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The map label for this gene is dppA [H]

Identifier: 110679497

GI number: 110679497

Start: 2128160

End: 2129740

Strand: Reverse

Name: dppA [H]

Synonym: RD1_2226

Alternate gene names: 110679497

Gene position: 2129740-2128160 (Counterclockwise)

Preceding gene: 110679505

Following gene: 110679496

Centisome position: 51.53

GC content: 58.89

Gene sequence:

>1581_bases
ATGAAACCGACAATAGCAACCATGATCGGCGCCTTGCTGCTGACCACTGCCGCACCACTGAGCGCAGAGACACTGCGGTG
GGCGCGCTCCGGCGATGCGCTGACGCTTGATCCGCACGCCCAGAACGAAGGGCCGACCCACACGATCCGCCACCAGATGT
ACGAGCCGCTGATCATCCGCGACGTCACCGGCGCGTTTGAGCCAGCTTTGGCCACGGACTGGGCACCCAAGGCGGATGAT
CCGAATGTCTGGGTGTTCAACCTGCGCGAAGGCGTGAGTTTTCACGATGGCGCGGCCTTTACGGCCGAGGACGTGGTGTT
CAGCTTTGAGCGTGCCAAGCAGCCAAATTCCGACATGAAGGAGTTGATCGGCTCAATCACCGAAGTGCGTGCCGTTGACG
ATTTCACCGTCGAGATCGTGACCGATGGGCCAAACCCGATCTTGCCGTCGAACCTGACCAACCTGTTCATCATGGACAAG
GATTGGACCGAGGCAAACGACACCGTCAATGTGCAGGATTTCGAGGGTGGCGAGATCACTTTTGCGACCACCAACGTCAA
CGGCACCGGGCCCTACGTGCTGACCAGCCGCGAGCCGGACGTGAAAACGGTGATGACGCGCAATGAAGCCTATTGGGGTC
GGGATCAGTTCCCGATGGAAGTGAGCGAAATCATCTATACGCCGATCCAAAATGCAGCGACCCGCGTGGCTGCGATGCTT
TCGGGTGAAATTGATTTCCTGCAGGACATGCCCGTGCAGGACCTCGTGCGCGTGAATGACGTGGATGGGCTGGTGGTCAA
ACAAGCGCCGCAAAACCGGGTCATCTTCTTTGGGATGAACCAGGGCGCGGATGACATCGAAGCGGATAACGTCGACGGTG
CGAACCCGTTGGCCGATGTGCGCGTGCGCAAGGCCATGTCGATGGCGATCAACCGCGATGCGATCCGTCAGGTCGTGATG
CGCGGGCAGAGCCAGCCTGCCGGCATGATCGCCCCCCCCTTCGTGAACGGCTGGACGGCCGAGATGGATGCGGAATCCAC
AACGGATATCGAAGGGGCCAAGGCGCTGATGGCTGAGGCCGGATATGCCGATGGGTTCTCGATCCGGCTGGATTGCCCGA
ACGATCGGTATGTCAATGACGAAGGCATCTGTCAGGCGGCGGTCGGCATGTTGGGTCAGATCGGCGTCACGGTGAACCTT
GATGCCAAACCGAAGGCGCAGCATTTCCCGCTGATCACCGATGGCAAGACTGACTTCTACATGTTGGGCTGGGGCGTGCC
GACGTACGATTCCGAGTACATCTTCAACTTCCTCGTCCACAGCCGCGAATCTGACATCGGCACGTGGAATGGCACCGGAT
TTGGTGATGCCGACCTCGACGCGATGATCAAATCGCTGGCCTCCAACACCGATCTGGAAGCGCGCAACGCCGATATCGCC
AAAATCTGGCGGGTCGTTCAGGATGAGCAACTCTACATCCCAATCCACCATCAGGTGCTGAACTGGGGTATGGCGGAAAA
AGTCGGCATCGAAGTGGATCCCGAAGATCAGCCGAAGGTGAAATACTTCACCATGAACTAA

Upstream 100 bases:

>100_bases
TGGGGATTGAATTAGGGGCCGGATTTCCCGTCAGGCTCTTGCCATTGACAAAAAATAGCCCAAGGTTGCAGCGCAAAAAT
AACAACCACGGGGATTCTGA

Downstream 100 bases:

>100_bases
ACGAGACGCGGTGCGCCCTGCCCTTGGGCGCACCGCTGTTTTCATGCGTCAGCACAGGCCACCGCTTTGGCCCGGTTCAG
GGATAGAATGTTACGTAATT

Product: extracellular solute-binding protein, putative

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MKPTIATMIGALLLTTAAPLSAETLRWARSGDALTLDPHAQNEGPTHTIRHQMYEPLIIRDVTGAFEPALATDWAPKADD
PNVWVFNLREGVSFHDGAAFTAEDVVFSFERAKQPNSDMKELIGSITEVRAVDDFTVEIVTDGPNPILPSNLTNLFIMDK
DWTEANDTVNVQDFEGGEITFATTNVNGTGPYVLTSREPDVKTVMTRNEAYWGRDQFPMEVSEIIYTPIQNAATRVAAML
SGEIDFLQDMPVQDLVRVNDVDGLVVKQAPQNRVIFFGMNQGADDIEADNVDGANPLADVRVRKAMSMAINRDAIRQVVM
RGQSQPAGMIAPPFVNGWTAEMDAESTTDIEGAKALMAEAGYADGFSIRLDCPNDRYVNDEGICQAAVGMLGQIGVTVNL
DAKPKAQHFPLITDGKTDFYMLGWGVPTYDSEYIFNFLVHSRESDIGTWNGTGFGDADLDAMIKSLASNTDLEARNADIA
KIWRVVQDEQLYIPIHHQVLNWGMAEKVGIEVDPEDQPKVKYFTMN

Sequences:

>Translated_526_residues
MKPTIATMIGALLLTTAAPLSAETLRWARSGDALTLDPHAQNEGPTHTIRHQMYEPLIIRDVTGAFEPALATDWAPKADD
PNVWVFNLREGVSFHDGAAFTAEDVVFSFERAKQPNSDMKELIGSITEVRAVDDFTVEIVTDGPNPILPSNLTNLFIMDK
DWTEANDTVNVQDFEGGEITFATTNVNGTGPYVLTSREPDVKTVMTRNEAYWGRDQFPMEVSEIIYTPIQNAATRVAAML
SGEIDFLQDMPVQDLVRVNDVDGLVVKQAPQNRVIFFGMNQGADDIEADNVDGANPLADVRVRKAMSMAINRDAIRQVVM
RGQSQPAGMIAPPFVNGWTAEMDAESTTDIEGAKALMAEAGYADGFSIRLDCPNDRYVNDEGICQAAVGMLGQIGVTVNL
DAKPKAQHFPLITDGKTDFYMLGWGVPTYDSEYIFNFLVHSRESDIGTWNGTGFGDADLDAMIKSLASNTDLEARNADIA
KIWRVVQDEQLYIPIHHQVLNWGMAEKVGIEVDPEDQPKVKYFTMN
>Mature_526_residues
MKPTIATMIGALLLTTAAPLSAETLRWARSGDALTLDPHAQNEGPTHTIRHQMYEPLIIRDVTGAFEPALATDWAPKADD
PNVWVFNLREGVSFHDGAAFTAEDVVFSFERAKQPNSDMKELIGSITEVRAVDDFTVEIVTDGPNPILPSNLTNLFIMDK
DWTEANDTVNVQDFEGGEITFATTNVNGTGPYVLTSREPDVKTVMTRNEAYWGRDQFPMEVSEIIYTPIQNAATRVAAML
SGEIDFLQDMPVQDLVRVNDVDGLVVKQAPQNRVIFFGMNQGADDIEADNVDGANPLADVRVRKAMSMAINRDAIRQVVM
RGQSQPAGMIAPPFVNGWTAEMDAESTTDIEGAKALMAEAGYADGFSIRLDCPNDRYVNDEGICQAAVGMLGQIGVTVNL
DAKPKAQHFPLITDGKTDFYMLGWGVPTYDSEYIFNFLVHSRESDIGTWNGTGFGDADLDAMIKSLASNTDLEARNADIA
KIWRVVQDEQLYIPIHHQVLNWGMAEKVGIEVDPEDQPKVKYFTMN

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=534, Percent_Identity=26.0299625468165, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI87081878, Length=490, Percent_Identity=25.9183673469388, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI1787495, Length=530, Percent_Identity=23.3962264150943, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1789397, Length=530, Percent_Identity=23.7735849056604, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787052, Length=505, Percent_Identity=23.960396039604, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789887, Length=486, Percent_Identity=23.0452674897119, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787762, Length=527, Percent_Identity=22.9601518026565, Blast_Score=96, Evalue=5e-21,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57978; Mature: 57978

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPTIATMIGALLLTTAAPLSAETLRWARSGDALTLDPHAQNEGPTHTIRHQMYEPLIIR
CCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHCCCEEEE
DVTGAFEPALATDWAPKADDPNVWVFNLREGVSFHDGAAFTAEDVVFSFERAKQPNSDMK
ECCCCCCCCHHCCCCCCCCCCCEEEEEECCCCCCCCCCCEEHHHHHHHHHHHCCCCHHHH
ELIGSITEVRAVDDFTVEIVTDGPNPILPSNLTNLFIMDKDWTEANDTVNVQDFEGGEIT
HHHHHHHHHEEECCEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCEEE
FATTNVNGTGPYVLTSREPDVKTVMTRNEAYWGRDQFPMEVSEIIYTPIQNAATRVAAML
EEEECCCCCCCEEEECCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHH
SGEIDFLQDMPVQDLVRVNDVDGLVVKQAPQNRVIFFGMNQGADDIEADNVDGANPLADV
CCCHHHHHCCCHHHHHEECCCCCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHH
RVRKAMSMAINRDAIRQVVMRGQSQPAGMIAPPFVNGWTAEMDAESTTDIEGAKALMAEA
HHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHC
GYADGFSIRLDCPNDRYVNDEGICQAAVGMLGQIGVTVNLDAKPKAQHFPLITDGKTDFY
CCCCCEEEEEECCCCCEECCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCEEECCCCCEE
MLGWGVPTYDSEYIFNFLVHSRESDIGTWNGTGFGDADLDAMIKSLASNTDLEARNADIA
EEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHH
KIWRVVQDEQLYIPIHHQVLNWGMAEKVGIEVDPEDQPKVKYFTMN
HHHHHHCCCEEEEEEHHHHHCCCCHHHCCCEECCCCCCCEEEEECC
>Mature Secondary Structure
MKPTIATMIGALLLTTAAPLSAETLRWARSGDALTLDPHAQNEGPTHTIRHQMYEPLIIR
CCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHCCCEEEE
DVTGAFEPALATDWAPKADDPNVWVFNLREGVSFHDGAAFTAEDVVFSFERAKQPNSDMK
ECCCCCCCCHHCCCCCCCCCCCEEEEEECCCCCCCCCCCEEHHHHHHHHHHHCCCCHHHH
ELIGSITEVRAVDDFTVEIVTDGPNPILPSNLTNLFIMDKDWTEANDTVNVQDFEGGEIT
HHHHHHHHHEEECCEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCEEE
FATTNVNGTGPYVLTSREPDVKTVMTRNEAYWGRDQFPMEVSEIIYTPIQNAATRVAAML
EEEECCCCCCCEEEECCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHH
SGEIDFLQDMPVQDLVRVNDVDGLVVKQAPQNRVIFFGMNQGADDIEADNVDGANPLADV
CCCHHHHHCCCHHHHHEECCCCCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHH
RVRKAMSMAINRDAIRQVVMRGQSQPAGMIAPPFVNGWTAEMDAESTTDIEGAKALMAEA
HHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHC
GYADGFSIRLDCPNDRYVNDEGICQAAVGMLGQIGVTVNLDAKPKAQHFPLITDGKTDFY
CCCCCEEEEEECCCCCEECCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCEEECCCCCEE
MLGWGVPTYDSEYIFNFLVHSRESDIGTWNGTGFGDADLDAMIKSLASNTDLEARNADIA
EEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHH
KIWRVVQDEQLYIPIHHQVLNWGMAEKVGIEVDPEDQPKVKYFTMN
HHHHHHCCCEEEEEEHHHHHCCCCHHHCCCEECCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]