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The map label for this gene is glmS [H]

Identifier: 110679666

GI number: 110679666

Start: 2306638

End: 2307804

Strand: Direct

Name: glmS [H]

Synonym: RD1_2418

Alternate gene names: 110679666

Gene position: 2306638-2307804 (Clockwise)

Preceding gene: 110679648

Following gene: 110679667

Centisome position: 55.81

GC content: 62.13

Gene sequence:

>1167_bases
GTGCCACATTTTTTCGATGCGCTCCTATGCTGGCGGTCAATCACGGAGAGCCCAATGAGTATCGAGCAAAGACTGAAAGA
AATCCGGCGCGAGTCGTCTTCGGATGCGGCTGGCGATCCGGAACGGTTTCGCCGTGTCGCGTTGACCGAATATGAGATGA
TGTCGCAAGGGGAGGCGATCAGCGCCACGCTTGAGGCAAACAGGGGCCCGCTAACGGATATCGGGCGCGATCTTGCGGGG
CGGACGATCCGTCGCGTGGTCACGGTCGGATGCGGCGACAGCTGGATCGCAGGTCACGGTGTGCGACCCGCCATCGAGGC
GGCGCTCGGCGCGCCCTGCGAGCCTGTGGAAGCGTTTGATTTCGCCACGTACGGCTTGCACACGATTGATGCGGAAACCG
TGGTGATCGGGCTGAGCTCTTCTGGAAAGACCGAGCCGGTGGTCGAAGGATTGACCGCGTCGGCTGCGCGGGGGGCATAT
ACGATTGGTCTGTCCAACACGCTTGGGTCCCCGTTGATGGAACAATGCCCGGGTGCGCTGCATATTCGCGCGACACGGGG
CGGTTGGCCCACGCAATCGAGCACGGCTGCGATGGCCCTGATGCTCGCGATGGCGGCGTCGGTGCAAAAGGCGAAAGGTG
GAGACAGCAGCGCGCTTGAAGCTGCCCTCGATGCGCTGCCGGGTCAGGTGGATGACGTGGCGCAGGCTTTTTACGAGCCT
GCCAAAGCAGTGGCAAAGCACCTTGCCCGCGCCGATCTTATTCTGACGACGGGGGCGGGTCCTTTCTTTGCCCCGGCAGA
GTTCGGCGCGGCCAAGTTGAAGGAACTGGCCCCCATTCATGCCTATTCCTTTCCGCTGGAAGAGTATCACCATTACCGCA
CACAGAAAGCGGGCGATCCGATGTTCATGGTCGCGGGTGACGCAGAAAGCCACGCCCGTGCGCTGGAAACCGCGATCATG
TCGCGGGGCTGTGAGGGCTATTGCGTGGCGTTGGTCCCCGAGGGTGAGACGGAAATTGCCGAGATCGCTGATGTGGCCTG
GCATCTGCCGTTAGTGCCTGCCGAGACCGCACCGATTATCTACAGCGTGCCTTTGCACCTCTTTGGGTATCACGCCGCGG
TAGAGCGCGATGCGCTTGGCCTTGGTGCGCCGAGGCTTGGTCTGTGA

Upstream 100 bases:

>100_bases
TCTGTGCGTCAAAGGAGCATTATGCAGATTATCCATTCAGATTTACTTTCGAAGACTTGCATTTCATTTCAATATGGCAA
ATATCAAAAAGGCGCGTCGA

Downstream 100 bases:

>100_bases
CGTGACGCCTGATCTGATCACGGTCGGCGGGCTTACGGTGGACAATGTCGTCGCTGCTGACGGCACGGTCGCGTTGGATG
TGGCGGGGGGCAACGGGGCA

Product: glucosamine--fructose-6-phosphate aminotransferase, putative

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MPHFFDALLCWRSITESPMSIEQRLKEIRRESSSDAAGDPERFRRVALTEYEMMSQGEAISATLEANRGPLTDIGRDLAG
RTIRRVVTVGCGDSWIAGHGVRPAIEAALGAPCEPVEAFDFATYGLHTIDAETVVIGLSSSGKTEPVVEGLTASAARGAY
TIGLSNTLGSPLMEQCPGALHIRATRGGWPTQSSTAAMALMLAMAASVQKAKGGDSSALEAALDALPGQVDDVAQAFYEP
AKAVAKHLARADLILTTGAGPFFAPAEFGAAKLKELAPIHAYSFPLEEYHHYRTQKAGDPMFMVAGDAESHARALETAIM
SRGCEGYCVALVPEGETEIAEIADVAWHLPLVPAETAPIIYSVPLHLFGYHAAVERDALGLGAPRLGL

Sequences:

>Translated_388_residues
MPHFFDALLCWRSITESPMSIEQRLKEIRRESSSDAAGDPERFRRVALTEYEMMSQGEAISATLEANRGPLTDIGRDLAG
RTIRRVVTVGCGDSWIAGHGVRPAIEAALGAPCEPVEAFDFATYGLHTIDAETVVIGLSSSGKTEPVVEGLTASAARGAY
TIGLSNTLGSPLMEQCPGALHIRATRGGWPTQSSTAAMALMLAMAASVQKAKGGDSSALEAALDALPGQVDDVAQAFYEP
AKAVAKHLARADLILTTGAGPFFAPAEFGAAKLKELAPIHAYSFPLEEYHHYRTQKAGDPMFMVAGDAESHARALETAIM
SRGCEGYCVALVPEGETEIAEIADVAWHLPLVPAETAPIIYSVPLHLFGYHAAVERDALGLGAPRLGL
>Mature_387_residues
PHFFDALLCWRSITESPMSIEQRLKEIRRESSSDAAGDPERFRRVALTEYEMMSQGEAISATLEANRGPLTDIGRDLAGR
TIRRVVTVGCGDSWIAGHGVRPAIEAALGAPCEPVEAFDFATYGLHTIDAETVVIGLSSSGKTEPVVEGLTASAARGAYT
IGLSNTLGSPLMEQCPGALHIRATRGGWPTQSSTAAMALMLAMAASVQKAKGGDSSALEAALDALPGQVDDVAQAFYEPA
KAVAKHLARADLILTTGAGPFFAPAEFGAAKLKELAPIHAYSFPLEEYHHYRTQKAGDPMFMVAGDAESHARALETAIMS
RGCEGYCVALVPEGETEIAEIADVAWHLPLVPAETAPIIYSVPLHLFGYHAAVERDALGLGAPRLGL

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=350, Percent_Identity=24, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4826742, Length=346, Percent_Identity=24.2774566473988, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1790167, Length=359, Percent_Identity=27.0194986072423, Blast_Score=85, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17532899, Length=327, Percent_Identity=26.605504587156, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17532897, Length=322, Percent_Identity=26.0869565217391, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17539970, Length=363, Percent_Identity=24.5179063360882, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6322745, Length=206, Percent_Identity=27.1844660194175, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21357745, Length=303, Percent_Identity=22.7722772277228, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 41096; Mature: 40965

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHFFDALLCWRSITESPMSIEQRLKEIRRESSSDAAGDPERFRRVALTEYEMMSQGEAI
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
SATLEANRGPLTDIGRDLAGRTIRRVVTVGCGDSWIAGHGVRPAIEAALGAPCEPVEAFD
EEEEECCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHCCCCCCHHHHH
FATYGLHTIDAETVVIGLSSSGKTEPVVEGLTASAARGAYTIGLSNTLGSPLMEQCPGAL
HHHHCEEEECCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCHHCCCHHHHHCCCCE
HIRATRGGWPTQSSTAAMALMLAMAASVQKAKGGDSSALEAALDALPGQVDDVAQAFYEP
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
AKAVAKHLARADLILTTGAGPFFAPAEFGAAKLKELAPIHAYSFPLEEYHHYRTQKAGDP
HHHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHCCCCC
MFMVAGDAESHARALETAIMSRGCEGYCVALVPEGETEIAEIADVAWHLPLVPAETAPII
EEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEE
YSVPLHLFGYHAAVERDALGLGAPRLGL
EECHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PHFFDALLCWRSITESPMSIEQRLKEIRRESSSDAAGDPERFRRVALTEYEMMSQGEAI
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
SATLEANRGPLTDIGRDLAGRTIRRVVTVGCGDSWIAGHGVRPAIEAALGAPCEPVEAFD
EEEEECCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHCCCCCCHHHHH
FATYGLHTIDAETVVIGLSSSGKTEPVVEGLTASAARGAYTIGLSNTLGSPLMEQCPGAL
HHHHCEEEECCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCHHCCCHHHHHCCCCE
HIRATRGGWPTQSSTAAMALMLAMAASVQKAKGGDSSALEAALDALPGQVDDVAQAFYEP
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
AKAVAKHLARADLILTTGAGPFFAPAEFGAAKLKELAPIHAYSFPLEEYHHYRTQKAGDP
HHHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHCCCCC
MFMVAGDAESHARALETAIMSRGCEGYCVALVPEGETEIAEIADVAWHLPLVPAETAPII
EEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEE
YSVPLHLFGYHAAVERDALGLGAPRLGL
EECHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]