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The map label for this gene is cheA [H]

Identifier: 110680250

GI number: 110680250

Start: 2928050

End: 2930272

Strand: Direct

Name: cheA [H]

Synonym: RD1_3059

Alternate gene names: 110680250

Gene position: 2928050-2930272 (Clockwise)

Preceding gene: 110680249

Following gene: 110680251

Centisome position: 70.84

GC content: 52.36

Gene sequence:

>2223_bases
ATGGCGGAAATCCGAGCGTCTTTCTTCATTGAATGCGAAGAACTACTGGAAGCGCTGCAGGATGGTCTCGAAGCTCTCAA
TGACGGCGCGGGTGATCCTGAAACCATCAACGTTGTGTTCAGAGCGGTTCACTCCATCAAAGGCGGTGCCGGGGCATTTG
GTCTGGAAGCGCTTGTCCGATTTGCGCATCGGTTCGAGACGGTGCTTGATGAAATCCGAGCTGGGCGCATGGTCGCGGAT
GCGAATGCGCTCAAATTGTTTTTTCAATGCTCGGATCATCTCTCTGATCTCGTGCGCATCAGCCGTGACGCCGGCACGCT
TCCGGAGGATGAAACCTCCAAGCTCCTTGCACTGTTGGATGAGTTGCTAGGCGAAAACGGCGCGATACCCGAAGAAGAGG
AAGTCGAAGAGGAAATTGACTTTCAACCTGCCGCTTTATCGTTTGATCTCGATTTGGGTGATGCCGATGAGGGGGATGCT
CTCGACCTGTTGCCGCCGTTGACTTTTGATGAAGACGAAGGCCCAAGAAGCTCCAGATATGAGATTACATTTAAACCGGA
GAATGAGCTTTACGAAACAGGAAACGAACCTTTTCAAATCCTGCGCGCACTGGATGAAATGGGTGAGTGTAAAGTTACGT
GCAAAACGGATCAGGTACCTGAACTGGCGAGCCTCGCCCCCGAAAATGCATATCTGTCATGGCACATTGAGCTTACAACG
GATGTTGAAGAAGCTGAAATCTCGGCAGCATTTGAATTTGTAGAGGGACTTTGTCTCTTGGACATCAAGAGTGTCGACGA
TGAAGACACGCAGGAAGAACAGAACGGCTCTGAAGACAGCACCGCCGACGCGGACCCGATCAGTGAATTGACCACACCGG
CTGCCAAGGTGGAAGAAGTTTCGGAACCCGACCCCATTGCGGAACTCTCCAAACCAGCCCCAGAAGCAACAGAAAAGGTC
GTGGCACCACAGAAAGCCGAACAGAAAACACCCACCCCGGCTGCACCGGCGAAATCAGTCGTTCGAGTGGATCTCGACAG
AATTGAACGTTTGGTGAACCTTGTTGGCGAATTGGTAATCAATCAGGCGATGCTCTCGCAGAGCCTTGAAAGCTCGGGGT
TATCTCCGCACTCAGACGCAATGAACGGGCTGGAAGAGTTTCAGCGACTGACCCGTGACATCCAGGACAGCGTGATGATG
ATCCGCGCGCAGCCGGTTAAATCCCTCTTTCAACGCATGTCGAGAATCGTTCGAGAGTCATCGGCCGCCGTTGATAAAGA
CGTCCGCCTTGTCACCAATGGCGAGGGAACCGAAGTCGATAAGACAGTTATCGAGCGTCTGGCCGATCCTCTTACGCATA
TGATCAGGAATGCAGTTGATCATGGCCTGGAGACAACAGACGCGAGGCTTGCGGCTGGCAAACCAGCCCAAGGCCAGGTT
AAACTTACGGCTGCACACAGATCCGGACGGGTGGTGATAGAAGTTGCCGATGATGGGGCTGGCATTAACCGCCCAAAGGT
TTTGCAAATTGCTATCGACAAAGGGTTGATCCCCAAAGACGCATCGTTGTCTGAAAGTGAAATTGACAACTTGCTGTTCC
TGCCGGGGTTTTCGACGGCGTCAGTTGTGTCAGACCTTTCAGGTCGTGGCGTGGGGATGGACGTTGTACGAACCGCGATT
CAAGCTCTGGGCGGCCGCATCACGATTTCGTCGACACCGGGTTCAGGCACTACTTTTTCAATATCTTTGCCACTTACTCT
GGCCGTCTTGGACGGAATGGTTGTTCAGGTTGCAGATGAGACCCTTGTCCTCCCCCTGAATGTGGTGATTGAAACGCTAA
CACTCAGTAATGATGATGTTGAGATGGTCCGCCCCGGCGCAAACGTTGTCAGGGTAAGAAGTGGCTTTGTGCCTCTTTTC
GATCTAGGCGAAGAACTGGGATACCGGGGCCCCATTGATGACTACGAAGGGTCAGTCGTCCTTTTGATCGCACATGAAGA
CGAAAGCCGCGCTGCTCTCATAATCGATAGCATACAGGACCAGAGACAAGTCGTCATCAAGGGTTTGGATGACAGCTTCT
ATCGCGCCCCTGGGATAGCCGCCGCTACTATTCTCGGAGATGGCCAGATCGCTCTGATTTTGGACACGTCAGACATTATC
ACAAACGCAATCGGCTCAAACATATCTGGGCATAGTTCTACTGTATCAGGAGCAACATCATGA

Upstream 100 bases:

>100_bases
CACCGGATGGATCGTGAAGCCGTTTGACCCCAACAAGCTGGTCAAAGCGCTCCAAATGGTTGCCGGGTAAGAGGCTGAAA
TGACTGATTCAAATGATCCT

Downstream 100 bases:

>100_bases
GTGAAAAAGATACGCCGGAGACTCTGGAACTCCTGACGTTCCAGCTCGCAGACCAAGAATACTCCCTGGATATCATGTCT
GTAAGAGAAATTCGCGGTTG

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 740; Mature: 739

Protein sequence:

>740_residues
MAEIRASFFIECEELLEALQDGLEALNDGAGDPETINVVFRAVHSIKGGAGAFGLEALVRFAHRFETVLDEIRAGRMVAD
ANALKLFFQCSDHLSDLVRISRDAGTLPEDETSKLLALLDELLGENGAIPEEEEVEEEIDFQPAALSFDLDLGDADEGDA
LDLLPPLTFDEDEGPRSSRYEITFKPENELYETGNEPFQILRALDEMGECKVTCKTDQVPELASLAPENAYLSWHIELTT
DVEEAEISAAFEFVEGLCLLDIKSVDDEDTQEEQNGSEDSTADADPISELTTPAAKVEEVSEPDPIAELSKPAPEATEKV
VAPQKAEQKTPTPAAPAKSVVRVDLDRIERLVNLVGELVINQAMLSQSLESSGLSPHSDAMNGLEEFQRLTRDIQDSVMM
IRAQPVKSLFQRMSRIVRESSAAVDKDVRLVTNGEGTEVDKTVIERLADPLTHMIRNAVDHGLETTDARLAAGKPAQGQV
KLTAAHRSGRVVIEVADDGAGINRPKVLQIAIDKGLIPKDASLSESEIDNLLFLPGFSTASVVSDLSGRGVGMDVVRTAI
QALGGRITISSTPGSGTTFSISLPLTLAVLDGMVVQVADETLVLPLNVVIETLTLSNDDVEMVRPGANVVRVRSGFVPLF
DLGEELGYRGPIDDYEGSVVLLIAHEDESRAALIIDSIQDQRQVVIKGLDDSFYRAPGIAAATILGDGQIALILDTSDII
TNAIGSNISGHSSTVSGATS

Sequences:

>Translated_740_residues
MAEIRASFFIECEELLEALQDGLEALNDGAGDPETINVVFRAVHSIKGGAGAFGLEALVRFAHRFETVLDEIRAGRMVAD
ANALKLFFQCSDHLSDLVRISRDAGTLPEDETSKLLALLDELLGENGAIPEEEEVEEEIDFQPAALSFDLDLGDADEGDA
LDLLPPLTFDEDEGPRSSRYEITFKPENELYETGNEPFQILRALDEMGECKVTCKTDQVPELASLAPENAYLSWHIELTT
DVEEAEISAAFEFVEGLCLLDIKSVDDEDTQEEQNGSEDSTADADPISELTTPAAKVEEVSEPDPIAELSKPAPEATEKV
VAPQKAEQKTPTPAAPAKSVVRVDLDRIERLVNLVGELVINQAMLSQSLESSGLSPHSDAMNGLEEFQRLTRDIQDSVMM
IRAQPVKSLFQRMSRIVRESSAAVDKDVRLVTNGEGTEVDKTVIERLADPLTHMIRNAVDHGLETTDARLAAGKPAQGQV
KLTAAHRSGRVVIEVADDGAGINRPKVLQIAIDKGLIPKDASLSESEIDNLLFLPGFSTASVVSDLSGRGVGMDVVRTAI
QALGGRITISSTPGSGTTFSISLPLTLAVLDGMVVQVADETLVLPLNVVIETLTLSNDDVEMVRPGANVVRVRSGFVPLF
DLGEELGYRGPIDDYEGSVVLLIAHEDESRAALIIDSIQDQRQVVIKGLDDSFYRAPGIAAATILGDGQIALILDTSDII
TNAIGSNISGHSSTVSGATS
>Mature_739_residues
AEIRASFFIECEELLEALQDGLEALNDGAGDPETINVVFRAVHSIKGGAGAFGLEALVRFAHRFETVLDEIRAGRMVADA
NALKLFFQCSDHLSDLVRISRDAGTLPEDETSKLLALLDELLGENGAIPEEEEVEEEIDFQPAALSFDLDLGDADEGDAL
DLLPPLTFDEDEGPRSSRYEITFKPENELYETGNEPFQILRALDEMGECKVTCKTDQVPELASLAPENAYLSWHIELTTD
VEEAEISAAFEFVEGLCLLDIKSVDDEDTQEEQNGSEDSTADADPISELTTPAAKVEEVSEPDPIAELSKPAPEATEKVV
APQKAEQKTPTPAAPAKSVVRVDLDRIERLVNLVGELVINQAMLSQSLESSGLSPHSDAMNGLEEFQRLTRDIQDSVMMI
RAQPVKSLFQRMSRIVRESSAAVDKDVRLVTNGEGTEVDKTVIERLADPLTHMIRNAVDHGLETTDARLAAGKPAQGQVK
LTAAHRSGRVVIEVADDGAGINRPKVLQIAIDKGLIPKDASLSESEIDNLLFLPGFSTASVVSDLSGRGVGMDVVRTAIQ
ALGGRITISSTPGSGTTFSISLPLTLAVLDGMVVQVADETLVLPLNVVIETLTLSNDDVEMVRPGANVVRVRSGFVPLFD
LGEELGYRGPIDDYEGSVVLLIAHEDESRAALIIDSIQDQRQVVIKGLDDSFYRAPGIAAATILGDGQIALILDTSDIIT
NAIGSNISGHSSTVSGATS

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=399, Percent_Identity=45.1127819548872, Blast_Score=338, Evalue=7e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79542; Mature: 79411

Theoretical pI: Translated: 4.03; Mature: 4.03

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS00687 ALDEHYDE_DEHYDR_GLU ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEIRASFFIECEELLEALQDGLEALNDGAGDPETINVVFRAVHSIKGGAGAFGLEALVR
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHH
FAHRFETVLDEIRAGRMVADANALKLFFQCSDHLSDLVRISRDAGTLPEDETSKLLALLD
HHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ELLGENGAIPEEEEVEEEIDFQPAALSFDLDLGDADEGDALDLLPPLTFDEDEGPRSSRY
HHHCCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCCCCEECCCCCCCCCCCCCCCCEE
EITFKPENELYETGNEPFQILRALDEMGECKVTCKTDQVPELASLAPENAYLSWHIELTT
EEEECCCHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHCCCCCCEEEEEEEEEC
DVEEAEISAAFEFVEGLCLLDIKSVDDEDTQEEQNGSEDSTADADPISELTTPAAKVEEV
CCHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHCCCCCCCCCCCCHHHHCCCHHHHHHC
SEPDPIAELSKPAPEATEKVVAPQKAEQKTPTPAAPAKSVVRVDLDRIERLVNLVGELVI
CCCCCHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NQAMLSQSLESSGLSPHSDAMNGLEEFQRLTRDIQDSVMMIRAQPVKSLFQRMSRIVRES
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
SAAVDKDVRLVTNGEGTEVDKTVIERLADPLTHMIRNAVDHGLETTDARLAAGKPAQGQV
HHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCEE
KLTAAHRSGRVVIEVADDGAGINRPKVLQIAIDKGLIPKDASLSESEIDNLLFLPGFSTA
EEEEECCCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHCCCEEEECCCCHH
SVVSDLSGRGVGMDVVRTAIQALGGRITISSTPGSGTTFSISLPLTLAVLDGMVVQVADE
HHHHHHCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCHHHHHHCCHHEEECCC
TLVLPLNVVIETLTLSNDDVEMVRPGANVVRVRSGFVPLFDLGEELGYRGPIDDYEGSVV
EEEEEHHHHHHHHCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCCCEE
LLIAHEDESRAALIIDSIQDQRQVVIKGLDDSFYRAPGIAAATILGDGQIALILDTSDII
EEEEECCCCCEEEEEHHHHHHHHHHHCCCCCHHHCCCCCEEEEEECCCEEEEEEECHHHH
TNAIGSNISGHSSTVSGATS
HHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AEIRASFFIECEELLEALQDGLEALNDGAGDPETINVVFRAVHSIKGGAGAFGLEALVR
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHH
FAHRFETVLDEIRAGRMVADANALKLFFQCSDHLSDLVRISRDAGTLPEDETSKLLALLD
HHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ELLGENGAIPEEEEVEEEIDFQPAALSFDLDLGDADEGDALDLLPPLTFDEDEGPRSSRY
HHHCCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCCCCEECCCCCCCCCCCCCCCCEE
EITFKPENELYETGNEPFQILRALDEMGECKVTCKTDQVPELASLAPENAYLSWHIELTT
EEEECCCHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHCCCCCCEEEEEEEEEC
DVEEAEISAAFEFVEGLCLLDIKSVDDEDTQEEQNGSEDSTADADPISELTTPAAKVEEV
CCHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHCCCCCCCCCCCCHHHHCCCHHHHHHC
SEPDPIAELSKPAPEATEKVVAPQKAEQKTPTPAAPAKSVVRVDLDRIERLVNLVGELVI
CCCCCHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NQAMLSQSLESSGLSPHSDAMNGLEEFQRLTRDIQDSVMMIRAQPVKSLFQRMSRIVRES
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
SAAVDKDVRLVTNGEGTEVDKTVIERLADPLTHMIRNAVDHGLETTDARLAAGKPAQGQV
HHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCEE
KLTAAHRSGRVVIEVADDGAGINRPKVLQIAIDKGLIPKDASLSESEIDNLLFLPGFSTA
EEEEECCCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHCCCEEEECCCCHH
SVVSDLSGRGVGMDVVRTAIQALGGRITISSTPGSGTTFSISLPLTLAVLDGMVVQVADE
HHHHHHCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCHHHHHHCCHHEEECCC
TLVLPLNVVIETLTLSNDDVEMVRPGANVVRVRSGFVPLFDLGEELGYRGPIDDYEGSVV
EEEEEHHHHHHHHCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCCCEE
LLIAHEDESRAALIIDSIQDQRQVVIKGLDDSFYRAPGIAAATILGDGQIALILDTSDII
EEEEECCCCCEEEEEHHHHHHHHHHHCCCCCHHHCCCCCEEEEEECCCEEEEEEECHHHH
TNAIGSNISGHSSTVSGATS
HHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7494484 [H]