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The map label for this gene is dxnG [H]

Identifier: 110679405

GI number: 110679405

Start: 2028064

End: 2028759

Strand: Reverse

Name: dxnG [H]

Synonym: RD1_2130

Alternate gene names: 110679405

Gene position: 2028759-2028064 (Counterclockwise)

Preceding gene: 110679406

Following gene: 110679404

Centisome position: 49.09

GC content: 57.18

Gene sequence:

>696_bases
ATGAATAAAGTGTACGGATCGGCCTCTGAGGCGCTTGAGGGAGTTTTGCACGACGGCATGCTCATCGCGGCGGGGGGCTT
TGGGTTATGTGGCATCCCCGAATTGCTGCTCTCTGCGATCCGCGATGCTGGCACCAAGGACCTGACCTTTGCCTCCAATA
ACGCCGGTGTTGATGATTTCGGCATCGGCATTTTGCTGCAGACACGGCAGGTCAAGAAAATGATCTCCTCCTATGTCGGC
GAGAATGCGGAATTCATGCGCCAGTACCTGTCGGGCGAATTGGAGCTGGAATTCAACCCGCAAGGGACTTTGGCCGAACG
GATGCGCGCGGGCGGCTGCGGCATACCCGGATTTTACACAAAAACCGGCGTCGGCACGGTGATTGCCGACGGCAAGGAGC
ACAAGGATTTCGATGGAGAGACCTACATCCTCGAACGCGGCATTGTTGCGGATCTGTCCATCGTAAAAGCGTGGAAGGCG
GATGCGACCGGCAACCTGGTGTTCAGAAAAACCGCGCGCAACTTCAACCCGCCCGCCGCGATGTGCGGAAAAATCTGCGT
GGTTGAGGTTGAAGAGATCGTGCCAACTGGCAGCCTTGATCCCGACAGCATCCACCTGCCCGGCATCTATGTGCATCGCC
TGATACAGGGCGAACACGAAAAACGCATTGAACAGCGCACCACAAGGGCCGCGTAA

Upstream 100 bases:

>100_bases
TGCGTGAAATAAAACGTGGGCAACACCGGCCTGCGCTGTGGCAATACACCACAAATTTGTCATCGGCTTCCGGTTCGCAG
AGTAGAAGTAAGGAAGCACG

Downstream 100 bases:

>100_bases
GGCGCAGGGTATGGCAGATACGAATACGAAAACGCGCAGCGATGCGACGCATGCGGCGGGGACACCATCGGAGAAAGACT
TCGGCGGGTTTTCCCGCTCT

Product: 3-oxoadipate CoA-succinyl transferase, alpha subunit

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MNKVYGSASEALEGVLHDGMLIAAGGFGLCGIPELLLSAIRDAGTKDLTFASNNAGVDDFGIGILLQTRQVKKMISSYVG
ENAEFMRQYLSGELELEFNPQGTLAERMRAGGCGIPGFYTKTGVGTVIADGKEHKDFDGETYILERGIVADLSIVKAWKA
DATGNLVFRKTARNFNPPAAMCGKICVVEVEEIVPTGSLDPDSIHLPGIYVHRLIQGEHEKRIEQRTTRAA

Sequences:

>Translated_231_residues
MNKVYGSASEALEGVLHDGMLIAAGGFGLCGIPELLLSAIRDAGTKDLTFASNNAGVDDFGIGILLQTRQVKKMISSYVG
ENAEFMRQYLSGELELEFNPQGTLAERMRAGGCGIPGFYTKTGVGTVIADGKEHKDFDGETYILERGIVADLSIVKAWKA
DATGNLVFRKTARNFNPPAAMCGKICVVEVEEIVPTGSLDPDSIHLPGIYVHRLIQGEHEKRIEQRTTRAA
>Mature_231_residues
MNKVYGSASEALEGVLHDGMLIAAGGFGLCGIPELLLSAIRDAGTKDLTFASNNAGVDDFGIGILLQTRQVKKMISSYVG
ENAEFMRQYLSGELELEFNPQGTLAERMRAGGCGIPGFYTKTGVGTVIADGKEHKDFDGETYILERGIVADLSIVKAWKA
DATGNLVFRKTARNFNPPAAMCGKICVVEVEEIVPTGSLDPDSIHLPGIYVHRLIQGEHEKRIEQRTTRAA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=247, Percent_Identity=53.8461538461538, Blast_Score=269, Evalue=1e-72,
Organism=Homo sapiens, GI11545841, Length=244, Percent_Identity=49.1803278688525, Blast_Score=226, Evalue=1e-59,
Organism=Escherichia coli, GI1788551, Length=208, Percent_Identity=43.2692307692308, Blast_Score=183, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17531517, Length=244, Percent_Identity=52.4590163934426, Blast_Score=256, Evalue=5e-69,
Organism=Drosophila melanogaster, GI21358325, Length=242, Percent_Identity=51.2396694214876, Blast_Score=250, Evalue=5e-67,
Organism=Drosophila melanogaster, GI24655794, Length=242, Percent_Identity=51.2396694214876, Blast_Score=250, Evalue=5e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 24919; Mature: 24919

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVYGSASEALEGVLHDGMLIAAGGFGLCGIPELLLSAIRDAGTKDLTFASNNAGVDDF
CCCCCCCHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCC
GIGILLQTRQVKKMISSYVGENAEFMRQYLSGELELEFNPQGTLAERMRAGGCGIPGFYT
CCEEEEHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCCCC
KTGVGTVIADGKEHKDFDGETYILERGIVADLSIVKAWKADATGNLVFRKTARNFNPPAA
CCCCCEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHH
MCGKICVVEVEEIVPTGSLDPDSIHLPGIYVHRLIQGEHEKRIEQRTTRAA
HHCCEEEEEHHHHCCCCCCCCCCEECCHHHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKVYGSASEALEGVLHDGMLIAAGGFGLCGIPELLLSAIRDAGTKDLTFASNNAGVDDF
CCCCCCCHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCC
GIGILLQTRQVKKMISSYVGENAEFMRQYLSGELELEFNPQGTLAERMRAGGCGIPGFYT
CCEEEEHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCCCC
KTGVGTVIADGKEHKDFDGETYILERGIVADLSIVKAWKADATGNLVFRKTARNFNPPAA
CCCCCEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHH
MCGKICVVEVEEIVPTGSLDPDSIHLPGIYVHRLIQGEHEKRIEQRTTRAA
HHCCEEEEEHHHHCCCCCCCCCCEECCHHHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]