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The map label for this gene is carA [H]

Identifier: 110679250

GI number: 110679250

Start: 1875663

End: 1876823

Strand: Reverse

Name: carA [H]

Synonym: RD1_1963

Alternate gene names: 110679250

Gene position: 1876823-1875663 (Counterclockwise)

Preceding gene: 110679253

Following gene: 110679249

Centisome position: 45.41

GC content: 60.12

Gene sequence:

>1161_bases
ATGACTGTCCCTGCAACCGACCGTCCTACCGCCTGTCTGGCGCTTGCGGATGGCACTCTGTTTTACGGGATGGGATTTGG
CGCAACGGGCCAGACCGTGGCTGAGCTCTGCTTCAACACGGCCATGACCGGCTATCAGGAAATCATGACAGACCCGTCCT
ATGCCGGGCAGATCGTCACATTCACCTTTCCGCACATCGGCAACGTGGGCGTGAACCCGCAGGATGATGAAACGGCTGAT
CCTTTCGCGGCGGGGATGGTTGTGAAATGGATGCCGACGGAGCCGTCGAACTGGCGGGCCATTCAGCATATTGATGACTG
GTTGACGGCCCGAGGACGCATTGCCATAGGCGGTGTCGACACGCGGCGTCTGACGCGCGCGATCCGTCAATCCGGCGCAC
CGCATGTGGCTCTGACACATGATCCGGACGGCAATTTCGATGTTGAAGCGCTGGTGGCAGCAGCGCGCGGCTTCAGCGGG
CTGGAAGGTCTCGACCTTGCAAAGGAAGTGACCTGCGCGCAATCCTACCACTGGAATGAAATGCGGTGGGCCTGGCCCGA
AGGCTACAGCCCGCAGACCGACCCCAAGCACAAGGTTGTCGCGGTTGATTACGGCGCCAAGCGCAACATCCTGCGCTGCC
TTGCAAGTGCTGGCTGCGATGTGACCGTGCTGCCGGCAACCGCAACTTATGAGGATGTGCTCGCGCATAACCCGGATGGT
GTTTTTCTGTCCAACGGGCCGGGGGATCCGGCGGCGACCGGCGCATATGCCGTGCCCATGATTCGCGGTGTTCTGGACAA
CACGGACCTTCCGGTCTTTGGAATTTGCCTTGGCCATCAGATGCTTGCCCTCGCACTTGGTGCGCAAACCATCAAGATGA
ACCACGGACATCACGGGGCCAACCATCCGGTCAAGGATCACGATACCGGGAAGGTGGAAATCACCTCGATGAATCACGGT
TTTGCGGTGGATGCGCAAACCCTGCCTGATAGGGTCATCGAGACGCATACATCGCTGTTTGACGGGTCCAATTGTGGGAT
TCGCGTGGATGGGCGGCCCGTTTGGTCCGTGCAACACCACCCCGAGGCAAGCCCGGGTCCGCAGGACAGCTATTACCTGT
TCGAACGTTTCGCCAAAGCGATGGCGGAGCGAGCCGCATAG

Upstream 100 bases:

>100_bases
AAACGTGCGGCCAGCAGGTGCCAATCCGCTTGACCCGATCTGCCTGCCCGTCTAGGTATCGCCAGATTTTGCTGGCTCCC
CTTTCCGGAAAGGACATCCC

Downstream 100 bases:

>100_bases
GTCGCATCAAAGGCACTCTCTTAAGTTGAATAATGCAGGTTTAACAGTTCATTAACCGCGATCTGCAAGATTGCATCGTC
CACCAACGATGCAAGGCAAT

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MTVPATDRPTACLALADGTLFYGMGFGATGQTVAELCFNTAMTGYQEIMTDPSYAGQIVTFTFPHIGNVGVNPQDDETAD
PFAAGMVVKWMPTEPSNWRAIQHIDDWLTARGRIAIGGVDTRRLTRAIRQSGAPHVALTHDPDGNFDVEALVAAARGFSG
LEGLDLAKEVTCAQSYHWNEMRWAWPEGYSPQTDPKHKVVAVDYGAKRNILRCLASAGCDVTVLPATATYEDVLAHNPDG
VFLSNGPGDPAATGAYAVPMIRGVLDNTDLPVFGICLGHQMLALALGAQTIKMNHGHHGANHPVKDHDTGKVEITSMNHG
FAVDAQTLPDRVIETHTSLFDGSNCGIRVDGRPVWSVQHHPEASPGPQDSYYLFERFAKAMAERAA

Sequences:

>Translated_386_residues
MTVPATDRPTACLALADGTLFYGMGFGATGQTVAELCFNTAMTGYQEIMTDPSYAGQIVTFTFPHIGNVGVNPQDDETAD
PFAAGMVVKWMPTEPSNWRAIQHIDDWLTARGRIAIGGVDTRRLTRAIRQSGAPHVALTHDPDGNFDVEALVAAARGFSG
LEGLDLAKEVTCAQSYHWNEMRWAWPEGYSPQTDPKHKVVAVDYGAKRNILRCLASAGCDVTVLPATATYEDVLAHNPDG
VFLSNGPGDPAATGAYAVPMIRGVLDNTDLPVFGICLGHQMLALALGAQTIKMNHGHHGANHPVKDHDTGKVEITSMNHG
FAVDAQTLPDRVIETHTSLFDGSNCGIRVDGRPVWSVQHHPEASPGPQDSYYLFERFAKAMAERAA
>Mature_385_residues
TVPATDRPTACLALADGTLFYGMGFGATGQTVAELCFNTAMTGYQEIMTDPSYAGQIVTFTFPHIGNVGVNPQDDETADP
FAAGMVVKWMPTEPSNWRAIQHIDDWLTARGRIAIGGVDTRRLTRAIRQSGAPHVALTHDPDGNFDVEALVAAARGFSGL
EGLDLAKEVTCAQSYHWNEMRWAWPEGYSPQTDPKHKVVAVDYGAKRNILRCLASAGCDVTVLPATATYEDVLAHNPDGV
FLSNGPGDPAATGAYAVPMIRGVLDNTDLPVFGICLGHQMLALALGAQTIKMNHGHHGANHPVKDHDTGKVEITSMNHGF
AVDAQTLPDRVIETHTSLFDGSNCGIRVDGRPVWSVQHHPEASPGPQDSYYLFERFAKAMAERAA

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=385, Percent_Identity=36.8831168831169, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI169790915, Length=382, Percent_Identity=33.2460732984293, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI21361331, Length=382, Percent_Identity=33.2460732984293, Blast_Score=172, Evalue=5e-43,
Organism=Escherichia coli, GI1786215, Length=380, Percent_Identity=51.3157894736842, Blast_Score=378, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI193204318, Length=387, Percent_Identity=36.4341085271318, Blast_Score=225, Evalue=4e-59,
Organism=Saccharomyces cerevisiae, GI6324878, Length=384, Percent_Identity=38.28125, Blast_Score=229, Evalue=8e-61,
Organism=Saccharomyces cerevisiae, GI6322331, Length=395, Percent_Identity=35.4430379746835, Blast_Score=224, Evalue=1e-59,
Organism=Drosophila melanogaster, GI45555749, Length=394, Percent_Identity=37.0558375634518, Blast_Score=226, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24642586, Length=394, Percent_Identity=37.0558375634518, Blast_Score=226, Evalue=2e-59,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 41562; Mature: 41431

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVPATDRPTACLALADGTLFYGMGFGATGQTVAELCFNTAMTGYQEIMTDPSYAGQIVT
CCCCCCCCCCEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
FTFPHIGNVGVNPQDDETADPFAAGMVVKWMPTEPSNWRAIQHIDDWLTARGRIAIGGVD
EECCCCCCCCCCCCCCCCCCCHHCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEECCCC
TRRLTRAIRQSGAPHVALTHDPDGNFDVEALVAAARGFSGLEGLDLAKEVTCAQSYHWNE
HHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCC
MRWAWPEGYSPQTDPKHKVVAVDYGAKRNILRCLASAGCDVTVLPATATYEDVLAHNPDG
CEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCC
VFLSNGPGDPAATGAYAVPMIRGVLDNTDLPVFGICLGHQMLALALGAQTIKMNHGHHGA
EEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCEEEEEECCCCCC
NHPVKDHDTGKVEITSMNHGFAVDAQTLPDRVIETHTSLFDGSNCGIRVDGRPVWSVQHH
CCCCCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHCCCCCCCEEECCEEEEEECCC
PEASPGPQDSYYLFERFAKAMAERAA
CCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVPATDRPTACLALADGTLFYGMGFGATGQTVAELCFNTAMTGYQEIMTDPSYAGQIVT
CCCCCCCCCEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
FTFPHIGNVGVNPQDDETADPFAAGMVVKWMPTEPSNWRAIQHIDDWLTARGRIAIGGVD
EECCCCCCCCCCCCCCCCCCCHHCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEECCCC
TRRLTRAIRQSGAPHVALTHDPDGNFDVEALVAAARGFSGLEGLDLAKEVTCAQSYHWNE
HHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCC
MRWAWPEGYSPQTDPKHKVVAVDYGAKRNILRCLASAGCDVTVLPATATYEDVLAHNPDG
CEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCC
VFLSNGPGDPAATGAYAVPMIRGVLDNTDLPVFGICLGHQMLALALGAQTIKMNHGHHGA
EEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCEEEEEECCCCCC
NHPVKDHDTGKVEITSMNHGFAVDAQTLPDRVIETHTSLFDGSNCGIRVDGRPVWSVQHH
CCCCCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHCCCCCCCEEECCEEEEEECCC
PEASPGPQDSYYLFERFAKAMAERAA
CCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA