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The map label for this gene is glpD [H]

Identifier: 110680088

GI number: 110680088

Start: 2761375

End: 2762973

Strand: Reverse

Name: glpD [H]

Synonym: RD1_2884

Alternate gene names: 110680088

Gene position: 2762973-2761375 (Counterclockwise)

Preceding gene: 110680090

Following gene: 110680087

Centisome position: 66.85

GC content: 57.97

Gene sequence:

>1599_bases
GTGCCCAATGATCAAGAGAAGCCCTACGATCTGTTCATCATCGGTGGTGGCATAAACGGCTGCGGTATCGCGCGCGATGC
GGCCGGGCGGGGCCTGCATGTTGCGCTGGCAGAAATGAACGATCTGGCCTCGGCCACATCTTCTGCATCGACCAAGCTGT
TTCATGGCGGTCTGCGCTATCTTGAGTATTTCGAGATCAATCTGGTCAAACATGCTCTGGCAGAGCGTGAAGTGCTGTTG
AAAGCCATGCCGCATATCAGTTGGCCCATGCGCTTTGTGTTGCCCTATCACCGCGACATGAGGTTCGAGGGCAGCACGCC
AACCTCGCGCATCCTCAATACCGTAATGCCCTGGATGAAGGGGCGGCGGCCTGCATGGCTGATCCGGTTTGGTCTTTTCC
TGTATGACAATCTGGGTGGTCGCGACATCCTGCCGGGGACAAAAACGCTGGATTTGCGCGGGGGGCCTGAGGGCGCACCA
CTGGTGAAAAAGTTCGAAAAGGCTTTTGAATATTCAGATTGCTGGGTTGAGGATTCGCGCCTTGTCGTTCTGAACGCGCG
TGATGCTGCCGCGCGGGGAGCATCCGTGATGGTGCGCACCAAAGTCGTGTCTGCCGCGCGCGTCGACGATCTGTGGGAGG
TGAGCCTGCAGGACGTGACCACAGGGCAGATGCGCAAGCTGCGGGCGCGCATGCTGGTCAATGCAGGCGGGCCGTGGGTC
GGGGATATCATCCAGCAAAAGGTGCGGATAAACTCGACCGAAGGCGTGCGATTGGTGCGCGGCAGCCACATCGTGACGCG
CAAACTCTATGATCATGACAAATGTTACTTTTTTCAGGGCATGGACGGGCGCATCATCTTTGCCATTCCCTATGAGACGG
ATTTCACGTTGATCGGGACGACGGATGCAGAGCATCCCGACCCGTCGGTGTCGCCTGAATGCACGCCTCAGGAGCGTGAT
TATCTGATTGATTTCGCCAACCAGTATTTCGACCATGACATAAGCCGCGACGATGTGGTCTGGACCTATTCCGGGGTGCG
CCCGCTTTACGATGATGGGGCAAGCAGTGCGACGGCGGCGACGCGGGACTATACGCTCAAGGTGGATGAGGCAGGTGGCG
CGCCGATCCTGAATGTCTTTGGCGGCAAGATCACGACCTACCGCAAGCTGGCAGAGGATGCGATGGAGCGGATCGTGCCG
TTCTTTCCCGGCACCTCGGGGCATTGGACGGCGGGTGTGCCCTTGCCGGGCGGCGATTTCGCGGTCGGGGATTTCGACAC
GCTTGTCGCGCGGCTGCGTGATGATTTTCCTTTTCTTTCGCATTTTTGCGCACGCAGGCTGGTGCGCGCCTATGGCACCG
AAAGCTGGGACATCATGGCGGGTGCACAGAAGGTTGAAGAATTGGGCGAACACTTCGGTCATGGGTTACGCGCGCGCGAG
GTGCTCTGGCTGATGACCCATGAATATGCGCAAACAGCCGAAGATATCCTGTGGCGGCGCAACAAATTGGGCTTGCGCAT
GAGTCCGCAGGAAGTTTCTGTTCTGGATGACTTTATGCAGGCACACAGGCTAAAAGAAGGCTCTGACGCTGCACAATAA

Upstream 100 bases:

>100_bases
TCTTTTGTACATTAAACGAAAAATTTCGAAGATAAATGCTTGAATGCGCAGGATGGCTGCGTTAGGCGAAATGCACTTGG
ATGACGAGAAAGACCGCGCA

Downstream 100 bases:

>100_bases
CTTGGGGGAGGGGTGCATGACCCATATCTTGGCCATTGATCAGGGAACCACGTCGTCACGCGCGATCATATTTGATGCGT
CGATGAACATCACCGCATCC

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 531

Protein sequence:

>532_residues
MPNDQEKPYDLFIIGGGINGCGIARDAAGRGLHVALAEMNDLASATSSASTKLFHGGLRYLEYFEINLVKHALAEREVLL
KAMPHISWPMRFVLPYHRDMRFEGSTPTSRILNTVMPWMKGRRPAWLIRFGLFLYDNLGGRDILPGTKTLDLRGGPEGAP
LVKKFEKAFEYSDCWVEDSRLVVLNARDAAARGASVMVRTKVVSAARVDDLWEVSLQDVTTGQMRKLRARMLVNAGGPWV
GDIIQQKVRINSTEGVRLVRGSHIVTRKLYDHDKCYFFQGMDGRIIFAIPYETDFTLIGTTDAEHPDPSVSPECTPQERD
YLIDFANQYFDHDISRDDVVWTYSGVRPLYDDGASSATAATRDYTLKVDEAGGAPILNVFGGKITTYRKLAEDAMERIVP
FFPGTSGHWTAGVPLPGGDFAVGDFDTLVARLRDDFPFLSHFCARRLVRAYGTESWDIMAGAQKVEELGEHFGHGLRARE
VLWLMTHEYAQTAEDILWRRNKLGLRMSPQEVSVLDDFMQAHRLKEGSDAAQ

Sequences:

>Translated_532_residues
MPNDQEKPYDLFIIGGGINGCGIARDAAGRGLHVALAEMNDLASATSSASTKLFHGGLRYLEYFEINLVKHALAEREVLL
KAMPHISWPMRFVLPYHRDMRFEGSTPTSRILNTVMPWMKGRRPAWLIRFGLFLYDNLGGRDILPGTKTLDLRGGPEGAP
LVKKFEKAFEYSDCWVEDSRLVVLNARDAAARGASVMVRTKVVSAARVDDLWEVSLQDVTTGQMRKLRARMLVNAGGPWV
GDIIQQKVRINSTEGVRLVRGSHIVTRKLYDHDKCYFFQGMDGRIIFAIPYETDFTLIGTTDAEHPDPSVSPECTPQERD
YLIDFANQYFDHDISRDDVVWTYSGVRPLYDDGASSATAATRDYTLKVDEAGGAPILNVFGGKITTYRKLAEDAMERIVP
FFPGTSGHWTAGVPLPGGDFAVGDFDTLVARLRDDFPFLSHFCARRLVRAYGTESWDIMAGAQKVEELGEHFGHGLRARE
VLWLMTHEYAQTAEDILWRRNKLGLRMSPQEVSVLDDFMQAHRLKEGSDAAQ
>Mature_531_residues
PNDQEKPYDLFIIGGGINGCGIARDAAGRGLHVALAEMNDLASATSSASTKLFHGGLRYLEYFEINLVKHALAEREVLLK
AMPHISWPMRFVLPYHRDMRFEGSTPTSRILNTVMPWMKGRRPAWLIRFGLFLYDNLGGRDILPGTKTLDLRGGPEGAPL
VKKFEKAFEYSDCWVEDSRLVVLNARDAAARGASVMVRTKVVSAARVDDLWEVSLQDVTTGQMRKLRARMLVNAGGPWVG
DIIQQKVRINSTEGVRLVRGSHIVTRKLYDHDKCYFFQGMDGRIIFAIPYETDFTLIGTTDAEHPDPSVSPECTPQERDY
LIDFANQYFDHDISRDDVVWTYSGVRPLYDDGASSATAATRDYTLKVDEAGGAPILNVFGGKITTYRKLAEDAMERIVPF
FPGTSGHWTAGVPLPGGDFAVGDFDTLVARLRDDFPFLSHFCARRLVRAYGTESWDIMAGAQKVEELGEHFGHGLRAREV
LWLMTHEYAQTAEDILWRRNKLGLRMSPQEVSVLDDFMQAHRLKEGSDAAQ

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=540, Percent_Identity=29.8148148148148, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI285002231, Length=540, Percent_Identity=29.8148148148148, Blast_Score=178, Evalue=1e-44,
Organism=Escherichia coli, GI2367226, Length=489, Percent_Identity=44.9897750511247, Blast_Score=421, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI115534726, Length=532, Percent_Identity=27.0676691729323, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17509253, Length=544, Percent_Identity=28.125, Blast_Score=145, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6322036, Length=558, Percent_Identity=26.5232974910394, Blast_Score=136, Evalue=8e-33,
Organism=Drosophila melanogaster, GI161077125, Length=547, Percent_Identity=28.7020109689214, Blast_Score=153, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24653942, Length=547, Percent_Identity=28.7020109689214, Blast_Score=153, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24653944, Length=547, Percent_Identity=28.7020109689214, Blast_Score=153, Evalue=4e-37,
Organism=Drosophila melanogaster, GI20130025, Length=547, Percent_Identity=28.7020109689214, Blast_Score=153, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24586295, Length=539, Percent_Identity=26.9016697588126, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI19921278, Length=520, Percent_Identity=22.5, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 59660; Mature: 59528

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNDQEKPYDLFIIGGGINGCGIARDAAGRGLHVALAEMNDLASATSSASTKLFHGGLRY
CCCCCCCCEEEEEECCCCCCCCCCHHCCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHH
LEYFEINLVKHALAEREVLLKAMPHISWPMRFVLPYHRDMRFEGSTPTSRILNTVMPWMK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEECCCCCCEEECCCCCHHHHHHHHHHHHC
GRRPAWLIRFGLFLYDNLGGRDILPGTKTLDLRGGPEGAPLVKKFEKAFEYSDCWVEDSR
CCCCEEHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCEEECCE
LVVLNARDAAARGASVMVRTKVVSAARVDDLWEVSLQDVTTGQMRKLRARMLVNAGGPWV
EEEEECCCCCCCCCEEEEEHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHH
GDIIQQKVRINSTEGVRLVRGSHIVTRKLYDHDKCYFFQGMDGRIIFAIPYETDFTLIGT
HHHHHHHHCCCCCCCEEEEECCEEEEHHHCCCCCEEEEECCCCEEEEEEECCCCEEEEEC
TDAEHPDPSVSPECTPQERDYLIDFANQYFDHDISRDDVVWTYSGVRPLYDDGASSATAA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCC
TRDYTLKVDEAGGAPILNVFGGKITTYRKLAEDAMERIVPFFPGTSGHWTAGVPLPGGDF
CCEEEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCE
AVGDFDTLVARLRDDFPFLSHFCARRLVRAYGTESWDIMAGAQKVEELGEHFGHGLRARE
ECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHH
VLWLMTHEYAQTAEDILWRRNKLGLRMSPQEVSVLDDFMQAHRLKEGSDAAQ
HHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PNDQEKPYDLFIIGGGINGCGIARDAAGRGLHVALAEMNDLASATSSASTKLFHGGLRY
CCCCCCCEEEEEECCCCCCCCCCHHCCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHH
LEYFEINLVKHALAEREVLLKAMPHISWPMRFVLPYHRDMRFEGSTPTSRILNTVMPWMK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEECCCCCCEEECCCCCHHHHHHHHHHHHC
GRRPAWLIRFGLFLYDNLGGRDILPGTKTLDLRGGPEGAPLVKKFEKAFEYSDCWVEDSR
CCCCEEHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCEEECCE
LVVLNARDAAARGASVMVRTKVVSAARVDDLWEVSLQDVTTGQMRKLRARMLVNAGGPWV
EEEEECCCCCCCCCEEEEEHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHH
GDIIQQKVRINSTEGVRLVRGSHIVTRKLYDHDKCYFFQGMDGRIIFAIPYETDFTLIGT
HHHHHHHHCCCCCCCEEEEECCEEEEHHHCCCCCEEEEECCCCEEEEEEECCCCEEEEEC
TDAEHPDPSVSPECTPQERDYLIDFANQYFDHDISRDDVVWTYSGVRPLYDDGASSATAA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCC
TRDYTLKVDEAGGAPILNVFGGKITTYRKLAEDAMERIVPFFPGTSGHWTAGVPLPGGDF
CCEEEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCE
AVGDFDTLVARLRDDFPFLSHFCARRLVRAYGTESWDIMAGAQKVEELGEHFGHGLRARE
ECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHH
VLWLMTHEYAQTAEDILWRRNKLGLRMSPQEVSVLDDFMQAHRLKEGSDAAQ
HHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]