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The map label for this gene is opuAB [H]

Identifier: 110677434

GI number: 110677434

Start: 14913

End: 16892

Strand: Direct

Name: opuAB [H]

Synonym: RD1_0015

Alternate gene names: 110677434

Gene position: 14913-16892 (Clockwise)

Preceding gene: 110677433

Following gene: 110677442

Centisome position: 0.36

GC content: 59.65

Gene sequence:

>1980_bases
ATGGCGATTGTTGCAACAAACACCGAAAGCCAGACAACGCCACTGTCATCGCGCACTTTGGGGTTGGGGCTCTTTCTTTT
CGCCGTCGCACTGACCTTGCTGCACTACGCGGGTCTCTTGCCAGCGTGGCTGCACCGGCTGCCCGAAGCGGTGATCCCGC
CCTTTGAGACATGGCTTGATGCGATTTTCAACTTTGTCAAAGACGACCTTGGCCTGCTCGCCCTGACGCGGTTTCTGACC
GGAGGGCTTGAAGCGGTGCTCGATGTGACCGCGAACCTGCTTTATGGCAAACGTCGCTGGCCCTTCATCGACCCCATTCC
ATGGAGCGCGATCGCAGCGGCAACGACCGTGCTTGGCTATTATCTTGGTGGCTGGCGGCTGGCGGCTCTGGCGGGGGGCA
CCTGTGTCTGGACCGCGATGATCGGCCAGTGGGAAATCGCCATGGAAACCATGTCGGTGCTGGTTATCTCAGCGCCCCTT
GCTTTTATGATCGGTCTGCTGGTCGGTATCTATGCGTGGAAATCCCCGTCGTTCAATCGCGCGCTGCTGCCGTTCCTGTC
GGTCATGCAGACTCTGCCGTTTTTCACCTACCTGCTTCCGGCGGTGATCTTCTTCAAGGTCGGCCCGACGGCGGCGGCGG
TGGCCACGACGGTTTTCGCCATCCCCCCGATGATCCTGATGACGACGCTCGGCCTGCAAAAGGTATCCTCCGAAGTTGTC
GAGGCGGGCAAGATGAGTGGTTGCACGCGCTTTCAGATGATGCGGCATGTCTACCTTCCGTCGGCCCGCACCGAGATCCT
CGTCGGCGTGAACCAGGTCATCATGCTCTGTCTGGCAATGGTCGTTCTGACAGCCTTTATCGGGATGCCGGGACTTGGCG
CAAAACTCTTGCAGATGCTCGGCAGCTTCAAGATCGGCCGCGCATTCGAGATCGGCGTCACCATCGTGCTGGTCGCGATC
ACACTTGATCGCCTGTCCAAAGCATGGGTTGCGAAACTGCCCGAACACTTTGATCGTGGCACACCTTTCTACATCCGGCA
CAAATATCTGGTTGCCGGTGCCGTGGGCTTTGCGCTGTTCTTCGCACTCGCGCAGCTGGTTCCCATCCTTGCAGAAGTCG
GGCGGCGGCAATCGCTGTCACAGGGCCGCGAGATTGACCAGTTGATCAAAGCCTACCTTGCGCTGGATTGGGTGAAAGCA
TCGACCGACGCCATGCGCTACGTGCTGAACGTCTGGATCCTCAACCCGTTCCGCGACTTCCTGCTCAGCATCCCGACAAG
TGCGTTCATCATTCTGGTGGTTGCCGCCGGGCTGGTGATCGCCGGGCCGCGTCAGGCGGTTCTGGCGGCAGTCTTCTTCA
GCCTTGTCGCGCTCAGCGGCTGGTGGGACAGATCAGTGATCACGCTCTATTCCGTGATTGCTGCTGTATCGCTGGCGCTG
ATCATCGGCATTCCGGTGGGCATCCTTGCGGCACGGCGCGAAACCACCGCCCGGCGGATGTTGCTGGTCTGTGATACAGC
GCAGACCTTCCCCAGCTTCATCTACCTGATCCCGGCGATCATGCTGTTCGGCATCACGGCCACCTCGGTTGTCATGTCGA
TCCTGATCTTCGCCATGGTGCCACTGGTGCGCTATACCATCGAAGGTTTGCGCAGCGTACCCGCCGAAATGATGGAAGCC
GCCGACATGTCGGGCGCAACCAAGCTGCAAAAGCTGTGGCAGGTGCAACTGCCGCTGGCGCTGCCGACGATGGCCGTGGG
CTTTAATCAGGCGATCATGTTCGCATTCTTCATGGTCATCATCGCGGCCTTCATCGGCACGCAGGATCTGGGCCAGGAAC
TGCAACGCACGCTGGCCGGGGCCTATCTGGGCAAGAACCTCGTTCTGGGCCTTTGCGTTTCGCTGATGGCGCTGACCTTC
GACATGATTGTCATGAAGTGGGCACAGGAGAAGAAAGCGAAACTGGGGCTGGCGCGTTAA

Upstream 100 bases:

>100_bases
TTGATGACGCGCGGGACGTGATCCCGGTCGCCGATGAAACCGGGCCCATTGGTGCCATGGCGCGTAAAGATGCGCTTGAT
ATCCTGTTGCAGGCGAACTG

Downstream 100 bases:

>100_bases
AGCGTCCTGCGAAACAGCTGCCTCACCCACCGCATTCCGAAACCAAGGGTTTCAACGCGGTGGGTGATACTTGATGTTTC
AGGTATTTCGTCAGGCGCCC

Product: glycine betaine transporter, permease protein

Products: ADP; phosphate; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 659; Mature: 658

Protein sequence:

>659_residues
MAIVATNTESQTTPLSSRTLGLGLFLFAVALTLLHYAGLLPAWLHRLPEAVIPPFETWLDAIFNFVKDDLGLLALTRFLT
GGLEAVLDVTANLLYGKRRWPFIDPIPWSAIAAATTVLGYYLGGWRLAALAGGTCVWTAMIGQWEIAMETMSVLVISAPL
AFMIGLLVGIYAWKSPSFNRALLPFLSVMQTLPFFTYLLPAVIFFKVGPTAAAVATTVFAIPPMILMTTLGLQKVSSEVV
EAGKMSGCTRFQMMRHVYLPSARTEILVGVNQVIMLCLAMVVLTAFIGMPGLGAKLLQMLGSFKIGRAFEIGVTIVLVAI
TLDRLSKAWVAKLPEHFDRGTPFYIRHKYLVAGAVGFALFFALAQLVPILAEVGRRQSLSQGREIDQLIKAYLALDWVKA
STDAMRYVLNVWILNPFRDFLLSIPTSAFIILVVAAGLVIAGPRQAVLAAVFFSLVALSGWWDRSVITLYSVIAAVSLAL
IIGIPVGILAARRETTARRMLLVCDTAQTFPSFIYLIPAIMLFGITATSVVMSILIFAMVPLVRYTIEGLRSVPAEMMEA
ADMSGATKLQKLWQVQLPLALPTMAVGFNQAIMFAFFMVIIAAFIGTQDLGQELQRTLAGAYLGKNLVLGLCVSLMALTF
DMIVMKWAQEKKAKLGLAR

Sequences:

>Translated_659_residues
MAIVATNTESQTTPLSSRTLGLGLFLFAVALTLLHYAGLLPAWLHRLPEAVIPPFETWLDAIFNFVKDDLGLLALTRFLT
GGLEAVLDVTANLLYGKRRWPFIDPIPWSAIAAATTVLGYYLGGWRLAALAGGTCVWTAMIGQWEIAMETMSVLVISAPL
AFMIGLLVGIYAWKSPSFNRALLPFLSVMQTLPFFTYLLPAVIFFKVGPTAAAVATTVFAIPPMILMTTLGLQKVSSEVV
EAGKMSGCTRFQMMRHVYLPSARTEILVGVNQVIMLCLAMVVLTAFIGMPGLGAKLLQMLGSFKIGRAFEIGVTIVLVAI
TLDRLSKAWVAKLPEHFDRGTPFYIRHKYLVAGAVGFALFFALAQLVPILAEVGRRQSLSQGREIDQLIKAYLALDWVKA
STDAMRYVLNVWILNPFRDFLLSIPTSAFIILVVAAGLVIAGPRQAVLAAVFFSLVALSGWWDRSVITLYSVIAAVSLAL
IIGIPVGILAARRETTARRMLLVCDTAQTFPSFIYLIPAIMLFGITATSVVMSILIFAMVPLVRYTIEGLRSVPAEMMEA
ADMSGATKLQKLWQVQLPLALPTMAVGFNQAIMFAFFMVIIAAFIGTQDLGQELQRTLAGAYLGKNLVLGLCVSLMALTF
DMIVMKWAQEKKAKLGLAR
>Mature_658_residues
AIVATNTESQTTPLSSRTLGLGLFLFAVALTLLHYAGLLPAWLHRLPEAVIPPFETWLDAIFNFVKDDLGLLALTRFLTG
GLEAVLDVTANLLYGKRRWPFIDPIPWSAIAAATTVLGYYLGGWRLAALAGGTCVWTAMIGQWEIAMETMSVLVISAPLA
FMIGLLVGIYAWKSPSFNRALLPFLSVMQTLPFFTYLLPAVIFFKVGPTAAAVATTVFAIPPMILMTTLGLQKVSSEVVE
AGKMSGCTRFQMMRHVYLPSARTEILVGVNQVIMLCLAMVVLTAFIGMPGLGAKLLQMLGSFKIGRAFEIGVTIVLVAIT
LDRLSKAWVAKLPEHFDRGTPFYIRHKYLVAGAVGFALFFALAQLVPILAEVGRRQSLSQGREIDQLIKAYLALDWVKAS
TDAMRYVLNVWILNPFRDFLLSIPTSAFIILVVAAGLVIAGPRQAVLAAVFFSLVALSGWWDRSVITLYSVIAAVSLALI
IGIPVGILAARRETTARRMLLVCDTAQTFPSFIYLIPAIMLFGITATSVVMSILIFAMVPLVRYTIEGLRSVPAEMMEAA
DMSGATKLQKLWQVQLPLALPTMAVGFNQAIMFAFFMVIIAAFIGTQDLGQELQRTLAGAYLGKNLVLGLCVSLMALTFD
MIVMKWAQEKKAKLGLAR

Specific function: Involved in a multicomponent binding-protein-dependent transport system for glycine betaine; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4176

COG function: function code E; ABC-type proline/glycine betaine transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789033, Length=284, Percent_Identity=33.8028169014084, Blast_Score=140, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 71850; Mature: 71719

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIVATNTESQTTPLSSRTLGLGLFLFAVALTLLHYAGLLPAWLHRLPEAVIPPFETWLD
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHH
AIFNFVKDDLGLLALTRFLTGGLEAVLDVTANLLYGKRRWPFIDPIPWSAIAAATTVLGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
YLGGWRLAALAGGTCVWTAMIGQWEIAMETMSVLVISAPLAFMIGLLVGIYAWKSPSFNR
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
ALLPFLSVMQTLPFFTYLLPAVIFFKVGPTAAAVATTVFAIPPMILMTTLGLQKVSSEVV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAGKMSGCTRFQMMRHVYLPSARTEILVGVNQVIMLCLAMVVLTAFIGMPGLGAKLLQML
HHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
GSFKIGRAFEIGVTIVLVAITLDRLSKAWVAKLPEHFDRGTPFYIRHKYLVAGAVGFALF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHH
FALAQLVPILAEVGRRQSLSQGREIDQLIKAYLALDWVKASTDAMRYVLNVWILNPFRDF
HHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSIPTSAFIILVVAAGLVIAGPRQAVLAAVFFSLVALSGWWDRSVITLYSVIAAVSLAL
HHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
IIGIPVGILAARRETTARRMLLVCDTAQTFPSFIYLIPAIMLFGITATSVVMSILIFAMV
HHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLVRYTIEGLRSVPAEMMEAADMSGATKLQKLWQVQLPLALPTMAVGFNQAIMFAFFMVI
HHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IAAFIGTQDLGQELQRTLAGAYLGKNLVLGLCVSLMALTFDMIVMKWAQEKKAKLGLAR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AIVATNTESQTTPLSSRTLGLGLFLFAVALTLLHYAGLLPAWLHRLPEAVIPPFETWLD
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHH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HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-proline [Periplasm]; H2O [C]

Specific reaction: ATP + L-proline [Periplasm] + H2O = ADP + phosphate + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7622480; 8969502; 9384377 [H]