Click here to switch to the map view.

The map label for this gene is yleA [C]

Identifier: 110678170

GI number: 110678170

Start: 796622

End: 797875

Strand: Direct

Name: yleA [C]

Synonym: RD1_0814

Alternate gene names: 110678170

Gene position: 796622-797875 (Clockwise)

Preceding gene: 110678169

Following gene: 110678171

Centisome position: 19.27

GC content: 59.01

Gene sequence:

>1254_bases
ATGAGCGCACCCAAATTCACGACCCTTGGCTGCCGTTTGAACGCCTATGAGACCGAAGCAATGAAAGAACTCGCCGCTGA
GGCCGGTCTGTCGGATGCTGTGGTGGTAAACACCTGTGCGGTGACGGGCGAAGCCGTGCGCAAAGCCCGCAGTACGATCC
GTAAACTGCGGCGTGAAAACCCGACAGCACGCCTGATCGTTACCGGATGCGCCGCCCAGACAGAGCCGCAAACCTTTGCC
GCGATGCCCGAAGTTAATGCGGTCATTGGTAACACCGAAAAGATGCAGGGCGATACCTGGGGCGCGCTCGCCGCCGATTT
CATCGGCGAAAGCGAAGCGGTGCAAGTTGATGACATCATGTCCGTGACCGAGACCGCAGGTCATCTGATTGACGGCTTTG
GCACCCGGAGCCGGGCTTATGTGCAGGTGCAGAACGGGTGCGACCATCGCTGTACTTTTTGCATCATCCCCTATGGCCGC
GGCAATTCGCGGTCGGTTCCGGCTGGCGTTGTTGTCGACCAGATCAAGCGTTTGGTCGATAAGGGGTTCAACGAGGTCGT
GCTCACGGGCGTGGACCTGACCAGTTGGGGGGCGGATTTACCGGCCCAGCCAAAGCTTGGTGATCTGGTCATGCGAATTC
TCAGGCTTGTCCCGGATTTGCCGCGTTTGCGGATTAGTTCAATCGACAGCATCGAGGTTGACGAAAACCTGATGCAGGCG
ATTGCCACCGAGCATCGGTTGATGCCGCATTTGCACCTGTCATTGCAGCACGGCGATGACATGATCCTCAAGCGGATGAA
AAGGCGGCACTTGCGGGATGACGCCATTCGCTTTGCGCAGGATGCCCGGCGTTTGCGGCCGGATATGACGTTTGGCGCTG
ATATCATCGTGGGTTTTCCGACCGAAACGGAGGCGATGTTCGATAACTCCCTGGCGCTGGTTGAGGAGTGCGATCTGACG
TGGCTGCATGTTTTTCCCTACTCCGCGCGACCAGGCACACCTGCGGCGCGCATGCCTGCTGTCCATGGTCAGATCATCAA
GGAACGGGCATCGCGCTTGCGCGCCGCCGGAGACGCGCAAGTCCAGCGACATCTTTCCGCGCAGGTTGGTAAGGTGCACA
ACGTGCTGATGGAAAGTGCGTCCAGGGGGCGTACCGAGCAGTTTACCGAAGTTCAGGTTTCGACACCGCGACAAGAAGGC
AGGATCATCCCGTTGCCCATCACAGGGACCGTTGGTGCCGCTTTGCAGGGGTGA

Upstream 100 bases:

>100_bases
GGTTGGAGATTGACTGGCGCGAGGATGGTGTTTGGATGACCGGCCCGACGCAGCATGTGTTTTCCGGAACGCTCACGCGG
TCCTTTCTGGAGAGCATCGC

Downstream 100 bases:

>100_bases
AGGGGTTCTTTTGCAGGCCCTGTCGCACGTATCTTTTCAATGCCGTAAGGTCGCCCGTCAGAGATGCAGGCCCGAATGGT
CATCGCGGTCTGTGGGGCCG

Product: MiaB-like tRNA modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSAPKFTTLGCRLNAYETEAMKELAAEAGLSDAVVVNTCAVTGEAVRKARSTIRKLRRENPTARLIVTGCAAQTEPQTFA
AMPEVNAVIGNTEKMQGDTWGALAADFIGESEAVQVDDIMSVTETAGHLIDGFGTRSRAYVQVQNGCDHRCTFCIIPYGR
GNSRSVPAGVVVDQIKRLVDKGFNEVVLTGVDLTSWGADLPAQPKLGDLVMRILRLVPDLPRLRISSIDSIEVDENLMQA
IATEHRLMPHLHLSLQHGDDMILKRMKRRHLRDDAIRFAQDARRLRPDMTFGADIIVGFPTETEAMFDNSLALVEECDLT
WLHVFPYSARPGTPAARMPAVHGQIIKERASRLRAAGDAQVQRHLSAQVGKVHNVLMESASRGRTEQFTEVQVSTPRQEG
RIIPLPITGTVGAALQG

Sequences:

>Translated_417_residues
MSAPKFTTLGCRLNAYETEAMKELAAEAGLSDAVVVNTCAVTGEAVRKARSTIRKLRRENPTARLIVTGCAAQTEPQTFA
AMPEVNAVIGNTEKMQGDTWGALAADFIGESEAVQVDDIMSVTETAGHLIDGFGTRSRAYVQVQNGCDHRCTFCIIPYGR
GNSRSVPAGVVVDQIKRLVDKGFNEVVLTGVDLTSWGADLPAQPKLGDLVMRILRLVPDLPRLRISSIDSIEVDENLMQA
IATEHRLMPHLHLSLQHGDDMILKRMKRRHLRDDAIRFAQDARRLRPDMTFGADIIVGFPTETEAMFDNSLALVEECDLT
WLHVFPYSARPGTPAARMPAVHGQIIKERASRLRAAGDAQVQRHLSAQVGKVHNVLMESASRGRTEQFTEVQVSTPRQEG
RIIPLPITGTVGAALQG
>Mature_416_residues
SAPKFTTLGCRLNAYETEAMKELAAEAGLSDAVVVNTCAVTGEAVRKARSTIRKLRRENPTARLIVTGCAAQTEPQTFAA
MPEVNAVIGNTEKMQGDTWGALAADFIGESEAVQVDDIMSVTETAGHLIDGFGTRSRAYVQVQNGCDHRCTFCIIPYGRG
NSRSVPAGVVVDQIKRLVDKGFNEVVLTGVDLTSWGADLPAQPKLGDLVMRILRLVPDLPRLRISSIDSIEVDENLMQAI
ATEHRLMPHLHLSLQHGDDMILKRMKRRHLRDDAIRFAQDARRLRPDMTFGADIIVGFPTETEAMFDNSLALVEECDLTW
LHVFPYSARPGTPAARMPAVHGQIIKERASRLRAAGDAQVQRHLSAQVGKVHNVLMESASRGRTEQFTEVQVSTPRQEGR
IIPLPITGTVGAALQG

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=366, Percent_Identity=27.3224043715847, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI28872782, Length=374, Percent_Identity=22.9946524064171, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI28872784, Length=374, Percent_Identity=22.9946524064171, Blast_Score=109, Evalue=5e-24,
Organism=Escherichia coli, GI1786882, Length=449, Percent_Identity=26.9487750556793, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1787057, Length=379, Percent_Identity=28.7598944591029, Blast_Score=139, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17553146, Length=369, Percent_Identity=27.9132791327913, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71996771, Length=240, Percent_Identity=27.5, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21356207, Length=423, Percent_Identity=26.0047281323877, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI19922432, Length=410, Percent_Identity=24.8780487804878, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 45635; Mature: 45504

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPKFTTLGCRLNAYETEAMKELAAEAGLSDAVVVNTCAVTGEAVRKARSTIRKLRREN
CCCCCEEEECEEECCHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCC
PTARLIVTGCAAQTEPQTFAAMPEVNAVIGNTEKMQGDTWGALAADFIGESEAVQVDDIM
CCEEEEEEECCCCCCCCHHHCCCCCHHHHCCCHHCCCCCHHHHHHHHCCCCCCEEHHHHH
SVTETAGHLIDGFGTRSRAYVQVQNGCDHRCTFCIIPYGRGNSRSVPAGVVVDQIKRLVD
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
KGFNEVVLTGVDLTSWGADLPAQPKLGDLVMRILRLVPDLPRLRISSIDSIEVDENLMQA
CCCCEEEEEECCHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
IATEHRLMPHLHLSLQHGDDMILKRMKRRHLRDDAIRFAQDARRLRPDMTFGADIIVGFP
HHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECC
TETEAMFDNSLALVEECDLTWLHVFPYSARPGTPAARMPAVHGQIIKERASRLRAAGDAQ
CCHHHHHCCCHHHHHHCCEEEEEEEECCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCHHH
VQRHLSAQVGKVHNVLMESASRGRTEQFTEVQVSTPRQEGRIIPLPITGTVGAALQG
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SAPKFTTLGCRLNAYETEAMKELAAEAGLSDAVVVNTCAVTGEAVRKARSTIRKLRREN
CCCCEEEECEEECCHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCC
PTARLIVTGCAAQTEPQTFAAMPEVNAVIGNTEKMQGDTWGALAADFIGESEAVQVDDIM
CCEEEEEEECCCCCCCCHHHCCCCCHHHHCCCHHCCCCCHHHHHHHHCCCCCCEEHHHHH
SVTETAGHLIDGFGTRSRAYVQVQNGCDHRCTFCIIPYGRGNSRSVPAGVVVDQIKRLVD
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
KGFNEVVLTGVDLTSWGADLPAQPKLGDLVMRILRLVPDLPRLRISSIDSIEVDENLMQA
CCCCEEEEEECCHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
IATEHRLMPHLHLSLQHGDDMILKRMKRRHLRDDAIRFAQDARRLRPDMTFGADIIVGFP
HHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECC
TETEAMFDNSLALVEECDLTWLHVFPYSARPGTPAARMPAVHGQIIKERASRLRAAGDAQ
CCHHHHHCCCHHHHHHCCEEEEEEEECCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCHHH
VQRHLSAQVGKVHNVLMESASRGRTEQFTEVQVSTPRQEGRIIPLPITGTVGAALQG
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]