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The map label for this gene is bcd [H]

Identifier: 110679014

GI number: 110679014

Start: 1645414

End: 1646550

Strand: Reverse

Name: bcd [H]

Synonym: RD1_1713

Alternate gene names: 110679014

Gene position: 1646550-1645414 (Counterclockwise)

Preceding gene: 110679015

Following gene: 110679013

Centisome position: 39.84

GC content: 59.89

Gene sequence:

>1137_bases
GTGTTCGCGGCCCGTGCGGCGAAATGGGACAGAGAACGCGCCTACTGCTGGGACAATATCACGGATCTGGTTGATGCGCG
GATCATGGGCATGACCATTCCCAAGGAGCTTGGCGGCCTTGGGGCCAGCTATCTGGATGTTGTCAAGGTTGTCGAAGAGG
TGGCCAAGGCCTGCACGCTCACAGCGCGGGTCGTGGTCGAGGCCAATATGGGCGGCATCAGCGCCGTCATGGCCTATGGC
ACGGATACGCAGAAGCAACTCTGTGCGCCGCTGGTTCTGGCCGGAGACAAACCGGCGATCTGCATCACCGAGCCCGATGC
GGGTAGTGCTGCGACCGAAATGCGCACAACCGCCCGAAAGCAGGGCGATACCTATGTGATCAATGGCACGAAACACTGGA
TCACAGGGGGCGGGGTTTCAAAGCTCTACCTGATATTCGCGCGGGTTCTGGACGGTGATGGATCAGACCTCGGGATCGGT
GGATTTATCGTTCATGTGGACCCGGGCGCGGGCATTGAACCGCCCGGTTTTTATGTCCTTGGCCGCGAGAAAACCATGGG
GCTGTGCGGGATGCCCGAGGCTGAACTCAGGTTTGAAAACCTCATGGTGGGTGCAGACATGGCGCTGATCCCGCCATCAG
GTTTCAAACGCGGTTTTGCCGACTTGATGAATGCCTACAATTCTCAACGGGTGGGCGCGGGTATGATTGCGATGGGCGTG
GCGGCAGGTGCATTGGAACATGCGAAAAAATACCTGCTCGAACGCAGGCAATTCGGCCGTCCCTTGGCAGAGTTTCAGGG
GTTGCAATGGATGATCGCCGACATGGACACCCAGCTTTGTGCCGCGCGCCTTTTGTTGCACGCGGCCGCGCAATCGCGCG
GACCCGGTGGCAGCCAGTTCCCTGACATGACCATGGCCGCACGCGCCAAGCTGTTTGCATCGGAAATGGCGATAAAGACC
GTCAGCGATTCCCTGCAAATGTTCGGCGCGCGCGGATATGGAGACCGCGAACCGCTCGAACGCATGTACCGCGACGTTCG
GATGTTCACCATTGGCGGTGGCACGGCGCAAGTGCTGCGCACGCAGATCGCCGGTTCCGTGCTGGGGATCAAAACGCCGC
AAACACGCGATACCTGA

Upstream 100 bases:

>100_bases
GTGACTGCGCAGAAGTCGGCGGCGTTCATGCTGGTTCAAATCAAATCAAGAGGCACTTATGACACGTGATACAGTTGCCA
GGGCGCGCGCGCTTGCGCCT

Downstream 100 bases:

>100_bases
TGAGCGGCGGCGTTGCCATGTCGCGCCGCATTCAAACCAGCCGCGCTTTTCGCAACGATTGTGCTGGATTTATACCTGAC
AGCCGCAGAAATGTGATCCG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MFAARAAKWDRERAYCWDNITDLVDARIMGMTIPKELGGLGASYLDVVKVVEEVAKACTLTARVVVEANMGGISAVMAYG
TDTQKQLCAPLVLAGDKPAICITEPDAGSAATEMRTTARKQGDTYVINGTKHWITGGGVSKLYLIFARVLDGDGSDLGIG
GFIVHVDPGAGIEPPGFYVLGREKTMGLCGMPEAELRFENLMVGADMALIPPSGFKRGFADLMNAYNSQRVGAGMIAMGV
AAGALEHAKKYLLERRQFGRPLAEFQGLQWMIADMDTQLCAARLLLHAAAQSRGPGGSQFPDMTMAARAKLFASEMAIKT
VSDSLQMFGARGYGDREPLERMYRDVRMFTIGGGTAQVLRTQIAGSVLGIKTPQTRDT

Sequences:

>Translated_378_residues
MFAARAAKWDRERAYCWDNITDLVDARIMGMTIPKELGGLGASYLDVVKVVEEVAKACTLTARVVVEANMGGISAVMAYG
TDTQKQLCAPLVLAGDKPAICITEPDAGSAATEMRTTARKQGDTYVINGTKHWITGGGVSKLYLIFARVLDGDGSDLGIG
GFIVHVDPGAGIEPPGFYVLGREKTMGLCGMPEAELRFENLMVGADMALIPPSGFKRGFADLMNAYNSQRVGAGMIAMGV
AAGALEHAKKYLLERRQFGRPLAEFQGLQWMIADMDTQLCAARLLLHAAAQSRGPGGSQFPDMTMAARAKLFASEMAIKT
VSDSLQMFGARGYGDREPLERMYRDVRMFTIGGGTAQVLRTQIAGSVLGIKTPQTRDT
>Mature_378_residues
MFAARAAKWDRERAYCWDNITDLVDARIMGMTIPKELGGLGASYLDVVKVVEEVAKACTLTARVVVEANMGGISAVMAYG
TDTQKQLCAPLVLAGDKPAICITEPDAGSAATEMRTTARKQGDTYVINGTKHWITGGGVSKLYLIFARVLDGDGSDLGIG
GFIVHVDPGAGIEPPGFYVLGREKTMGLCGMPEAELRFENLMVGADMALIPPSGFKRGFADLMNAYNSQRVGAGMIAMGV
AAGALEHAKKYLLERRQFGRPLAEFQGLQWMIADMDTQLCAARLLLHAAAQSRGPGGSQFPDMTMAARAKLFASEMAIKT
VSDSLQMFGARGYGDREPLERMYRDVRMFTIGGGTAQVLRTQIAGSVLGIKTPQTRDT

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=364, Percent_Identity=33.2417582417582, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI4501859, Length=348, Percent_Identity=33.0459770114943, Blast_Score=168, Evalue=9e-42,
Organism=Homo sapiens, GI4557231, Length=365, Percent_Identity=32.8767123287671, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI187960098, Length=365, Percent_Identity=32.8767123287671, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI7656849, Length=373, Percent_Identity=31.0991957104558, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI21361497, Length=365, Percent_Identity=31.7808219178082, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI226958414, Length=356, Percent_Identity=29.4943820224719, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI226958412, Length=369, Percent_Identity=29.2682926829268, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI4557235, Length=362, Percent_Identity=28.7292817679558, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI76496475, Length=362, Percent_Identity=28.7292817679558, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI4501857, Length=343, Percent_Identity=27.1137026239067, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI48976061, Length=311, Percent_Identity=27.0096463022508, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI7669494, Length=223, Percent_Identity=32.7354260089686, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI211971008, Length=311, Percent_Identity=27.0096463022508, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4503943, Length=223, Percent_Identity=32.7354260089686, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI38505218, Length=331, Percent_Identity=25.6797583081571, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI87081958, Length=358, Percent_Identity=29.3296089385475, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1786223, Length=371, Percent_Identity=26.6846361185984, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17506239, Length=337, Percent_Identity=32.6409495548961, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17534899, Length=367, Percent_Identity=32.6975476839237, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17508101, Length=345, Percent_Identity=32.1739130434783, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17569725, Length=372, Percent_Identity=31.1827956989247, Blast_Score=171, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17570075, Length=367, Percent_Identity=29.1553133514986, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17533517, Length=366, Percent_Identity=30.6010928961749, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71990804, Length=299, Percent_Identity=33.1103678929766, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17538396, Length=356, Percent_Identity=29.4943820224719, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI71985184, Length=343, Percent_Identity=32.0699708454811, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI32563615, Length=249, Percent_Identity=30.1204819277108, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17551932, Length=336, Percent_Identity=26.7857142857143, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17505929, Length=361, Percent_Identity=26.0387811634349, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI71985192, Length=279, Percent_Identity=30.4659498207885, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17534353, Length=291, Percent_Identity=27.1477663230241, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71982178, Length=242, Percent_Identity=26.4462809917355, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562446, Length=328, Percent_Identity=26.5243902439024, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI86563381, Length=248, Percent_Identity=27.4193548387097, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86563383, Length=252, Percent_Identity=26.984126984127, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356377, Length=368, Percent_Identity=33.4239130434783, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24660351, Length=361, Percent_Identity=31.5789473684211, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24666513, Length=360, Percent_Identity=32.5, Blast_Score=161, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24646207, Length=368, Percent_Identity=32.8804347826087, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI21355753, Length=339, Percent_Identity=31.2684365781711, Blast_Score=144, Evalue=7e-35,
Organism=Drosophila melanogaster, GI281363737, Length=350, Percent_Identity=30, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI19920834, Length=259, Percent_Identity=31.6602316602317, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 40565; Mature: 40565

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAARAAKWDRERAYCWDNITDLVDARIMGMTIPKELGGLGASYLDVVKVVEEVAKACTL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHH
TARVVVEANMGGISAVMAYGTDTQKQLCAPLVLAGDKPAICITEPDAGSAATEMRTTARK
EEEEEEEECCCCEEEEEECCCCCHHHHHCCEEEECCCCEEEEECCCCCCHHHHHHHHHHH
QGDTYVINGTKHWITGGGVSKLYLIFARVLDGDGSDLGIGGFIVHVDPGAGIEPPGFYVL
CCCEEEECCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCEEEE
GREKTMGLCGMPEAELRFENLMVGADMALIPPSGFKRGFADLMNAYNSQRVGAGMIAMGV
ECCCCCCCCCCCHHHHHHHHEEEECCEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHH
AAGALEHAKKYLLERRQFGRPLAEFQGLQWMIADMDTQLCAARLLLHAAAQSRGPGGSQF
HHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEHHCCHHHHHHHHHHHHHHHCCCCCCCCC
PDMTMAARAKLFASEMAIKTVSDSLQMFGARGYGDREPLERMYRDVRMFTIGGGTAQVLR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEEEECCCHHHHHH
TQIAGSVLGIKTPQTRDT
HHHHCCEEECCCCCCCCC
>Mature Secondary Structure
MFAARAAKWDRERAYCWDNITDLVDARIMGMTIPKELGGLGASYLDVVKVVEEVAKACTL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHH
TARVVVEANMGGISAVMAYGTDTQKQLCAPLVLAGDKPAICITEPDAGSAATEMRTTARK
EEEEEEEECCCCEEEEEECCCCCHHHHHCCEEEECCCCEEEEECCCCCCHHHHHHHHHHH
QGDTYVINGTKHWITGGGVSKLYLIFARVLDGDGSDLGIGGFIVHVDPGAGIEPPGFYVL
CCCEEEECCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCEEEE
GREKTMGLCGMPEAELRFENLMVGADMALIPPSGFKRGFADLMNAYNSQRVGAGMIAMGV
ECCCCCCCCCCCHHHHHHHHEEEECCEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHH
AAGALEHAKKYLLERRQFGRPLAEFQGLQWMIADMDTQLCAARLLLHAAAQSRGPGGSQF
HHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEHHCCHHHHHHHHHHHHHHHCCCCCCCCC
PDMTMAARAKLFASEMAIKTVSDSLQMFGARGYGDREPLERMYRDVRMFTIGGGTAQVLR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEEEECCCHHHHHH
TQIAGSVLGIKTPQTRDT
HHHHCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]