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The map label for this gene is skp [H]

Identifier: 108813107

GI number: 108813107

Start: 3307446

End: 3307994

Strand: Reverse

Name: skp [H]

Synonym: YPN_2947

Alternate gene names: 108813107

Gene position: 3307994-3307446 (Counterclockwise)

Preceding gene: 108813108

Following gene: 108813106

Centisome position: 72.95

GC content: 44.99

Gene sequence:

>549_bases
GTGCAATTCAAGGTGTCTCTGACACAAACGGGTAATGGTAAGGAGTTTATAGTGAAAAAGTGGTTGTGTGCCGCAAGTCT
AGGTTTAGCATTGGCTGCTTCAGCCAGCGTTCAAGCAGCTGACAAAATTGCTATTGTTAATGTTTCCAGCATTTTCCAAC
AATTACCCGCGCGTGAAGCCGTGGCTAAGCAGCTGGAGAATGAATTCAAAGGCCGTGCAACCGAACTGCAAGGAATGGAG
CGCGATCTGCAGACTAAAATGCAGAAGCTACAACGTGATGGTTCTACCATGAAAGCCAGTGATCGTACCAAGCTGGAAAA
TGAAGTAATGAAACAGCGTGAAACTTTCTCTACTAAAGCGCAGGCTTTTGAGCAAGATAACCGCCGTCGTCAGGCAGAAG
AGCGTAACAAAATCCTGAGCCGTATTCAGGATGCTGTTAAATCTGTTGCTACCAAAGGTGGCTATGACGTAGTCATTGAT
GCGAATGCAGTGGCATACGCTGATTCTTCTAAAGACATTACTGCTGACGTATTGAAACAGGTTAAATAA

Upstream 100 bases:

>100_bases
GGCAAAGCAGTTCTGAATTTTAAAGACAGCACTGGTAGTGAAAGGATCTTAAGTCGCGTTGGTGAAATCTGACGCTTCAT
CAGGTGGGATACACTACCAA

Downstream 100 bases:

>100_bases
AACATGCCTTCAATTCGACTGGCTGATTTAGCCCAGCAGTTGGATGCACAGGTGCACGGTGATGGCGATCTTGTCATCAC
CGGCATCGCTTCTATGCATT

Product: periplasmic chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MQFKVSLTQTGNGKEFIVKKWLCAASLGLALAASASVQAADKIAIVNVSSIFQQLPAREAVAKQLENEFKGRATELQGME
RDLQTKMQKLQRDGSTMKASDRTKLENEVMKQRETFSTKAQAFEQDNRRRQAEERNKILSRIQDAVKSVATKGGYDVVID
ANAVAYADSSKDITADVLKQVK

Sequences:

>Translated_182_residues
MQFKVSLTQTGNGKEFIVKKWLCAASLGLALAASASVQAADKIAIVNVSSIFQQLPAREAVAKQLENEFKGRATELQGME
RDLQTKMQKLQRDGSTMKASDRTKLENEVMKQRETFSTKAQAFEQDNRRRQAEERNKILSRIQDAVKSVATKGGYDVVID
ANAVAYADSSKDITADVLKQVK
>Mature_182_residues
MQFKVSLTQTGNGKEFIVKKWLCAASLGLALAASASVQAADKIAIVNVSSIFQQLPAREAVAKQLENEFKGRATELQGME
RDLQTKMQKLQRDGSTMKASDRTKLENEVMKQRETFSTKAQAFEQDNRRRQAEERNKILSRIQDAVKSVATKGGYDVVID
ANAVAYADSSKDITADVLKQVK

Specific function: Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm [H]

COG id: COG2825

COG function: function code M; Outer membrane protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the skp family [H]

Homologues:

Organism=Escherichia coli, GI1786375, Length=167, Percent_Identity=67.065868263473, Blast_Score=177, Evalue=2e-46,

Paralogues:

None

Copy number: 580 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005632 [H]

Pfam domain/function: PF03938 OmpH [H]

EC number: NA

Molecular weight: Translated: 20157; Mature: 20157

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFKVSLTQTGNGKEFIVKKWLCAASLGLALAASASVQAADKIAIVNVSSIFQQLPAREA
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEEHHHHHHHCCHHHH
VAKQLENEFKGRATELQGMERDLQTKMQKLQRDGSTMKASDRTKLENEVMKQRETFSTKA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QAFEQDNRRRQAEERNKILSRIQDAVKSVATKGGYDVVIDANAVAYADSSKDITADVLKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEECCCCCCHHHHHHHH
VK
CC
>Mature Secondary Structure
MQFKVSLTQTGNGKEFIVKKWLCAASLGLALAASASVQAADKIAIVNVSSIFQQLPAREA
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEEHHHHHHHCCHHHH
VAKQLENEFKGRATELQGMERDLQTKMQKLQRDGSTMKASDRTKLENEVMKQRETFSTKA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QAFEQDNRRRQAEERNKILSRIQDAVKSVATKGGYDVVIDANAVAYADSSKDITADVLKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEECCCCCCHHHHHHHH
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]