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The map label for this gene is hesB [H]

Identifier: 110680159

GI number: 110680159

Start: 2838162

End: 2838506

Strand: Direct

Name: hesB [H]

Synonym: RD1_2960

Alternate gene names: 110680159

Gene position: 2838162-2838506 (Clockwise)

Preceding gene: 110680158

Following gene: 110680160

Centisome position: 68.67

GC content: 56.81

Gene sequence:

>345_bases
ATGTTTGGTATTCCCGGCAAACCCCCGGTCACACTGACACCGAAAGCCTGCGCCCAGGTTGCAAAGCTCATGGCATCCGC
AGGCCACGCAGGCTTGCGCATCGGCATCAAGAAGGGCGGCTGTGCGGGCATGGAATACACGATGGAATACGTCGAAGACG
CCGATCCCAATGACGAGGTGGTCGAGCAGGACGGCGCGCGTGTCATGATTGCCCCGATGGCGCAGATGTTCCTCTTCGGC
ACTGAAATCGACTACGAAACCAGTCTTCTGGAATCCGGCTTTAAGTTCAGAAACCCGAACGTGACCGAAGCATGCGGTTG
CGGTGAATCCATCAAATTCGGCTAA

Upstream 100 bases:

>100_bases
CGCGCGATGTTGCCCAGGGTGTCACGGTTGCGGGAAATCCCGCGCGACCGCTTGTTCCACAGGCATCAAGTCATTAGATT
AAAGGCAAAGGAGTCGTCCC

Downstream 100 bases:

>100_bases
CGCGCTGTCCTTATCGCGCAAGGCGGGCAGTTGCAGGATCAGCTAGGCAACACGACGGCACAACAGCATTTGCACCGTTG
CACGGCGGCTGTTAGCAAGA

Product: HesB-like iron-sulfur cluster assembly protein, putative

Products: NA

Alternate protein names: Iron-sulfur cluster assembly protein [H]

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MFGIPGKPPVTLTPKACAQVAKLMASAGHAGLRIGIKKGGCAGMEYTMEYVEDADPNDEVVEQDGARVMIAPMAQMFLFG
TEIDYETSLLESGFKFRNPNVTEACGCGESIKFG

Sequences:

>Translated_114_residues
MFGIPGKPPVTLTPKACAQVAKLMASAGHAGLRIGIKKGGCAGMEYTMEYVEDADPNDEVVEQDGARVMIAPMAQMFLFG
TEIDYETSLLESGFKFRNPNVTEACGCGESIKFG
>Mature_114_residues
MFGIPGKPPVTLTPKACAQVAKLMASAGHAGLRIGIKKGGCAGMEYTMEYVEDADPNDEVVEQDGARVMIAPMAQMFLFG
TEIDYETSLLESGFKFRNPNVTEACGCGESIKFG

Specific function: Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that iscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transi

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI52426768, Length=107, Percent_Identity=43.9252336448598, Blast_Score=102, Evalue=9e-23,
Organism=Homo sapiens, GI160420328, Length=109, Percent_Identity=32.1100917431193, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788877, Length=103, Percent_Identity=42.7184466019417, Blast_Score=95, Evalue=1e-21,
Organism=Escherichia coli, GI1787974, Length=103, Percent_Identity=40.7766990291262, Blast_Score=87, Evalue=2e-19,
Organism=Escherichia coli, GI1786351, Length=106, Percent_Identity=32.0754716981132, Blast_Score=68, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193209025, Length=105, Percent_Identity=47.6190476190476, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI25146411, Length=105, Percent_Identity=47.6190476190476, Blast_Score=107, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323001, Length=101, Percent_Identity=38.6138613861386, Blast_Score=87, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24642263, Length=108, Percent_Identity=43.5185185185185, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR011302 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 12156; Mature: 12156

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
9.6 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
9.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGIPGKPPVTLTPKACAQVAKLMASAGHAGLRIGIKKGGCAGMEYTMEYVEDADPNDEV
CCCCCCCCCEEECHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCHHH
VEQDGARVMIAPMAQMFLFGTEIDYETSLLESGFKFRNPNVTEACGCGESIKFG
HHCCCCEEEEHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCHHCCCCCCCCCC
>Mature Secondary Structure
MFGIPGKPPVTLTPKACAQVAKLMASAGHAGLRIGIKKGGCAGMEYTMEYVEDADPNDEV
CCCCCCCCCEEECHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCHHH
VEQDGARVMIAPMAQMFLFGTEIDYETSLLESGFKFRNPNVTEACGCGESIKFG
HHCCCCEEEEHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]