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The map label for this gene is map [H]

Identifier: 110678296

GI number: 110678296

Start: 917647

End: 918531

Strand: Reverse

Name: map [H]

Synonym: RD1_0949

Alternate gene names: 110678296

Gene position: 918531-917647 (Counterclockwise)

Preceding gene: 110678297

Following gene: 110678293

Centisome position: 22.22

GC content: 58.53

Gene sequence:

>885_bases
ATGGAGACGCAGGTGAACCAAGACCTCAAAGGCCGCCAGACCAAGGACGGCATCAGGATATACGACGCCGCAGATTTCGC
CGGCATGCGCAAGGCCGGTGCGCTGACGGCGCGTATATTGGATGACATTGCCGATCTTGTTTTCGTCGGGCAGACAACGG
GTGCCATCGACAAAAGGATCGAAGAGATGGTCGAAGAGGCGGGCGCCACCTCGGCCACGATCAATTACAAGGGTTACAAA
CACGCCAGCTGCATTTCGGTCAACAGTGTCGTCTGCCATGGCATTCCCGGCGCGCCGATCCCGAAAAGCGGCAGCGAGAC
GATCTCCAAGGATCCCGAAAAGCGCCGCGATGACGATGTGCTGCGCGATGGCGACATCCTGAACATCGACGTCACTGCGA
TCGTGGATGGCTGGTTTGGTGATTCCAGCCGGATGTATGTGGCAGGCACCGCGCCGAAAAAGGCACAAAAGCTCATTCAG
GTGACACATGACGCGCTGATGCGCGGCATCGAAGCGGTCAAACCCGGCAACACCTTTGGTGATATCGGATATGCCATCCA
GAGTTTCGTGGAAAGCAACCGCATGTCAGTCGTGCGCGATTTCTGCGGTCATGGGTTGGGGCGTGTGTTTCATGCACCGC
CCAATGTGTTGCACTATGGCCGACCCGGCACCGGCGCGGTTCTGGAAGAAGGCATGTTCTTTACCATCGAGCCGATGGTC
AATCTGGGGCGGCCCGAAACGAAAACGCTGGCCGACGACTGGACCGCCGTGACACGGGACAAAACACTCTCTGCGCAGTT
CGAACATTCCATCGGTGTGACGGCGGATGGTGCGGAGATCTTTACGCTGTCACCTGCCGGCAGGTTCCATCCGACGTCGG
GCTAG

Upstream 100 bases:

>100_bases
CGCCACAGGGCATTGAGGTCGCGGGCGCGATCCCCATTCGCCTGTGATGCGGTCTGGTTCTCGCACCCAAGGCGCGTTAG
AAGGCCGCTAAAGACGCACG

Downstream 100 bases:

>100_bases
GGGTCATCCGCGCGCTTTGAGACCTCTTTGCGCAGCAAGGCCAGCAACAGCGTTTCACCGCCCCAGGGCTGCACCGCATC
GCCGATAAACACCGGCCCGG

Product: methionine aminopeptidase, type I, putative

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
METQVNQDLKGRQTKDGIRIYDAADFAGMRKAGALTARILDDIADLVFVGQTTGAIDKRIEEMVEEAGATSATINYKGYK
HASCISVNSVVCHGIPGAPIPKSGSETISKDPEKRRDDDVLRDGDILNIDVTAIVDGWFGDSSRMYVAGTAPKKAQKLIQ
VTHDALMRGIEAVKPGNTFGDIGYAIQSFVESNRMSVVRDFCGHGLGRVFHAPPNVLHYGRPGTGAVLEEGMFFTIEPMV
NLGRPETKTLADDWTAVTRDKTLSAQFEHSIGVTADGAEIFTLSPAGRFHPTSG

Sequences:

>Translated_294_residues
METQVNQDLKGRQTKDGIRIYDAADFAGMRKAGALTARILDDIADLVFVGQTTGAIDKRIEEMVEEAGATSATINYKGYK
HASCISVNSVVCHGIPGAPIPKSGSETISKDPEKRRDDDVLRDGDILNIDVTAIVDGWFGDSSRMYVAGTAPKKAQKLIQ
VTHDALMRGIEAVKPGNTFGDIGYAIQSFVESNRMSVVRDFCGHGLGRVFHAPPNVLHYGRPGTGAVLEEGMFFTIEPMV
NLGRPETKTLADDWTAVTRDKTLSAQFEHSIGVTADGAEIFTLSPAGRFHPTSG
>Mature_294_residues
METQVNQDLKGRQTKDGIRIYDAADFAGMRKAGALTARILDDIADLVFVGQTTGAIDKRIEEMVEEAGATSATINYKGYK
HASCISVNSVVCHGIPGAPIPKSGSETISKDPEKRRDDDVLRDGDILNIDVTAIVDGWFGDSSRMYVAGTAPKKAQKLIQ
VTHDALMRGIEAVKPGNTFGDIGYAIQSFVESNRMSVVRDFCGHGLGRVFHAPPNVLHYGRPGTGAVLEEGMFFTIEPMV
NLGRPETKTLADDWTAVTRDKTLSAQFEHSIGVTADGAEIFTLSPAGRFHPTSG

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=280, Percent_Identity=37.1428571428571, Blast_Score=194, Evalue=6e-50,
Organism=Homo sapiens, GI40385867, Length=270, Percent_Identity=34.0740740740741, Blast_Score=164, Evalue=9e-41,
Organism=Escherichia coli, GI1786364, Length=268, Percent_Identity=45.1492537313433, Blast_Score=233, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI71996291, Length=277, Percent_Identity=36.4620938628159, Blast_Score=177, Evalue=7e-45,
Organism=Saccharomyces cerevisiae, GI6323273, Length=268, Percent_Identity=37.3134328358209, Blast_Score=189, Evalue=3e-49,
Organism=Drosophila melanogaster, GI21355531, Length=265, Percent_Identity=41.5094339622642, Blast_Score=211, Evalue=5e-55,
Organism=Drosophila melanogaster, GI24583427, Length=254, Percent_Identity=37.7952755905512, Blast_Score=179, Evalue=2e-45,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 31700; Mature: 31700

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METQVNQDLKGRQTKDGIRIYDAADFAGMRKAGALTARILDDIADLVFVGQTTGAIDKRI
CCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHH
EEMVEEAGATSATINYKGYKHASCISVNSVVCHGIPGAPIPKSGSETISKDPEKRRDDDV
HHHHHHCCCCEEEEECCCCCCCCEEEECCEEEECCCCCCCCCCCCCHHHCCCHHCCCCCH
LRDGDILNIDVTAIVDGWFGDSSRMYVAGTAPKKAQKLIQVTHDALMRGIEAVKPGNTFG
HCCCCEEEEEEEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHH
DIGYAIQSFVESNRMSVVRDFCGHGLGRVFHAPPNVLHYGRPGTGAVLEEGMFFTIEPMV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCEECCCCCCCHHHHCCCEEEEECHH
NLGRPETKTLADDWTAVTRDKTLSAQFEHSIGVTADGAEIFTLSPAGRFHPTSG
CCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCEECCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
METQVNQDLKGRQTKDGIRIYDAADFAGMRKAGALTARILDDIADLVFVGQTTGAIDKRI
CCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHH
EEMVEEAGATSATINYKGYKHASCISVNSVVCHGIPGAPIPKSGSETISKDPEKRRDDDV
HHHHHHCCCCEEEEECCCCCCCCEEEECCEEEECCCCCCCCCCCCCHHHCCCHHCCCCCH
LRDGDILNIDVTAIVDGWFGDSSRMYVAGTAPKKAQKLIQVTHDALMRGIEAVKPGNTFG
HCCCCEEEEEEEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHH
DIGYAIQSFVESNRMSVVRDFCGHGLGRVFHAPPNVLHYGRPGTGAVLEEGMFFTIEPMV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCEECCCCCCCHHHHCCCEEEEECHH
NLGRPETKTLADDWTAVTRDKTLSAQFEHSIGVTADGAEIFTLSPAGRFHPTSG
CCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCEECCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]