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The map label for this gene is hfq

Identifier: 110679966

GI number: 110679966

Start: 2627417

End: 2627656

Strand: Reverse

Name: hfq

Synonym: RD1_2755

Alternate gene names: 110679966

Gene position: 2627656-2627417 (Counterclockwise)

Preceding gene: 110679967

Following gene: 110679965

Centisome position: 63.58

GC content: 52.5

Gene sequence:

>240_bases
ATGGCGTCGGACAGACAGAACCTTCAGGATGCGTTCCTGAACCATGTGCGCAAGACAAAAGTTCCTGTGACCATCTTTCT
GATCAATGGAGTGAAGCTGCAGGGCGTGATCACGTGGTTTGACAATTTCTGCGTGTTGTTGCGCCGGGATGGGCAATCGC
AGCTGGTGTATAAGCATGCCATTTCCACGATCATGCCGAGCCAGCCCATCAGTCTTTACGAGGGCGAAGACGCTTCTTGA

Upstream 100 bases:

>100_bases
CTGTTTTTAGGGCTGGAAACTCCGGGAACGGGGCTTCATAATCACGTCGAGGGACGAGTTCGATCTGCGGGCTCTGGCAA
GAATAAAGGCGAGGAAGACA

Downstream 100 bases:

>100_bases
GCAAGCCACCCTTTCAAATTGATGAAACCATCCAGACGCGTGTGACCCGCGCCTGGGTTCTGCATCCTGAAATAAAATCC
GACCCTGATCGCCGACTGGC

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 79; Mature: 78

Protein sequence:

>79_residues
MASDRQNLQDAFLNHVRKTKVPVTIFLINGVKLQGVITWFDNFCVLLRRDGQSQLVYKHAISTIMPSQPISLYEGEDAS

Sequences:

>Translated_79_residues
MASDRQNLQDAFLNHVRKTKVPVTIFLINGVKLQGVITWFDNFCVLLRRDGQSQLVYKHAISTIMPSQPISLYEGEDAS
>Mature_78_residues
ASDRQNLQDAFLNHVRKTKVPVTIFLINGVKLQGVITWFDNFCVLLRRDGQSQLVYKHAISTIMPSQPISLYEGEDAS

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=68, Percent_Identity=57.3529411764706, Blast_Score=87, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_ROSDO (Q165Q6)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_682973.1
- ProteinModelPortal:   Q165Q6
- SMR:   Q165Q6
- STRING:   Q165Q6
- GeneID:   4195914
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_2755
- eggNOG:   COG1923
- HOGENOM:   HBG645207
- OMA:   KNTVTQM
- PhylomeDB:   Q165Q6
- ProtClustDB:   PRK00395
- BioCyc:   RDEN375451:RD1_2755-MONOMER
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 8964; Mature: 8833

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASDRQNLQDAFLNHVRKTKVPVTIFLINGVKLQGVITWFDNFCVLLRRDGQSQLVYKHA
CCCCHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEEECCCEEEEEECCCCCHHHHHHH
ISTIMPSQPISLYEGEDAS
HHHHCCCCCCEEECCCCCC
>Mature Secondary Structure 
ASDRQNLQDAFLNHVRKTKVPVTIFLINGVKLQGVITWFDNFCVLLRRDGQSQLVYKHA
CCCHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEEECCCEEEEEECCCCCHHHHHHH
ISTIMPSQPISLYEGEDAS
HHHHCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA