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The map label for this gene is recG [H]

Identifier: 110679833

GI number: 110679833

Start: 2486725

End: 2488815

Strand: Direct

Name: recG [H]

Synonym: RD1_2604

Alternate gene names: 110679833

Gene position: 2486725-2488815 (Clockwise)

Preceding gene: 110679832

Following gene: 110679836

Centisome position: 60.17

GC content: 58.78

Gene sequence:

>2091_bases
ATGAGCGGTCGTCCGGAAGCTCTGTTTGGCCTGTTTTCATCTCTTGAAACCCTTGACGGAGTTGGACCCAAAACAGCTGC
GAATTTTGCCGGTCTGGGCGTTCATGCGCCGCGGGATCTGCTTTTCACCTTGCCGATAAACGTCCTCGACCGGCGACACC
GCAATACGATTGAAGGGCTTGATTGCCCGACGATAACAACCGTTGCGGTCACCATCGGCGCGCATCGGCCACCCCGCACA
AAGGGAGCGGCCTACCGTATTTCTGTTGTCGACGCGGAAGCTGCGTTTCAACTGGTTTTCTTCCATGCGCGGGGCGACTA
CCTCGCACGTATCTTGCCGCAGGGCAGTCGCCGGGTCGTATCGGGCAAGTTGGAGCGTTTTGACGGGGTGTACCAGATGG
TGCATCCCGACTACATCTTGTCAGAGACCGAGGTCGACACGATCCCGCCTTTTGAACCTGTGTACCCCTTGACCTCCGGG
ATCACGCAAAAGGTGATGTTCAAGGCCACGCGGGCGGCATTGAAACTGCTCCCTGATTTGACCGAATGGATCGATCCCGG
CCAGATACGCAAGGCCGGGTGGCCTGATGTCAGGGAGGCTTTTACCCTTGCACATCGACCTCAGGCGCCTCAGGATATCT
CGATCACTGCCGCCGCGCGCGAGCGTCTGGCCTACGATGAAATGTTTGCACATCAAATGACGCTTGCCCTTGCGCGTTTG
ACAGAACGTCAGAAGAAAGGCCGCGCGACCCATGGCACGGGCGATTTGCAAATGCGATTGATTGAATCCTTGCCCTATCC
GCTGACCGGAGCGCAGCAACGTGCCATCGCGGATGTGAACCGTGATATGGCGGAAGCGGTCCGCATGAACCGTCTGCTTC
AAGGGGACGTGGGTGCTGGCAAAACGCTTGTTGCGTTTTTGGCCCTGCTGCGCGCGGTTGAAGGAGGCGGGCAGGGGGTT
TTGATGGCCCCAACGGAAATTCTGGCGCGTCAACACCTGCAAAGCCTGAAACCCATGGCCGAGCATGTTGGCGTCAGGCT
GGATATATTGACCGGGCGGGACACGGGGAAAGAGCGTACTGCAAAACTGGAGGACCTCGCAAATGGCAACATCGGGGTTT
TGGTTGGCACCCATGCTGTTTTCCAAAAGGGCGTGACATTCAGTGATCTGCGGCTGGCGGTGATTGATGAGCAACACCGT
TTTGGTGTCCAGCAAAGGATGGCGCTTGGGCAAAAGGGCGCAGCGGTTGATGTTCTGGTTATGACCGCGACACCGATCCC
GCGATCCTTGGCATTGGCGCAATTCGGGGACATGGATGTGTCTGTATTGGATGAGAAACCGCCGGGCCGGATGCCGATCA
AGACCGCGCTCGTGAGCGTTGATCGTATGGAGGAGGTCGTGTCGCGCCTGTGCGCCGTGGTAGAGGGCGGGCGTCAATGC
TATTGGGTGTGTCCGCTGGTGGAAGAAAGTGAAGTGGTCGACCTGACGGCGGCCGAGGACCGGTTCAAGAAGTTGCGTGC
GGCACTTGGCGAAGGCGTAGTGGGTCTTGTGCACGGACAGATGCCGGCGGCGGAGAAAGATGCCGCGATGGCGGGCTTTG
AGTCGGGCCAAACCAAGGTGTTGGTTGCCACGACTGTCATCGAAGTGGGCGTGAACGTGCCGAATGCGACGATCATGGTG
ATTGAGCGGGCAGAGTTTTTTGGGCTTGCACAGTTGCATCAACTCAGAGGGAGGGTCGGGCGCGGCACGGCGGCATCGAC
CTGTTTGCTTTTGTACCAACCGCCTCTTTCAGAAAGCGGTCAGCGGCGGCTGGAGGTGCTGCGTGAAACGGAAGACGGGT
TTATGATCGCTGAAACTGACCTGAAGATGCGCGGTGCAGGTGACGTCATCGGCACGGCGCAATCGGGGCTGCCGCGGTTC
TGGATAGCGGATCTGGAGCGACAGGCCGGGTTGATGCAGATCGCACAGTCGGACGCGCGCAAGCTGCTTGCGGATGATCC
GGGCCTTGCGACGCCAAGAGGGCAGGCCGCCCGCATGCTTTTGTGGCTCCTGCGCAAAGATGAATCAATCCGTTTGATTA
CAGTGGGTTAA

Upstream 100 bases:

>100_bases
TTGTTGCAGGACCCGGCGCAGGTTCAAAGGCCAAGAAAGCCGCCGAACTCGGTGTTCAAACCCTCGACGAAGACGGCTGG
CTGGCACTTATCGAGGGCTT

Downstream 100 bases:

>100_bases
CACTTTTGCTCCCAAATGTTCTTAAAAAGTTCTTTACAGACCGTAAATAAAATGAGAACAAATAGGCAACATACGAGAGG
CGGAGGCAAGATGTTTACTC

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 695

Protein sequence:

>696_residues
MSGRPEALFGLFSSLETLDGVGPKTAANFAGLGVHAPRDLLFTLPINVLDRRHRNTIEGLDCPTITTVAVTIGAHRPPRT
KGAAYRISVVDAEAAFQLVFFHARGDYLARILPQGSRRVVSGKLERFDGVYQMVHPDYILSETEVDTIPPFEPVYPLTSG
ITQKVMFKATRAALKLLPDLTEWIDPGQIRKAGWPDVREAFTLAHRPQAPQDISITAAARERLAYDEMFAHQMTLALARL
TERQKKGRATHGTGDLQMRLIESLPYPLTGAQQRAIADVNRDMAEAVRMNRLLQGDVGAGKTLVAFLALLRAVEGGGQGV
LMAPTEILARQHLQSLKPMAEHVGVRLDILTGRDTGKERTAKLEDLANGNIGVLVGTHAVFQKGVTFSDLRLAVIDEQHR
FGVQQRMALGQKGAAVDVLVMTATPIPRSLALAQFGDMDVSVLDEKPPGRMPIKTALVSVDRMEEVVSRLCAVVEGGRQC
YWVCPLVEESEVVDLTAAEDRFKKLRAALGEGVVGLVHGQMPAAEKDAAMAGFESGQTKVLVATTVIEVGVNVPNATIMV
IERAEFFGLAQLHQLRGRVGRGTAASTCLLLYQPPLSESGQRRLEVLRETEDGFMIAETDLKMRGAGDVIGTAQSGLPRF
WIADLERQAGLMQIAQSDARKLLADDPGLATPRGQAARMLLWLLRKDESIRLITVG

Sequences:

>Translated_696_residues
MSGRPEALFGLFSSLETLDGVGPKTAANFAGLGVHAPRDLLFTLPINVLDRRHRNTIEGLDCPTITTVAVTIGAHRPPRT
KGAAYRISVVDAEAAFQLVFFHARGDYLARILPQGSRRVVSGKLERFDGVYQMVHPDYILSETEVDTIPPFEPVYPLTSG
ITQKVMFKATRAALKLLPDLTEWIDPGQIRKAGWPDVREAFTLAHRPQAPQDISITAAARERLAYDEMFAHQMTLALARL
TERQKKGRATHGTGDLQMRLIESLPYPLTGAQQRAIADVNRDMAEAVRMNRLLQGDVGAGKTLVAFLALLRAVEGGGQGV
LMAPTEILARQHLQSLKPMAEHVGVRLDILTGRDTGKERTAKLEDLANGNIGVLVGTHAVFQKGVTFSDLRLAVIDEQHR
FGVQQRMALGQKGAAVDVLVMTATPIPRSLALAQFGDMDVSVLDEKPPGRMPIKTALVSVDRMEEVVSRLCAVVEGGRQC
YWVCPLVEESEVVDLTAAEDRFKKLRAALGEGVVGLVHGQMPAAEKDAAMAGFESGQTKVLVATTVIEVGVNVPNATIMV
IERAEFFGLAQLHQLRGRVGRGTAASTCLLLYQPPLSESGQRRLEVLRETEDGFMIAETDLKMRGAGDVIGTAQSGLPRF
WIADLERQAGLMQIAQSDARKLLADDPGLATPRGQAARMLLWLLRKDESIRLITVG
>Mature_695_residues
SGRPEALFGLFSSLETLDGVGPKTAANFAGLGVHAPRDLLFTLPINVLDRRHRNTIEGLDCPTITTVAVTIGAHRPPRTK
GAAYRISVVDAEAAFQLVFFHARGDYLARILPQGSRRVVSGKLERFDGVYQMVHPDYILSETEVDTIPPFEPVYPLTSGI
TQKVMFKATRAALKLLPDLTEWIDPGQIRKAGWPDVREAFTLAHRPQAPQDISITAAARERLAYDEMFAHQMTLALARLT
ERQKKGRATHGTGDLQMRLIESLPYPLTGAQQRAIADVNRDMAEAVRMNRLLQGDVGAGKTLVAFLALLRAVEGGGQGVL
MAPTEILARQHLQSLKPMAEHVGVRLDILTGRDTGKERTAKLEDLANGNIGVLVGTHAVFQKGVTFSDLRLAVIDEQHRF
GVQQRMALGQKGAAVDVLVMTATPIPRSLALAQFGDMDVSVLDEKPPGRMPIKTALVSVDRMEEVVSRLCAVVEGGRQCY
WVCPLVEESEVVDLTAAEDRFKKLRAALGEGVVGLVHGQMPAAEKDAAMAGFESGQTKVLVATTVIEVGVNVPNATIMVI
ERAEFFGLAQLHQLRGRVGRGTAASTCLLLYQPPLSESGQRRLEVLRETEDGFMIAETDLKMRGAGDVIGTAQSGLPRFW
IADLERQAGLMQIAQSDARKLLADDPGLATPRGQAARMLLWLLRKDESIRLITVG

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=675, Percent_Identity=41.3333333333333, Blast_Score=453, Evalue=1e-128,
Organism=Escherichia coli, GI1787357, Length=397, Percent_Identity=37.7833753148615, Blast_Score=256, Evalue=4e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 75786; Mature: 75655

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRPEALFGLFSSLETLDGVGPKTAANFAGLGVHAPRDLLFTLPINVLDRRHRNTIEGL
CCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCEEEECCHHHHHHHHCCCCCCC
DCPTITTVAVTIGAHRPPRTKGAAYRISVVDAEAAFQLVFFHARGDYLARILPQGSRRVV
CCCCCEEEEEEECCCCCCCCCCCEEEEEEEEHHHEEEEEEEECCCCHHHHHCCCCCCCHH
SGKLERFDGVYQMVHPDYILSETEVDTIPPFEPVYPLTSGITQKVMFKATRAALKLLPDL
HHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TEWIDPGQIRKAGWPDVREAFTLAHRPQAPQDISITAAARERLAYDEMFAHQMTLALARL
HHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
TERQKKGRATHGTGDLQMRLIESLPYPLTGAQQRAIADVNRDMAEAVRMNRLLQGDVGAG
HHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KTLVAFLALLRAVEGGGQGVLMAPTEILARQHLQSLKPMAEHVGVRLDILTGRDTGKERT
HHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHH
AKLEDLANGNIGVLVGTHAVFQKGVTFSDLRLAVIDEQHRFGVQQRMALGQKGAAVDVLV
HHHHHHCCCCEEEEECCHHHHHCCCCHHHEEEEEECCHHHHCHHHHHHHCCCCCEEEEEE
MTATPIPRSLALAQFGDMDVSVLDEKPPGRMPIKTALVSVDRMEEVVSRLCAVVEGGRQC
EECCCCCHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEE
YWVCPLVEESEVVDLTAAEDRFKKLRAALGEGVVGLVHGQMPAAEKDAAMAGFESGQTKV
EEEECCCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCCEEE
LVATTVIEVGVNVPNATIMVIERAEFFGLAQLHQLRGRVGRGTAASTCLLLYQPPLSESG
EEEEEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCHHEEEEEECCCCCCCH
QRRLEVLRETEDGFMIAETDLKMRGAGDVIGTAQSGLPRFWIADLERQAGLMQIAQSDAR
HHHHHHHHCCCCCEEEEECCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KLLADDPGLATPRGQAARMLLWLLRKDESIRLITVG
HHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
>Mature Secondary Structure 
SGRPEALFGLFSSLETLDGVGPKTAANFAGLGVHAPRDLLFTLPINVLDRRHRNTIEGL
CCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCEEEECCHHHHHHHHCCCCCCC
DCPTITTVAVTIGAHRPPRTKGAAYRISVVDAEAAFQLVFFHARGDYLARILPQGSRRVV
CCCCCEEEEEEECCCCCCCCCCCEEEEEEEEHHHEEEEEEEECCCCHHHHHCCCCCCCHH
SGKLERFDGVYQMVHPDYILSETEVDTIPPFEPVYPLTSGITQKVMFKATRAALKLLPDL
HHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TEWIDPGQIRKAGWPDVREAFTLAHRPQAPQDISITAAARERLAYDEMFAHQMTLALARL
HHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
TERQKKGRATHGTGDLQMRLIESLPYPLTGAQQRAIADVNRDMAEAVRMNRLLQGDVGAG
HHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KTLVAFLALLRAVEGGGQGVLMAPTEILARQHLQSLKPMAEHVGVRLDILTGRDTGKERT
HHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHH
AKLEDLANGNIGVLVGTHAVFQKGVTFSDLRLAVIDEQHRFGVQQRMALGQKGAAVDVLV
HHHHHHCCCCEEEEECCHHHHHCCCCHHHEEEEEECCHHHHCHHHHHHHCCCCCEEEEEE
MTATPIPRSLALAQFGDMDVSVLDEKPPGRMPIKTALVSVDRMEEVVSRLCAVVEGGRQC
EECCCCCHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEE
YWVCPLVEESEVVDLTAAEDRFKKLRAALGEGVVGLVHGQMPAAEKDAAMAGFESGQTKV
EEEECCCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCCEEE
LVATTVIEVGVNVPNATIMVIERAEFFGLAQLHQLRGRVGRGTAASTCLLLYQPPLSESG
EEEEEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCHHEEEEEECCCCCCCH
QRRLEVLRETEDGFMIAETDLKMRGAGDVIGTAQSGLPRFWIADLERQAGLMQIAQSDAR
HHHHHHHHCCCCCEEEEECCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KLLADDPGLATPRGQAARMLLWLLRKDESIRLITVG
HHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]