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The map label for this gene is idi

Identifier: 110677560

GI number: 110677560

Start: 147827

End: 148357

Strand: Direct

Name: idi

Synonym: RD1_0147

Alternate gene names: 110677560

Gene position: 147827-148357 (Clockwise)

Preceding gene: 110677559

Following gene: 110677561

Centisome position: 3.58

GC content: 57.82

Gene sequence:

>531_bases
ATGACGATCATGATCCCGGCCTGGGTAAATGGCACGCTGACATCCGTTGAAAAGCTAGAGGCCCATGTAAAAGGGCTGCG
CCACAAAGCCGTGTCGGTTTTTGTGCTCAAGGGGGACGCGGTGTTGATGCAACAACGCGCCATGTGCAAATACCATACGC
CGGGGCTGTGGACGAACACATGTTGCACGCATCCCGAATGGGATGAGGCCCCCGAGGTTTGCGCGATCCGCCGTCTGGAT
GAAGAGCTTGGGGTGCGCGGCTTGATCCCTCAACACCGCCATCACCTCGAATACCGCGCGGATGTGGGCGGCGGCTTGAT
TGAGCATGAAGTGGTCGACGTCTTTGTCGCGGAGGCGGATGAAACCCTCGTCGTGTTGCCGAATCCGGATGAGGTCATGG
CAGTCGAATGGGTGCACTTTGATGATCTGGTCGATCAGGTCGCGCAACACCCCGACAGATATACGCCATGGCTTCGCATC
TACCTGAGGGATCACGCGGCCACGATTTTCGGGGAACTTGCCCTGCTTTAA

Upstream 100 bases:

>100_bases
ATATGAACAAGAAGCTCGTGCGCGCCCGGCCCATGGCCCACCTCAAGATCGGGATAAAAAACCTTGCGCATCTGACAGGC
CTTGTGGCAACGACGCGCGT

Downstream 100 bases:

>100_bases
AGCGTCTGACGAAATACCTCAAACATCAAGCATCATGTAACGCGTTGAAATCTTTGGTTTCTGGCAGCGTAACGTGATCG
AGGTTTTTCACATGACGCTT

Product: isopentyl-diphosphate delta-isomerase

Products: NA

Alternate protein names: IPP isomerase; IPP:DMAPP isomerase; Isopentenyl pyrophosphate isomerase

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MTIMIPAWVNGTLTSVEKLEAHVKGLRHKAVSVFVLKGDAVLMQQRAMCKYHTPGLWTNTCCTHPEWDEAPEVCAIRRLD
EELGVRGLIPQHRHHLEYRADVGGGLIEHEVVDVFVAEADETLVVLPNPDEVMAVEWVHFDDLVDQVAQHPDRYTPWLRI
YLRDHAATIFGELALL

Sequences:

>Translated_176_residues
MTIMIPAWVNGTLTSVEKLEAHVKGLRHKAVSVFVLKGDAVLMQQRAMCKYHTPGLWTNTCCTHPEWDEAPEVCAIRRLD
EELGVRGLIPQHRHHLEYRADVGGGLIEHEVVDVFVAEADETLVVLPNPDEVMAVEWVHFDDLVDQVAQHPDRYTPWLRI
YLRDHAATIFGELALL
>Mature_175_residues
TIMIPAWVNGTLTSVEKLEAHVKGLRHKAVSVFVLKGDAVLMQQRAMCKYHTPGLWTNTCCTHPEWDEAPEVCAIRRLDE
ELGVRGLIPQHRHHLEYRADVGGGLIEHEVVDVFVAEADETLVVLPNPDEVMAVEWVHFDDLVDQVAQHPDRYTPWLRIY
LRDHAATIFGELALL

Specific function: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)

COG id: COG1443

COG function: function code I; Isopentenyldiphosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Homo sapiens, GI40018633, Length=155, Percent_Identity=32.9032258064516, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1789255, Length=147, Percent_Identity=34.6938775510204, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17554092, Length=163, Percent_Identity=34.3558282208589, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6325140, Length=179, Percent_Identity=32.9608938547486, Blast_Score=83, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281362205, Length=152, Percent_Identity=32.8947368421053, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24648688, Length=152, Percent_Identity=32.8947368421053, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IDI_ROSDO (Q16DR2)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_680567.1
- ProteinModelPortal:   Q16DR2
- SMR:   Q16DR2
- STRING:   Q16DR2
- GeneID:   4198199
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_0147
- NMPDR:   fig|375451.6.peg.140
- eggNOG:   COG1443
- HOGENOM:   HBG416977
- OMA:   HKAVSVF
- PhylomeDB:   Q16DR2
- ProtClustDB:   CLSK933164
- BioCyc:   RDEN375451:RD1_0147-MONOMER
- GO:   GO:0005737
- GO:   GO:0015979
- HAMAP:   MF_00202
- InterPro:   IPR011876
- InterPro:   IPR000086
- InterPro:   IPR015797
- Gene3D:   G3DSA:3.90.79.10
- PANTHER:   PTHR10885
- PIRSF:   PIRSF018427
- TIGRFAMs:   TIGR02150

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: =5.3.3.2

Molecular weight: Translated: 19991; Mature: 19860

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS51462 NUDIX

Important sites: ACT_SITE 62-62 ACT_SITE 110-110

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIMIPAWVNGTLTSVEKLEAHVKGLRHKAVSVFVLKGDAVLMQQRAMCKYHTPGLWTNT
CEEEEEECCCCHHHHHHHHHHHHHHHHHCEEEEEEEECCHHHHHHHHHHEECCCCCCCCC
CCTHPEWDEAPEVCAIRRLDEELGVRGLIPQHRHHLEYRADVGGGLIEHEVVDVFVAEAD
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCEEECCCCCCHHHHHHHHHEEECCC
ETLVVLPNPDEVMAVEWVHFDDLVDQVAQHPDRYTPWLRIYLRDHAATIFGELALL
CEEEEECCCCCEEEEEEECHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHCC
>Mature Secondary Structure 
TIMIPAWVNGTLTSVEKLEAHVKGLRHKAVSVFVLKGDAVLMQQRAMCKYHTPGLWTNT
EEEEEECCCCHHHHHHHHHHHHHHHHHCEEEEEEEECCHHHHHHHHHHEECCCCCCCCC
CCTHPEWDEAPEVCAIRRLDEELGVRGLIPQHRHHLEYRADVGGGLIEHEVVDVFVAEAD
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCEEECCCCCCHHHHHHHHHEEECCC
ETLVVLPNPDEVMAVEWVHFDDLVDQVAQHPDRYTPWLRIYLRDHAATIFGELALL
CEEEEECCCCCEEEEEEECHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA