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The map label for this gene is siaT [H]

Identifier: 110679461

GI number: 110679461

Start: 2084295

End: 2085569

Strand: Direct

Name: siaT [H]

Synonym: RD1_2187

Alternate gene names: 110679461

Gene position: 2084295-2085569 (Clockwise)

Preceding gene: 110679460

Following gene: 110679462

Centisome position: 50.43

GC content: 60.47

Gene sequence:

>1275_bases
ATGACCATTCTGCTTATTCTGGGCTCCCTTTTCGGGCTGTTGCTGGTCGGGGTGCCGGTGGCCTTTGCGCTGGGGGGCAT
GGGGCTTGGCATGTTGTTGCTGGGCGGTTTTTCACCGCTCATGGCGCCGCAATCGCTGCTCTCTACCTTGGATGGTTTCA
TCCTTCTGGCGGTGCCGCTGTTTCTGCTGATGTCGAACCTGCTGCTCAAGGGGGGCGTCGGGCGTGACCTTTTTTCGGCC
GTACAGGCCTGGGTCGGGCACTGGCCGGGGGGGCTTGCCGTTGCTACCATTCTCAGCTGCGCGCTTTTTGCCGCCATCTC
AGGCTCGTCCGTCGCGACGGCAGCCACGATTGGCACGGTGGCCATTCCGGAGATGATAAACCGGGGATATGAAAAACGCT
TTGTTTACGGGTTGCTGGCGGCGGGCGGCACGCTGGGCATTTTGATACCGCCCTCCATTCCGATGATCGTCTATGGCTTT
GTGACCGAGCAATCGGTGATTGCGCTGTTTCTGGCAGGCATCGGGCCGGGGGCTGTGCTGGTCACATTGTTCGTGCTTTT
CGCGATGTTGCACGCGCGCCTTTGGGGCGGGTACACGCCGGTGCCCAAGGCGTCGATGCGCGAACGCGCGACAGCCTCCA
AACGCGCATTGCCCTCTGTGGCGCTTGCGGCTCTGGTCATTCTCGGTCTCTATTCCGGGGCGTTCACCCCTACGGAAGCG
GCTGCGATTGGCTTTGCTGCGGCCCTGTTGATCACCGTATTCTGGTTGCGCACCATGACGTGGGCTAAATTCTGGGAAGC
GGTGCGCGAATCCGCGATCACCACGGCCGCGATCCTGTTGATCGTGGCGGGGGCGAAAATCTTTGGCAAGGCCATCGCCC
TCTATCGCATCCCGCAGGATATTTCGGCCTTCCTGGCCCAGACCATCGACGGGCCGATCATGTTCATTCTGGTCGTCTCG
GTCGTGCTGTTGTTGATGGGGCTGGTGTTCGAGGCCCTGTCGATGATCCTGATCATGACGCCGGTGCTGTTGCCCGCGGC
GATGGGTCTGGGCTTCGATCCGATCTGGTTTGGCATCTACATGGTGATCATGGTGGAATGCGCCCTGATCACGCCGCCGG
TGGGTCTAAACCTCTACGTCATACAATCGGTTGCGCGCGCCACGCTGGCCGATGTTGCGCGCGGGGTCTGGCCGTTCCTG
ATGCTGATGCTGTTCACGGTTGGCATTCTTTATCTGGTGCCTGATCTGGCGCTTTATATCCCGTTCAAATGGTGA

Upstream 100 bases:

>100_bases
TGTCTGTGCCCGTGGGGTTTGGCATGCTCGCCTTGCAGGGTCTTGTTGAGTTGATCCGACTGCCCGGCGCGGGCACCACA
AGCCTTGGAGCGACACACGA

Downstream 100 bases:

>100_bases
AATCATGACTGCTGCGAAAACGCTCCGTACCTTGCTGGCGCAGGATAAATGCCATGTGATGCCGTGTTGCTTTGATGCGC
TCTCGGCCAAACTGATCGCG

Product: TRAP transporter, DctM subunit, putative

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MTILLILGSLFGLLLVGVPVAFALGGMGLGMLLLGGFSPLMAPQSLLSTLDGFILLAVPLFLLMSNLLLKGGVGRDLFSA
VQAWVGHWPGGLAVATILSCALFAAISGSSVATAATIGTVAIPEMINRGYEKRFVYGLLAAGGTLGILIPPSIPMIVYGF
VTEQSVIALFLAGIGPGAVLVTLFVLFAMLHARLWGGYTPVPKASMRERATASKRALPSVALAALVILGLYSGAFTPTEA
AAIGFAAALLITVFWLRTMTWAKFWEAVRESAITTAAILLIVAGAKIFGKAIALYRIPQDISAFLAQTIDGPIMFILVVS
VVLLLMGLVFEALSMILIMTPVLLPAAMGLGFDPIWFGIYMVIMVECALITPPVGLNLYVIQSVARATLADVARGVWPFL
MLMLFTVGILYLVPDLALYIPFKW

Sequences:

>Translated_424_residues
MTILLILGSLFGLLLVGVPVAFALGGMGLGMLLLGGFSPLMAPQSLLSTLDGFILLAVPLFLLMSNLLLKGGVGRDLFSA
VQAWVGHWPGGLAVATILSCALFAAISGSSVATAATIGTVAIPEMINRGYEKRFVYGLLAAGGTLGILIPPSIPMIVYGF
VTEQSVIALFLAGIGPGAVLVTLFVLFAMLHARLWGGYTPVPKASMRERATASKRALPSVALAALVILGLYSGAFTPTEA
AAIGFAAALLITVFWLRTMTWAKFWEAVRESAITTAAILLIVAGAKIFGKAIALYRIPQDISAFLAQTIDGPIMFILVVS
VVLLLMGLVFEALSMILIMTPVLLPAAMGLGFDPIWFGIYMVIMVECALITPPVGLNLYVIQSVARATLADVARGVWPFL
MLMLFTVGILYLVPDLALYIPFKW
>Mature_423_residues
TILLILGSLFGLLLVGVPVAFALGGMGLGMLLLGGFSPLMAPQSLLSTLDGFILLAVPLFLLMSNLLLKGGVGRDLFSAV
QAWVGHWPGGLAVATILSCALFAAISGSSVATAATIGTVAIPEMINRGYEKRFVYGLLAAGGTLGILIPPSIPMIVYGFV
TEQSVIALFLAGIGPGAVLVTLFVLFAMLHARLWGGYTPVPKASMRERATASKRALPSVALAALVILGLYSGAFTPTEAA
AIGFAAALLITVFWLRTMTWAKFWEAVRESAITTAAILLIVAGAKIFGKAIALYRIPQDISAFLAQTIDGPIMFILVVSV
VLLLMGLVFEALSMILIMTPVLLPAAMGLGFDPIWFGIYMVIMVECALITPPVGLNLYVIQSVARATLADVARGVWPFLM
LMLFTVGILYLVPDLALYIPFKW

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=426, Percent_Identity=34.2723004694836, Blast_Score=197, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 44807; Mature: 44676

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILLILGSLFGLLLVGVPVAFALGGMGLGMLLLGGFSPLMAPQSLLSTLDGFILLAVPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHH
FLLMSNLLLKGGVGRDLFSAVQAWVGHWPGGLAVATILSCALFAAISGSSVATAATIGTV
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AIPEMINRGYEKRFVYGLLAAGGTLGILIPPSIPMIVYGFVTEQSVIALFLAGIGPGAVL
HHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
VTLFVLFAMLHARLWGGYTPVPKASMRERATASKRALPSVALAALVILGLYSGAFTPTEA
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHH
AAIGFAAALLITVFWLRTMTWAKFWEAVRESAITTAAILLIVAGAKIFGKAIALYRIPQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ISAFLAQTIDGPIMFILVVSVVLLLMGLVFEALSMILIMTPVLLPAAMGLGFDPIWFGIY
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
MVIMVECALITPPVGLNLYVIQSVARATLADVARGVWPFLMLMLFTVGILYLVPDLALYI
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PFKW
CCCC
>Mature Secondary Structure 
TILLILGSLFGLLLVGVPVAFALGGMGLGMLLLGGFSPLMAPQSLLSTLDGFILLAVPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHH
FLLMSNLLLKGGVGRDLFSAVQAWVGHWPGGLAVATILSCALFAAISGSSVATAATIGTV
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AIPEMINRGYEKRFVYGLLAAGGTLGILIPPSIPMIVYGFVTEQSVIALFLAGIGPGAVL
HHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
VTLFVLFAMLHARLWGGYTPVPKASMRERATASKRALPSVALAALVILGLYSGAFTPTEA
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHH
AAIGFAAALLITVFWLRTMTWAKFWEAVRESAITTAAILLIVAGAKIFGKAIALYRIPQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ISAFLAQTIDGPIMFILVVSVVLLLMGLVFEALSMILIMTPVLLPAAMGLGFDPIWFGIY
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
MVIMVECALITPPVGLNLYVIQSVARATLADVARGVWPFLMLMLFTVGILYLVPDLALYI
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PFKW
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]