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The map label for this gene is potA2 [H]

Identifier: 108811672

GI number: 108811672

Start: 1711745

End: 1712650

Strand: Reverse

Name: potA2 [H]

Synonym: YPN_1509

Alternate gene names: 108811672

Gene position: 1712650-1711745 (Counterclockwise)

Preceding gene: 108811674

Following gene: 108811671

Centisome position: 37.77

GC content: 53.64

Gene sequence:

>906_bases
TTGGGACCCCCTTTTGATTTCTTGTTGAACATTTGCAGTTGCCAGACCGCAAACTGTTTTAACAAATCAAAAGGGGTTTT
TATAACTGACCCAAAGCTGAAAGCTTTACTGAACCCCCAGCCTAGCTGGGGGTTTTCTGGGCACAAAAAAGTCGCTATCA
ATGAGCAATTGGCGCGACTGGCAGAGGCACTGAAGCAGGTGGGGCTAGAAAGCCAACGCCTGAAAATGCCCGCCCAACTC
TCCGGCGGCCAGCAGCAGCGCGTGGCACTGGCCCGAGCGATGATCACCCGCCCAGACGTGATCCTGTTTGATGAACCGCT
CTCTAATCTTGATGCTAAACTGCGCGAAAGCGTGCGTTTTGAGATTAAAGAACTGCAACGTCAGTACCATCTCACCTCTA
TTTACGTCACCCATGATCAGGCAGAAGCGCTGGCGATGTCGGACAAAATCGTGGTACTCAACGCAGGTAATGTGGAGCAA
ATCGGGGCACCTGAGGAGATTTACTACCGCCCGACCAGCCGCTTTGTGGCGGATTTCATCGGCGCGGCCAATATCGACAC
AGCTCATATTACTGCTGCAGAGCAACCCGGCTCTTGGCGAGTACGCTGCGCCATGGGCGAATTTTACGTCCATTCAACCA
CTCCGCCGCGTGCAGAGCACTGCTATATCTGCTGGCGGCCGGAAGATGTGCAATTTGTCGGCCCTCATCAGAGCGGCGAC
AACCACTTTACCCTGACACTCGAAAAAATGGCGTTTATGGGCAATCTCACTGAGGCCTGGGGCCATAATGATGCGGGGCT
GTCGGTACGTCTGCAACTGATTAAAAAACCTCCGGTGGTACTTGGCGGGCGGGCGTGTTTCCGCCTGCCGGAGAACGCTA
TTCACTTTTTGGAGCCGGTATCATGA

Upstream 100 bases:

>100_bases
CGTTTTTCCCTGTAGAACACCTGCCTTCGGTACTTCGGCGCAAAAACTATATGATATTTACAGTTCCATCGGGTGTGCGC
TAAGCTCTTTTCATCCCTCA

Downstream 100 bases:

>100_bases
AAAGCTGGCGCAACGACCTGCTTGCCTGGTCGCTGATGTTGAGTGGCCTGGGCACCATTCTGTTATTGATGGGTTCCACC
TTTTATGTCGTGGTGGTGCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MGPPFDFLLNICSCQTANCFNKSKGVFITDPKLKALLNPQPSWGFSGHKKVAINEQLARLAEALKQVGLESQRLKMPAQL
SGGQQQRVALARAMITRPDVILFDEPLSNLDAKLRESVRFEIKELQRQYHLTSIYVTHDQAEALAMSDKIVVLNAGNVEQ
IGAPEEIYYRPTSRFVADFIGAANIDTAHITAAEQPGSWRVRCAMGEFYVHSTTPPRAEHCYICWRPEDVQFVGPHQSGD
NHFTLTLEKMAFMGNLTEAWGHNDAGLSVRLQLIKKPPVVLGGRACFRLPENAIHFLEPVS

Sequences:

>Translated_301_residues
MGPPFDFLLNICSCQTANCFNKSKGVFITDPKLKALLNPQPSWGFSGHKKVAINEQLARLAEALKQVGLESQRLKMPAQL
SGGQQQRVALARAMITRPDVILFDEPLSNLDAKLRESVRFEIKELQRQYHLTSIYVTHDQAEALAMSDKIVVLNAGNVEQ
IGAPEEIYYRPTSRFVADFIGAANIDTAHITAAEQPGSWRVRCAMGEFYVHSTTPPRAEHCYICWRPEDVQFVGPHQSGD
NHFTLTLEKMAFMGNLTEAWGHNDAGLSVRLQLIKKPPVVLGGRACFRLPENAIHFLEPVS
>Mature_300_residues
GPPFDFLLNICSCQTANCFNKSKGVFITDPKLKALLNPQPSWGFSGHKKVAINEQLARLAEALKQVGLESQRLKMPAQLS
GGQQQRVALARAMITRPDVILFDEPLSNLDAKLRESVRFEIKELQRQYHLTSIYVTHDQAEALAMSDKIVVLNAGNVEQI
GAPEEIYYRPTSRFVADFIGAANIDTAHITAAEQPGSWRVRCAMGEFYVHSTTPPRAEHCYICWRPEDVQFVGPHQSGDN
HFTLTLEKMAFMGNLTEAWGHNDAGLSVRLQLIKKPPVVLGGRACFRLPENAIHFLEPVS

Specific function: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system [H]

COG id: COG3842

COG function: function code E; ABC-type spermidine/putrescine transport systems, ATPase components

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI42490749, Length=122, Percent_Identity=34.4262295081967, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87081709, Length=128, Percent_Identity=58.59375, Blast_Score=160, Evalue=8e-41,
Organism=Escherichia coli, GI1787370, Length=188, Percent_Identity=45.2127659574468, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI87082267, Length=266, Percent_Identity=37.218045112782, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1790467, Length=156, Percent_Identity=46.7948717948718, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1787712, Length=137, Percent_Identity=48.9051094890511, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI87081791, Length=211, Percent_Identity=34.1232227488152, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788761, Length=127, Percent_Identity=44.0944881889764, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1789032, Length=141, Percent_Identity=37.5886524822695, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788450, Length=128, Percent_Identity=40.625, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1788225, Length=131, Percent_Identity=38.9312977099237, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1787164, Length=92, Percent_Identity=47.8260869565217, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1787500, Length=159, Percent_Identity=31.4465408805031, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1787029, Length=126, Percent_Identity=37.3015873015873, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788644, Length=126, Percent_Identity=38.0952380952381, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789672, Length=152, Percent_Identity=34.8684210526316, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788506, Length=120, Percent_Identity=30.8333333333333, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787758, Length=158, Percent_Identity=32.2784810126582, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI48994883, Length=191, Percent_Identity=26.7015706806283, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789891, Length=106, Percent_Identity=41.5094339622642, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789962, Length=154, Percent_Identity=29.8701298701299, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786872, Length=118, Percent_Identity=36.4406779661017, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI145693107, Length=138, Percent_Identity=30.4347826086957, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786398, Length=122, Percent_Identity=33.6065573770492, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789864, Length=144, Percent_Identity=31.25, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786563, Length=136, Percent_Identity=35.2941176470588, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789963, Length=173, Percent_Identity=29.4797687861272, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786703, Length=76, Percent_Identity=50, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787547, Length=130, Percent_Identity=33.8461538461538, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787089, Length=109, Percent_Identity=35.7798165137615, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87081834, Length=120, Percent_Identity=38.3333333333333, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787105, Length=104, Percent_Identity=41.3461538461538, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789873, Length=100, Percent_Identity=39, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786253, Length=104, Percent_Identity=32.6923076923077, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790162, Length=101, Percent_Identity=34.6534653465347, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790544, Length=152, Percent_Identity=30.9210526315789, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788053, Length=78, Percent_Identity=43.5897435897436, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI48994997, Length=109, Percent_Identity=29.3577981651376, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1790190, Length=82, Percent_Identity=40.2439024390244, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534520, Length=118, Percent_Identity=33.8983050847458, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193209708, Length=100, Percent_Identity=40, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17511077, Length=86, Percent_Identity=44.1860465116279, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=98, Percent_Identity=33.6734693877551, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324985, Length=94, Percent_Identity=32.9787234042553, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR008995
- InterPro:   IPR017879
- InterPro:   IPR005893
- InterPro:   IPR013611 [H]

Pfam domain/function: PF00005 ABC_tran; PF08402 TOBE_2 [H]

EC number: =3.6.3.31 [H]

Molecular weight: Translated: 33581; Mature: 33450

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPPFDFLLNICSCQTANCFNKSKGVFITDPKLKALLNPQPSWGFSGHKKVAINEQLARL
CCCCHHHHHHHHCCCCCCCCCCCCCEEEECCHHHHHCCCCCCCCCCCCEEEEHHHHHHHH
AEALKQVGLESQRLKMPAQLSGGQQQRVALARAMITRPDVILFDEPLSNLDAKLRESVRF
HHHHHHHCCCHHHHCCCHHCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHH
EIKELQRQYHLTSIYVTHDQAEALAMSDKIVVLNAGNVEQIGAPEEIYYRPTSRFVADFI
HHHHHHHHHEEEEEEEECCCCHHEEECCCEEEEECCCHHHCCCCHHEEECCHHHHHHHHH
GAANIDTAHITAAEQPGSWRVRCAMGEFYVHSTTPPRAEHCYICWRPEDVQFVGPHQSGD
CCCCCCCEEEEECCCCCCEEEEEEECEEEEECCCCCCCCEEEEEECCCCCEEECCCCCCC
NHFTLTLEKMAFMGNLTEAWGHNDAGLSVRLQLIKKPPVVLGGRACFRLPENAIHFLEPV
CEEEEEEEHHHHHCCCHHHCCCCCCCCEEEEEEECCCCEEECCHHHEECCHHHHHHCCCC
S
C
>Mature Secondary Structure 
GPPFDFLLNICSCQTANCFNKSKGVFITDPKLKALLNPQPSWGFSGHKKVAINEQLARL
CCCHHHHHHHHCCCCCCCCCCCCCEEEECCHHHHHCCCCCCCCCCCCEEEEHHHHHHHH
AEALKQVGLESQRLKMPAQLSGGQQQRVALARAMITRPDVILFDEPLSNLDAKLRESVRF
HHHHHHHCCCHHHHCCCHHCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHH
EIKELQRQYHLTSIYVTHDQAEALAMSDKIVVLNAGNVEQIGAPEEIYYRPTSRFVADFI
HHHHHHHHHEEEEEEEECCCCHHEEECCCEEEEECCCHHHCCCCHHEEECCHHHHHHHHH
GAANIDTAHITAAEQPGSWRVRCAMGEFYVHSTTPPRAEHCYICWRPEDVQFVGPHQSGD
CCCCCCCEEEEECCCCCCEEEEEEECEEEEECCCCCCCCEEEEEECCCCCEEECCCCCCC
NHFTLTLEKMAFMGNLTEAWGHNDAGLSVRLQLIKKPPVVLGGRACFRLPENAIHFLEPV
CEEEEEEEHHHHHCCCHHHCCCCCCCCEEEEEEECCCCEEECCHHHEECCHHHHHHCCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]