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The map label for this gene is dtd

Identifier: 110679267

GI number: 110679267

Start: 1896516

End: 1896962

Strand: Reverse

Name: dtd

Synonym: RD1_1982

Alternate gene names: 110679267

Gene position: 1896962-1896516 (Counterclockwise)

Preceding gene: 110679268

Following gene: 110679266

Centisome position: 45.9

GC content: 61.74

Gene sequence:

>447_bases
ATGAGGGCGCTGCTGCAACGCGTGAGTTCAGCATCGGTCGCGGTCGATGGGAATACGATCGGCGCGATTGACCATGGGCT
GCTGATCTTCATCTGTGCCATGCCCGGTGACACGAAGGACACAAGCGCGCGACTGGCCGCCAAGATATCACGGTTGCGCG
TGTTCAAGGATGACGCCGGGAAAATGAATCTGAACCTTGCACAAACCGGCGGTGCCGCCCTCGTGGTCAGCCAGTTCACG
CTGGCCGCCGACACCTCGCGTGGCAATCGCCCCGGTTTTTCCGGTGCCGGCAAACCCGCAGAGGCGCAAGCGCTGTACGA
GCAATTCGCGCAGGATCTGCGCGCGCTGGACATTCCCGTGCAGACCGGCCAGTTCGGCGCAGACATGCAGGTATCGCTTT
GCAACGATGGGCCTGTTACGCTCTGGCTTGATACAGCCGATGGCTGA

Upstream 100 bases:

>100_bases
ATCGTCGGTTTATCTATGGCCGCTGCCGTGGGATATTTTTACGCGATGAACCAATGATCCAATCTGTCAAACCGAAACAC
CACCGCGCGGGGGTGACGCG

Downstream 100 bases:

>100_bases
CCTTTTCCTTTCAATGGCGCACAACATCGCATGACACATCAAAACACATTGGTATCCCTGTTTGAGGCTGGCGTCATGGC
GGTGCGGGGTGACAGCGCTG

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MRALLQRVSSASVAVDGNTIGAIDHGLLIFICAMPGDTKDTSARLAAKISRLRVFKDDAGKMNLNLAQTGGAALVVSQFT
LAADTSRGNRPGFSGAGKPAEAQALYEQFAQDLRALDIPVQTGQFGADMQVSLCNDGPVTLWLDTADG

Sequences:

>Translated_148_residues
MRALLQRVSSASVAVDGNTIGAIDHGLLIFICAMPGDTKDTSARLAAKISRLRVFKDDAGKMNLNLAQTGGAALVVSQFT
LAADTSRGNRPGFSGAGKPAEAQALYEQFAQDLRALDIPVQTGQFGADMQVSLCNDGPVTLWLDTADG
>Mature_148_residues
MRALLQRVSSASVAVDGNTIGAIDHGLLIFICAMPGDTKDTSARLAAKISRLRVFKDDAGKMNLNLAQTGGAALVVSQFT
LAADTSRGNRPGFSGAGKPAEAQALYEQFAQDLRALDIPVQTGQFGADMQVSLCNDGPVTLWLDTADG

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=38.5135135135135, Blast_Score=97, Evalue=6e-21,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=52.4475524475524, Blast_Score=152, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI115533292, Length=155, Percent_Identity=34.1935483870968, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6319982, Length=149, Percent_Identity=40.2684563758389, Blast_Score=111, Evalue=6e-26,
Organism=Drosophila melanogaster, GI281361569, Length=149, Percent_Identity=37.5838926174497, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_ROSDO (Q168K5)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_682274.1
- ProteinModelPortal:   Q168K5
- SMR:   Q168K5
- STRING:   Q168K5
- GeneID:   4196730
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_1982
- NMPDR:   fig|375451.6.peg.1852
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- PhylomeDB:   Q168K5
- ProtClustDB:   PRK05273
- BioCyc:   RDEN375451:RD1_1982-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 15468; Mature: 15468

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALLQRVSSASVAVDGNTIGAIDHGLLIFICAMPGDTKDTSARLAAKISRLRVFKDDAG
CHHHHHHHCCCEEEECCCEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHEEECCCC
KMNLNLAQTGGAALVVSQFTLAADTSRGNRPGFSGAGKPAEAQALYEQFAQDLRALDIPV
EEEEEEECCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
QTGQFGADMQVSLCNDGPVTLWLDTADG
CCCCCCCCEEEEEECCCCEEEEEECCCC
>Mature Secondary Structure
MRALLQRVSSASVAVDGNTIGAIDHGLLIFICAMPGDTKDTSARLAAKISRLRVFKDDAG
CHHHHHHHCCCEEEECCCEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHEEECCCC
KMNLNLAQTGGAALVVSQFTLAADTSRGNRPGFSGAGKPAEAQALYEQFAQDLRALDIPV
EEEEEEECCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
QTGQFGADMQVSLCNDGPVTLWLDTADG
CCCCCCCCEEEEEECCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA