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The map label for this gene is mtnA [H]

Identifier: 110679633

GI number: 110679633

Start: 2274533

End: 2275636

Strand: Direct

Name: mtnA [H]

Synonym: RD1_2384

Alternate gene names: 110679633

Gene position: 2274533-2275636 (Clockwise)

Preceding gene: 110679632

Following gene: 110679634

Centisome position: 55.03

GC content: 64.58

Gene sequence:

>1104_bases
ATGAAGATCGACGGCACGCACTACCGATCCTTGTGGTGGAACAGCGAAAACCACGTTCTGGAGATCATCGACCAACGCTG
GTTGCCGCATGAATTTCGCGTCATCCCCGTTGCGACGATGCAGGATTTTGCCGATGCCATCTACCAGATGCGGGTACGTG
GCGCGCCCTTGATCGGGGCCACGGCGGCCTATGGGATGGCATTGGCGATGGCCGAGGATGCATCGGACGCAAATATGGAT
GCGGCATGGGCTTTCCTTGAAAAAACCCGCCCGACCGCGATCAACCTGCGGTGGGCGCTGGATCGGTGCCGCGCGGCATT
GCGCCCCTTGCCGGAAGCTGACCGCGCCGCTGCTGCCCTGACGCTGGCCCATGAGATTGCCGATGAGGACGTGGAGATCA
ACCGCCGCATCGGGGAGCACGGTCTGGCCCTGATCCGCGAGATCGCGGCGCGCAAACCGGCGGGCGAACCGGTGCGCCTG
CTGACGCACTGCAACGCCGGGTGGCTGGCGACCGTCGATTGGGGCACCGCGACCAGTCCGATGTATCACGCGCAGGACGC
GGGCATCCCGCTGCACGTCTGGGTGGATGAGACGCGCCCGCGCAATCAGGGTGCGCTGACCGCGTGGGAGTTGGGCAAGC
ACGGCGTGCCCCACACCTATATCACCGACAATGCGGGCGGGCATCTGATGCAGCATGGCATGGTGGATATGGTCATCACC
GGCACCGACCGCACGACGCGGCGCGGTGATGTGTGCAACAAGATCGGCACCTACCTCAAGGCCCTGGCCGCGCATGATAA
TGGCGTGCCGTTCTACGTCGCACTGCCATCCCCGACCATCGACTGGACGGTGAGCGATGGCGTGGCCGAGATCCCCATCG
AGGAACGTGATGCACAAGAAGTCACCCATGTGCAGGGGCTGACCGACGGTGGTGGACTTGGCACCGTGCAGGTCACGCCG
ACGGGGACGCAAGGAGGCAACCCGGCCTTTGACGTGACGCCGAACCGGTTGGTCACGGGCCTGATCACCGAACGCGGGGT
TTGCGACGCCTCCGAGGCCGGGTTGTCCGACCTCTTCCCCAACTTTGCGAAGGCGGCAGAATAG

Upstream 100 bases:

>100_bases
ACCTCAGCATGGGCGCGGAATTGATCCATATGGCAGACACAATTGCGGATGCGCAGGCGGTTTGCGCGCTCGCGCGGAAC
TTTAACCGAAAGGACGTTCT

Downstream 100 bases:

>100_bases
AAGGTGTCGCTGCCGGCAGGGTCCACGGGCAAGGCGAGAGCTGCCGCGCCGGATCTGGCGCGGTTCCCCGCACGCGAAGA
CGCGCTTTATATTGAGGCCG

Product: methylthioribose-1-phosphate isomerase

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MKIDGTHYRSLWWNSENHVLEIIDQRWLPHEFRVIPVATMQDFADAIYQMRVRGAPLIGATAAYGMALAMAEDASDANMD
AAWAFLEKTRPTAINLRWALDRCRAALRPLPEADRAAAALTLAHEIADEDVEINRRIGEHGLALIREIAARKPAGEPVRL
LTHCNAGWLATVDWGTATSPMYHAQDAGIPLHVWVDETRPRNQGALTAWELGKHGVPHTYITDNAGGHLMQHGMVDMVIT
GTDRTTRRGDVCNKIGTYLKALAAHDNGVPFYVALPSPTIDWTVSDGVAEIPIEERDAQEVTHVQGLTDGGGLGTVQVTP
TGTQGGNPAFDVTPNRLVTGLITERGVCDASEAGLSDLFPNFAKAAE

Sequences:

>Translated_367_residues
MKIDGTHYRSLWWNSENHVLEIIDQRWLPHEFRVIPVATMQDFADAIYQMRVRGAPLIGATAAYGMALAMAEDASDANMD
AAWAFLEKTRPTAINLRWALDRCRAALRPLPEADRAAAALTLAHEIADEDVEINRRIGEHGLALIREIAARKPAGEPVRL
LTHCNAGWLATVDWGTATSPMYHAQDAGIPLHVWVDETRPRNQGALTAWELGKHGVPHTYITDNAGGHLMQHGMVDMVIT
GTDRTTRRGDVCNKIGTYLKALAAHDNGVPFYVALPSPTIDWTVSDGVAEIPIEERDAQEVTHVQGLTDGGGLGTVQVTP
TGTQGGNPAFDVTPNRLVTGLITERGVCDASEAGLSDLFPNFAKAAE
>Mature_367_residues
MKIDGTHYRSLWWNSENHVLEIIDQRWLPHEFRVIPVATMQDFADAIYQMRVRGAPLIGATAAYGMALAMAEDASDANMD
AAWAFLEKTRPTAINLRWALDRCRAALRPLPEADRAAAALTLAHEIADEDVEINRRIGEHGLALIREIAARKPAGEPVRL
LTHCNAGWLATVDWGTATSPMYHAQDAGIPLHVWVDETRPRNQGALTAWELGKHGVPHTYITDNAGGHLMQHGMVDMVIT
GTDRTTRRGDVCNKIGTYLKALAAHDNGVPFYVALPSPTIDWTVSDGVAEIPIEERDAQEVTHVQGLTDGGGLGTVQVTP
TGTQGGNPAFDVTPNRLVTGLITERGVCDASEAGLSDLFPNFAKAAE

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=346, Percent_Identity=38.728323699422, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI23943880, Length=343, Percent_Identity=35.5685131195335, Blast_Score=140, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17557462, Length=356, Percent_Identity=34.8314606741573, Blast_Score=180, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI17557123, Length=269, Percent_Identity=25.2788104089219, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325375, Length=399, Percent_Identity=30.0751879699248, Blast_Score=159, Evalue=9e-40,
Organism=Drosophila melanogaster, GI21357667, Length=352, Percent_Identity=37.5, Blast_Score=191, Evalue=9e-49,
Organism=Drosophila melanogaster, GI24651647, Length=352, Percent_Identity=37.5, Blast_Score=191, Evalue=9e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 39900; Mature: 39900

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIDGTHYRSLWWNSENHVLEIIDQRWLPHEFRVIPVATMQDFADAIYQMRVRGAPLIGA
CCCCCCEEEEEEECCCCHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEECH
TAAYGMALAMAEDASDANMDAAWAFLEKTRPTAINLRWALDRCRAALRPLPEADRAAAAL
HHHHHHHEEEECCCCCCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHH
TLAHEIADEDVEINRRIGEHGLALIREIAARKPAGEPVRLLTHCNAGWLATVDWGTATSP
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCCCCCC
MYHAQDAGIPLHVWVDETRPRNQGALTAWELGKHGVPHTYITDNAGGHLMQHGMVDMVIT
CEECCCCCCEEEEEECCCCCCCCCCEEEEHHCCCCCCCEEEECCCCCHHHHCCCEEEEEE
GTDRTTRRGDVCNKIGTYLKALAAHDNGVPFYVALPSPTIDWTVSDGVAEIPIEERDAQE
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCEEECCCCCCCHHH
VTHVQGLTDGGGLGTVQVTPTGTQGGNPAFDVTPNRLVTGLITERGVCDASEAGLSDLFP
HHHHCCCCCCCCEEEEEEEECCCCCCCCCEECCHHHHHHHHHHCCCCCCCHHCCHHHHCH
NFAKAAE
HHHHHCC
>Mature Secondary Structure
MKIDGTHYRSLWWNSENHVLEIIDQRWLPHEFRVIPVATMQDFADAIYQMRVRGAPLIGA
CCCCCCEEEEEEECCCCHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEECH
TAAYGMALAMAEDASDANMDAAWAFLEKTRPTAINLRWALDRCRAALRPLPEADRAAAAL
HHHHHHHEEEECCCCCCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHH
TLAHEIADEDVEINRRIGEHGLALIREIAARKPAGEPVRLLTHCNAGWLATVDWGTATSP
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCCCCCC
MYHAQDAGIPLHVWVDETRPRNQGALTAWELGKHGVPHTYITDNAGGHLMQHGMVDMVIT
CEECCCCCCEEEEEECCCCCCCCCCEEEEHHCCCCCCCEEEECCCCCHHHHCCCEEEEEE
GTDRTTRRGDVCNKIGTYLKALAAHDNGVPFYVALPSPTIDWTVSDGVAEIPIEERDAQE
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCEEECCCCCCCHHH
VTHVQGLTDGGGLGTVQVTPTGTQGGNPAFDVTPNRLVTGLITERGVCDASEAGLSDLFP
HHHHCCCCCCCCEEEEEEEECCCCCCCCCEECCHHHHHHHHHHCCCCCCCHHCCHHHHCH
NFAKAAE
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA