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The map label for this gene is rhtC [H]

Identifier: 110680383

GI number: 110680383

Start: 3064992

End: 3065606

Strand: Direct

Name: rhtC [H]

Synonym: RD1_3200

Alternate gene names: 110680383

Gene position: 3064992-3065606 (Clockwise)

Preceding gene: 110680382

Following gene: 110680384

Centisome position: 74.16

GC content: 65.85

Gene sequence:

>615_bases
GTGAGCGATCTGTCCTGGGCCCAGCTTGCCGCTTTCAACGTCACCCTGTTGGTGGCGATGGCGGCACCGGGTCCGGCGTT
TCTGCTGGTGTTGCGCAACAGCATCGCGCAGGGGCGGCGCGCGGGGGTCATGACCGGTGTGGGTCTGGGTGTGATGGCCG
CGATCTGGACGGCGGCGGCGCTTGCCGGGCTGGCGGCCCTGTTTGACATGGTGCCCTGGGCCTATGCGACGATGAAGGCC
ATCGGCGCGCTTTACCTGATCTATCTGGCATGGGGCATGTGGCGCGGGGCGGCGCAGCCGCTCAAGGCGTCATCCGAACG
GGCCAGCCGGCGCGCCTTTCGCGCGGGGCTGCTGGTCAACCTGACCAATCCGAAATCCGTCCTCTTTGCCGGTGCCGTGA
TCGTTGTGATCTTTCCCGCGGGGCTGTCGCTGACGGACAGCGCGCTGATTGTGGCCAATCATCTGGTCGTGGAGCTATGC
GTCTATGCGGCCATGGCTTTCGGGTTGTCGACCGCCCCTGCCCGTGCGGCCTATCTGCGCATCAAGTCCTGGGCGGATCG
TATTGCCGCTGCTGTGATGGGCGCGCTTGGGCTGCGCCTGCTTTTCGAAAGGTAA

Upstream 100 bases:

>100_bases
GGTTCAGGCACCACGGGGGAGAACCTGCATGTGGATGCGGGGTATCATGTGGTGGGCATGAAGGCGGTGGACGCCCCCGA
CATGAGCAAGGAATAACGCA

Downstream 100 bases:

>100_bases
CGAACATGAGTTCCAAAGACCAAAGCCGCCTGCCCCATGAAAAGGGGTTTCATATCAGTTGGGACCAGATCCACCGCGAC
AGCCGTGCGCTCGCGTGGCG

Product: threonine efflux protein

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MSDLSWAQLAAFNVTLLVAMAAPGPAFLLVLRNSIAQGRRAGVMTGVGLGVMAAIWTAAALAGLAALFDMVPWAYATMKA
IGALYLIYLAWGMWRGAAQPLKASSERASRRAFRAGLLVNLTNPKSVLFAGAVIVVIFPAGLSLTDSALIVANHLVVELC
VYAAMAFGLSTAPARAAYLRIKSWADRIAAAVMGALGLRLLFER

Sequences:

>Translated_204_residues
MSDLSWAQLAAFNVTLLVAMAAPGPAFLLVLRNSIAQGRRAGVMTGVGLGVMAAIWTAAALAGLAALFDMVPWAYATMKA
IGALYLIYLAWGMWRGAAQPLKASSERASRRAFRAGLLVNLTNPKSVLFAGAVIVVIFPAGLSLTDSALIVANHLVVELC
VYAAMAFGLSTAPARAAYLRIKSWADRIAAAVMGALGLRLLFER
>Mature_203_residues
SDLSWAQLAAFNVTLLVAMAAPGPAFLLVLRNSIAQGRRAGVMTGVGLGVMAAIWTAAALAGLAALFDMVPWAYATMKAI
GALYLIYLAWGMWRGAAQPLKASSERASRRAFRAGLLVNLTNPKSVLFAGAVIVVIFPAGLSLTDSALIVANHLVVELCV
YAAMAFGLSTAPARAAYLRIKSWADRIAAAVMGALGLRLLFER

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=194, Percent_Identity=27.8350515463918, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786522, Length=215, Percent_Identity=30.2325581395349, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788099, Length=177, Percent_Identity=28.2485875706215, Blast_Score=68, Evalue=3e-13,
Organism=Escherichia coli, GI48994979, Length=162, Percent_Identity=32.7160493827161, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21451; Mature: 21320

Theoretical pI: Translated: 11.17; Mature: 11.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLSWAQLAAFNVTLLVAMAAPGPAFLLVLRNSIAQGRRAGVMTGVGLGVMAAIWTAAA
CCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHH
LAGLAALFDMVPWAYATMKAIGALYLIYLAWGMWRGAAQPLKASSERASRRAFRAGLLVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCEEEE
LTNPKSVLFAGAVIVVIFPAGLSLTDSALIVANHLVVELCVYAAMAFGLSTAPARAAYLR
ECCCHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
IKSWADRIAAAVMGALGLRLLFER
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDLSWAQLAAFNVTLLVAMAAPGPAFLLVLRNSIAQGRRAGVMTGVGLGVMAAIWTAAA
CCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHH
LAGLAALFDMVPWAYATMKAIGALYLIYLAWGMWRGAAQPLKASSERASRRAFRAGLLVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCEEEE
LTNPKSVLFAGAVIVVIFPAGLSLTDSALIVANHLVVELCVYAAMAFGLSTAPARAAYLR
ECCCHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
IKSWADRIAAAVMGALGLRLLFER
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]