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The map label for this gene is mrkC [H]

Identifier: 108812083

GI number: 108812083

Start: 2166217

End: 2168829

Strand: Reverse

Name: mrkC [H]

Synonym: YPN_1921

Alternate gene names: 108812083

Gene position: 2168829-2166217 (Counterclockwise)

Preceding gene: 108812084

Following gene: 108812082

Centisome position: 47.83

GC content: 49.33

Gene sequence:

>2613_bases
ATGCTTAGTGCTTTCATATTTTTTCAAAAAAACGAGTGCCTAAAATATTTACCGGCATTCTCTTTCGCTATTTGTGGTAT
TGGTGGCATGTTATATATTCCGTCATCTGCCGCCGAGAATTCTGAATACGTTGAATTTAGTGACGCCTTCCTCCGTTTTC
CCGTTGATGCCACCCGCTACAGTGAGGGTAATCCTGTTTCCCCCGGTGAGCGTCAGGTTGATATCTATTTAAATGATCAA
TGGATTGGTCGTCAGGAAATGCGTTTTGCCTTGCCGTCGCCAGAATCGAAAGTTGCCACCCCCTGTTTTGACGTAAAACT
CTTTGATGAGTTGGGGGTTGATACGGCGAAGTTATCTTCCGATACCGTGAAATTGCTCGAAAGTCGCGGGGCATGCTCTC
CGTTGAGTCGTTTGCTGGAAGGTGGAAATGCTATTTTCGACGACAATCAGCAACGCTTGGATATTCAGGTTCCTCAAGCT
TATCTGATCCGCCAGGCTTGCGGTTATGTGCATCCTAAATATTGGGATGATGGCGTGACAGCGGCCACCTTGAAATATGA
CTATACCGGTTACCGCAGTAACCAGAATGATATCGGTAGCCAGACTTATCAATATCTGGGGCTCTTGGGCGGGCTTAACT
GGCAAAGCTGGCGTCTATATTACCGCAGTGCATTGAATCGAAGTGATAGCCAAGGCTTTGATTATCAGAACCTGGCCACT
TATGTTGAACGGGCCGTTCCCTCGCTATACAGCAAAATGACTATTGGTGATTCAAACACGGATGGTCAGGTGTTCGACAG
CCTTAGCTATCGCGGCATTGAGTTGACCTCAGATGACCGGATGTATGCGGATTCTCAGCGGGGTTATGCGCCAGTGGTAC
GGGGTGTTGCTCGAACGAACGCCCGCGTCGTGGTGCGTCAACAGGGGCGGCCTATTTATGAAACGACGGTACCCCCAGGG
CCTTTTGTCATTGACGACCTCTACCCGACCGGTCAGGGGGGCAATCTCAATGTCACCATTACCGAAGCGGATGGCAGCGA
ACAGACATTTATCGTTCCTTTTGCCTCGATAGCGGAGTTGCTGCGACCGGGAACCACGCGTTACTCATTGATGGCCGGTG
AGTATCGTGACAATTCGATGGTAGATAAACCGGTCCTCTTTATGGGAACGGTGCGTCATGGGTTATCCAATTTACTCACC
GGTAACGGCGGGATGGTTGCGGCTGAAGGCTATTTATCAGCCTCTGCCGGGCTGGCATTTAACACACCAGTTGGTGCAGT
GGCATTTAATGTGACGCAAGCACAAACCCGTCTGCCTAATAAAGATAATCAACGTGGGCAAAGTATTGGTATGACCTATG
CTAAATCCTTGCCGGAAACCAATACCAACTTGACCATCGCCAGTTATCACTATTCCAGTAACGGTTTTTATACACCAGCA
GAAGCTATGCGAATGCGTGATTATTTACAGCATGGTGAAGTCAATAATACGCAGATTGATTCAAGTTGGCCGAATGGCAG
TGATCGCTACGATGATAGTTTTAAGTATCGTCGCCGCAATCAGGCGCAAGTGAGTATCGCTCAGGGCTTACCTGATGGCT
ATGGCTCGTTCTACGCAAATGCCAATGTGCAGGATTACTGGGATGGACGTAACCGCGATATGAATTTTCAATTCGGCTAC
ACGAATAGCTATAAGTCGCTGAGTTATAACGTGGCGCTTAATCGCTTGCGTGATATACCTAGCGGCGATTGGGACAACCA
ATTAAGTGTTTCCCTTTCGATTCCTCTGGGGACACATGCTGGTGCACCACGTTTGAGCTCCAGTTATTCCAATACTCGTG
GTAGCAGTGCAATACAAACCGGGGTTTCCGGCTCTGCGGGTGAGGATAATCAATTTAGCTATGGCGTATCTGCAGCGAAT
AACCGTAGCGATGAAAATGGCAGTTATAACACCCTAGGTGCGAATGGCAGTTGGCAGGCACCTTACGCCACGGTGGGCGG
TAGTTATTCGAAGAGTAACAGCTATGATCAAGCCAGTGCCAGCTTGTCAGGGGGGGTAGTGGCTTATCGTGGTGGGGTGA
TATTGGCCCCTGCACTGGGTGATACCGTCGGTATTATTGAGGCTCCAGATGCTGCGGGAGCGCGTGTCGGCAGCTACTCC
AGTATGTATCTTGATCGTCGTGGGCGTGCGATATTGCCTTATTTAAGTCCGTATCGGCAGAATGAGGTTGAATTAGATCC
GAAAGGGCTATCTGCAGATGTTGAGTTTAAAAGTACTAGCCAAAAAGTTGCGCCAACCGCAGGTGCTGTTGCATTGGTAA
CATTCGAGACCTCAACCGGTTATTCGGTTTTAGTCAGGGGGCATCTGGCAGATAACACCCCCTTGCCGTTTGGGGCGGAA
GTAAAAGATGGCGGAGGGACCCGCGTCGGCTTTATTGCTCAGGGCGGTCAGGCAATGGTCCGAGTGAATCAACAAGCCGG
TAATCTGCGCGTGATATGGGGTGATGGCATCGGTGAGAGTTGCAGTTTTGACTATAAATTGCCGGAAGGTAACCTAGTAA
AAGGTCATCTGGTCAAAGGTGACTACCGGCGCTTAGAGGTGATATGCAAATGA

Upstream 100 bases:

>100_bases
GCAAAAACTGACCCAATAAAACTATAAAAAATACAAATTAAGGGTAATTTGTATTTTTTGCACTTTTATATACTGCATTT
AATTTAATGGCCTCGATATA

Downstream 100 bases:

>100_bases
GTGCTTATTTCTATAGGGTGAAAACAGTGATTCGGCATATCAACATGTACCTGCGCGTTTATGCTCATGTCCGTTCTGTT
GCTACGCTACTGATATTGGT

Product: outer membrane usher protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 870; Mature: 870

Protein sequence:

>870_residues
MLSAFIFFQKNECLKYLPAFSFAICGIGGMLYIPSSAAENSEYVEFSDAFLRFPVDATRYSEGNPVSPGERQVDIYLNDQ
WIGRQEMRFALPSPESKVATPCFDVKLFDELGVDTAKLSSDTVKLLESRGACSPLSRLLEGGNAIFDDNQQRLDIQVPQA
YLIRQACGYVHPKYWDDGVTAATLKYDYTGYRSNQNDIGSQTYQYLGLLGGLNWQSWRLYYRSALNRSDSQGFDYQNLAT
YVERAVPSLYSKMTIGDSNTDGQVFDSLSYRGIELTSDDRMYADSQRGYAPVVRGVARTNARVVVRQQGRPIYETTVPPG
PFVIDDLYPTGQGGNLNVTITEADGSEQTFIVPFASIAELLRPGTTRYSLMAGEYRDNSMVDKPVLFMGTVRHGLSNLLT
GNGGMVAAEGYLSASAGLAFNTPVGAVAFNVTQAQTRLPNKDNQRGQSIGMTYAKSLPETNTNLTIASYHYSSNGFYTPA
EAMRMRDYLQHGEVNNTQIDSSWPNGSDRYDDSFKYRRRNQAQVSIAQGLPDGYGSFYANANVQDYWDGRNRDMNFQFGY
TNSYKSLSYNVALNRLRDIPSGDWDNQLSVSLSIPLGTHAGAPRLSSSYSNTRGSSAIQTGVSGSAGEDNQFSYGVSAAN
NRSDENGSYNTLGANGSWQAPYATVGGSYSKSNSYDQASASLSGGVVAYRGGVILAPALGDTVGIIEAPDAAGARVGSYS
SMYLDRRGRAILPYLSPYRQNEVELDPKGLSADVEFKSTSQKVAPTAGAVALVTFETSTGYSVLVRGHLADNTPLPFGAE
VKDGGGTRVGFIAQGGQAMVRVNQQAGNLRVIWGDGIGESCSFDYKLPEGNLVKGHLVKGDYRRLEVICK

Sequences:

>Translated_870_residues
MLSAFIFFQKNECLKYLPAFSFAICGIGGMLYIPSSAAENSEYVEFSDAFLRFPVDATRYSEGNPVSPGERQVDIYLNDQ
WIGRQEMRFALPSPESKVATPCFDVKLFDELGVDTAKLSSDTVKLLESRGACSPLSRLLEGGNAIFDDNQQRLDIQVPQA
YLIRQACGYVHPKYWDDGVTAATLKYDYTGYRSNQNDIGSQTYQYLGLLGGLNWQSWRLYYRSALNRSDSQGFDYQNLAT
YVERAVPSLYSKMTIGDSNTDGQVFDSLSYRGIELTSDDRMYADSQRGYAPVVRGVARTNARVVVRQQGRPIYETTVPPG
PFVIDDLYPTGQGGNLNVTITEADGSEQTFIVPFASIAELLRPGTTRYSLMAGEYRDNSMVDKPVLFMGTVRHGLSNLLT
GNGGMVAAEGYLSASAGLAFNTPVGAVAFNVTQAQTRLPNKDNQRGQSIGMTYAKSLPETNTNLTIASYHYSSNGFYTPA
EAMRMRDYLQHGEVNNTQIDSSWPNGSDRYDDSFKYRRRNQAQVSIAQGLPDGYGSFYANANVQDYWDGRNRDMNFQFGY
TNSYKSLSYNVALNRLRDIPSGDWDNQLSVSLSIPLGTHAGAPRLSSSYSNTRGSSAIQTGVSGSAGEDNQFSYGVSAAN
NRSDENGSYNTLGANGSWQAPYATVGGSYSKSNSYDQASASLSGGVVAYRGGVILAPALGDTVGIIEAPDAAGARVGSYS
SMYLDRRGRAILPYLSPYRQNEVELDPKGLSADVEFKSTSQKVAPTAGAVALVTFETSTGYSVLVRGHLADNTPLPFGAE
VKDGGGTRVGFIAQGGQAMVRVNQQAGNLRVIWGDGIGESCSFDYKLPEGNLVKGHLVKGDYRRLEVICK
>Mature_870_residues
MLSAFIFFQKNECLKYLPAFSFAICGIGGMLYIPSSAAENSEYVEFSDAFLRFPVDATRYSEGNPVSPGERQVDIYLNDQ
WIGRQEMRFALPSPESKVATPCFDVKLFDELGVDTAKLSSDTVKLLESRGACSPLSRLLEGGNAIFDDNQQRLDIQVPQA
YLIRQACGYVHPKYWDDGVTAATLKYDYTGYRSNQNDIGSQTYQYLGLLGGLNWQSWRLYYRSALNRSDSQGFDYQNLAT
YVERAVPSLYSKMTIGDSNTDGQVFDSLSYRGIELTSDDRMYADSQRGYAPVVRGVARTNARVVVRQQGRPIYETTVPPG
PFVIDDLYPTGQGGNLNVTITEADGSEQTFIVPFASIAELLRPGTTRYSLMAGEYRDNSMVDKPVLFMGTVRHGLSNLLT
GNGGMVAAEGYLSASAGLAFNTPVGAVAFNVTQAQTRLPNKDNQRGQSIGMTYAKSLPETNTNLTIASYHYSSNGFYTPA
EAMRMRDYLQHGEVNNTQIDSSWPNGSDRYDDSFKYRRRNQAQVSIAQGLPDGYGSFYANANVQDYWDGRNRDMNFQFGY
TNSYKSLSYNVALNRLRDIPSGDWDNQLSVSLSIPLGTHAGAPRLSSSYSNTRGSSAIQTGVSGSAGEDNQFSYGVSAAN
NRSDENGSYNTLGANGSWQAPYATVGGSYSKSNSYDQASASLSGGVVAYRGGVILAPALGDTVGIIEAPDAAGARVGSYS
SMYLDRRGRAILPYLSPYRQNEVELDPKGLSADVEFKSTSQKVAPTAGAVALVTFETSTGYSVLVRGHLADNTPLPFGAE
VKDGGGTRVGFIAQGGQAMVRVNQQAGNLRVIWGDGIGESCSFDYKLPEGNLVKGHLVKGDYRRLEVICK

Specific function: Involved in the export and assembly of the type 3 fimbrial subunit (mrkA) [H]

COG id: COG3188

COG function: function code NU; P pilus assembly protein, porin PapC

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial export usher family [H]

Homologues:

Organism=Escherichia coli, GI1786332, Length=835, Percent_Identity=36.2874251497006, Blast_Score=473, Evalue=1e-134,
Organism=Escherichia coli, GI1790772, Length=812, Percent_Identity=34.4827586206897, Blast_Score=452, Evalue=1e-128,
Organism=Escherichia coli, GI1787172, Length=875, Percent_Identity=34.0571428571429, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI1786744, Length=863, Percent_Identity=31.5179606025492, Blast_Score=421, Evalue=1e-118,
Organism=Escherichia coli, GI1788427, Length=827, Percent_Identity=30.9552599758162, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1789533, Length=802, Percent_Identity=31.0473815461347, Blast_Score=394, Evalue=1e-110,
Organism=Escherichia coli, GI87081778, Length=862, Percent_Identity=28.0742459396752, Blast_Score=252, Evalue=6e-68,
Organism=Escherichia coli, GI1789610, Length=807, Percent_Identity=25.1548946716233, Blast_Score=158, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000015
- InterPro:   IPR018030 [H]

Pfam domain/function: PF00577 Usher [H]

EC number: NA

Molecular weight: Translated: 94866; Mature: 94866

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS01151 FIMBRIAL_USHER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSAFIFFQKNECLKYLPAFSFAICGIGGMLYIPSSAAENSEYVEFSDAFLRFPVDATRY
CCEEEEEEECCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEECCCEEECCCCHHCC
SEGNPVSPGERQVDIYLNDQWIGRQEMRFALPSPESKVATPCFDVKLFDELGVDTAKLSS
CCCCCCCCCCEEEEEEECCCCCCHHHHEEECCCCCCCCCCCEEEEEEHHHCCCCHHHCCH
DTVKLLESRGACSPLSRLLEGGNAIFDDNQQRLDIQVPQAYLIRQACGYVHPKYWDDGVT
HHHHHHHCCCCHHHHHHHHHCCCEEECCCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCE
AATLKYDYTGYRSNQNDIGSQTYQYLGLLGGLNWQSWRLYYRSALNRSDSQGFDYQNLAT
EEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHH
YVERAVPSLYSKMTIGDSNTDGQVFDSLSYRGIELTSDDRMYADSQRGYAPVVRGVARTN
HHHHHHHHHHHEEECCCCCCCCHHHHCCCCCCEEECCCCCEECCCCCCHHHHHHHHHCCC
ARVVVRQQGRPIYETTVPPGPFVIDDLYPTGQGGNLNVTITEADGSEQTFIVPFASIAEL
CEEEEEECCCEEEECCCCCCCEEEECCCCCCCCCEEEEEEEECCCCCCEEEEEHHHHHHH
LRPGTTRYSLMAGEYRDNSMVDKPVLFMGTVRHGLSNLLTGNGGMVAAEGYLSASAGLAF
HCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCEECCCCEEE
NTPVGAVAFNVTQAQTRLPNKDNQRGQSIGMTYAKSLPETNTNLTIASYHYSSNGFYTPA
CCCCCEEEEEEEHHHHCCCCCCCCCCCHHCHHHHHCCCCCCCCEEEEEEEECCCCEECHH
EAMRMRDYLQHGEVNNTQIDSSWPNGSDRYDDSFKYRRRNQAQVSIAQGLPDGYGSFYAN
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCEEEC
ANVQDYWDGRNRDMNFQFGYTNSYKSLSYNVALNRLRDIPSGDWDNQLSVSLSIPLGTHA
CCCHHCCCCCCCCEEEEECCCCCCCCEEEHHHHHHHHCCCCCCCCCEEEEEEEECCCCCC
GAPRLSSSYSNTRGSSAIQTGVSGSAGEDNQFSYGVSAANNRSDENGSYNTLGANGSWQA
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEECCCCCCCC
PYATVGGSYSKSNSYDQASASLSGGVVAYRGGVILAPALGDTVGIIEAPDAAGARVGSYS
CEEECCCCCCCCCCCCHHHHHCCCCEEEEECCEEEEECCCCEEEEEECCCCCCCCCCCCH
SMYLDRRGRAILPYLSPYRQNEVELDPKGLSADVEFKSTSQKVAPTAGAVALVTFETSTG
HEEECCCCCEEECCCCCCCCCCEEECCCCCCEEEEECCCCCCCCCCCCEEEEEEEECCCC
YSVLVRGHLADNTPLPFGAEVKDGGGTRVGFIAQGGQAMVRVNQQAGNLRVIWGDGIGES
EEEEEEEECCCCCCCCCCCEEECCCCCEEEEEECCCEEEEEEECCCCCEEEEECCCCCCC
CSFDYKLPEGNLVKGHLVKGDYRRLEVICK
CEEEEECCCCCEEEEEEECCCCEEEEEEEC
>Mature Secondary Structure
MLSAFIFFQKNECLKYLPAFSFAICGIGGMLYIPSSAAENSEYVEFSDAFLRFPVDATRY
CCEEEEEEECCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEECCCEEECCCCHHCC
SEGNPVSPGERQVDIYLNDQWIGRQEMRFALPSPESKVATPCFDVKLFDELGVDTAKLSS
CCCCCCCCCCEEEEEEECCCCCCHHHHEEECCCCCCCCCCCEEEEEEHHHCCCCHHHCCH
DTVKLLESRGACSPLSRLLEGGNAIFDDNQQRLDIQVPQAYLIRQACGYVHPKYWDDGVT
HHHHHHHCCCCHHHHHHHHHCCCEEECCCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCE
AATLKYDYTGYRSNQNDIGSQTYQYLGLLGGLNWQSWRLYYRSALNRSDSQGFDYQNLAT
EEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHH
YVERAVPSLYSKMTIGDSNTDGQVFDSLSYRGIELTSDDRMYADSQRGYAPVVRGVARTN
HHHHHHHHHHHEEECCCCCCCCHHHHCCCCCCEEECCCCCEECCCCCCHHHHHHHHHCCC
ARVVVRQQGRPIYETTVPPGPFVIDDLYPTGQGGNLNVTITEADGSEQTFIVPFASIAEL
CEEEEEECCCEEEECCCCCCCEEEECCCCCCCCCEEEEEEEECCCCCCEEEEEHHHHHHH
LRPGTTRYSLMAGEYRDNSMVDKPVLFMGTVRHGLSNLLTGNGGMVAAEGYLSASAGLAF
HCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCEECCCCEEE
NTPVGAVAFNVTQAQTRLPNKDNQRGQSIGMTYAKSLPETNTNLTIASYHYSSNGFYTPA
CCCCCEEEEEEEHHHHCCCCCCCCCCCHHCHHHHHCCCCCCCCEEEEEEEECCCCEECHH
EAMRMRDYLQHGEVNNTQIDSSWPNGSDRYDDSFKYRRRNQAQVSIAQGLPDGYGSFYAN
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCEEEC
ANVQDYWDGRNRDMNFQFGYTNSYKSLSYNVALNRLRDIPSGDWDNQLSVSLSIPLGTHA
CCCHHCCCCCCCCEEEEECCCCCCCCEEEHHHHHHHHCCCCCCCCCEEEEEEEECCCCCC
GAPRLSSSYSNTRGSSAIQTGVSGSAGEDNQFSYGVSAANNRSDENGSYNTLGANGSWQA
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEECCCCCCCC
PYATVGGSYSKSNSYDQASASLSGGVVAYRGGVILAPALGDTVGIIEAPDAAGARVGSYS
CEEECCCCCCCCCCCCHHHHHCCCCEEEEECCEEEEECCCCEEEEEECCCCCCCCCCCCH
SMYLDRRGRAILPYLSPYRQNEVELDPKGLSADVEFKSTSQKVAPTAGAVALVTFETSTG
HEEECCCCCEEECCCCCCCCCCEEECCCCCCEEEEECCCCCCCCCCCCEEEEEEEECCCC
YSVLVRGHLADNTPLPFGAEVKDGGGTRVGFIAQGGQAMVRVNQQAGNLRVIWGDGIGES
EEEEEEEECCCCCCCCCCCEEECCCCCEEEEEECCCEEEEEEECCCCCEEEEECCCCCCC
CSFDYKLPEGNLVKGHLVKGDYRRLEVICK
CEEEEECCCCCEEEEEEECCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1670938 [H]