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The map label for this gene is degP [H]

Identifier: 110679212

GI number: 110679212

Start: 1835107

End: 1836570

Strand: Direct

Name: degP [H]

Synonym: RD1_1923

Alternate gene names: 110679212

Gene position: 1835107-1836570 (Clockwise)

Preceding gene: 110679211

Following gene: 110679214

Centisome position: 44.4

GC content: 60.38

Gene sequence:

>1464_bases
ATGACATCCCAAACGGTAACCATGCCAAACATAGATTCAGCGCAGACACGGTTTCGGTTATTGATGGTCGCAGTTCTGGC
AATGGCTTTTGCGCTGGTGGCACCGCTCACAGGGCATGCACAACCTGCAAGCCTTGCACCGCTGGCTGAAAAGATCAGCC
CCTCGGTAGTCAATATCACAACCTCGACGACCGTATCACGTCGGACGGGGCCACAGGGGATTGTGCCCGAAGGCTCGCCC
TTCGAGGATTTTTTCCGCGACCGCAATATCGGACCAGAGGGTGCGCCGCGCCGCTCGTCTGCGCTCGGCTCGGGCTTCGT
GATTTCTGAAGATGGCTATGTGGTCACCAACAACCACGTGATTGAAGGCGCGGATGAGATTCTGATCGAATTTTTCGATG
GCGGCGAATTGGTTGCCGAGGTGGTAGGAACGGACCCGAACACCGATATCGCCTTGCTGAAGGTGGAAGCGGATGCGCCA
CTGCCGTTCGTGTCCTTTGGCGACAGTGACAGCGCGCGGGTCGGGGATTGGGTGATCGCTATGGGCAACCCGCTGGGGCA
GGGTTTCTCCGTCTCCGCCGGGATCGTATCGGCACGCAACCGCGAACTCAGTGGCCGCTATGATGACTATATCCAGACCG
ATGCGGCCATCAACCGCGGAAACTCCGGCGGTCCGTTGTTCAACATGGATGGCGAAGTGATTGGCGTGAACACGGCCATC
CTGTCACCGACGGGCGGGTCGATCGGGCTCGGTTTCTCGATGGCCGCAAATGTTGTGACCCGTGTGGTGGACCAGTTGCA
GGAATTCGGCGAGACGCGGCGCGGCTGGTTGGGTGTGCAAATTCAGGACGTGACCGAGGATATGGCCGAAGCGATGGGGC
TTGCCTCGACAGATGGGGCTGCGGTGAATGGTGTGCTGGAGGGTCCGGCAATGGAAGCAGGTATCGAGATCGGCGATGTC
ATCATCAGCTTTGACGGGCGCGACGTGGAAGACACGCGCGGTCTGGTGCGTCAGGTTGGGAATACGCCGGTTGGTGAGGC
TGTGCGCGTTGTCGTGCGGCGGGGCGATGAAACCAAAACCCTGCTTGTGACACTTGGCCGCCGTGAAGAAGCCGAAGGTG
CCGTACCTGCCGTGGCGCAGGCCCCTGAGGATGATGCGCCAACCTCTGCCGAGATGATGGGGCTTACCTTGATGGTGCTG
AACGATGAGTTGCGTGAGCAACTTGGCGCCACGCCGGAAACCGAAGGTCTGGCCGTCATGGAGGTGGACGAAGCATCCGA
AGCCTTTGAGAAAGGCCTGCGCGCCGGGGACGTGATCACCGAAGCTGGCCAGAAAAAGGTGACAAGCATCGCGGATCTTG
AAACCCGCGTTGAAGAAGCCAGGGAAGCCGGGCGCAAGTCGTTGCTGCTGCTGGTGCGCCGTGCGGGTGATCCACGGTTC
GTGGCGCTGTCCCTCGCCGAGTGA

Upstream 100 bases:

>100_bases
ATCTTATGATTTTGAAACTGCATGGCTACATGCAGACTGGCTTAGAGCGCAAAACAAGCGCAGAGTATGACAGGCAACAA
CGTATTTCAGGAGACGACGC

Downstream 100 bases:

>100_bases
TCGGATCGGAAAAAGTGGTAAAAGGGGCGCTCTTGCAGCGCCCTTTTTTGTGCCGGGGAGGGGGTTACTCAGATGCCTTG
TTTTCCTGCACAAGACCATC

Product: serine protease DO-like precursor, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MTSQTVTMPNIDSAQTRFRLLMVAVLAMAFALVAPLTGHAQPASLAPLAEKISPSVVNITTSTTVSRRTGPQGIVPEGSP
FEDFFRDRNIGPEGAPRRSSALGSGFVISEDGYVVTNNHVIEGADEILIEFFDGGELVAEVVGTDPNTDIALLKVEADAP
LPFVSFGDSDSARVGDWVIAMGNPLGQGFSVSAGIVSARNRELSGRYDDYIQTDAAINRGNSGGPLFNMDGEVIGVNTAI
LSPTGGSIGLGFSMAANVVTRVVDQLQEFGETRRGWLGVQIQDVTEDMAEAMGLASTDGAAVNGVLEGPAMEAGIEIGDV
IISFDGRDVEDTRGLVRQVGNTPVGEAVRVVVRRGDETKTLLVTLGRREEAEGAVPAVAQAPEDDAPTSAEMMGLTLMVL
NDELREQLGATPETEGLAVMEVDEASEAFEKGLRAGDVITEAGQKKVTSIADLETRVEEAREAGRKSLLLLVRRAGDPRF
VALSLAE

Sequences:

>Translated_487_residues
MTSQTVTMPNIDSAQTRFRLLMVAVLAMAFALVAPLTGHAQPASLAPLAEKISPSVVNITTSTTVSRRTGPQGIVPEGSP
FEDFFRDRNIGPEGAPRRSSALGSGFVISEDGYVVTNNHVIEGADEILIEFFDGGELVAEVVGTDPNTDIALLKVEADAP
LPFVSFGDSDSARVGDWVIAMGNPLGQGFSVSAGIVSARNRELSGRYDDYIQTDAAINRGNSGGPLFNMDGEVIGVNTAI
LSPTGGSIGLGFSMAANVVTRVVDQLQEFGETRRGWLGVQIQDVTEDMAEAMGLASTDGAAVNGVLEGPAMEAGIEIGDV
IISFDGRDVEDTRGLVRQVGNTPVGEAVRVVVRRGDETKTLLVTLGRREEAEGAVPAVAQAPEDDAPTSAEMMGLTLMVL
NDELREQLGATPETEGLAVMEVDEASEAFEKGLRAGDVITEAGQKKVTSIADLETRVEEAREAGRKSLLLLVRRAGDPRF
VALSLAE
>Mature_486_residues
TSQTVTMPNIDSAQTRFRLLMVAVLAMAFALVAPLTGHAQPASLAPLAEKISPSVVNITTSTTVSRRTGPQGIVPEGSPF
EDFFRDRNIGPEGAPRRSSALGSGFVISEDGYVVTNNHVIEGADEILIEFFDGGELVAEVVGTDPNTDIALLKVEADAPL
PFVSFGDSDSARVGDWVIAMGNPLGQGFSVSAGIVSARNRELSGRYDDYIQTDAAINRGNSGGPLFNMDGEVIGVNTAIL
SPTGGSIGLGFSMAANVVTRVVDQLQEFGETRRGWLGVQIQDVTEDMAEAMGLASTDGAAVNGVLEGPAMEAGIEIGDVI
ISFDGRDVEDTRGLVRQVGNTPVGEAVRVVVRRGDETKTLLVTLGRREEAEGAVPAVAQAPEDDAPTSAEMMGLTLMVLN
DELREQLGATPETEGLAVMEVDEASEAFEKGLRAGDVITEAGQKKVTSIADLETRVEEAREAGRKSLLLLVRRAGDPRFV
ALSLAE

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=333, Percent_Identity=32.1321321321321, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI22129776, Length=333, Percent_Identity=30.3303303303303, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI24308541, Length=279, Percent_Identity=32.9749103942652, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI7019477, Length=293, Percent_Identity=35.4948805460751, Blast_Score=136, Evalue=3e-32,
Organism=Escherichia coli, GI1786356, Length=476, Percent_Identity=36.7647058823529, Blast_Score=261, Evalue=7e-71,
Organism=Escherichia coli, GI1789629, Length=465, Percent_Identity=36.1290322580645, Blast_Score=238, Evalue=7e-64,
Organism=Escherichia coli, GI1789630, Length=271, Percent_Identity=36.90036900369, Blast_Score=163, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24646839, Length=287, Percent_Identity=28.5714285714286, Blast_Score=121, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 51284; Mature: 51153

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSQTVTMPNIDSAQTRFRLLMVAVLAMAFALVAPLTGHAQPASLAPLAEKISPSVVNIT
CCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEEE
TSTTVSRRTGPQGIVPEGSPFEDFFRDRNIGPEGAPRRSSALGSGFVISEDGYVVTNNHV
ECCEECCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHCCCCCEEECCCCEEEECCEE
IEGADEILIEFFDGGELVAEVVGTDPNTDIALLKVEADAPLPFVSFGDSDSARVGDWVIA
ECCCHHEEEEECCCCHHHHHHHCCCCCCCEEEEEEECCCCCCEEEECCCCCCCCCCEEEE
MGNPLGQGFSVSAGIVSARNRELSGRYDDYIQTDAAINRGNSGGPLFNMDGEVIGVNTAI
ECCCCCCCEEECCCHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCEEEEEEEE
LSPTGGSIGLGFSMAANVVTRVVDQLQEFGETRRGWLGVQIQDVTEDMAEAMGLASTDGA
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHCCCCCCCC
AVNGVLEGPAMEAGIEIGDVIISFDGRDVEDTRGLVRQVGNTPVGEAVRVVVRRGDETKT
EECCEECCCCHHCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEE
LLVTLGRREEAEGAVPAVAQAPEDDAPTSAEMMGLTLMVLNDELREQLGATPETEGLAVM
EEEEECCCCCCCCCCCHHHCCCCCCCCCCHHHHCEEEEEECHHHHHHHCCCCCCCCEEEE
EVDEASEAFEKGLRAGDVITEAGQKKVTSIADLETRVEEAREAGRKSLLLLVRRAGDPRF
EECHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHEEHHEECCCCCCE
VALSLAE
EEEEECC
>Mature Secondary Structure 
TSQTVTMPNIDSAQTRFRLLMVAVLAMAFALVAPLTGHAQPASLAPLAEKISPSVVNIT
CCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEEE
TSTTVSRRTGPQGIVPEGSPFEDFFRDRNIGPEGAPRRSSALGSGFVISEDGYVVTNNHV
ECCEECCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHCCCCCEEECCCCEEEECCEE
IEGADEILIEFFDGGELVAEVVGTDPNTDIALLKVEADAPLPFVSFGDSDSARVGDWVIA
ECCCHHEEEEECCCCHHHHHHHCCCCCCCEEEEEEECCCCCCEEEECCCCCCCCCCEEEE
MGNPLGQGFSVSAGIVSARNRELSGRYDDYIQTDAAINRGNSGGPLFNMDGEVIGVNTAI
ECCCCCCCEEECCCHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCEEEEEEEE
LSPTGGSIGLGFSMAANVVTRVVDQLQEFGETRRGWLGVQIQDVTEDMAEAMGLASTDGA
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHCCCCCCCC
AVNGVLEGPAMEAGIEIGDVIISFDGRDVEDTRGLVRQVGNTPVGEAVRVVVRRGDETKT
EECCEECCCCHHCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEE
LLVTLGRREEAEGAVPAVAQAPEDDAPTSAEMMGLTLMVLNDELREQLGATPETEGLAVM
EEEEECCCCCCCCCCCHHHCCCCCCCCCCHHHHCEEEEEECHHHHHHHCCCCCCCCEEEE
EVDEASEAFEKGLRAGDVITEAGQKKVTSIADLETRVEEAREAGRKSLLLLVRRAGDPRF
EECHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHEEHHEECCCCCCE
VALSLAE
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]