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The map label for this gene is galM [H]

Identifier: 110680297

GI number: 110680297

Start: 2987282

End: 2988250

Strand: Direct

Name: galM [H]

Synonym: RD1_3109

Alternate gene names: 110680297

Gene position: 2987282-2988250 (Clockwise)

Preceding gene: 110680296

Following gene: 110680298

Centisome position: 72.28

GC content: 58.41

Gene sequence:

>969_bases
ATGATTTCGCTGCGCTCCGCATCGCTGACCGCTCAGATTCTGCCTTTTGGCGCGACCTTGGCAGGGCTTTGGCTTGACGG
GCATCCCGACAGCCTCGTGATCGGCTCATCCGATGCAGAGGCTTACACGGACCACCTGCGCTATTTTGGTGCCGTCATCG
GCCCGATTGCAAACCGGATTTCCGGTGCGGCGCTCCAGATTGGGGGCGCTGCGTTCAGTATGGAAGCGAATGAAGGCAGC
GCCTGCCTGCACAGCGGGGCCAGCGGGCTGCACGCACGCATGTGGACAGTCTTGCGGTGTTCAGCGGCGGCCGTCTCCTT
GCGATGCGAGTTGCCAGATGGCGCAAATGGGCTGCCCGGCAATCGGAGAGTTGAGGCACATTACGAGCTGACGGATGATG
GCCAGTTGGTGCTCGAACTGACGGCGCAAAGCGACCGCGCAACGGCCATCAATCTCGCGCATCACCCCTATTGGAACCTT
GGCAACGCAGACACCATACAGAACCACCATCTGATGGTTTACGCGGATACCTACCTGCCGGTCGACCAACAAATCCTGCC
GACAGGTGAAATCGCGCCTGTTGCGCAAACAGCCTATGATTTTCAAACCCTGCGGGCGATCCCAATCGACCGAACACTGG
ATGCGAACTTATGCCTTGCCAAAATACGGCGCGCGCGCCCCGAACCGGCTGCGCGCTTGCGCGGTCCGTCAGGTGTGACC
CTGCAAATCGACACCACGGAACCGGGACTGCAAATCTACAATGGCAGCAGTTTACACGATGTGCCTATTTCACTTCATGA
TCAACGTGTTCTGAGGCCCTTTTCAGGTATCGCATTAGAGCCGCAAGGCTGGCCTGACGCGCCACACAACCGCGCTTTTC
CCAGCATTGTTTTACGCCCGGGTCAGACATACCGGCAAAAAACGATCTATCGGATTTGGCACGAATTGAGCGAACCCGCC
ACATTCTGA

Upstream 100 bases:

>100_bases
TCAGGGCTGGATGCTCCGCTGAGGGTGCGGCGCATGCGGCGTGGTATCTGACGCGCGCAAGGTCTAGACTGCGTGCGAGA
TCGCACAAAGGGTTCGCCAC

Downstream 100 bases:

>100_bases
ACACGGAGATGACGCGTCACCGGCAAACCTGACGTTAAGCCTACACAGGTATCTTTATTGCGTTAACGATGGGAATCAGT
TTCATGCCAACCGAACCGAA

Product: aldose 1-epimerase, putative

Products: NA

Alternate protein names: Galactose mutarotase; Type-1 mutarotase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MISLRSASLTAQILPFGATLAGLWLDGHPDSLVIGSSDAEAYTDHLRYFGAVIGPIANRISGAALQIGGAAFSMEANEGS
ACLHSGASGLHARMWTVLRCSAAAVSLRCELPDGANGLPGNRRVEAHYELTDDGQLVLELTAQSDRATAINLAHHPYWNL
GNADTIQNHHLMVYADTYLPVDQQILPTGEIAPVAQTAYDFQTLRAIPIDRTLDANLCLAKIRRARPEPAARLRGPSGVT
LQIDTTEPGLQIYNGSSLHDVPISLHDQRVLRPFSGIALEPQGWPDAPHNRAFPSIVLRPGQTYRQKTIYRIWHELSEPA
TF

Sequences:

>Translated_322_residues
MISLRSASLTAQILPFGATLAGLWLDGHPDSLVIGSSDAEAYTDHLRYFGAVIGPIANRISGAALQIGGAAFSMEANEGS
ACLHSGASGLHARMWTVLRCSAAAVSLRCELPDGANGLPGNRRVEAHYELTDDGQLVLELTAQSDRATAINLAHHPYWNL
GNADTIQNHHLMVYADTYLPVDQQILPTGEIAPVAQTAYDFQTLRAIPIDRTLDANLCLAKIRRARPEPAARLRGPSGVT
LQIDTTEPGLQIYNGSSLHDVPISLHDQRVLRPFSGIALEPQGWPDAPHNRAFPSIVLRPGQTYRQKTIYRIWHELSEPA
TF
>Mature_322_residues
MISLRSASLTAQILPFGATLAGLWLDGHPDSLVIGSSDAEAYTDHLRYFGAVIGPIANRISGAALQIGGAAFSMEANEGS
ACLHSGASGLHARMWTVLRCSAAAVSLRCELPDGANGLPGNRRVEAHYELTDDGQLVLELTAQSDRATAINLAHHPYWNL
GNADTIQNHHLMVYADTYLPVDQQILPTGEIAPVAQTAYDFQTLRAIPIDRTLDANLCLAKIRRARPEPAARLRGPSGVT
LQIDTTEPGLQIYNGSSLHDVPISLHDQRVLRPFSGIALEPQGWPDAPHNRAFPSIVLRPGQTYRQKTIYRIWHELSEPA
TF

Specific function: Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose [H]

COG id: COG2017

COG function: function code G; Galactose mutarotase and related enzymes

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldose epimerase family [H]

Homologues:

Organism=Homo sapiens, GI20270355, Length=324, Percent_Identity=35.1851851851852, Blast_Score=185, Evalue=5e-47,
Organism=Escherichia coli, GI1786971, Length=335, Percent_Identity=28.955223880597, Blast_Score=146, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17557428, Length=318, Percent_Identity=32.3899371069182, Blast_Score=168, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI115533334, Length=318, Percent_Identity=32.3899371069182, Blast_Score=168, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6319493, Length=329, Percent_Identity=26.1398176291793, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6322004, Length=333, Percent_Identity=27.3273273273273, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324399, Length=332, Percent_Identity=25.9036144578313, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24659048, Length=331, Percent_Identity=29.607250755287, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24668282, Length=329, Percent_Identity=29.7872340425532, Blast_Score=144, Evalue=8e-35,
Organism=Drosophila melanogaster, GI24668278, Length=334, Percent_Identity=25.748502994012, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24583720, Length=334, Percent_Identity=25.1497005988024, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24641876, Length=345, Percent_Identity=23.768115942029, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018052
- InterPro:   IPR008183
- InterPro:   IPR015443
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.3 [H]

Molecular weight: Translated: 34959; Mature: 34959

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISLRSASLTAQILPFGATLAGLWLDGHPDSLVIGSSDAEAYTDHLRYFGAVIGPIANRI
CCEECCCCCEEEEEECCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHC
SGAALQIGGAAFSMEANEGSACLHSGASGLHARMWTVLRCSAAAVSLRCELPDGANGLPG
CCCEEEECCEEEEEECCCCCHHHHCCCCCHHHHHHHHHHHCCEEEEEEEECCCCCCCCCC
NRRVEAHYELTDDGQLVLELTAQSDRATAINLAHHPYWNLGNADTIQNHHLMVYADTYLP
CCEEEEEEEECCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCEECCCEEEEEEECCCC
VDQQILPTGEIAPVAQTAYDFQTLRAIPIDRTLDANLCLAKIRRARPEPAARLRGPSGVT
CCCCCCCCCCCCHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCHHHCCCCCCCE
LQIDTTEPGLQIYNGSSLHDVPISLHDQRVLRPFSGIALEPQGWPDAPHNRAFPSIVLRP
EEEECCCCCEEEECCCCEEECCCEECCHHHHCCCCCEEECCCCCCCCCCCCCCCEEEECC
GQTYRQKTIYRIWHELSEPATF
CCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MISLRSASLTAQILPFGATLAGLWLDGHPDSLVIGSSDAEAYTDHLRYFGAVIGPIANRI
CCEECCCCCEEEEEECCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHC
SGAALQIGGAAFSMEANEGSACLHSGASGLHARMWTVLRCSAAAVSLRCELPDGANGLPG
CCCEEEECCEEEEEECCCCCHHHHCCCCCHHHHHHHHHHHCCEEEEEEEECCCCCCCCCC
NRRVEAHYELTDDGQLVLELTAQSDRATAINLAHHPYWNLGNADTIQNHHLMVYADTYLP
CCEEEEEEEECCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCEECCCEEEEEEECCCC
VDQQILPTGEIAPVAQTAYDFQTLRAIPIDRTLDANLCLAKIRRARPEPAARLRGPSGVT
CCCCCCCCCCCCHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCHHHCCCCCCCE
LQIDTTEPGLQIYNGSSLHDVPISLHDQRVLRPFSGIALEPQGWPDAPHNRAFPSIVLRP
EEEECCCCCEEEECCCCEEECCCEECCHHHHCCCCCEEECCCCCCCCCCCCCCCEEEECC
GQTYRQKTIYRIWHELSEPATF
CCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3012466; 3531172 [H]