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The map label for this gene is yadA [H]

Identifier: 108813262

GI number: 108813262

Start: 3485142

End: 3487082

Strand: Reverse

Name: yadA [H]

Synonym: YPN_3102

Alternate gene names: 108813262

Gene position: 3487082-3485142 (Counterclockwise)

Preceding gene: 108813263

Following gene: 108813261

Centisome position: 76.9

GC content: 54.4

Gene sequence:

>1941_bases
ATGGATGGGCCGTCGGTGGGGCCTATAACTAGTCCGAATTGTAATACTCCATCTATTGGGATTATTAATACAAATGCGGG
GCAGCTATTTGTTGGTGGAACGGGGGCTGCGGTATCGGGAACATTAGGCCCTACTTTTTGGACAGGGACATTTGCTACAC
CGGTCGGCACCAGTAATACCGCAACTGCATACGGTATGGTCGTTCAAAGCGGTGGTGCGTACATCACGGGTAATACTTAC
GTACAAGGTGGGTTATTCTTGAATGGGCAAAAAGCGACCAATCTTGCCCCTGCGACGATTTCATCTACCTCTACCGATGC
GGTAGTTGGTAGCCAGCTTTATAATCTGGTCCAAGATGGAACCCGCTATTTCCATGCTAACTCAGTGAATCCAACAGACT
CACTGGCCTCTGGCCTGGAAACCATTGCTGTCGGGCCAGCGACAGTGGTCAGTGGAGATAACGGTGTTGGCATTGGTAAC
ACCGCCCTTGTCGGGGCGGCAGCAACGGGGGGAATTGCAATAGGTTTCGGTACTCAGGTGACAGCTGCCGGGGCTACGGC
CATCGGTTCCGCAGCGCAGGCTCAAGGGGCGCAATCTCTGGCGTTAGGCGCGGGGGCGGTGACCAGCCAGGCAAACAGTA
TCGCGTTGGGGGCTGCTTCGATCAATACGGTCGGCGCTCAGAGCAGTTACAGTGCTTATGCACTAACGGCTCCGCAGGCA
TCGGTGGGGGAGTTAGGGATTGGCACCGCATTGGGTAATCGTAAGATTACCGGTGTCGCAGCTGGATCGGCGAGTTCTGA
TGCGGTCAATGTTGCTCAGTTGACTGCTGTTGGTGATCAGGTGCAGCAGAATACCGCGAACATCACCAGCCTGGGTGGCC
GGGTTACCACCATTGAGGGGAGCATGGCCAGCATCGCCAATGGTGGCGGTGTGAAGTATTTCCATGCCAACTCGACTCAG
CCTGACTCGGTAGCCAGTGGTACCAATTCGGTGGCCATCGGGCCTGCTTCTCTGGCTTCGGGTAATGCTGCTTTGGCTTC
GGGGGCAGGGGCGGTGGCGATAGGGGATGGTGCTGCCGCCAGCGCGGACGGCAGTGTTGCCATTGGTCAGGGATCTGGTG
ATAACGGGCGTGGCGTAGAGAACTACATCGGTAAGTATTCCAATGCGAGTAACACCAGCTCGGGTACCGTATCAGTGGGT
AATACTGCTACTGGAGAAACCCGGACGGTCAGCAATGTTGCCGATGGGCTGCAGGCCACCGATGCGGTCAATTTGCGACA
ACTCGATGGTATTGCTGCCTCTATCGTCGTCGTCGAAAACAACGTTTCTGGGCTCCAGAATGGTACCGATGGTATGTTTC
AGGTGAATAATAGTAGCGGTCTTGCCAAGCCATCCGCAACCGGTGCTAATTCAGCAACTGGTGGTGCCGGTTCTGTGGCT
TCCGGCAATAACAGTACCGCGTTTGGCTCAGGTGCTAAAGCAACAGCGGCAAACAGTGCAGCCTTGGGGGCTAACTCAGT
AGCTGATCGGGCAAACAGTGTTTCGGTAGGCTCTGTTGGTAATGAACGGCAGATCACCAACGTCGCCCCCGCAACTCAGG
GAACCGACGCGGTGAACTTCGATCAACTTAAGAGCATTTCCAATCAAACTAATGCTTACACGAACCAACGTTATTCCGAG
CTGAAGCAGGATCTGAGGAAACAAAATAGCGTGTTGAGTGCAGGGATAGCTAGCGCAATGTCTATGGCGAGCTTGACACA
ACCATATACTTCGGGTTCCAGCATGACCACTATCGGCGCGGCCAGTTACCGTGGTCAATCGGCTCTGTCGCTAGGGGTAT
CGAGTATTTCTGACAGCGGGAGATGGGTCAGCAAACTACAGGCATCCTCTAACACTCAAGGTGATTTTGGGATTGGTGTC
GGTGTAGGGTATCAGTGGTAA

Upstream 100 bases:

>100_bases
GTCTGTTTAGTATTTCTATAGTGATGATTTATTTATCCCTGGCACCGCAACTTCTCAGCTTTATGTGAATAATGCTGATG
ATCAGTCTTGTTATGCCATT

Downstream 100 bases:

>100_bases
AGAGCGCGTTACGCCAACGCTGAATGCTATTCAGGCTGTCACTAACGGGTTGTAGGGTGTTTTGTACAACCCGATTCTCG
CTCTTGGGCATCAAAGGATC

Product: surface protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 646; Mature: 646

Protein sequence:

>646_residues
MDGPSVGPITSPNCNTPSIGIINTNAGQLFVGGTGAAVSGTLGPTFWTGTFATPVGTSNTATAYGMVVQSGGAYITGNTY
VQGGLFLNGQKATNLAPATISSTSTDAVVGSQLYNLVQDGTRYFHANSVNPTDSLASGLETIAVGPATVVSGDNGVGIGN
TALVGAAATGGIAIGFGTQVTAAGATAIGSAAQAQGAQSLALGAGAVTSQANSIALGAASINTVGAQSSYSAYALTAPQA
SVGELGIGTALGNRKITGVAAGSASSDAVNVAQLTAVGDQVQQNTANITSLGGRVTTIEGSMASIANGGGVKYFHANSTQ
PDSVASGTNSVAIGPASLASGNAALASGAGAVAIGDGAAASADGSVAIGQGSGDNGRGVENYIGKYSNASNTSSGTVSVG
NTATGETRTVSNVADGLQATDAVNLRQLDGIAASIVVVENNVSGLQNGTDGMFQVNNSSGLAKPSATGANSATGGAGSVA
SGNNSTAFGSGAKATAANSAALGANSVADRANSVSVGSVGNERQITNVAPATQGTDAVNFDQLKSISNQTNAYTNQRYSE
LKQDLRKQNSVLSAGIASAMSMASLTQPYTSGSSMTTIGAASYRGQSALSLGVSSISDSGRWVSKLQASSNTQGDFGIGV
GVGYQW

Sequences:

>Translated_646_residues
MDGPSVGPITSPNCNTPSIGIINTNAGQLFVGGTGAAVSGTLGPTFWTGTFATPVGTSNTATAYGMVVQSGGAYITGNTY
VQGGLFLNGQKATNLAPATISSTSTDAVVGSQLYNLVQDGTRYFHANSVNPTDSLASGLETIAVGPATVVSGDNGVGIGN
TALVGAAATGGIAIGFGTQVTAAGATAIGSAAQAQGAQSLALGAGAVTSQANSIALGAASINTVGAQSSYSAYALTAPQA
SVGELGIGTALGNRKITGVAAGSASSDAVNVAQLTAVGDQVQQNTANITSLGGRVTTIEGSMASIANGGGVKYFHANSTQ
PDSVASGTNSVAIGPASLASGNAALASGAGAVAIGDGAAASADGSVAIGQGSGDNGRGVENYIGKYSNASNTSSGTVSVG
NTATGETRTVSNVADGLQATDAVNLRQLDGIAASIVVVENNVSGLQNGTDGMFQVNNSSGLAKPSATGANSATGGAGSVA
SGNNSTAFGSGAKATAANSAALGANSVADRANSVSVGSVGNERQITNVAPATQGTDAVNFDQLKSISNQTNAYTNQRYSE
LKQDLRKQNSVLSAGIASAMSMASLTQPYTSGSSMTTIGAASYRGQSALSLGVSSISDSGRWVSKLQASSNTQGDFGIGV
GVGYQW
>Mature_646_residues
MDGPSVGPITSPNCNTPSIGIINTNAGQLFVGGTGAAVSGTLGPTFWTGTFATPVGTSNTATAYGMVVQSGGAYITGNTY
VQGGLFLNGQKATNLAPATISSTSTDAVVGSQLYNLVQDGTRYFHANSVNPTDSLASGLETIAVGPATVVSGDNGVGIGN
TALVGAAATGGIAIGFGTQVTAAGATAIGSAAQAQGAQSLALGAGAVTSQANSIALGAASINTVGAQSSYSAYALTAPQA
SVGELGIGTALGNRKITGVAAGSASSDAVNVAQLTAVGDQVQQNTANITSLGGRVTTIEGSMASIANGGGVKYFHANSTQ
PDSVASGTNSVAIGPASLASGNAALASGAGAVAIGDGAAASADGSVAIGQGSGDNGRGVENYIGKYSNASNTSSGTVSVG
NTATGETRTVSNVADGLQATDAVNLRQLDGIAASIVVVENNVSGLQNGTDGMFQVNNSSGLAKPSATGANSATGGAGSVA
SGNNSTAFGSGAKATAANSAALGANSVADRANSVSVGSVGNERQITNVAPATQGTDAVNFDQLKSISNQTNAYTNQRYSE
LKQDLRKQNSVLSAGIASAMSMASLTQPYTSGSSMTTIGAASYRGQSALSLGVSSISDSGRWVSKLQASSNTQGDFGIGV
GVGYQW

Specific function: Collagen-binding outer membrane protein forming a fibrillar matrix on the bacterial cell surface. Promotes initial attachment and invasion of eukaryotic cells. Also protects the bacteria by being responsible for agglutination, serum resistance, complement

COG id: COG5295

COG function: function code UW; Autotransporter adhesin

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the autotransporter-2 (TC 1.B.40) / oligomeric coiled-coil adhesin (Oca) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008640
- InterPro:   IPR008635
- InterPro:   IPR008126
- InterPro:   IPR005594 [H]

Pfam domain/function: PF05658 Hep_Hag; PF05662 HIM; PF03895 YadA [H]

EC number: NA

Molecular weight: Translated: 62550; Mature: 62550

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGPSVGPITSPNCNTPSIGIINTNAGQLFVGGTGAAVSGTLGPTFWTGTFATPVGTSNT
CCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCEEECCCCCCEECCCEECCCCCCCC
ATAYGMVVQSGGAYITGNTYVQGGLFLNGQKATNLAPATISSTSTDAVVGSQLYNLVQDG
CEEEEEEEECCCCEEECCEEEECCEEECCCCCCCCCCCEECCCCCHHHHHHHHHHHHHCC
TRYFHANSVNPTDSLASGLETIAVGPATVVSGDNGVGIGNTALVGAAATGGIAIGFGTQV
CEEEECCCCCCHHHHHHCCCEEECCCEEEEECCCCCCCCCCEEEEEECCCCEEEECCCEE
TAAGATAIGSAAQAQGAQSLALGAGAVTSQANSIALGAASINTVGAQSSYSAYALTAPQA
EECCHHHHCCHHHHCCCCCEEECCCHHHCCCCEEEEECCCCCCCCCCCCCCEEEEECCCC
SVGELGIGTALGNRKITGVAAGSASSDAVNVAQLTAVGDQVQQNTANITSLGGRVTTIEG
CCCCCCCEEECCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHCCCCHHHCCCEEEEECC
SMASIANGGGVKYFHANSTQPDSVASGTNSVAIGPASLASGNAALASGAGAVAIGDGAAA
CHHHHCCCCCEEEEECCCCCCCHHHCCCCCEEECCHHHCCCCEEEECCCCEEEECCCCCC
SADGSVAIGQGSGDNGRGVENYIGKYSNASNTSSGTVSVGNTATGETRTVSNVADGLQAT
CCCCCEEEECCCCCCCCCHHHHHHCCCCCCCCCCCEEEECCCCCCCCEEHHHHHCCHHHC
DAVNLRQLDGIAASIVVVENNVSGLQNGTDGMFQVNNSSGLAKPSATGANSATGGAGSVA
CCCCHHHHCCCEEEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
SGNNSTAFGSGAKATAANSAALGANSVADRANSVSVGSVGNERQITNVAPATQGTDAVNF
CCCCCCCCCCCCCCCCCCCHHCCCCHHHHCCCCEEECCCCCCCEEEECCCCCCCCCCCCH
DQLKSISNQTNAYTNQRYSELKQDLRKQNSVLSAGIASAMSMASLTQPYTSGSSMTTIGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEC
ASYRGQSALSLGVSSISDSGRWVSKLQASSNTQGDFGIGVGVGYQW
CCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MDGPSVGPITSPNCNTPSIGIINTNAGQLFVGGTGAAVSGTLGPTFWTGTFATPVGTSNT
CCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCEEECCCCCCEECCCEECCCCCCCC
ATAYGMVVQSGGAYITGNTYVQGGLFLNGQKATNLAPATISSTSTDAVVGSQLYNLVQDG
CEEEEEEEECCCCEEECCEEEECCEEECCCCCCCCCCCEECCCCCHHHHHHHHHHHHHCC
TRYFHANSVNPTDSLASGLETIAVGPATVVSGDNGVGIGNTALVGAAATGGIAIGFGTQV
CEEEECCCCCCHHHHHHCCCEEECCCEEEEECCCCCCCCCCEEEEEECCCCEEEECCCEE
TAAGATAIGSAAQAQGAQSLALGAGAVTSQANSIALGAASINTVGAQSSYSAYALTAPQA
EECCHHHHCCHHHHCCCCCEEECCCHHHCCCCEEEEECCCCCCCCCCCCCCEEEEECCCC
SVGELGIGTALGNRKITGVAAGSASSDAVNVAQLTAVGDQVQQNTANITSLGGRVTTIEG
CCCCCCCEEECCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHCCCCHHHCCCEEEEECC
SMASIANGGGVKYFHANSTQPDSVASGTNSVAIGPASLASGNAALASGAGAVAIGDGAAA
CHHHHCCCCCEEEEECCCCCCCHHHCCCCCEEECCHHHCCCCEEEECCCCEEEECCCCCC
SADGSVAIGQGSGDNGRGVENYIGKYSNASNTSSGTVSVGNTATGETRTVSNVADGLQAT
CCCCCEEEECCCCCCCCCHHHHHHCCCCCCCCCCCEEEECCCCCCCCEEHHHHHCCHHHC
DAVNLRQLDGIAASIVVVENNVSGLQNGTDGMFQVNNSSGLAKPSATGANSATGGAGSVA
CCCCHHHHCCCEEEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
SGNNSTAFGSGAKATAANSAALGANSVADRANSVSVGSVGNERQITNVAPATQGTDAVNF
CCCCCCCCCCCCCCCCCCCHHCCCCHHHHCCCCEEECCCCCCCEEEECCCCCCCCCCCCH
DQLKSISNQTNAYTNQRYSELKQDLRKQNSVLSAGIASAMSMASLTQPYTSGSSMTTIGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEC
ASYRGQSALSLGVSSISDSGRWVSKLQASSNTQGDFGIGVGVGYQW
CCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14527656; 2592347 [H]