Click here to switch to the map view.

The map label for this gene is thiE [H]

Identifier: 110679944

GI number: 110679944

Start: 2602717

End: 2603337

Strand: Direct

Name: thiE [H]

Synonym: RD1_2730

Alternate gene names: 110679944

Gene position: 2602717-2603337 (Clockwise)

Preceding gene: 110679940

Following gene: 110679946

Centisome position: 62.97

GC content: 62.16

Gene sequence:

>621_bases
ATGGAATTGCCCGAAAAACCGCAGCTCTACCTGATCACGCCACCGGAATTTGAGTTGAGCAGTTTTCCCGATGTGCTGGC
GCGGGTTCTTGACACGCACAAAGTGGCTTGCGTGCGTCTGGAACTGGCGGCGCGCGATGAAGACACGGTGTCGCGCGCAG
CCGATGCGCTGCGCGAGGTGACCCATGCGCGCGATATCGCGCTGGTGCTGAGCGATCATTCGGTTCTGGCGGATCGCCTT
GGGCTGGATGGGGTCCATCTCAGCGATGCGGCCCGCTCCGTGCGTGAGACGCGCAAACTGCTGGGCGAAGACGCCATCAT
CGGCAGTTTTTGCGGCACATCGCGACACGACGGGATGTCCGCTGGAGAGGCGGGTGCCGATTACATCTGTTTCGGACCTG
TTGCGGCCTCGTCCCTTGGCGATGGCAGCTATGTCGCGCAGGAGGTCTTTGAGTGGTGGTCCGAGTTCATCGAGGTGCCC
GTGGTCGCCGAGGGCGGTCTTGATGCGGCCCGGATCGCACAGCTGACGCCCTTCACCGACTTTTTTGCCTTCGGACAAGA
AGTCTGGAGCGCCGAGTATCCCGCGCAGCGTTTGGGTGAACTGCTTGAGGCGATGGGCTAG

Upstream 100 bases:

>100_bases
CAGTCGGGCGGCAATTTTGACGCGCCGGGGTCAAATGCGTTTTCATTCCCCATGGTCTGCGGTAGGGCTTTGCGCACGTC
AGACCTCAAGGACCCCGAAT

Downstream 100 bases:

>100_bases
GGTTACAGAAATACCCGCTCGACACACCAATAGGCCCCGATGATGGCAATGATCAGCGAGGCCGGGATCGACACCGCCCG
GAACATCACCGCATAGGTGC

Product: thiamine-phosphate pyrophosphorylase, putative

Products: NA

Alternate protein names: TMP pyrophosphorylase; TMP-PPase; Thiamine-phosphate synthase [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MELPEKPQLYLITPPEFELSSFPDVLARVLDTHKVACVRLELAARDEDTVSRAADALREVTHARDIALVLSDHSVLADRL
GLDGVHLSDAARSVRETRKLLGEDAIIGSFCGTSRHDGMSAGEAGADYICFGPVAASSLGDGSYVAQEVFEWWSEFIEVP
VVAEGGLDAARIAQLTPFTDFFAFGQEVWSAEYPAQRLGELLEAMG

Sequences:

>Translated_206_residues
MELPEKPQLYLITPPEFELSSFPDVLARVLDTHKVACVRLELAARDEDTVSRAADALREVTHARDIALVLSDHSVLADRL
GLDGVHLSDAARSVRETRKLLGEDAIIGSFCGTSRHDGMSAGEAGADYICFGPVAASSLGDGSYVAQEVFEWWSEFIEVP
VVAEGGLDAARIAQLTPFTDFFAFGQEVWSAEYPAQRLGELLEAMG
>Mature_206_residues
MELPEKPQLYLITPPEFELSSFPDVLARVLDTHKVACVRLELAARDEDTVSRAADALREVTHARDIALVLSDHSVLADRL
GLDGVHLSDAARSVRETRKLLGEDAIIGSFCGTSRHDGMSAGEAGADYICFGPVAASSLGDGSYVAQEVFEWWSEFIEVP
VVAEGGLDAARIAQLTPFTDFFAFGQEVWSAEYPAQRLGELLEAMG

Specific function: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) [H]

COG id: COG0352

COG function: function code H; Thiamine monophosphate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TMP-PPase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022998
- InterPro:   IPR003733 [H]

Pfam domain/function: PF02581 TMP-TENI [H]

EC number: =2.5.1.3 [H]

Molecular weight: Translated: 22341; Mature: 22341

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELPEKPQLYLITPPEFELSSFPDVLARVLDTHKVACVRLELAARDEDTVSRAADALREV
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEEHHHHCCHHHHHHHHHHHHHH
THARDIALVLSDHSVLADRLGLDGVHLSDAARSVRETRKLLGEDAIIGSFCGTSRHDGMS
HHHHHEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCC
AGEAGADYICFGPVAASSLGDGSYVAQEVFEWWSEFIEVPVVAEGGLDAARIAQLTPFTD
CCCCCCCEEEECCHHHCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHCCHHH
FFAFGQEVWSAEYPAQRLGELLEAMG
HHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MELPEKPQLYLITPPEFELSSFPDVLARVLDTHKVACVRLELAARDEDTVSRAADALREV
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEEHHHHCCHHHHHHHHHHHHHH
THARDIALVLSDHSVLADRLGLDGVHLSDAARSVRETRKLLGEDAIIGSFCGTSRHDGMS
HHHHHEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCC
AGEAGADYICFGPVAASSLGDGSYVAQEVFEWWSEFIEVPVVAEGGLDAARIAQLTPFTD
CCCCCCCEEEECCHHHCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHCCHHH
FFAFGQEVWSAEYPAQRLGELLEAMG
HHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA