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The map label for this gene is ffh [H]

Identifier: 110678638

GI number: 110678638

Start: 1268291

End: 1269808

Strand: Reverse

Name: ffh [H]

Synonym: RD1_1315

Alternate gene names: 110678638

Gene position: 1269808-1268291 (Counterclockwise)

Preceding gene: 110678639

Following gene: 110678637

Centisome position: 30.72

GC content: 61.53

Gene sequence:

>1518_bases
ATGTTTGAAAATCTGTCCGAACGCCTCTCCGGCGTCTTTGACCGTCTGACAAAACAAGGCGCGCTCTCCGAGGAGGACGT
GAAAACCGCCCTGCGCGAGGTTCGCGTCGCCCTGCTGGAGGCGGATGTCTCCCTGCCCGTCGCGCGCGACTTCGTCAAAG
CGGTGCAGGAAAAAGCCACCGGACAGGCGGTCACCAAATCCATCACGCCCGGCCAGCAGGTCGTCAAGATCGTACATGAC
GCGCTGATCGACGTGCTCAAGGGCGAGGGTGAACCCGGCACGCTCAAGGTCGACAACCCGCCCGCCTCGGTCCTGATGGT
CGGCCTGCAAGGCTCGGGTAAAACCACGACCACCGCCAAACTGGCAAAACGCCTCAAGGAAAAAGACGGCAAACGCGTGC
TCATGGCCTCGCTCGACGTCAACCGCCCCGCCGCGATGGAACAACTCGCCATCCTGGGCGCCCAGATCGGCGTCGACACC
CTGCCCATCATCGCCGGACAGGACCCCGTCGCCATCGCCAAACGCGCCAAAACGCAAGCCGGGCTGGGCGGCTATGACGT
CTATATGCTGGACACCGCCGGTCGTCTGTCCATCGACGAAGAGTTGATGCAACAGGTCGAAGCCGTCCGCGACGTCGCCT
CCCCCCGTGAAACGCTGCTGGTGGTCGACGGGCTGACCGGACAGGACGCCGTGCACACCGCGCAGAACTTTGACGAACGC
ATCGGCATCTCCGGCGTGGTGCTGACCCGGATGGACGGTGACGGGCGCGGGGGTGCTGCCCTGTCCATGCGCGCGGTAAC
CGGCAAACCGATCAAATTCGTCGGTCTTGGCGAAAAGATGGACGCGCTCGAAACCTTCGAGCCGGACCGCGTGGCAGGCC
GCATCCTCGGCATGGGCGACATCGTTGCGCTTGTCGAAAAAGCGCAGGAAACGCTCGAACTTGAGCAATCCGAGAAAATG
GTCAAACGCATGATGAAGGGTCACTTCACCATGAACGATTTGCGCATGCAGCTTGAACAGATGCAGAAAATGGGCGGCAT
GCAGGGCATGATGGGCATGATGCCCGGCATGGGTAAAATGGCCAAACAGGTCGAGGATGCAGGCTTTGACGACAATATCC
TCAAACGCCAGATCGCGCTGATCCAGTCGATGACCAAGAAAGAACGCGCCAACCCACAAATCCTGCAGGCCAGCCGCAAA
AAGCGGATCGCCAAGGGCGCGGGGCTGGAAGTCTCCGAACTGAACAAACTGCTCAAGATGCACCGCCAGATGGGCGACAT
GATGAAAAAGATGGGCAAGATGGGCAAGGGCGGCATGATGAAACAGGCCATGAAAGGCATGTTCGGCGGCAAAGGTATGG
GGGGCGGCCCCTCACCACAGGACATGGCCGCAGGCATGGACCCCAAAGCGCTCGAAGCTGCCGCAAAGCAATTGGGCGGC
GGCATGCCCGGTCAGAACCCGTTCGGCGGCGGCGCGGCCCTGCCCCCCGGCCTGTCAGGTTTCGGCAAAAAGAAATGA

Upstream 100 bases:

>100_bases
GGTTTTGTCCCATCGCAATGACACCGGGCGTTTGTGAAATGCACGCAGGTTGCCTACATCAGGGGCATCCTGCAACCGAA
ACCAAAGGGGGCCATGGCCC

Downstream 100 bases:

>100_bases
TGCACGCGGGCGATCATACGCTTGTGCAGATTCCGACCGTGCGCACGGAGCGATTCGTGCTGCGCGCGCCGAGGCGCTCG
GATCTTGACGCCTACACTGC

Product: signal recognition particle protein, putative

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MFENLSERLSGVFDRLTKQGALSEEDVKTALREVRVALLEADVSLPVARDFVKAVQEKATGQAVTKSITPGQQVVKIVHD
ALIDVLKGEGEPGTLKVDNPPASVLMVGLQGSGKTTTTAKLAKRLKEKDGKRVLMASLDVNRPAAMEQLAILGAQIGVDT
LPIIAGQDPVAIAKRAKTQAGLGGYDVYMLDTAGRLSIDEELMQQVEAVRDVASPRETLLVVDGLTGQDAVHTAQNFDER
IGISGVVLTRMDGDGRGGAALSMRAVTGKPIKFVGLGEKMDALETFEPDRVAGRILGMGDIVALVEKAQETLELEQSEKM
VKRMMKGHFTMNDLRMQLEQMQKMGGMQGMMGMMPGMGKMAKQVEDAGFDDNILKRQIALIQSMTKKERANPQILQASRK
KRIAKGAGLEVSELNKLLKMHRQMGDMMKKMGKMGKGGMMKQAMKGMFGGKGMGGGPSPQDMAAGMDPKALEAAAKQLGG
GMPGQNPFGGGAALPPGLSGFGKKK

Sequences:

>Translated_505_residues
MFENLSERLSGVFDRLTKQGALSEEDVKTALREVRVALLEADVSLPVARDFVKAVQEKATGQAVTKSITPGQQVVKIVHD
ALIDVLKGEGEPGTLKVDNPPASVLMVGLQGSGKTTTTAKLAKRLKEKDGKRVLMASLDVNRPAAMEQLAILGAQIGVDT
LPIIAGQDPVAIAKRAKTQAGLGGYDVYMLDTAGRLSIDEELMQQVEAVRDVASPRETLLVVDGLTGQDAVHTAQNFDER
IGISGVVLTRMDGDGRGGAALSMRAVTGKPIKFVGLGEKMDALETFEPDRVAGRILGMGDIVALVEKAQETLELEQSEKM
VKRMMKGHFTMNDLRMQLEQMQKMGGMQGMMGMMPGMGKMAKQVEDAGFDDNILKRQIALIQSMTKKERANPQILQASRK
KRIAKGAGLEVSELNKLLKMHRQMGDMMKKMGKMGKGGMMKQAMKGMFGGKGMGGGPSPQDMAAGMDPKALEAAAKQLGG
GMPGQNPFGGGAALPPGLSGFGKKK
>Mature_505_residues
MFENLSERLSGVFDRLTKQGALSEEDVKTALREVRVALLEADVSLPVARDFVKAVQEKATGQAVTKSITPGQQVVKIVHD
ALIDVLKGEGEPGTLKVDNPPASVLMVGLQGSGKTTTTAKLAKRLKEKDGKRVLMASLDVNRPAAMEQLAILGAQIGVDT
LPIIAGQDPVAIAKRAKTQAGLGGYDVYMLDTAGRLSIDEELMQQVEAVRDVASPRETLLVVDGLTGQDAVHTAQNFDER
IGISGVVLTRMDGDGRGGAALSMRAVTGKPIKFVGLGEKMDALETFEPDRVAGRILGMGDIVALVEKAQETLELEQSEKM
VKRMMKGHFTMNDLRMQLEQMQKMGGMQGMMGMMPGMGKMAKQVEDAGFDDNILKRQIALIQSMTKKERANPQILQASRK
KRIAKGAGLEVSELNKLLKMHRQMGDMMKKMGKMGKGGMMKQAMKGMFGGKGMGGGPSPQDMAAGMDPKALEAAAKQLGG
GMPGQNPFGGGAALPPGLSGFGKKK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=499, Percent_Identity=29.8597194388778, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI226371618, Length=395, Percent_Identity=31.3924050632911, Blast_Score=185, Evalue=7e-47,
Organism=Homo sapiens, GI89061728, Length=160, Percent_Identity=31.875, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI23308697, Length=306, Percent_Identity=28.7581699346405, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI295424842, Length=306, Percent_Identity=28.7581699346405, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1788963, Length=430, Percent_Identity=51.3953488372093, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1789874, Length=226, Percent_Identity=37.6106194690265, Blast_Score=135, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17539958, Length=494, Percent_Identity=28.7449392712551, Blast_Score=208, Evalue=7e-54,
Organism=Caenorhabditis elegans, GI193206261, Length=300, Percent_Identity=29.6666666666667, Blast_Score=105, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6325345, Length=486, Percent_Identity=29.8353909465021, Blast_Score=193, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6320498, Length=316, Percent_Identity=27.2151898734177, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17647949, Length=502, Percent_Identity=29.6812749003984, Blast_Score=199, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24641198, Length=305, Percent_Identity=27.2131147540984, Blast_Score=96, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 53873; Mature: 53873

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.7 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.7 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFENLSERLSGVFDRLTKQGALSEEDVKTALREVRVALLEADVSLPVARDFVKAVQEKAT
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GQAVTKSITPGQQVVKIVHDALIDVLKGEGEPGTLKVDNPPASVLMVGLQGSGKTTTTAK
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEECCCCCCHHHHH
LAKRLKEKDGKRVLMASLDVNRPAAMEQLAILGAQIGVDTLPIIAGQDPVAIAKRAKTQA
HHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHC
GLGGYDVYMLDTAGRLSIDEELMQQVEAVRDVASPRETLLVVDGLTGQDAVHTAQNFDER
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHH
IGISGVVLTRMDGDGRGGAALSMRAVTGKPIKFVGLGEKMDALETFEPDRVAGRILGMGD
CCCCEEEEEEECCCCCCCCEEEEEECCCCCEEEEECCCHHHHHHCCCCHHHHHHHHCHHH
IVALVEKAQETLELEQSEKMVKRMMKGHFTMNDLRMQLEQMQKMGGMQGMMGMMPGMGKM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCHHHH
AKQVEDAGFDDNILKRQIALIQSMTKKERANPQILQASRKKRIAKGAGLEVSELNKLLKM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
HRQMGDMMKKMGKMGKGGMMKQAMKGMFGGKGMGGGPSPQDMAAGMDPKALEAAAKQLGG
HHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCC
GMPGQNPFGGGAALPPGLSGFGKKK
CCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFENLSERLSGVFDRLTKQGALSEEDVKTALREVRVALLEADVSLPVARDFVKAVQEKAT
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GQAVTKSITPGQQVVKIVHDALIDVLKGEGEPGTLKVDNPPASVLMVGLQGSGKTTTTAK
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEECCCCCCHHHHH
LAKRLKEKDGKRVLMASLDVNRPAAMEQLAILGAQIGVDTLPIIAGQDPVAIAKRAKTQA
HHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHC
GLGGYDVYMLDTAGRLSIDEELMQQVEAVRDVASPRETLLVVDGLTGQDAVHTAQNFDER
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHH
IGISGVVLTRMDGDGRGGAALSMRAVTGKPIKFVGLGEKMDALETFEPDRVAGRILGMGD
CCCCEEEEEEECCCCCCCCEEEEEECCCCCEEEEECCCHHHHHHCCCCHHHHHHHHCHHH
IVALVEKAQETLELEQSEKMVKRMMKGHFTMNDLRMQLEQMQKMGGMQGMMGMMPGMGKM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCHHHH
AKQVEDAGFDDNILKRQIALIQSMTKKERANPQILQASRKKRIAKGAGLEVSELNKLLKM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
HRQMGDMMKKMGKMGKGGMMKQAMKGMFGGKGMGGGPSPQDMAAGMDPKALEAAAKQLGG
HHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCC
GMPGQNPFGGGAALPPGLSGFGKKK
CCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]