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The map label for this gene is appC [H]

Identifier: 110678435

GI number: 110678435

Start: 1050004

End: 1051158

Strand: Reverse

Name: appC [H]

Synonym: RD1_1099

Alternate gene names: 110678435

Gene position: 1051158-1050004 (Counterclockwise)

Preceding gene: 110678436

Following gene: 110678434

Centisome position: 25.43

GC content: 58.79

Gene sequence:

>1155_bases
ATGACAAGAATGCCAGACGGTCGCTATGTCGACGACGCCCCCTATACCGATGATGTGGACCTCAGCGCGCTTGAACGCTC
TGATATGGATGCGCCGAACTGGGTGCTGGTTTGGCGCAAATTCAAACGGCACAGGCTGGGTCTGATATCTGGGATATTCC
TGCTGCTTAGCTACATGATGCTGCCCTTTGCGGGCTTTATCGCGCCCTACACACCGAATGAGCGCAGCGCGGATTACCTT
TATGCGCCGCCACAATCCATCAACCTGTGGCACGACGGGCGCTTCATCGGGCCTTATGTCTATCCGATCACTGCCACGGC
GGATCTGGTCAATTACCGCTGGACCTATGAAACCGATACCAGCACACCCATGCCGCTGGAATTCTTTTGTGAAGGACAGC
AATACAGGCTCGCGGGCTTTATCCCGTCCAATACCCATCTGTTTTGCGCAGCCGATGGGGCGACCGTGTTTCTCTGGGGG
TCGGACAGGTTGGGGCGTGACGTGTTCAGCCGCATTCTCTACGGCGCACAACTGTCCCTGACCGTGGGTCTGATCGGGAT
CACCGTTTCCTTTGTGCTGGGCATCTTCTTTGGGTCGATTGCGGGATACTTCGGGGGGCGCACGGATTGGATCATCAACC
GCATGATCGAAATCCTGAGATCCCTGCCGGAACTGCCGTTGTGGCTGGCGCTATCGGCCGCGGTTCCGTCGAACTGGAGC
CCGGTGTCGGTCTTTTTCATCATCTCGATCATTCTGGGGATATTGGATTGGCCGGGGCTGGCGCGGGCGGTGCGATCCAA
ATTCCTGTCCCTGCGTGAAGAGGAATACGTGCGCGCCGCCGAGATGATGGGGGCCAAGCCGGGGCGCGTGATCCGCCGCC
ATCTCTTGCCGAACTTCATGTCGCATCTGATCGCTTCGGCAACGCTCTCCATTCCGGCGATGATCCTTGGCGAAACCGCG
CTCAGCTTTCTGGGGCTGGGCTTGCGCGCGCCTGCGGTCAGTTGGGGTGTCATGCTGAATGACGCGCAAAACCTCGCGTC
GATCGAGATCTACCCATGGACTGCCATCCCGATGCTGCCGATCATCTTTGTGGTGCTGGCGTTCAACTTCCTCGGCGACG
GCCTGCGCGCCTCTCTGGACCCCTATAGGGGATAA

Upstream 100 bases:

>100_bases
TCCTGATGTTCGTGGCCCTGCTGACCCTGATCGGCACGATGGTGTCTGATCTGTTGCTGGTGCTGCTGGATCCGCGCATC
AGATACGGGGCGCGCGGGCG

Downstream 100 bases:

>100_bases
TGCGGTCCTGTGCTTCGCCTTGATGACCTGTTTAAGGGCTGCGTTGACCTGTTCAGCACACAACCTGAAATCGTTTCCCA
GCATCTCAAGACTAAAGCTG

Product: oligopeptide ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MTRMPDGRYVDDAPYTDDVDLSALERSDMDAPNWVLVWRKFKRHRLGLISGIFLLLSYMMLPFAGFIAPYTPNERSADYL
YAPPQSINLWHDGRFIGPYVYPITATADLVNYRWTYETDTSTPMPLEFFCEGQQYRLAGFIPSNTHLFCAADGATVFLWG
SDRLGRDVFSRILYGAQLSLTVGLIGITVSFVLGIFFGSIAGYFGGRTDWIINRMIEILRSLPELPLWLALSAAVPSNWS
PVSVFFIISIILGILDWPGLARAVRSKFLSLREEEYVRAAEMMGAKPGRVIRRHLLPNFMSHLIASATLSIPAMILGETA
LSFLGLGLRAPAVSWGVMLNDAQNLASIEIYPWTAIPMLPIIFVVLAFNFLGDGLRASLDPYRG

Sequences:

>Translated_384_residues
MTRMPDGRYVDDAPYTDDVDLSALERSDMDAPNWVLVWRKFKRHRLGLISGIFLLLSYMMLPFAGFIAPYTPNERSADYL
YAPPQSINLWHDGRFIGPYVYPITATADLVNYRWTYETDTSTPMPLEFFCEGQQYRLAGFIPSNTHLFCAADGATVFLWG
SDRLGRDVFSRILYGAQLSLTVGLIGITVSFVLGIFFGSIAGYFGGRTDWIINRMIEILRSLPELPLWLALSAAVPSNWS
PVSVFFIISIILGILDWPGLARAVRSKFLSLREEEYVRAAEMMGAKPGRVIRRHLLPNFMSHLIASATLSIPAMILGETA
LSFLGLGLRAPAVSWGVMLNDAQNLASIEIYPWTAIPMLPIIFVVLAFNFLGDGLRASLDPYRG
>Mature_383_residues
TRMPDGRYVDDAPYTDDVDLSALERSDMDAPNWVLVWRKFKRHRLGLISGIFLLLSYMMLPFAGFIAPYTPNERSADYLY
APPQSINLWHDGRFIGPYVYPITATADLVNYRWTYETDTSTPMPLEFFCEGQQYRLAGFIPSNTHLFCAADGATVFLWGS
DRLGRDVFSRILYGAQLSLTVGLIGITVSFVLGIFFGSIAGYFGGRTDWIINRMIEILRSLPELPLWLALSAAVPSNWSP
VSVFFIISIILGILDWPGLARAVRSKFLSLREEEYVRAAEMMGAKPGRVIRRHLLPNFMSHLIASATLSIPAMILGETAL
SFLGLGLRAPAVSWGVMLNDAQNLASIEIYPWTAIPMLPIIFVVLAFNFLGDGLRASLDPYRG

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=224, Percent_Identity=39.2857142857143, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787760, Length=227, Percent_Identity=36.1233480176211, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1787498, Length=224, Percent_Identity=37.5, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1789889, Length=228, Percent_Identity=36.8421052631579, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789964, Length=230, Percent_Identity=39.5652173913043, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1788505, Length=226, Percent_Identity=33.1858407079646, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1787549, Length=228, Percent_Identity=32.0175438596491, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 42941; Mature: 42810

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRMPDGRYVDDAPYTDDVDLSALERSDMDAPNWVLVWRKFKRHRLGLISGIFLLLSYMM
CCCCCCCCEECCCCCCCCCCHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
LPFAGFIAPYTPNERSADYLYAPPQSINLWHDGRFIGPYVYPITATADLVNYRWTYETDT
HHHHHHCCCCCCCCCCCCEEECCCCCCEEEECCEEECCEEEEEEEEEEHHEEEEEEECCC
STPMPLEFFCEGQQYRLAGFIPSNTHLFCAADGATVFLWGSDRLGRDVFSRILYGAQLSL
CCCCCHHEEECCCEEEEEEECCCCCEEEEEECCCEEEEECCCCCCHHHHHHHHHCCHHHH
TVGLIGITVSFVLGIFFGSIAGYFGGRTDWIINRMIEILRSLPELPLWLALSAAVPSNWS
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHEEECCCCCCCC
PVSVFFIISIILGILDWPGLARAVRSKFLSLREEEYVRAAEMMGAKPGRVIRRHLLPNFM
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SHLIASATLSIPAMILGETALSFLGLGLRAPAVSWGVMLNDAQNLASIEIYPWTAIPMLP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEECCCCCCEEEEEECCCHHHHHH
IIFVVLAFNFLGDGLRASLDPYRG
HHHHHHHHHHHCCCHHCCCCCCCC
>Mature Secondary Structure 
TRMPDGRYVDDAPYTDDVDLSALERSDMDAPNWVLVWRKFKRHRLGLISGIFLLLSYMM
CCCCCCCEECCCCCCCCCCHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
LPFAGFIAPYTPNERSADYLYAPPQSINLWHDGRFIGPYVYPITATADLVNYRWTYETDT
HHHHHHCCCCCCCCCCCCEEECCCCCCEEEECCEEECCEEEEEEEEEEHHEEEEEEECCC
STPMPLEFFCEGQQYRLAGFIPSNTHLFCAADGATVFLWGSDRLGRDVFSRILYGAQLSL
CCCCCHHEEECCCEEEEEEECCCCCEEEEEECCCEEEEECCCCCCHHHHHHHHHCCHHHH
TVGLIGITVSFVLGIFFGSIAGYFGGRTDWIINRMIEILRSLPELPLWLALSAAVPSNWS
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHEEECCCCCCCC
PVSVFFIISIILGILDWPGLARAVRSKFLSLREEEYVRAAEMMGAKPGRVIRRHLLPNFM
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SHLIASATLSIPAMILGETALSFLGLGLRAPAVSWGVMLNDAQNLASIEIYPWTAIPMLP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEECCCCCCEEEEEECCCHHHHHH
IIFVVLAFNFLGDGLRASLDPYRG
HHHHHHHHHHHCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]