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The map label for this gene is panE

Identifier: 110679471

GI number: 110679471

Start: 2095945

End: 2096922

Strand: Reverse

Name: panE

Synonym: RD1_2198

Alternate gene names: NA

Gene position: 2096922-2095945 (Counterclockwise)

Preceding gene: 110679472

Following gene: 110679470

Centisome position: 50.73

GC content: 61.76

Gene sequence:

>978_bases
ATGAAGATTTGCATATTCGGAGCGGGCGCCATAGGCGGCTATATGGGCGTAAAACTCGCACAGGCTGGCGCGGACGTCAG
TCTCGTCGCGCGGGGCCCACACCTTGCGGCCATGCAGGAAAAGGGCCTGACGCTGATCGAGGAAAGCGGCGAAAGCACCG
TCAAGGTCACCGCCTCTGACAACCCGTCGGACCTTGGGCCGCAGGATTACGTGATCGTCACGCTCAAGGCCCATTCTGTC
CCGCCTGTGGTGGATAAAATGCAGCCGCTGATCGGTGAGAACACGACCATCGTCAGCGGCGTGAACGGCGTGCCGTGGTG
GTATTTCCACAAAATCGGCGGCCCACTGGAAGGCACACGACTCAGCACCGTGGACCCGGGCAATGCACAATGGGACGGGT
TCGGTCCGGACCGCGTGCTCGGCTGCGTGGTCTATCCCGCCGCCGAAGTGTCCGAACCCGGCACGATCAAGCACATCGAG
GGCAACCGCTTTTCCCTCGGCGAACCGGATGGATCAAAGTCCGACCGCGCCTTGGCCTTGTCAAAAGCGCTCGCATCTGC
AGGGCTGAAGGCCCCCGTGCGCCCCCGCCTGCGCGACGAAATCTGGGTCAAGCTATGGGGCAACCTGTCTTTCAACCCGA
TTTCTGCGCTCACCCATGCAACGCTGGATGTGTTGTGCACAGATCCCGGCACCCGTGCCGTTGCGCGCGGCATGATGGTC
GAAGCGCAGGAAATCGCAGAAAAACTTGGCGTGAAATTCCCGATTGATGTGGATCGTCGCATCGACGGGGGGGCGGCTGT
GGGCGCGCATCGCACATCTATGCTGCAAGACCTCGATGCTGGTCGCCCGATGGAAATCGATGCCCTGCTCGGCTCGGTAC
ATGAATTGGGCAAGGTGACGCAGACGCCGACGCCCACGATTGATACGGTGCTTGCGCTGACCAAATTGCGCGCGAAAACG
GCCGGGCTCTACGCCTGA

Upstream 100 bases:

>100_bases
AATGCGCTGATCAGCTTTGCAAAGTTGATCAGCGCAGTTAAGCCCCTGTTATAGCTGCAATACCACCAGCGCGGCTCAGG
GGATTTGAAGGAAAAACACC

Downstream 100 bases:

>100_bases
GGGAGGGTCGCTATGTCCATCAAGAACATTCTTGTCGCCTATAACGGCCTGCCCGGATCCGGTGCGGCCCTGCACGGCGC
GGTCACGATGCAGAAGTTTT

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MKICIFGAGAIGGYMGVKLAQAGADVSLVARGPHLAAMQEKGLTLIEESGESTVKVTASDNPSDLGPQDYVIVTLKAHSV
PPVVDKMQPLIGENTTIVSGVNGVPWWYFHKIGGPLEGTRLSTVDPGNAQWDGFGPDRVLGCVVYPAAEVSEPGTIKHIE
GNRFSLGEPDGSKSDRALALSKALASAGLKAPVRPRLRDEIWVKLWGNLSFNPISALTHATLDVLCTDPGTRAVARGMMV
EAQEIAEKLGVKFPIDVDRRIDGGAAVGAHRTSMLQDLDAGRPMEIDALLGSVHELGKVTQTPTPTIDTVLALTKLRAKT
AGLYA

Sequences:

>Translated_325_residues
MKICIFGAGAIGGYMGVKLAQAGADVSLVARGPHLAAMQEKGLTLIEESGESTVKVTASDNPSDLGPQDYVIVTLKAHSV
PPVVDKMQPLIGENTTIVSGVNGVPWWYFHKIGGPLEGTRLSTVDPGNAQWDGFGPDRVLGCVVYPAAEVSEPGTIKHIE
GNRFSLGEPDGSKSDRALALSKALASAGLKAPVRPRLRDEIWVKLWGNLSFNPISALTHATLDVLCTDPGTRAVARGMMV
EAQEIAEKLGVKFPIDVDRRIDGGAAVGAHRTSMLQDLDAGRPMEIDALLGSVHELGKVTQTPTPTIDTVLALTKLRAKT
AGLYA
>Mature_325_residues
MKICIFGAGAIGGYMGVKLAQAGADVSLVARGPHLAAMQEKGLTLIEESGESTVKVTASDNPSDLGPQDYVIVTLKAHSV
PPVVDKMQPLIGENTTIVSGVNGVPWWYFHKIGGPLEGTRLSTVDPGNAQWDGFGPDRVLGCVVYPAAEVSEPGTIKHIE
GNRFSLGEPDGSKSDRALALSKALASAGLKAPVRPRLRDEIWVKLWGNLSFNPISALTHATLDVLCTDPGTRAVARGMMV
EAQEIAEKLGVKFPIDVDRRIDGGAAVGAHRTSMLQDLDAGRPMEIDALLGSVHELGKVTQTPTPTIDTVLALTKLRAKT
AGLYA

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 34301; Mature: 34301

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKICIFGAGAIGGYMGVKLAQAGADVSLVARGPHLAAMQEKGLTLIEESGESTVKVTASD
CEEEEEECCHHHHHHHHEEECCCCCEEEEECCCCHHHHHHCCCEEEECCCCCEEEEEECC
NPSDLGPQDYVIVTLKAHSVPPVVDKMQPLIGENTTIVSGVNGVPWWYFHKIGGPLEGTR
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCEEEEEECCCCCCCCE
LSTVDPGNAQWDGFGPDRVLGCVVYPAAEVSEPGTIKHIEGNRFSLGEPDGSKSDRALAL
EEEECCCCCCCCCCCHHHEEEEEEECCHHCCCCCCEEEECCCEEECCCCCCCCCCHHHHH
SKALASAGLKAPVRPRLRDEIWVKLWGNLSFNPISALTHATLDVLCTDPGTRAVARGMMV
HHHHHHCCCCCCCCCCHHHEEEEEEECCCCCCHHHHHHHCEEEEEECCCCHHHHHHHHHH
EAQEIAEKLGVKFPIDVDRRIDGGAAVGAHRTSMLQDLDAGRPMEIDALLGSVHELGKVT
HHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCC
QTPTPTIDTVLALTKLRAKTAGLYA
CCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKICIFGAGAIGGYMGVKLAQAGADVSLVARGPHLAAMQEKGLTLIEESGESTVKVTASD
CEEEEEECCHHHHHHHHEEECCCCCEEEEECCCCHHHHHHCCCEEEECCCCCEEEEEECC
NPSDLGPQDYVIVTLKAHSVPPVVDKMQPLIGENTTIVSGVNGVPWWYFHKIGGPLEGTR
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCEEEEEECCCCCCCCE
LSTVDPGNAQWDGFGPDRVLGCVVYPAAEVSEPGTIKHIEGNRFSLGEPDGSKSDRALAL
EEEECCCCCCCCCCCHHHEEEEEEECCHHCCCCCCEEEECCCEEECCCCCCCCCCHHHHH
SKALASAGLKAPVRPRLRDEIWVKLWGNLSFNPISALTHATLDVLCTDPGTRAVARGMMV
HHHHHHCCCCCCCCCCHHHEEEEEEECCCCCCHHHHHHHCEEEEEECCCCHHHHHHHHHH
EAQEIAEKLGVKFPIDVDRRIDGGAAVGAHRTSMLQDLDAGRPMEIDALLGSVHELGKVT
HHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCC
QTPTPTIDTVLALTKLRAKTAGLYA
CCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]