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The map label for this gene is frpC [H]

Identifier: 110678501

GI number: 110678501

Start: 1134060

End: 1135694

Strand: Reverse

Name: frpC [H]

Synonym: RD1_1171

Alternate gene names: 110678501

Gene position: 1135694-1134060 (Counterclockwise)

Preceding gene: 110678502

Following gene: 110678499

Centisome position: 27.48

GC content: 59.88

Gene sequence:

>1635_bases
GTGACCAACTTTGCGCCAGAGTCGTTTGTGAACTTCGAGAATGTCGTGACCGGCAACGGGAATACCACGATCACCGGGAC
GGCCGGTGCGAATGTCATTACCACTGGAAACGGAAACGACACGGTAAATGCCGGATCGGGCAATGACACGATCAACACTG
GCAGCGGTGATGACACGGTCAACGGCGGCAGTGGCAATGACACGATCAACACTGGCGCGGGCAACGACACGGTAGAGTCC
AGTACAGGGTCCGATACGATCTTTCTGGGCGATGGCGATGATACAGCCACCTCCTCGGGGACGGATACGATCTTTGGCGG
CGCCGGCAATGATCTGATCTTTTCGGGTCTTGGCCTGCCCGAAACGCTGGATGGCGGCAACGGGATCGACACGCTGAACA
CCACGAGTTTCAGCGGTTCCTATGTCGTCAACCTCGCAACCGGTCTGACAAATTTCGCAGGCGAGGTCTTCACCAACTTC
GAGAATATCATTTCCGGCAGTGGCAGTGATGAACTGTTCGGCACAAGCGGCGTCAACATCATGGAAGGGGGCGACGGCAA
CGACCGGATTCTCGGGCTTGAGGGCAGCGACACCCTGCGTGGGGGCGGCGGCAATGACGTTCTGAACGGCGGATTGGGCA
ACGACATCCTGCGTGGTGACGCCAATGAGGACCGCCTCTTCGGACGCGAAGGCGACGACAACCTCGATGGTGGATCAGGG
GATGACCTGCTCGTCGGCAATGAAGGCAACGATATCCTGAACGGCAGCGGCGGGGATGACTTTATCCGCGGTCAAGCCGG
GGTCGATTTCATCAACGGCGGCGACGGAAACGATGAAGCCTTTGGCGGTGATGGGAATGACACCATGCGCGGCGGTGAAG
GTGACGACCTGCTCGACGGCAGCGCTGGTAACGATTTCATCGACGGGGAGGACGGCAACGATGTCCTTGTCGGTCAGATC
GGCAATGACACATTGCTTGGCGGCGACGGGTCGGATGAGTTGCGCGGCGGCGGCGGCAATGATTTCCTGAACGGAGAAAA
CGGCAATGACACGCTGTTTGGTGGCGCCAATGAGGACACGTTGTTCGGCGGTTCTGGCGATGACTTCCTGCAGGGCAACC
AGCAGGACGATGATCTCTTTGGCCAGTCCGGCAATGACCGCTTGTTCGGCGGTGATGGTTTTGACTTCTTGGATGGCGGC
ATCGGTGATGACCGGCTTGAGGGCAACAACGGGCGCGATACGCTGGTGGGCGGCACGGGCGCGGATATCCTCATCGGCGG
GGCCTTGGGCGACACGTTCCGGTTCAACAGTGTGGCGGATTCCAACCTTGCCAGCAGAGACACGATTGTCGGCATCGATG
GCATCGGCGTGGCCAATGGCGACGTGATCGACGTCTCCGTCATCGACGCGAACACCACAATCGGTGGCAATCAGGCCTTC
ACCTTCCTCGGGTTGCAGACGACCGCATCGGCCCTGTCCTTTGGCGCAGGCGCGCTTTGGGTCGAGAACGCGGGAGGGCC
AACCCTGCTGTTCGGGAACATCGACAACGACGCCACGATCGAGTTCGCCGTCCAGATCAACGACGGTGCGGGCACCTCGG
CGGCAGATTACACCTTGGGTGACTTCATCGTCTGA

Upstream 100 bases:

>100_bases
CAGCAACACCGCCTTTGAAACACTCGACGGCGGTGCGGGCATCGATACGCTGAACACCACGCTGTTCAATGGCACCTATG
AAATCAACCTCGTCACAGGC

Downstream 100 bases:

>100_bases
AGCACGCCCTTGACCTGAAAAACCACCACGCGCCGCTCAACACAGAGCCCGCGTGGTGGGCACCAAAGGCCCGCGACCTA
CGCCGGCCACTTTTCTTTCG

Product: type I secretion target repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MTNFAPESFVNFENVVTGNGNTTITGTAGANVITTGNGNDTVNAGSGNDTINTGSGDDTVNGGSGNDTINTGAGNDTVES
STGSDTIFLGDGDDTATSSGTDTIFGGAGNDLIFSGLGLPETLDGGNGIDTLNTTSFSGSYVVNLATGLTNFAGEVFTNF
ENIISGSGSDELFGTSGVNIMEGGDGNDRILGLEGSDTLRGGGGNDVLNGGLGNDILRGDANEDRLFGREGDDNLDGGSG
DDLLVGNEGNDILNGSGGDDFIRGQAGVDFINGGDGNDEAFGGDGNDTMRGGEGDDLLDGSAGNDFIDGEDGNDVLVGQI
GNDTLLGGDGSDELRGGGGNDFLNGENGNDTLFGGANEDTLFGGSGDDFLQGNQQDDDLFGQSGNDRLFGGDGFDFLDGG
IGDDRLEGNNGRDTLVGGTGADILIGGALGDTFRFNSVADSNLASRDTIVGIDGIGVANGDVIDVSVIDANTTIGGNQAF
TFLGLQTTASALSFGAGALWVENAGGPTLLFGNIDNDATIEFAVQINDGAGTSAADYTLGDFIV

Sequences:

>Translated_544_residues
MTNFAPESFVNFENVVTGNGNTTITGTAGANVITTGNGNDTVNAGSGNDTINTGSGDDTVNGGSGNDTINTGAGNDTVES
STGSDTIFLGDGDDTATSSGTDTIFGGAGNDLIFSGLGLPETLDGGNGIDTLNTTSFSGSYVVNLATGLTNFAGEVFTNF
ENIISGSGSDELFGTSGVNIMEGGDGNDRILGLEGSDTLRGGGGNDVLNGGLGNDILRGDANEDRLFGREGDDNLDGGSG
DDLLVGNEGNDILNGSGGDDFIRGQAGVDFINGGDGNDEAFGGDGNDTMRGGEGDDLLDGSAGNDFIDGEDGNDVLVGQI
GNDTLLGGDGSDELRGGGGNDFLNGENGNDTLFGGANEDTLFGGSGDDFLQGNQQDDDLFGQSGNDRLFGGDGFDFLDGG
IGDDRLEGNNGRDTLVGGTGADILIGGALGDTFRFNSVADSNLASRDTIVGIDGIGVANGDVIDVSVIDANTTIGGNQAF
TFLGLQTTASALSFGAGALWVENAGGPTLLFGNIDNDATIEFAVQINDGAGTSAADYTLGDFIV
>Mature_543_residues
TNFAPESFVNFENVVTGNGNTTITGTAGANVITTGNGNDTVNAGSGNDTINTGSGDDTVNGGSGNDTINTGAGNDTVESS
TGSDTIFLGDGDDTATSSGTDTIFGGAGNDLIFSGLGLPETLDGGNGIDTLNTTSFSGSYVVNLATGLTNFAGEVFTNFE
NIISGSGSDELFGTSGVNIMEGGDGNDRILGLEGSDTLRGGGGNDVLNGGLGNDILRGDANEDRLFGREGDDNLDGGSGD
DLLVGNEGNDILNGSGGDDFIRGQAGVDFINGGDGNDEAFGGDGNDTMRGGEGDDLLDGSAGNDFIDGEDGNDVLVGQIG
NDTLLGGDGSDELRGGGGNDFLNGENGNDTLFGGANEDTLFGGSGDDFLQGNQQDDDLFGQSGNDRLFGGDGFDFLDGGI
GDDRLEGNNGRDTLVGGTGADILIGGALGDTFRFNSVADSNLASRDTIVGIDGIGVANGDVIDVSVIDANTTIGGNQAFT
FLGLQTTASALSFGAGALWVENAGGPTLLFGNIDNDATIEFAVQINDGAGTSAADYTLGDFIV

Specific function: May participate in the pathogenesis of meningococcal disease [H]

COG id: COG2931

COG function: function code Q; RTX toxins and related Ca2+-binding proteins

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Secreted (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 22 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010566
- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF06594 HCBP_related; PF00353 HemolysinCabind [H]

EC number: NA

Molecular weight: Translated: 54291; Mature: 54159

Theoretical pI: Translated: 3.17; Mature: 3.17

Prosite motif: PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNFAPESFVNFENVVTGNGNTTITGTAGANVITTGNGNDTVNAGSGNDTINTGSGDDTV
CCCCCCHHHCCCCEEEECCCCEEEEECCCCEEEEECCCCCEEECCCCCCCEECCCCCCCC
NGGSGNDTINTGAGNDTVESSTGSDTIFLGDGDDTATSSGTDTIFGGAGNDLIFSGLGLP
CCCCCCCCEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEECCCCCCEEEECCCCC
ETLDGGNGIDTLNTTSFSGSYVVNLATGLTNFAGEVFTNFENIISGSGSDELFGTSGVNI
CCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEE
MEGGDGNDRILGLEGSDTLRGGGGNDVLNGGLGNDILRGDANEDRLFGREGDDNLDGGSG
EECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCEECCCCCCCCCCCCC
DDLLVGNEGNDILNGSGGDDFIRGQAGVDFINGGDGNDEAFGGDGNDTMRGGEGDDLLDG
CEEEECCCCCCCCCCCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
SAGNDFIDGEDGNDVLVGQIGNDTLLGGDGSDELRGGGGNDFLNGENGNDTLFGGANEDT
CCCCCCCCCCCCCEEEEEECCCCEEECCCCCHHCCCCCCCCCCCCCCCCCCEECCCCCCE
LFGGSGDDFLQGNQQDDDLFGQSGNDRLFGGDGFDFLDGGIGDDRLEGNNGRDTLVGGTG
EECCCCCHHHCCCCCCHHHCCCCCCCEEECCCCCHHHCCCCCCCCCCCCCCCEEEECCCC
ADILIGGALGDTFRFNSVADSNLASRDTIVGIDGIGVANGDVIDVSVIDANTTIGGNQAF
CCEEEECCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCEECCCCEE
TFLGLQTTASALSFGAGALWVENAGGPTLLFGNIDNDATIEFAVQINDGAGTSAADYTLG
EEEEEHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCC
DFIV
CCCC
>Mature Secondary Structure 
TNFAPESFVNFENVVTGNGNTTITGTAGANVITTGNGNDTVNAGSGNDTINTGSGDDTV
CCCCCHHHCCCCEEEECCCCEEEEECCCCEEEEECCCCCEEECCCCCCCEECCCCCCCC
NGGSGNDTINTGAGNDTVESSTGSDTIFLGDGDDTATSSGTDTIFGGAGNDLIFSGLGLP
CCCCCCCCEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEECCCCCCEEEECCCCC
ETLDGGNGIDTLNTTSFSGSYVVNLATGLTNFAGEVFTNFENIISGSGSDELFGTSGVNI
CCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEE
MEGGDGNDRILGLEGSDTLRGGGGNDVLNGGLGNDILRGDANEDRLFGREGDDNLDGGSG
EECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCEECCCCCCCCCCCCC
DDLLVGNEGNDILNGSGGDDFIRGQAGVDFINGGDGNDEAFGGDGNDTMRGGEGDDLLDG
CEEEECCCCCCCCCCCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
SAGNDFIDGEDGNDVLVGQIGNDTLLGGDGSDELRGGGGNDFLNGENGNDTLFGGANEDT
CCCCCCCCCCCCCEEEEEECCCCEEECCCCCHHCCCCCCCCCCCCCCCCCCEECCCCCCE
LFGGSGDDFLQGNQQDDDLFGQSGNDRLFGGDGFDFLDGGIGDDRLEGNNGRDTLVGGTG
EECCCCCHHHCCCCCCHHHCCCCCCCEEECCCCCHHHCCCCCCCCCCCCCCCEEEECCCC
ADILIGGALGDTFRFNSVADSNLASRDTIVGIDGIGVANGDVIDVSVIDANTTIGGNQAF
CCEEEECCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCEECCCCEE
TFLGLQTTASALSFGAGALWVENAGGPTLLFGNIDNDATIEFAVQINDGAGTSAADYTLG
EEEEEHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCC
DFIV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]