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The map label for this gene is mpp [C]

Identifier: 110679417

GI number: 110679417

Start: 2040350

End: 2041612

Strand: Direct

Name: mpp [C]

Synonym: RD1_2142

Alternate gene names: 110679417

Gene position: 2040350-2041612 (Clockwise)

Preceding gene: 110679416

Following gene: 110679418

Centisome position: 49.37

GC content: 60.49

Gene sequence:

>1263_bases
GTGACATTGAACCAACACCGCCTGCCGAATGGCTTTCGCATTGTAACGGAACATATGCCGGGGCTTGCCTCTGCCTCGAT
CGGCGTCTGGGTCACGGCGGGGGCACGTCATGAAACGCCGCAACAAAACGGCATCGCCCATTTTCTGGAACATATGGCGT
TCAAGGGTACGACGCAGCGCACAGCCTTGCAGATCGCGGAAAGCATCGAGGATGTGGGCGGCTACATCAACGCCTATACC
AGCCGGGAGGTGACGGCCTATTACGCGCGGGTGTTGCAAAACGATGTCCCGCTGGCACTGGATGTGATTGCGGATATTCT
GCTCAATCCCACGCTGGAAGAGGCCGAGATCGAAGTCGAGCGTGGTGTTATCCTGCAGGAAATCGGCCAGTCGCTGGACA
CGCCGGACGATGTGATTTTCGACTGGCTTCAGGAAGAAGCCTATCCAAACCACCCCATGGGGCGCACCATTCTGGGACCG
AGCGAGCGGGTATCGCAGTTTTCAAGGAATGATCTGCAGCAGTTCATCGCTCAGCACTACGGACCCGAACAGATGATCCT
GTCGGCGGCTGGCGCTGTGGATCACGATGAGATCGTGCGCCTCGCGGAGCAGCTTTTCGGCAGCATGCAGGCCAAACCGA
TGTTTGATGTGGATGCCGCGCAGTTTCTGGGCGGTGAGCGTCGCCAGAGCAAAGCGCTCGAGCAGGCGCATTTTGCGCTG
GCCTTTGAAAGCCCCGGCTACCGGGATGATTGCATCTATACGGCGCAGATTTACGCCTCTGCACTGGGGGGCGGCATGTC
GAGCCGCCTGTTTCAGGAAATCCGCGAAAACCGTGGCCTGTGCTATTCGATCTTTGCACAAGCCGGGGCCTATGCCGACA
CCGGTATGACGACGATCTATGCCGGAACCAGTGCCGAGCAGTTGGGTCAACTGGCGGAGATCACAATCGACGAGATAAAA
CGCGCCGTGGATGACATGTCTCCCGCCGAAGTGGCCCGTGCGCGCGCGCAGATGAAAGCGGGTCTGCTGATGGGGCTGGA
AAGCCCCTCCAACCGCGCAGAACGGCTGGCGCGTCTGGTGCAGATCTGGGACCGGGTGCCGCCACTGGATGAAACAGTGG
CGATGATCGACGCGGTGACCACCGGGGACGTGCGTGAATTTGCCCAAAGAATTGCGCAAAGTGCACCGGCGGCCCTCGCG
CTTTACGGGCCGGTTGACGGCGCGCCGACGCTGGCGGCTCTGCAGGAGCGCCGTGCAGCGTGA

Upstream 100 bases:

>100_bases
CTGCGCGCATGGCGGACCTGTATGACCGCACCGAAAGGGTGACTCGCGTGCCAAACGATCTGGCCGCCCTCAAAGACCAC
ATAAAAGGGCACATCTGAGC

Downstream 100 bases:

>100_bases
TACTTCGCGGTCGTCGCAAACTCAGGATCGAGACGGAGCGGATGACATTGCGCCCGCCGGTCCATTCGGATTTCCGCGCG
TGGTCGCACCTGCGTGCGCA

Product: M16 family peptidase putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MTLNQHRLPNGFRIVTEHMPGLASASIGVWVTAGARHETPQQNGIAHFLEHMAFKGTTQRTALQIAESIEDVGGYINAYT
SREVTAYYARVLQNDVPLALDVIADILLNPTLEEAEIEVERGVILQEIGQSLDTPDDVIFDWLQEEAYPNHPMGRTILGP
SERVSQFSRNDLQQFIAQHYGPEQMILSAAGAVDHDEIVRLAEQLFGSMQAKPMFDVDAAQFLGGERRQSKALEQAHFAL
AFESPGYRDDCIYTAQIYASALGGGMSSRLFQEIRENRGLCYSIFAQAGAYADTGMTTIYAGTSAEQLGQLAEITIDEIK
RAVDDMSPAEVARARAQMKAGLLMGLESPSNRAERLARLVQIWDRVPPLDETVAMIDAVTTGDVREFAQRIAQSAPAALA
LYGPVDGAPTLAALQERRAA

Sequences:

>Translated_420_residues
MTLNQHRLPNGFRIVTEHMPGLASASIGVWVTAGARHETPQQNGIAHFLEHMAFKGTTQRTALQIAESIEDVGGYINAYT
SREVTAYYARVLQNDVPLALDVIADILLNPTLEEAEIEVERGVILQEIGQSLDTPDDVIFDWLQEEAYPNHPMGRTILGP
SERVSQFSRNDLQQFIAQHYGPEQMILSAAGAVDHDEIVRLAEQLFGSMQAKPMFDVDAAQFLGGERRQSKALEQAHFAL
AFESPGYRDDCIYTAQIYASALGGGMSSRLFQEIRENRGLCYSIFAQAGAYADTGMTTIYAGTSAEQLGQLAEITIDEIK
RAVDDMSPAEVARARAQMKAGLLMGLESPSNRAERLARLVQIWDRVPPLDETVAMIDAVTTGDVREFAQRIAQSAPAALA
LYGPVDGAPTLAALQERRAA
>Mature_419_residues
TLNQHRLPNGFRIVTEHMPGLASASIGVWVTAGARHETPQQNGIAHFLEHMAFKGTTQRTALQIAESIEDVGGYINAYTS
REVTAYYARVLQNDVPLALDVIADILLNPTLEEAEIEVERGVILQEIGQSLDTPDDVIFDWLQEEAYPNHPMGRTILGPS
ERVSQFSRNDLQQFIAQHYGPEQMILSAAGAVDHDEIVRLAEQLFGSMQAKPMFDVDAAQFLGGERRQSKALEQAHFALA
FESPGYRDDCIYTAQIYASALGGGMSSRLFQEIRENRGLCYSIFAQAGAYADTGMTTIYAGTSAEQLGQLAEITIDEIKR
AVDDMSPAEVARARAQMKAGLLMGLESPSNRAERLARLVQIWDRVPPLDETVAMIDAVTTGDVREFAQRIAQSAPAALAL
YGPVDGAPTLAALQERRAA

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=415, Percent_Identity=37.1084337349398, Blast_Score=277, Evalue=1e-74,
Organism=Homo sapiens, GI46593007, Length=416, Percent_Identity=31.9711538461538, Blast_Score=222, Evalue=6e-58,
Organism=Homo sapiens, GI24308013, Length=440, Percent_Identity=26.8181818181818, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI50592988, Length=421, Percent_Identity=23.5154394299287, Blast_Score=108, Evalue=7e-24,
Organism=Escherichia coli, GI1787770, Length=220, Percent_Identity=24.0909090909091, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI2367164, Length=211, Percent_Identity=26.5402843601896, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71999683, Length=414, Percent_Identity=31.8840579710145, Blast_Score=225, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI17553678, Length=421, Percent_Identity=30.4038004750594, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17510601, Length=448, Percent_Identity=23.4375, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17569737, Length=425, Percent_Identity=23.0588235294118, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17555260, Length=252, Percent_Identity=21.4285714285714, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323192, Length=433, Percent_Identity=34.6420323325635, Blast_Score=255, Evalue=9e-69,
Organism=Saccharomyces cerevisiae, GI6321813, Length=406, Percent_Identity=26.6009852216749, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6319426, Length=422, Percent_Identity=26.0663507109005, Blast_Score=106, Evalue=5e-24,
Organism=Drosophila melanogaster, GI21357875, Length=414, Percent_Identity=35.7487922705314, Blast_Score=261, Evalue=9e-70,
Organism=Drosophila melanogaster, GI24646943, Length=414, Percent_Identity=35.7487922705314, Blast_Score=261, Evalue=9e-70,
Organism=Drosophila melanogaster, GI19921772, Length=442, Percent_Identity=24.8868778280543, Blast_Score=151, Evalue=9e-37,
Organism=Drosophila melanogaster, GI24665395, Length=380, Percent_Identity=22.6315789473684, Blast_Score=82, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 45981; Mature: 45850

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLNQHRLPNGFRIVTEHMPGLASASIGVWVTAGARHETPQQNGIAHFLEHMAFKGTTQR
CCCCCCCCCCCCEEHHHHCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHH
TALQIAESIEDVGGYINAYTSREVTAYYARVLQNDVPLALDVIADILLNPTLEEAEIEVE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHH
RGVILQEIGQSLDTPDDVIFDWLQEEAYPNHPMGRTILGPSERVSQFSRNDLQQFIAQHY
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GPEQMILSAAGAVDHDEIVRLAEQLFGSMQAKPMFDVDAAQFLGGERRQSKALEQAHFAL
CHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHEE
AFESPGYRDDCIYTAQIYASALGGGMSSRLFQEIRENRGLCYSIFAQAGAYADTGMTTIY
EECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEHHHHHHCCCCCCCCEEEE
AGTSAEQLGQLAEITIDEIKRAVDDMSPAEVARARAQMKAGLLMGLESPSNRAERLARLV
ECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
QIWDRVPPLDETVAMIDAVTTGDVREFAQRIAQSAPAALALYGPVDGAPTLAALQERRAA
HHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TLNQHRLPNGFRIVTEHMPGLASASIGVWVTAGARHETPQQNGIAHFLEHMAFKGTTQR
CCCCCCCCCCCEEHHHHCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHH
TALQIAESIEDVGGYINAYTSREVTAYYARVLQNDVPLALDVIADILLNPTLEEAEIEVE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHH
RGVILQEIGQSLDTPDDVIFDWLQEEAYPNHPMGRTILGPSERVSQFSRNDLQQFIAQHY
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GPEQMILSAAGAVDHDEIVRLAEQLFGSMQAKPMFDVDAAQFLGGERRQSKALEQAHFAL
CHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHEE
AFESPGYRDDCIYTAQIYASALGGGMSSRLFQEIRENRGLCYSIFAQAGAYADTGMTTIY
EECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEHHHHHHCCCCCCCCEEEE
AGTSAEQLGQLAEITIDEIKRAVDDMSPAEVARARAQMKAGLLMGLESPSNRAERLARLV
ECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
QIWDRVPPLDETVAMIDAVTTGDVREFAQRIAQSAPAALALYGPVDGAPTLAALQERRAA
HHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA