGGCAT
TCTGATCGTCGATGATCTGGTGGACAGCGGCAAGACGCTGGAACTGGTGCGCGCGCAATACCCCAATGCGCATTTCGCCA
CCGTCTATGCCAAGCCGCAGGGCGAGCCGCAGGTGAACACGTTCATCACCGGGGTCAGTCAGGACACGTGGATTTTCTTT
CCCTGGGATATGGCGCTGCAATATGTGGAACCCTATCGCGGCACGGATTGA

Upstream 100 bases:

>100_bases
CCCGTGCGGCCTATCTGCGCATCAAGTCCTGGGCGGATCGTATTGCCGCTGCTGTGATGGGCGCGCTTGGGCTGCGCCTG
CTTTTCGAAAGGTAACGAAC

Downstream 100 bases:

>100_bases
GATGAGGACGCGAAGCGCATGACTCCGACACGCACGCAAACAACCTTCATGCCCCCGGTGATGGAGGCGCGGCGCTGGCT
GGCTGGCGTGACCTTTGCGC

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MSSKDQSRLPHEKGFHISWDQIHRDSRALAWRLDGQGPDEGAWRAVVAITRGGMAPAMIVARELDIRVVDTISVMSYHSG
GGKADQRRDAKVLKAPDADMMGDGTGILIVDDLVDSGKTLELVRAQYPNAHFATVYAKPQGEPQVNTFITGVSQDTWIFF
PWDMALQYVEPYRGTD

Sequences:

>Translated_176_residues
MSSKDQSRLPHEKGFHISWDQIHRDSRALAWRLDGQGPDEGAWRAVVAITRGGMAPAMIVARELDIRVVDTISVMSYHSG
GGKADQRRDAKVLKAPDADMMGDGTGILIVDDLVDSGKTLELVRAQYPNAHFATVYAKPQGEPQVNTFITGVSQDTWIFF
PWDMALQYVEPYRGTD
>Mature_175_residues
SSKDQSRLPHEKGFHISWDQIHRDSRALAWRLDGQGPDEGAWRAVVAITRGGMAPAMIVARELDIRVVDTISVMSYHSGG
GKADQRRDAKVLKAPDADMMGDGTGILIVDDLVDSGKTLELVRAQYPNAHFATVYAKPQGEPQVNTFITGVSQDTWIFFP
WDMALQYVEPYRGTD

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily

Homologues:

Organism=Escherichia coli, GI1786433, Length=160, Percent_Identity=42.5, Blast_Score=134, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XGPT_ROSDO (Q163Y8)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_683391.1
- ProteinModelPortal:   Q163Y8
- SMR:   Q163Y8
- STRING:   Q163Y8
- GeneID:   4198591
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_3201
- NMPDR:   fig|375451.6.peg.2973
- eggNOG:   COG0503
- HOGENOM:   HBG503428
- OMA:   LVDTFIT
- PhylomeDB:   Q163Y8
- ProtClustDB:   PRK09177
- BioCyc:   RDEN375451:RD1_3201-MONOMER
- HAMAP:   MF_01903
- InterPro:   IPR000836

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 19531; Mature: 19400

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 88-88 BINDING 115-115 BINDING 158-158

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKDQSRLPHEKGFHISWDQIHRDSRALAWRLDGQGPDEGAWRAVVAITRGGMAPAMIV
CCCCCCCCCCCCCCCEEEHHHHCCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCEEEE
ARELDIRVVDTISVMSYHSGGGKADQRRDAKVLKAPDADMMGDGTGILIVDDLVDSGKTL
EEECCEEEEEEEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCEE
ELVRAQYPNAHFATVYAKPQGEPQVNTFITGVSQDTWIFFPWDMALQYVEPYRGTD
EEEECCCCCCEEEEEEECCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SSKDQSRLPHEKGFHISWDQIHRDSRALAWRLDGQGPDEGAWRAVVAITRGGMAPAMIV
CCCCCCCCCCCCCCEEEHHHHCCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCEEEE
ARELDIRVVDTISVMSYHSGGGKADQRRDAKVLKAPDADMMGDGTGILIVDDLVDSGKTL
EEECCEEEEEEEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCEE
ELVRAQYPNAHFATVYAKPQGEPQVNTFITGVSQDTWIFFPWDMALQYVEPYRGTD
EEEECCCCCCEEEEEEECCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA