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The map label for this gene is htrB [C]

Identifier: 110679793

GI number: 110679793

Start: 2445230

End: 2446132

Strand: Reverse

Name: htrB [C]

Synonym: RD1_2557

Alternate gene names: 110679793

Gene position: 2446132-2445230 (Counterclockwise)

Preceding gene: 110679794

Following gene: 110679791

Centisome position: 59.18

GC content: 59.03

Gene sequence:

>903_bases
ATGCCGAAAGCGCCGCCGAGTAACGTCGACCGTGTGATTCAATACGCGACGAACCTCATTGTTACTCTTGTGATCCGCAT
CGCTCTTGCCTTGCCATATAAGTTCCGCGTCAGAATGGTCGGGCGGCTGATGCAACATGTCATTGGCCCGATTGCCGGGT
ATCGCCAGCGCGCCCTTTCAAACCTCGAACTGATCTGGCCTGACCGCCCCCTGAAAGAGCGCAAACAGATTGCATCCGGG
TGCATGAACAACATGGGCCGCACACTGATCGAGAATTACTCCCGGCATGACTTCCCTGCCCGGCTGGCCAACAACCCGCT
GACGGGGGCCGGTGTCGCCGCGTGGGAAGAGGCGGTCGCACAGAACCGGCCCGTGATTTTGGTGACAGGGCACTACGGCA
ATTATGAAGCCGTGCGCGCCGCGCTCGCCGGGCGCGGCCACGCGGTTGGTGGTCTTTATCGCAATATGACGAACCCGTAT
TTCAACGCACACTACGTCAAGACGATGCAGACCTTTGGCGGACCTGTGTTCGCGCAAGGGCGCAAAGGGACAAAAGGCTT
TGTGCGCCACCTGAAACAGGGCGGTCAGCTGGTGCTGCTGTTTGATCAGCACGTCAGATGGGCGCCGAAAATGAATTTTC
TGGGCCGCCCTGCCCATACCGCCACCTCGGCAGCGGAGTTAAGTCTGCGCTATGACGCGCTGCTTTTGCCCTTTTACGGT
ATCAGGCAGCCGGATGGATTGAGCTTTGAAACAGTTCTTGAGGCTCCGATTTCCCCGTCAACACCCGAGCGAATGACCCA
GGACATCACCGATACGCTCACTCGACGGATCGAACAGGACCCGAGCCAGTGGTTTTGGGTGCATCGCCGGTGGCGCGCCA
AGGTCGGCAAGGTCAGACGGTAA

Upstream 100 bases:

>100_bases
TACCTAAGCCTTGAGGTCATGGCGAGACGGCGTTATTTGTCTCGGGTACTGCGGTTGCTTTCCAAAAGCCACCCGCTGAC
CAAAAGGGTGCACTGCCACT

Downstream 100 bases:

>100_bases
GCGCCCTACTCTGCCCGCGCCGCCGCAAGGATCGGCCCGTGCGTGCCCGACTGAATAAGCACAACCACCGGATGCACCCC
CGGCGCATCGGCATCAATAC

Product: lipid A biosynthesis lauroyl acyltransferase, putative

Products: KDO2-(lauroyl)-lipid IVA [C]

Alternate protein names: Lipid A Biosynthesis Lauroyl Acyltransferase; Acyltransferase HtrB Family; Bacterial Lipid A Biosynthesis Acyltransferase Superfamily; Acyltransferase; Lauroyl/Myristoyl Acyltransferase; Lipid A Biosynthesis Lauroyl/Myristoyl Acyltransferase; Bacterial Lipid A Biosynthesis Acyltransferase; Lipid A Lauroyl Acyltransferase Protein

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MPKAPPSNVDRVIQYATNLIVTLVIRIALALPYKFRVRMVGRLMQHVIGPIAGYRQRALSNLELIWPDRPLKERKQIASG
CMNNMGRTLIENYSRHDFPARLANNPLTGAGVAAWEEAVAQNRPVILVTGHYGNYEAVRAALAGRGHAVGGLYRNMTNPY
FNAHYVKTMQTFGGPVFAQGRKGTKGFVRHLKQGGQLVLLFDQHVRWAPKMNFLGRPAHTATSAAELSLRYDALLLPFYG
IRQPDGLSFETVLEAPISPSTPERMTQDITDTLTRRIEQDPSQWFWVHRRWRAKVGKVRR

Sequences:

>Translated_300_residues
MPKAPPSNVDRVIQYATNLIVTLVIRIALALPYKFRVRMVGRLMQHVIGPIAGYRQRALSNLELIWPDRPLKERKQIASG
CMNNMGRTLIENYSRHDFPARLANNPLTGAGVAAWEEAVAQNRPVILVTGHYGNYEAVRAALAGRGHAVGGLYRNMTNPY
FNAHYVKTMQTFGGPVFAQGRKGTKGFVRHLKQGGQLVLLFDQHVRWAPKMNFLGRPAHTATSAAELSLRYDALLLPFYG
IRQPDGLSFETVLEAPISPSTPERMTQDITDTLTRRIEQDPSQWFWVHRRWRAKVGKVRR
>Mature_299_residues
PKAPPSNVDRVIQYATNLIVTLVIRIALALPYKFRVRMVGRLMQHVIGPIAGYRQRALSNLELIWPDRPLKERKQIASGC
MNNMGRTLIENYSRHDFPARLANNPLTGAGVAAWEEAVAQNRPVILVTGHYGNYEAVRAALAGRGHAVGGLYRNMTNPYF
NAHYVKTMQTFGGPVFAQGRKGTKGFVRHLKQGGQLVLLFDQHVRWAPKMNFLGRPAHTATSAAELSLRYDALLLPFYGI
RQPDGLSFETVLEAPISPSTPERMTQDITDTLTRRIEQDPSQWFWVHRRWRAKVGKVRR

Specific function: Acylates The Intermediate (Kdo)2-Lipid IVa To Form (Kdo)2-(Lauroyl)-Lipid IVa. Has 10 Fold Selectivity For Lauroyl- Acp Over Myristoyl-Acp. [C]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787292, Length=282, Percent_Identity=24.822695035461, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.- [C]

Molecular weight: Translated: 33907; Mature: 33776

Theoretical pI: Translated: 11.15; Mature: 11.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKAPPSNVDRVIQYATNLIVTLVIRIALALPYKFRVRMVGRLMQHVIGPIAGYRQRALS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NLELIWPDRPLKERKQIASGCMNNMGRTLIENYSRHDFPARLANNPLTGAGVAAWEEAVA
CCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCHHHHHHHHHH
QNRPVILVTGHYGNYEAVRAALAGRGHAVGGLYRNMTNPYFNAHYVKTMQTFGGPVFAQG
CCCCEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEECC
RKGTKGFVRHLKQGGQLVLLFDQHVRWAPKMNFLGRPAHTATSAAELSLRYDALLLPFYG
CCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHC
IRQPDGLSFETVLEAPISPSTPERMTQDITDTLTRRIEQDPSQWFWVHRRWRAKVGKVRR
CCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PKAPPSNVDRVIQYATNLIVTLVIRIALALPYKFRVRMVGRLMQHVIGPIAGYRQRALS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NLELIWPDRPLKERKQIASGCMNNMGRTLIENYSRHDFPARLANNPLTGAGVAAWEEAVA
CCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCHHHHHHHHHH
QNRPVILVTGHYGNYEAVRAALAGRGHAVGGLYRNMTNPYFNAHYVKTMQTFGGPVFAQG
CCCCEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEECC
RKGTKGFVRHLKQGGQLVLLFDQHVRWAPKMNFLGRPAHTATSAAELSLRYDALLLPFYG
CCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHC
IRQPDGLSFETVLEAPISPSTPERMTQDITDTLTRRIEQDPSQWFWVHRRWRAKVGKVRR
CCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: KDO2-lipid IVA; lauroyl-ACP [C]

Specific reaction: KDO2-lipid IVA + lauroyl-ACP = KDO2-(lauroyl)-lipid IVA + [acyl carrier protein] [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA