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The map label for this gene is Dml [H]

Identifier: 110679462

GI number: 110679462

Start: 2085574

End: 2086449

Strand: Direct

Name: Dml [H]

Synonym: RD1_2188

Alternate gene names: 110679462

Gene position: 2085574-2086449 (Clockwise)

Preceding gene: 110679461

Following gene: 110679469

Centisome position: 50.46

GC content: 60.84

Gene sequence:

>876_bases
ATGACTGCTGCGAAAACGCTCCGTACCTTGCTGGCGCAGGATAAATGCCATGTGATGCCGTGTTGCTTTGATGCGCTCTC
GGCCAAACTGATCGCGCAGGAGGGGTATGATCTGACCTTCATGTCGGGTTTTGCCGCCTCCGCCAGCCGGATCGGCGCGC
CGGATCTCGGCCTGATGAGCTATGGTGAAGTCGTGGATCAGGCCCGCAACATCGCCACTGCCATCGACATTCCGCTGATC
GGGGATGGCGATACGGGCTATGGCAATGCGATGAATGTGCGCCGCACGGTGACGGGGTTTGCGCAAGCCGGTTGCGCGTC
GGTGATGATCGAAGACCAGCTTGCCCCGAAAAGATGCGGGCACACGCCGGGTAAGGCGGTTGTGCCACGACAAGAGGCAT
ATGACAGGATCAAGGCGGCGGTGGATGCGCGCGATGCCCTGCGCGAAGACGGCGGCGATATCCTGATCCTTGCCCGCACG
GATGCGCGTCATGAACACGGGCTGTCAGAGGCGATCGAACGGGCGGCAGTCTTTGCCGAACTCGGCGCCGATATCCTGTT
CGTGGAGGCTCCTAAATCCATCGCAGAGATGCAGGATATCTGCTCAAACCTGCCCGGTCCCAAGATGGCGAATATCGTCG
AAGGTGGGGAAACACCGGATTTGCCCAATGCGGCCCTGCATGACATCGGCTATTCCATCGCGGCCTATCCGCTGTCTCTG
ATGGCGGCGGCGATGCAGGCGATGGTCACATCGTTGCGCGCGATGCGCGCGGATCAGCGGCCCGGATTGATGGATTTTGG
CGAGTTGCGCAGCCGGATCGGGTTTGACGACTACTATGCGGCGTCGCAAGCCTATGCGTCCTCAAAGCGCGACTGA

Upstream 100 bases:

>100_bases
CGCGGGGTCTGGCCGTTCCTGATGCTGATGCTGTTCACGGTTGGCATTCTTTATCTGGTGCCTGATCTGGCGCTTTATAT
CCCGTTCAAATGGTGAAATC

Downstream 100 bases:

>100_bases
GTATGCGTCGGGGTCGCCGGATGCGTGCTCACAAGTCCTTGACCAGCCTCAGGGCGTCGTAAATCGCCGCATGTGTGTTG
CGGGCCGAAACCGCATCCCC

Product: carboxyvinyl-carboxyphosphonate phosphorylmutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MTAAKTLRTLLAQDKCHVMPCCFDALSAKLIAQEGYDLTFMSGFAASASRIGAPDLGLMSYGEVVDQARNIATAIDIPLI
GDGDTGYGNAMNVRRTVTGFAQAGCASVMIEDQLAPKRCGHTPGKAVVPRQEAYDRIKAAVDARDALREDGGDILILART
DARHEHGLSEAIERAAVFAELGADILFVEAPKSIAEMQDICSNLPGPKMANIVEGGETPDLPNAALHDIGYSIAAYPLSL
MAAAMQAMVTSLRAMRADQRPGLMDFGELRSRIGFDDYYAASQAYASSKRD

Sequences:

>Translated_291_residues
MTAAKTLRTLLAQDKCHVMPCCFDALSAKLIAQEGYDLTFMSGFAASASRIGAPDLGLMSYGEVVDQARNIATAIDIPLI
GDGDTGYGNAMNVRRTVTGFAQAGCASVMIEDQLAPKRCGHTPGKAVVPRQEAYDRIKAAVDARDALREDGGDILILART
DARHEHGLSEAIERAAVFAELGADILFVEAPKSIAEMQDICSNLPGPKMANIVEGGETPDLPNAALHDIGYSIAAYPLSL
MAAAMQAMVTSLRAMRADQRPGLMDFGELRSRIGFDDYYAASQAYASSKRD
>Mature_290_residues
TAAKTLRTLLAQDKCHVMPCCFDALSAKLIAQEGYDLTFMSGFAASASRIGAPDLGLMSYGEVVDQARNIATAIDIPLIG
DGDTGYGNAMNVRRTVTGFAQAGCASVMIEDQLAPKRCGHTPGKAVVPRQEAYDRIKAAVDARDALREDGGDILILARTD
ARHEHGLSEAIERAAVFAELGADILFVEAPKSIAEMQDICSNLPGPKMANIVEGGETPDLPNAALHDIGYSIAAYPLSLM
AAAMQAMVTSLRAMRADQRPGLMDFGELRSRIGFDDYYAASQAYASSKRD

Specific function: Catalyzes the formation of proponate and pyruvate from (2R,3S)-2,3-dimethylmalate. Has no activity toward dimethylmaleate, malate, citramalate, isocitrate and citrate [H]

COG id: COG2513

COG function: function code G; PEP phosphonomutase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isocitrate lyase/PEP mutase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786525, Length=236, Percent_Identity=38.9830508474576, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1790445, Length=168, Percent_Identity=30.952380952381, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000918
- InterPro:   IPR018523
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00463 ICL [H]

EC number: =4.1.3.32 [H]

Molecular weight: Translated: 31023; Mature: 30891

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAKTLRTLLAQDKCHVMPCCFDALSAKLIAQEGYDLTFMSGFAASASRIGAPDLGLMS
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEHHCHHHHHHHCCCCCCCHHH
YGEVVDQARNIATAIDIPLIGDGDTGYGNAMNVRRTVTGFAQAGCASVMIEDQLAPKRCG
HHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCHHHCC
HTPGKAVVPRQEAYDRIKAAVDARDALREDGGDILILARTDARHEHGLSEAIERAAVFAE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHCCHHHHHHHHHHHHH
LGADILFVEAPKSIAEMQDICSNLPGPKMANIVEGGETPDLPNAALHDIGYSIAAYPLSL
HCCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCHHHHHHCHHHHHHHHHH
MAAAMQAMVTSLRAMRADQRPGLMDFGELRSRIGFDDYYAASQAYASSKRD
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TAAKTLRTLLAQDKCHVMPCCFDALSAKLIAQEGYDLTFMSGFAASASRIGAPDLGLMS
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEHHCHHHHHHHCCCCCCCHHH
YGEVVDQARNIATAIDIPLIGDGDTGYGNAMNVRRTVTGFAQAGCASVMIEDQLAPKRCG
HHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCHHHCC
HTPGKAVVPRQEAYDRIKAAVDARDALREDGGDILILARTDARHEHGLSEAIERAAVFAE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHCCHHHHHHHHHHHHH
LGADILFVEAPKSIAEMQDICSNLPGPKMANIVEGGETPDLPNAALHDIGYSIAAYPLSL
HCCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCHHHHHHCHHHHHHHHHH
MAAAMQAMVTSLRAMRADQRPGLMDFGELRSRIGFDDYYAASQAYASSKRD
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA