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The map label for this gene is tlpA [H]

Identifier: 110678896

GI number: 110678896

Start: 1536349

End: 1536927

Strand: Reverse

Name: tlpA [H]

Synonym: RD1_1590

Alternate gene names: 110678896

Gene position: 1536927-1536349 (Counterclockwise)

Preceding gene: 110678903

Following gene: 110678895

Centisome position: 37.19

GC content: 57.51

Gene sequence:

>579_bases
ATGAAAAATATTGTTTCCGCGCTCGTTTATACGGCCCTTTCCTTGGGTGCAATCACCGTGGGCACGACGGCCCATGCCGA
TCTTGCGGCCGCAGCAGAAATGCGCGACGGCGACATGAAAAAACTGGTGTTTCATGCGACCCCGCAGGATACGTCGGATG
CGGCGTTCTTTCTGGAAGATGATGGCGGCACAACCACGTTGGAAAGCTACCGGGGCAAATACGTATTGCTGAATTTCTGG
GCGACATGGTGTGCGCCCTGCCGGGTTGAGATGCCCCACCTGTCCGAATTGCAGACAGAATTCGGCGGGGACGATTTCGA
GGTGCTTACCATTGCGACGGGACGAAATTCGCCCACCGGTATCAAGAAATTCTTTGAAGAGATCGGCGTGGATAATCTGC
CCCGCCATCAGGACCCAAAACAGGCGCTTGCCAGCGAGATGGCGATCTTTGGACTGCCGATCACCGTGTTGATAGACCCC
GAGGGCAAGGAAGTCGCCCGCCTGCGCGGCGACGCGGATTGGGCATCGGACAACGCCAAGGCGATCATCGAAACGATCCT
CGCGCGCGCACCATCCTGA

Upstream 100 bases:

>100_bases
TGATCGCATCGGGTCCGTCCGCAAAACGGCCGCCCCACATCTGATTGGAAGATTTCGGGTTTTGCGTGTCTGTCATCTGT
GTTCACCCTTTGGAGGGAAA

Downstream 100 bases:

>100_bases
TTAAAACGGCTGCTGCGCAGGAAACAATGGACCTGTGACCAGATTTCTCTAGGCTGATGGATATTCAATCGATTGGTTTT
TGAGAGGCCCGCACCGTGCC

Product: thiol:disulfide interchange protein tlpA, putative

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MKNIVSALVYTALSLGAITVGTTAHADLAAAAEMRDGDMKKLVFHATPQDTSDAAFFLEDDGGTTTLESYRGKYVLLNFW
ATWCAPCRVEMPHLSELQTEFGGDDFEVLTIATGRNSPTGIKKFFEEIGVDNLPRHQDPKQALASEMAIFGLPITVLIDP
EGKEVARLRGDADWASDNAKAIIETILARAPS

Sequences:

>Translated_192_residues
MKNIVSALVYTALSLGAITVGTTAHADLAAAAEMRDGDMKKLVFHATPQDTSDAAFFLEDDGGTTTLESYRGKYVLLNFW
ATWCAPCRVEMPHLSELQTEFGGDDFEVLTIATGRNSPTGIKKFFEEIGVDNLPRHQDPKQALASEMAIFGLPITVLIDP
EGKEVARLRGDADWASDNAKAIIETILARAPS
>Mature_192_residues
MKNIVSALVYTALSLGAITVGTTAHADLAAAAEMRDGDMKKLVFHATPQDTSDAAFFLEDDGGTTTLESYRGKYVLLNFW
ATWCAPCRVEMPHLSELQTEFGGDDFEVLTIATGRNSPTGIKKFFEEIGVDNLPRHQDPKQALASEMAIFGLPITVLIDP
EGKEVARLRGDADWASDNAKAIIETILARAPS

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 20817; Mature: 20817

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIVSALVYTALSLGAITVGTTAHADLAAAAEMRDGDMKKLVFHATPQDTSDAAFFLED
CHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEEC
DGGTTTLESYRGKYVLLNFWATWCAPCRVEMPHLSELQTEFGGDDFEVLTIATGRNSPTG
CCCCEEHHHHCCCEEEEEEHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCHH
IKKFFEEIGVDNLPRHQDPKQALASEMAIFGLPITVLIDPEGKEVARLRGDADWASDNAK
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCCCCCCHH
AIIETILARAPS
HHHHHHHHCCCC
>Mature Secondary Structure
MKNIVSALVYTALSLGAITVGTTAHADLAAAAEMRDGDMKKLVFHATPQDTSDAAFFLED
CHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEEC
DGGTTTLESYRGKYVLLNFWATWCAPCRVEMPHLSELQTEFGGDDFEVLTIATGRNSPTG
CCCCEEHHHHCCCEEEEEEHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCHH
IKKFFEEIGVDNLPRHQDPKQALASEMAIFGLPITVLIDPEGKEVARLRGDADWASDNAK
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCCCCCCHH
AIIETILARAPS
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]