| Definition | Roseobacter denitrificans OCh 114, complete genome. |
|---|---|
| Accession | NC_008209 |
| Length | 4,133,097 |
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The map label for this gene is yusZ [H]
Identifier: 110679741
GI number: 110679741
Start: 2387762
End: 2388646
Strand: Direct
Name: yusZ [H]
Synonym: RD1_2502
Alternate gene names: 110679741
Gene position: 2387762-2388646 (Clockwise)
Preceding gene: 110679740
Following gene: 110679742
Centisome position: 57.77
GC content: 60.0
Gene sequence:
>885_bases ATGACAGATACAAAAACAATTCTCATTACCGGCGCAAGCCGCGGTATTGGCCATCTTGCATCGCTGGCGCTGGCTGCACA CGGCCATAGGGTCTATGCCGGAATGCGCGACATTGCAGGAAGCAACAAGGACGCGGCCTCCGCCATGCAGGCACAGGCAC AGGCGGAGAGGCTCAACCTTGTCCCGCTTGAACTGGACGTTACAAACGCGCAAGCCTGCCAAACAGCCATCGACAAGATC GAGGCAGATGGCCCTCTTGATGTGCTGGTCAACAACGCCGGGGTGATGCCTGTCGGTCTGACCGAGGCATTCACGATGGA GCAGGCAAAGGATGTTTTCGACGTGAACGTCTATGGCATCATGCGTTTGACGCGGGCCGCGCTGCCCTGCATGCGGGCCC GGAAATCCGGTCTGGTGATCAACCTCAGTTCTTCCGCGGGGCGTTTCGGGATGCCCTATTTCGGTATCTACTGCGCCAGC AAGTGGGCGGTTGAGGCTTACAGCGAAGCGCTCCACCACGAGCTTGAGACCTTTGGGATCACCTGCGTTTTGATCGAGCC AAGCGGGCATGGCACAGATCTGGTCACGACAGCACCCGCGCCGCAGGACACGGCGCGTCTGGAGGCCTATGGCGATCTTG CGGCAGGTCGGGAACGCCTTCTGGACATGTTCGGGCATATGTTCGCAACGGACCTCATTGGGACCGATGCCAATAACGTG GCGACAGCAATCGCGCAGCTGATCGAGATGCCGGGAGCGCGGCCAATGCGCGTGCAAGTGGGGCACGACATGGGAGTAAG CGCGGTGAATGAGGCTGTCGCGCCCCTTCAGGCAAAACTGATCGAGACGTTGAAACCGGTCTATCGCGGCGCGCGCCAAG CATGA
Upstream 100 bases:
>100_bases GGGCCGCGAAGCGATCTTCGACGCCATCGTGCCGACACGGCCATGATGGCGGGAAAACGCGCGTATCCCTTCAATCAAAC ACCCTTCAACGAGGTCAGAC
Downstream 100 bases:
>100_bases TATCGGCTTCCTGCGAGGCTTTGACGCGGAGGTTGTTTTGGCTTGGCCGAATGATAAGCAGCTTGCCGATCCGGATGTCC TGCACCGTAGTGTCCGCGGC
Product: oxidoreductase, putative
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: ORFA [H]
Number of amino acids: Translated: 294; Mature: 293
Protein sequence:
>294_residues MTDTKTILITGASRGIGHLASLALAAHGHRVYAGMRDIAGSNKDAASAMQAQAQAERLNLVPLELDVTNAQACQTAIDKI EADGPLDVLVNNAGVMPVGLTEAFTMEQAKDVFDVNVYGIMRLTRAALPCMRARKSGLVINLSSSAGRFGMPYFGIYCAS KWAVEAYSEALHHELETFGITCVLIEPSGHGTDLVTTAPAPQDTARLEAYGDLAAGRERLLDMFGHMFATDLIGTDANNV ATAIAQLIEMPGARPMRVQVGHDMGVSAVNEAVAPLQAKLIETLKPVYRGARQA
Sequences:
>Translated_294_residues MTDTKTILITGASRGIGHLASLALAAHGHRVYAGMRDIAGSNKDAASAMQAQAQAERLNLVPLELDVTNAQACQTAIDKI EADGPLDVLVNNAGVMPVGLTEAFTMEQAKDVFDVNVYGIMRLTRAALPCMRARKSGLVINLSSSAGRFGMPYFGIYCAS KWAVEAYSEALHHELETFGITCVLIEPSGHGTDLVTTAPAPQDTARLEAYGDLAAGRERLLDMFGHMFATDLIGTDANNV ATAIAQLIEMPGARPMRVQVGHDMGVSAVNEAVAPLQAKLIETLKPVYRGARQA >Mature_293_residues TDTKTILITGASRGIGHLASLALAAHGHRVYAGMRDIAGSNKDAASAMQAQAQAERLNLVPLELDVTNAQACQTAIDKIE ADGPLDVLVNNAGVMPVGLTEAFTMEQAKDVFDVNVYGIMRLTRAALPCMRARKSGLVINLSSSAGRFGMPYFGIYCASK WAVEAYSEALHHELETFGITCVLIEPSGHGTDLVTTAPAPQDTARLEAYGDLAAGRERLLDMFGHMFATDLIGTDANNVA TAIAQLIEMPGARPMRVQVGHDMGVSAVNEAVAPLQAKLIETLKPVYRGARQA
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7657478, Length=262, Percent_Identity=32.0610687022901, Blast_Score=108, Evalue=7e-24, Organism=Homo sapiens, GI223718074, Length=185, Percent_Identity=37.2972972972973, Blast_Score=103, Evalue=3e-22, Organism=Homo sapiens, GI19743808, Length=187, Percent_Identity=34.7593582887701, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI22507405, Length=196, Percent_Identity=36.2244897959184, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI150247226, Length=197, Percent_Identity=36.0406091370558, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI44680136, Length=189, Percent_Identity=31.7460317460317, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI44680133, Length=189, Percent_Identity=31.7460317460317, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI17738292, Length=189, Percent_Identity=31.7460317460317, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI40548397, Length=196, Percent_Identity=33.1632653061224, Blast_Score=86, Evalue=5e-17, Organism=Homo sapiens, GI214010158, Length=196, Percent_Identity=33.1632653061224, Blast_Score=86, Evalue=5e-17, Organism=Homo sapiens, GI214010156, Length=196, Percent_Identity=33.1632653061224, Blast_Score=86, Evalue=5e-17, Organism=Homo sapiens, GI22758144, Length=196, Percent_Identity=33.1632653061224, Blast_Score=86, Evalue=5e-17, Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=28.7179487179487, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI4504503, Length=201, Percent_Identity=30.8457711442786, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI142976729, Length=178, Percent_Identity=30.3370786516854, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI210032110, Length=177, Percent_Identity=29.3785310734463, Blast_Score=75, Evalue=1e-13, Organism=Homo sapiens, GI157739938, Length=193, Percent_Identity=26.9430051813472, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI7706318, Length=208, Percent_Identity=26.9230769230769, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI50726952, Length=185, Percent_Identity=35.1351351351351, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI4503817, Length=187, Percent_Identity=25.1336898395722, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI109715829, Length=173, Percent_Identity=30.635838150289, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI7705855, Length=211, Percent_Identity=25.1184834123223, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI40807363, Length=189, Percent_Identity=29.1005291005291, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI4557649, Length=169, Percent_Identity=28.4023668639053, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI210032112, Length=107, Percent_Identity=35.5140186915888, Blast_Score=66, Evalue=4e-11, Organism=Escherichia coli, GI1787335, Length=218, Percent_Identity=31.1926605504587, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1786701, Length=232, Percent_Identity=30.6034482758621, Blast_Score=88, Evalue=8e-19, Organism=Escherichia coli, GI1790717, Length=191, Percent_Identity=31.9371727748691, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=31.1827956989247, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1786812, Length=213, Percent_Identity=27.2300469483568, Blast_Score=74, Evalue=8e-15, Organism=Escherichia coli, GI2367175, Length=211, Percent_Identity=32.2274881516588, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1787526, Length=219, Percent_Identity=28.7671232876712, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI87082160, Length=205, Percent_Identity=26.3414634146341, Blast_Score=67, Evalue=2e-12, Organism=Escherichia coli, GI87082100, Length=185, Percent_Identity=30.2702702702703, Blast_Score=65, Evalue=5e-12, Organism=Caenorhabditis elegans, GI71994604, Length=204, Percent_Identity=31.3725490196078, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI115534660, Length=195, Percent_Identity=29.7435897435897, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI193210355, Length=235, Percent_Identity=28.5106382978723, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17544670, Length=218, Percent_Identity=30.2752293577982, Blast_Score=79, Evalue=4e-15, Organism=Caenorhabditis elegans, GI32563809, Length=209, Percent_Identity=27.7511961722488, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17507613, Length=209, Percent_Identity=27.7511961722488, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17557780, Length=202, Percent_Identity=27.7227722772277, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI71994600, Length=176, Percent_Identity=30.1136363636364, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17560176, Length=195, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17562904, Length=222, Percent_Identity=26.5765765765766, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI115534694, Length=191, Percent_Identity=28.7958115183246, Blast_Score=64, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17558628, Length=190, Percent_Identity=29.4736842105263, Blast_Score=64, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17508895, Length=189, Percent_Identity=28.042328042328, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=190, Percent_Identity=35.2631578947368, Blast_Score=97, Evalue=3e-21, Organism=Saccharomyces cerevisiae, GI6322067, Length=206, Percent_Identity=30.0970873786408, Blast_Score=79, Evalue=1e-15, Organism=Saccharomyces cerevisiae, GI6322861, Length=187, Percent_Identity=30.4812834224599, Blast_Score=75, Evalue=1e-14, Organism=Drosophila melanogaster, GI281364892, Length=175, Percent_Identity=37.1428571428571, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI21355631, Length=173, Percent_Identity=29.4797687861272, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24651139, Length=231, Percent_Identity=29.4372294372294, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI28571526, Length=197, Percent_Identity=33.502538071066, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI24644339, Length=192, Percent_Identity=30.2083333333333, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI281364494, Length=182, Percent_Identity=31.8681318681319, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI21356301, Length=193, Percent_Identity=26.9430051813472, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI21357041, Length=188, Percent_Identity=31.3829787234043, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24643142, Length=184, Percent_Identity=29.8913043478261, Blast_Score=69, Evalue=5e-12, Organism=Drosophila melanogaster, GI24640492, Length=172, Percent_Identity=29.0697674418605, Blast_Score=68, Evalue=8e-12, Organism=Drosophila melanogaster, GI21358495, Length=202, Percent_Identity=29.7029702970297, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI116007236, Length=200, Percent_Identity=27, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24639444, Length=219, Percent_Identity=30.1369863013699, Blast_Score=65, Evalue=6e-11, Organism=Drosophila melanogaster, GI23397609, Length=187, Percent_Identity=32.620320855615, Blast_Score=65, Evalue=7e-11, Organism=Drosophila melanogaster, GI24641232, Length=221, Percent_Identity=30.316742081448, Blast_Score=64, Evalue=9e-11, Organism=Drosophila melanogaster, GI116007238, Length=181, Percent_Identity=27.0718232044199, Blast_Score=64, Evalue=1e-10,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 31220; Mature: 31089
Theoretical pI: Translated: 5.84; Mature: 5.84
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 4.4 %Met (Translated Protein) 5.8 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 4.1 %Met (Mature Protein) 5.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTDTKTILITGASRGIGHLASLALAAHGHRVYAGMRDIAGSNKDAASAMQAQAQAERLNL CCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCE VPLELDVTNAQACQTAIDKIEADGPLDVLVNNAGVMPVGLTEAFTMEQAKDVFDVNVYGI EEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCEECCHHHHHHHHHHHHHCCHHHHH MRLTRAALPCMRARKSGLVINLSSSAGRFGMPYFGIYCASKWAVEAYSEALHHELETFGI HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCE TCVLIEPSGHGTDLVTTAPAPQDTARLEAYGDLAAGRERLLDMFGHMFATDLIGTDANNV EEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH ATAIAQLIEMPGARPMRVQVGHDMGVSAVNEAVAPLQAKLIETLKPVYRGARQA HHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC >Mature Secondary Structure TDTKTILITGASRGIGHLASLALAAHGHRVYAGMRDIAGSNKDAASAMQAQAQAERLNL CCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCE VPLELDVTNAQACQTAIDKIEADGPLDVLVNNAGVMPVGLTEAFTMEQAKDVFDVNVYGI EEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCEECCHHHHHHHHHHHHHCCHHHHH MRLTRAALPCMRARKSGLVINLSSSAGRFGMPYFGIYCASKWAVEAYSEALHHELETFGI HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCE TCVLIEPSGHGTDLVTTAPAPQDTARLEAYGDLAAGRERLLDMFGHMFATDLIGTDANNV EEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH ATAIAQLIEMPGARPMRVQVGHDMGVSAVNEAVAPLQAKLIETLKPVYRGARQA HHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9353931; 9384377; 8396117 [H]