Click here to switch to the map view.

The map label for this gene is ydiD [C]

Identifier: 110678077

GI number: 110678077

Start: 679654

End: 681624

Strand: Direct

Name: ydiD [C]

Synonym: RD1_0702

Alternate gene names: 110678077

Gene position: 679654-681624 (Clockwise)

Preceding gene: 110678076

Following gene: 110678078

Centisome position: 16.44

GC content: 57.28

Gene sequence:

>1971_bases
TTGAATACTGTTCCAACGCAGGTCGACGGACCACAGTCCGTCCCGGCGCTGCTGCATCGTAATGCCAAAGAGTTCGCGGA
CGCACCTGCGTATCGCGAGAAAGAGTACGGGATCTGGCAGTCGTGGACATGGGCCGAGACCTTGGAAGAGGTCGAAGCGC
TGGCCCTTGGGCTTGTTGACTTGGGTGTGCAGGAAGGTGACTTCATTGCAGTCATCGGGCGCAATCGGCCCCGGCTTTAC
TGGGCAATGATCGCTGCAGAGATGGTCGGCGCGGTGCCGGTTCCGCTCTATCAGGATGCGGTGGCCGAAGAGATGGCCTA
TGTCCTGAGCCACTGTGGTGCGCGTTTCGTGATCGTGGGCGATCAGGAGCAGGTCGATAAGGTCATCGAAATCGGTGACC
AACTGCCCAGTTTCGAGCAGATGATCTATCTCGACCCGCGCGGTCTGCGCAAATACGATCATTCGAAACTGCACCAGTAT
ACACATGTGCAGGATGCAGGCCGCGCCAAGCGGGACGAACTGCTGCCCGAAATCACGGCCCGGCAGGCCAAGCTGAATTA
CGACAGCACCTGCGTCATGCTCTATACGTCCGGCACTACGGGCAAGCCAAAAGGGGTGGTGCTGAGCAACCGCAATGTGA
TTGAGACTTCCAAATCATCCTCGGAATTTGATGATCTGCGGCAAACGGATTCGATCCTTGCCTATTTGCCGATGGCATGG
GTCGGGGATTTCATTTTTTCCGTCGGTCAGGCGCTGTGGACAGGGTTTTGCACCAACTGCCCGGAAAGTGCCGAGACAAT
GCACACCGACCTGCGTGAGATTGGTCCGACCTATTACTTTGCACCGCCGCGCGTTTTCGAGACGCAGTTGACCAATGTGA
TGATCCGTATGGAAGACGCAGGCCGGTTCAAAAAATGGCTGTTTGACTATTTCATGGCCCATGCGCGCCGCGTCGGGCCG
GATATTCTGGATGGTCAACCGGTGAACCAATGGGACCGCTTCAAATACAACATTGGCGAATTGGCGATTTACGGGCCCCT
CAAGAATACATTGGGGTTCAGCCGGATTCGGGTGGGGTACACGGCTGGCGAAGCGATCGGGCCCGAGATTTTCGACTTTT
TTCGCTCACTCGGGATCAACCTCAAGCAGCTTTACGGGCAGACCGAAGCGACCGTGTTCATCACCGCGCAACCCGATGGC
GAGGTGCGATCCGACACGGTTGGTGTGACCTGCCCCGGTGTTGAATTGAAGATCGCGGAGAATGGCGAAGTCTTTTACCG
CAGTCCGGGCGTGTTTGTCGAATATTTCAAAAACCCCGAAAGCACGGCAGACACCAAGGACGCCGAGGGTTGGGTGGCCA
CGGGGGATGCGGGCTTTATCGAAGAGGACACGGGCCACCTGAGGATCATCGACCGCGCCAAGGATGTCGGGAAAATGGCC
GACGGATCCCTCTTTGCGCCGAAATACGCCGAGAATAAGCTCAAGTTTTTCCCGAATATTCTGGAAGCGGTCGTGTTTGG
CAACGGGCGCGACGAATGCACGGCCTTTATCAACATCGACCTGACTGCCGTAGGTAACTGGGCGGAGCGGAACAACATTG
GCTACGCGTCCTATCAGGAACTGGCGCGTCACCCGCAGGTGATGGGCATGATTCAGGAACACGTCGAAGAAGTGAACGCA
TCCGTCGCCGAGGATGTGATGCTGTCGGGCTGTCAGGTTCATCGTTTTGTGGTGCTGCACAAGGAACTGGACGCGGATGA
TGGCGAGCTGACCCGCACCCGCAAGGTGCGCCGTCGGATCATCGAAGAGAAATACGCCGATATCATTGCAGCACTCTATG
ATGGGTCGCCCGAGGTCTCGACTGTGACCGAAGTGACCTATGAAGACGGGCGCAAGGGCTCAATCTCCGCAACGCTGGAA
GTTCGGGTGGCAGCGGTGCACCCGGTTGGCGCAAGGATGGCAGCGCAATGA

Upstream 100 bases:

>100_bases
AAAAAGTTGACCTTCATCTGAAAACTTACATTGTTGTGCACACGACGGTCAAAAAACGACCGCACTTGCCTTTCAATGGC
AAGGTCTGGGAGGACGAAAA

Downstream 100 bases:

>100_bases
TGCACGCGGCGTGCCCCCTCGTTTATCAGAGGTATGAATGAAAGATACTATTGACGGCTACGTGACCGAAGATGGCCGCC
GGATCGGTCCGGTGGTGATG

Product: putative AMP-binding enzyme

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase; LACS [H]

Number of amino acids: Translated: 656; Mature: 656

Protein sequence:

>656_residues
MNTVPTQVDGPQSVPALLHRNAKEFADAPAYREKEYGIWQSWTWAETLEEVEALALGLVDLGVQEGDFIAVIGRNRPRLY
WAMIAAEMVGAVPVPLYQDAVAEEMAYVLSHCGARFVIVGDQEQVDKVIEIGDQLPSFEQMIYLDPRGLRKYDHSKLHQY
THVQDAGRAKRDELLPEITARQAKLNYDSTCVMLYTSGTTGKPKGVVLSNRNVIETSKSSSEFDDLRQTDSILAYLPMAW
VGDFIFSVGQALWTGFCTNCPESAETMHTDLREIGPTYYFAPPRVFETQLTNVMIRMEDAGRFKKWLFDYFMAHARRVGP
DILDGQPVNQWDRFKYNIGELAIYGPLKNTLGFSRIRVGYTAGEAIGPEIFDFFRSLGINLKQLYGQTEATVFITAQPDG
EVRSDTVGVTCPGVELKIAENGEVFYRSPGVFVEYFKNPESTADTKDAEGWVATGDAGFIEEDTGHLRIIDRAKDVGKMA
DGSLFAPKYAENKLKFFPNILEAVVFGNGRDECTAFINIDLTAVGNWAERNNIGYASYQELARHPQVMGMIQEHVEEVNA
SVAEDVMLSGCQVHRFVVLHKELDADDGELTRTRKVRRRIIEEKYADIIAALYDGSPEVSTVTEVTYEDGRKGSISATLE
VRVAAVHPVGARMAAQ

Sequences:

>Translated_656_residues
MNTVPTQVDGPQSVPALLHRNAKEFADAPAYREKEYGIWQSWTWAETLEEVEALALGLVDLGVQEGDFIAVIGRNRPRLY
WAMIAAEMVGAVPVPLYQDAVAEEMAYVLSHCGARFVIVGDQEQVDKVIEIGDQLPSFEQMIYLDPRGLRKYDHSKLHQY
THVQDAGRAKRDELLPEITARQAKLNYDSTCVMLYTSGTTGKPKGVVLSNRNVIETSKSSSEFDDLRQTDSILAYLPMAW
VGDFIFSVGQALWTGFCTNCPESAETMHTDLREIGPTYYFAPPRVFETQLTNVMIRMEDAGRFKKWLFDYFMAHARRVGP
DILDGQPVNQWDRFKYNIGELAIYGPLKNTLGFSRIRVGYTAGEAIGPEIFDFFRSLGINLKQLYGQTEATVFITAQPDG
EVRSDTVGVTCPGVELKIAENGEVFYRSPGVFVEYFKNPESTADTKDAEGWVATGDAGFIEEDTGHLRIIDRAKDVGKMA
DGSLFAPKYAENKLKFFPNILEAVVFGNGRDECTAFINIDLTAVGNWAERNNIGYASYQELARHPQVMGMIQEHVEEVNA
SVAEDVMLSGCQVHRFVVLHKELDADDGELTRTRKVRRRIIEEKYADIIAALYDGSPEVSTVTEVTYEDGRKGSISATLE
VRVAAVHPVGARMAAQ
>Mature_656_residues
MNTVPTQVDGPQSVPALLHRNAKEFADAPAYREKEYGIWQSWTWAETLEEVEALALGLVDLGVQEGDFIAVIGRNRPRLY
WAMIAAEMVGAVPVPLYQDAVAEEMAYVLSHCGARFVIVGDQEQVDKVIEIGDQLPSFEQMIYLDPRGLRKYDHSKLHQY
THVQDAGRAKRDELLPEITARQAKLNYDSTCVMLYTSGTTGKPKGVVLSNRNVIETSKSSSEFDDLRQTDSILAYLPMAW
VGDFIFSVGQALWTGFCTNCPESAETMHTDLREIGPTYYFAPPRVFETQLTNVMIRMEDAGRFKKWLFDYFMAHARRVGP
DILDGQPVNQWDRFKYNIGELAIYGPLKNTLGFSRIRVGYTAGEAIGPEIFDFFRSLGINLKQLYGQTEATVFITAQPDG
EVRSDTVGVTCPGVELKIAENGEVFYRSPGVFVEYFKNPESTADTKDAEGWVATGDAGFIEEDTGHLRIIDRAKDVGKMA
DGSLFAPKYAENKLKFFPNILEAVVFGNGRDECTAFINIDLTAVGNWAERNNIGYASYQELARHPQVMGMIQEHVEEVNA
SVAEDVMLSGCQVHRFVVLHKELDADDGELTRTRKVRRRIIEEKYADIIAALYDGSPEVSTVTEVTYEDGRKGSISATLE
VRVAAVHPVGARMAAQ

Specific function: Unknown

COG id: COG1022

COG function: function code I; Long-chain acyl-CoA synthetases (AMP-forming)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI27477105, Length=639, Percent_Identity=23.6306729264476, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI40807491, Length=607, Percent_Identity=24.8764415156507, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI83745141, Length=631, Percent_Identity=21.3946117274168, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI57165412, Length=606, Percent_Identity=24.2574257425743, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI42794756, Length=614, Percent_Identity=23.7785016286645, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI42794760, Length=614, Percent_Identity=23.7785016286645, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI42794758, Length=614, Percent_Identity=23.7785016286645, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI57165410, Length=611, Percent_Identity=24.2225859247136, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI12669909, Length=618, Percent_Identity=22.6537216828479, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI4758332, Length=618, Percent_Identity=22.6537216828479, Blast_Score=107, Evalue=4e-23,
Organism=Escherichia coli, GI145693145, Length=484, Percent_Identity=23.1404958677686, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI221142682, Length=208, Percent_Identity=25.9615384615385, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17556552, Length=620, Percent_Identity=23.3870967741935, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17564090, Length=635, Percent_Identity=24.7244094488189, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17510401, Length=605, Percent_Identity=23.9669421487603, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17541856, Length=608, Percent_Identity=24.3421052631579, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17553312, Length=612, Percent_Identity=23.3660130718954, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25147511, Length=630, Percent_Identity=22.5396825396825, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI193204819, Length=665, Percent_Identity=23.4586466165414, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17558820, Length=160, Percent_Identity=31.875, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI32563687, Length=161, Percent_Identity=32.9192546583851, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI133901848, Length=209, Percent_Identity=22.9665071770335, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71985884, Length=139, Percent_Identity=30.9352517985612, Blast_Score=69, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6320852, Length=613, Percent_Identity=22.5122349102773, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323903, Length=501, Percent_Identity=25.1497005988024, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324893, Length=337, Percent_Identity=27.5964391691395, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI19921316, Length=661, Percent_Identity=26.6263237518911, Blast_Score=202, Evalue=5e-52,
Organism=Drosophila melanogaster, GI17933690, Length=639, Percent_Identity=25.0391236306729, Blast_Score=191, Evalue=2e-48,
Organism=Drosophila melanogaster, GI281366413, Length=526, Percent_Identity=26.0456273764259, Blast_Score=144, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24666501, Length=526, Percent_Identity=26.0456273764259, Blast_Score=143, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24666497, Length=526, Percent_Identity=26.0456273764259, Blast_Score=143, Evalue=5e-34,
Organism=Drosophila melanogaster, GI62471679, Length=617, Percent_Identity=22.0421393841167, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI62471683, Length=617, Percent_Identity=22.0421393841167, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI62471685, Length=617, Percent_Identity=22.0421393841167, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24586636, Length=617, Percent_Identity=22.0421393841167, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI62471689, Length=617, Percent_Identity=22.0421393841167, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI62471681, Length=617, Percent_Identity=22.0421393841167, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI62471687, Length=617, Percent_Identity=22.0421393841167, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24586634, Length=617, Percent_Identity=22.0421393841167, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI22026970, Length=617, Percent_Identity=22.0421393841167, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281365686, Length=137, Percent_Identity=31.3868613138686, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21358303, Length=479, Percent_Identity=22.1294363256785, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648257, Length=150, Percent_Identity=29.3333333333333, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 73267; Mature: 73267

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVPTQVDGPQSVPALLHRNAKEFADAPAYREKEYGIWQSWTWAETLEEVEALALGLVD
CCCCCCCCCCCCHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LGVQEGDFIAVIGRNRPRLYWAMIAAEMVGAVPVPLYQDAVAEEMAYVLSHCGARFVIVG
CCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEC
DQEQVDKVIEIGDQLPSFEQMIYLDPRGLRKYDHSKLHQYTHVQDAGRAKRDELLPEITA
CHHHHHHHHHHHHCCCCCHHEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RQAKLNYDSTCVMLYTSGTTGKPKGVVLSNRNVIETSKSSSEFDDLRQTDSILAYLPMAW
HHHCCCCCCEEEEEEECCCCCCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHH
VGDFIFSVGQALWTGFCTNCPESAETMHTDLREIGPTYYFAPPRVFETQLTNVMIRMEDA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHEEEEEECCC
GRFKKWLFDYFMAHARRVGPDILDGQPVNQWDRFKYNIGELAIYGPLKNTLGFSRIRVGY
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCEECCCCEEEECCHHHHCCCHHEEEEE
TAGEAIGPEIFDFFRSLGINLKQLYGQTEATVFITAQPDGEVRSDTVGVTCPGVELKIAE
CCCCCCCHHHHHHHHHHCCCHHHHCCCCCEEEEEEECCCCCCCCCEEEEECCCEEEEEEC
NGEVFYRSPGVFVEYFKNPESTADTKDAEGWVATGDAGFIEEDTGHLRIIDRAKDVGKMA
CCCEEEECCCCEEEEECCCCCCCCCCCCCCEEEECCCCCEECCCCCEEEEECHHHHCCCC
DGSLFAPKYAENKLKFFPNILEAVVFGNGRDECTAFINIDLTAVGNWAERNNIGYASYQE
CCCEECCHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEECCCHHHCCCCCHHHHH
LARHPQVMGMIQEHVEEVNASVAEDVMLSGCQVHRFVVLHKELDADDGELTRTRKVRRRI
HHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHCCCCCCHHHHHHHHHHHH
IEEKYADIIAALYDGSPEVSTVTEVTYEDGRKGSISATLEVRVAAVHPVGARMAAQ
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEEEEEEECCCCCHHCCC
>Mature Secondary Structure
MNTVPTQVDGPQSVPALLHRNAKEFADAPAYREKEYGIWQSWTWAETLEEVEALALGLVD
CCCCCCCCCCCCHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LGVQEGDFIAVIGRNRPRLYWAMIAAEMVGAVPVPLYQDAVAEEMAYVLSHCGARFVIVG
CCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEC
DQEQVDKVIEIGDQLPSFEQMIYLDPRGLRKYDHSKLHQYTHVQDAGRAKRDELLPEITA
CHHHHHHHHHHHHCCCCCHHEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RQAKLNYDSTCVMLYTSGTTGKPKGVVLSNRNVIETSKSSSEFDDLRQTDSILAYLPMAW
HHHCCCCCCEEEEEEECCCCCCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHH
VGDFIFSVGQALWTGFCTNCPESAETMHTDLREIGPTYYFAPPRVFETQLTNVMIRMEDA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHEEEEEECCC
GRFKKWLFDYFMAHARRVGPDILDGQPVNQWDRFKYNIGELAIYGPLKNTLGFSRIRVGY
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCEECCCCEEEECCHHHHCCCHHEEEEE
TAGEAIGPEIFDFFRSLGINLKQLYGQTEATVFITAQPDGEVRSDTVGVTCPGVELKIAE
CCCCCCCHHHHHHHHHHCCCHHHHCCCCCEEEEEEECCCCCCCCCEEEEECCCEEEEEEC
NGEVFYRSPGVFVEYFKNPESTADTKDAEGWVATGDAGFIEEDTGHLRIIDRAKDVGKMA
CCCEEEECCCCEEEEECCCCCCCCCCCCCCEEEECCCCCEECCCCCEEEEECHHHHCCCC
DGSLFAPKYAENKLKFFPNILEAVVFGNGRDECTAFINIDLTAVGNWAERNNIGYASYQE
CCCEECCHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEECCCHHHCCCCCHHHHH
LARHPQVMGMIQEHVEEVNASVAEDVMLSGCQVHRFVVLHKELDADDGELTRTRKVRRRI
HHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHCCCCCCHHHHHHHHHHHH
IEEKYADIIAALYDGSPEVSTVTEVTYEDGRKGSISATLEVRVAAVHPVGARMAAQ
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEEEEEEECCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]