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The map label for this gene is qor [H]

Identifier: 110678383

GI number: 110678383

Start: 1004749

End: 1005723

Strand: Direct

Name: qor [H]

Synonym: RD1_1041

Alternate gene names: 110678383

Gene position: 1004749-1005723 (Clockwise)

Preceding gene: 110678382

Following gene: 110678385

Centisome position: 24.31

GC content: 61.74

Gene sequence:

>975_bases
ATGGTAAAGACCGTAATCATTGAAGAAGCCGGTGGGCCTGAGGCTCTGCGCGTGGTGGATCGACCCGTTGGTGATCCGGG
GGCCGGTGAGGTGCGCATCACCCACAAGGCCTGCGGTTTGAATTTCATCGACGTCTATCAACGCAGTGGCCTTTACCCGA
TGACGTTGCCCCATGCCCTCGGGATGGAAGCGGCGGGCGTGATCGAGGCTGTCGGCGCAGGAGTCACGCATCTGAAGGTT
GGCGACCGCGCCGCCTATGCCGCCACCCCGCCCGGTGCTTATGCGCAGGCCCGCGTGATGCCCGCCGCACAGGTTTGCCC
GTTGCCTGATGGGATTTCGTTCGAAGAAGCCGCCGCCATGATGCTCAAAGGGCTGACGGTGCAGTATCTGTTCCACCGCA
CGACCCCGCTGAAGGTGGGCGACACCGTGTTGTTTCACGCGGCCGCCGGGGGTGTTGGTCTGATTGCCTGCCAATGGGCG
CGCTCAGAAGGGATCACGCTGATCGGGACTGCCGGGAGCGATGCAAAATGTGCGATGGCGCTGGAGCACGGTGCCGCCCA
TTGCATCAACTACAAAACCGAGGATTTCGCCGCGCGGGTCCGCGCGCTTACCGATGGCAAGGGCGTAGACGTGGTGATGG
ATGCGGTCGGCGCGGATACCTTTGAGGGGTCATTGGACAGCCTCAAGCCGCTTGGCATGATGATTTCCTTTGGGAATGCG
TCGGGGCCGGTGCCGCCGTTTTCTGTCGGTATTCTGGGCCAGAAAGGGTCACTGAAAATCACCCGCCCGACCCTGTTCAC
CCATATCGCAGAGCATGAAACCTGTCAGGCCATGGCGGCACAGCTGTTTGGAAAGGTGCAAAGCGGAGCGGTGAAGATTC
GCATCGACCAGCGATTTGCGCTCGATGATGTGGCTGAGGCCCATCGCGCGCTGGAAGCACGCAAAACCACGGGCAGCACG
ATTCTGACGCCCTAG

Upstream 100 bases:

>100_bases
GCGGCGCATACACGCATGGAAAGCTCGGGCCATATTGGCAAGATCGTTCTGAAAGTCGCCTCGTGAGGCCCGTGCCAGTT
CGACGTAGTGGAGGGATAAG

Downstream 100 bases:

>100_bases
CGGACCGGGGTGAACAGCGCGTTTTTCGCGCTACAGTCCCGGATGACATCGCGCCCGCACTGGCGCGGCTCAAGCGCGCG
GGTCAGGCAAACCCGTGCCT

Product: quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MVKTVIIEEAGGPEALRVVDRPVGDPGAGEVRITHKACGLNFIDVYQRSGLYPMTLPHALGMEAAGVIEAVGAGVTHLKV
GDRAAYAATPPGAYAQARVMPAAQVCPLPDGISFEEAAAMMLKGLTVQYLFHRTTPLKVGDTVLFHAAAGGVGLIACQWA
RSEGITLIGTAGSDAKCAMALEHGAAHCINYKTEDFAARVRALTDGKGVDVVMDAVGADTFEGSLDSLKPLGMMISFGNA
SGPVPPFSVGILGQKGSLKITRPTLFTHIAEHETCQAMAAQLFGKVQSGAVKIRIDQRFALDDVAEAHRALEARKTTGST
ILTP

Sequences:

>Translated_324_residues
MVKTVIIEEAGGPEALRVVDRPVGDPGAGEVRITHKACGLNFIDVYQRSGLYPMTLPHALGMEAAGVIEAVGAGVTHLKV
GDRAAYAATPPGAYAQARVMPAAQVCPLPDGISFEEAAAMMLKGLTVQYLFHRTTPLKVGDTVLFHAAAGGVGLIACQWA
RSEGITLIGTAGSDAKCAMALEHGAAHCINYKTEDFAARVRALTDGKGVDVVMDAVGADTFEGSLDSLKPLGMMISFGNA
SGPVPPFSVGILGQKGSLKITRPTLFTHIAEHETCQAMAAQLFGKVQSGAVKIRIDQRFALDDVAEAHRALEARKTTGST
ILTP
>Mature_324_residues
MVKTVIIEEAGGPEALRVVDRPVGDPGAGEVRITHKACGLNFIDVYQRSGLYPMTLPHALGMEAAGVIEAVGAGVTHLKV
GDRAAYAATPPGAYAQARVMPAAQVCPLPDGISFEEAAAMMLKGLTVQYLFHRTTPLKVGDTVLFHAAAGGVGLIACQWA
RSEGITLIGTAGSDAKCAMALEHGAAHCINYKTEDFAARVRALTDGKGVDVVMDAVGADTFEGSLDSLKPLGMMISFGNA
SGPVPPFSVGILGQKGSLKITRPTLFTHIAEHETCQAMAAQLFGKVQSGAVKIRIDQRFALDDVAEAHRALEARKTTGST
ILTP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI18379349, Length=316, Percent_Identity=32.9113924050633, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI22538446, Length=329, Percent_Identity=32.8267477203647, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI22538444, Length=329, Percent_Identity=32.8267477203647, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI194239674, Length=326, Percent_Identity=31.9018404907975, Blast_Score=148, Evalue=6e-36,
Organism=Homo sapiens, GI13236495, Length=326, Percent_Identity=31.9018404907975, Blast_Score=148, Evalue=6e-36,
Organism=Homo sapiens, GI194239676, Length=326, Percent_Identity=30.3680981595092, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI24308257, Length=342, Percent_Identity=28.3625730994152, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI28557745, Length=226, Percent_Identity=32.7433628318584, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI197927207, Length=187, Percent_Identity=30.4812834224599, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI156627571, Length=242, Percent_Identity=28.5123966942149, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=48.0122324159021, Blast_Score=307, Evalue=5e-85,
Organism=Caenorhabditis elegans, GI17507255, Length=241, Percent_Identity=29.4605809128631, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319520, Length=324, Percent_Identity=40.1234567901235, Blast_Score=227, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6319955, Length=276, Percent_Identity=29.7101449275362, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6322619, Length=276, Percent_Identity=29.7101449275362, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6319621, Length=266, Percent_Identity=24.812030075188, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33832; Mature: 33832

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKTVIIEEAGGPEALRVVDRPVGDPGAGEVRITHKACGLNFIDVYQRSGLYPMTLPHAL
CCEEEEEECCCCCCEEHEECCCCCCCCCCCEEEEEHHCCCCHHHHHHHCCCCCEECCHHH
GMEAAGVIEAVGAGVTHLKVGDRAAYAATPPGAYAQARVMPAAQVCPLPDGISFEEAAAM
CCCHHHHHHHHCCCEEEEEECCCEEEECCCCCCCHHEEECCHHHCCCCCCCCCHHHHHHH
MLKGLTVQYLFHRTTPLKVGDTVLFHAAAGGVGLIACQWARSEGITLIGTAGSDAKCAMA
HHHCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEEEEECCCCEEEEEECCCCCEEEEE
LEHGAAHCINYKTEDFAARVRALTDGKGVDVVMDAVGADTFEGSLDSLKPLGMMISFGNA
ECCCCCEEECCCCHHHHHHHHHHCCCCCCEEEEHHHCCCCCCCCHHHCCCCEEEEEECCC
SGPVPPFSVGILGQKGSLKITRPTLFTHIAEHETCQAMAAQLFGKVQSGAVKIRIDQRFA
CCCCCCCEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
LDDVAEAHRALEARKTTGSTILTP
HHHHHHHHHHHHHHCCCCCEECCC
>Mature Secondary Structure
MVKTVIIEEAGGPEALRVVDRPVGDPGAGEVRITHKACGLNFIDVYQRSGLYPMTLPHAL
CCEEEEEECCCCCCEEHEECCCCCCCCCCCEEEEEHHCCCCHHHHHHHCCCCCEECCHHH
GMEAAGVIEAVGAGVTHLKVGDRAAYAATPPGAYAQARVMPAAQVCPLPDGISFEEAAAM
CCCHHHHHHHHCCCEEEEEECCCEEEECCCCCCCHHEEECCHHHCCCCCCCCCHHHHHHH
MLKGLTVQYLFHRTTPLKVGDTVLFHAAAGGVGLIACQWARSEGITLIGTAGSDAKCAMA
HHHCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEEEEECCCCEEEEEECCCCCEEEEE
LEHGAAHCINYKTEDFAARVRALTDGKGVDVVMDAVGADTFEGSLDSLKPLGMMISFGNA
ECCCCCEEECCCCHHHHHHHHHHCCCCCCEEEEHHHCCCCCCCCHHHCCCCEEEEEECCC
SGPVPPFSVGILGQKGSLKITRPTLFTHIAEHETCQAMAAQLFGKVQSGAVKIRIDQRFA
CCCCCCCEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
LDDVAEAHRALEARKTTGSTILTP
HHHHHHHHHHHHHHCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]