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The map label for this gene is pssA [H]

Identifier: 108810988

GI number: 108810988

Start: 959354

End: 960709

Strand: Reverse

Name: pssA [H]

Synonym: YPN_0823

Alternate gene names: 108810988

Gene position: 960709-959354 (Counterclockwise)

Preceding gene: 108810989

Following gene: 108810987

Centisome position: 21.19

GC content: 46.53

Gene sequence:

>1356_bases
ATGTTGTCAAAATTCAAACGTAGCAAACATCAACAACACCTTGCACAACTGCCCAAACTCCCCCAGTCAGTTGATGATGT
CCAAACGCTTTATTGCCCCAAGGTTTTCCGCTCTACTCTGTTGGAACTCATCGCTCAGGCAACCAAACGTATTTTTCTGG
TGGCACTTTATCTGGAGCAGGATGACGCAGGCCGTGATGTAATGAATGCCCTCTATCAGGCCAAGCAGTCGCATCCTGAA
CTGGAGATCTATGTACTGGTAGATTGGCACCGGGCTCAGCGTGGCCGTATTGGTGCGGCAGCCGTCAATACTAATGCCGA
TTGGTATTGCGATATGGCGGCTAAACATCCAAATATTTCTGTTCCTGTTTACGGTGTCCCGGTCAATACGCGTGAAGCAT
TGGGTGTACTGCACCTAAAAGGCTTTATCATTGACGACACCGTTATTTATAGCGGTGCCAGCATCAATGATGTCTATCTC
TATCAGAATGATAAATATCGTTATGATCGCTACCAGCTAATCACTAATCCGTCACTCGCTACCATTATGGTTGATTACGT
GAAACAACGGATACTGAGTGCCGGAGCAGTTCAACGCCTTGACCGTAATGACCGACCTACCACCCCCGAGATCAAGAATG
AGACCCGCCAGTTTCGCTCATCACTGCGTGATGCCAGTTACCAATTCTCGGCACAAGCGCATAACGATGAGTTAGCGGTC
ACTCCTCTGGTTGGGTTAGGTAAGAAGAGTTTACTAAACAAAACGATTCATCACTTAATGGCCTCCGCTGATGAACGCCT
GACCATTTGCACCCCCTACTTTAACCTGCCCGCGCTGTTAGTCCGTAATATTATTTATCTGCTGCGGGAAGGTAAGCAGG
TTGAGATTATCGTTGGTGATAAAACCGCAAATGACTTTTATATCCCTGAAGATCAACCCTTTAAAATTATCGGTGCACTG
CCGTATTTATACGAAATCAACCTGCGTCGTTTCCTGAGCCGCTTACAACCGTATGTTGATAACGGGCAGCTCATTGTTCG
CTTATGGAAAGATGGCGACAACACCTATCATTTGAAAGGGATGTGGGTAGATAACAATTGGCAGTTGATCACGGGCAATA
ACCTAAACCCGCGCGCATGGCGCTTGGATTTGGAGAATGCCATTTTGATCCACGATCCTAAGCATGAAATGCATGAACAG
CGGGCCAAAGAACTGGAGTGTATCCGCACTCATACCAAAGTGGTTTCACACTACCTTGAACTGGAGAATATCCAACAATA
TCCGGTTAAAGTTCGCAAACTTATCCGCCGTTTGCGCAGGATCCGCATTGATCGGTTAATTAGCCGTATTCTATAA

Upstream 100 bases:

>100_bases
CAATCCAGAAAAGTAATGGTATTATCGCCGACTCTATGGATTAGTGTTTTTTTGATATGGCGGTTTTGCCATTAAATAAC
AAGAGAAGAAGCGCACTGTG

Downstream 100 bases:

>100_bases
GTCTTAAAGATAAAACCCGGTGAATTAGCGGGTTTTCATCTCCCACTAAAAGAGAAACTCTATGCGGCTGCATATCTATC
TTCGCCGATTGCTTATCGCC

Product: phosphatidylserine synthase

Products: NA

Alternate protein names: Phosphatidylserine synthase [H]

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MLSKFKRSKHQQHLAQLPKLPQSVDDVQTLYCPKVFRSTLLELIAQATKRIFLVALYLEQDDAGRDVMNALYQAKQSHPE
LEIYVLVDWHRAQRGRIGAAAVNTNADWYCDMAAKHPNISVPVYGVPVNTREALGVLHLKGFIIDDTVIYSGASINDVYL
YQNDKYRYDRYQLITNPSLATIMVDYVKQRILSAGAVQRLDRNDRPTTPEIKNETRQFRSSLRDASYQFSAQAHNDELAV
TPLVGLGKKSLLNKTIHHLMASADERLTICTPYFNLPALLVRNIIYLLREGKQVEIIVGDKTANDFYIPEDQPFKIIGAL
PYLYEINLRRFLSRLQPYVDNGQLIVRLWKDGDNTYHLKGMWVDNNWQLITGNNLNPRAWRLDLENAILIHDPKHEMHEQ
RAKELECIRTHTKVVSHYLELENIQQYPVKVRKLIRRLRRIRIDRLISRIL

Sequences:

>Translated_451_residues
MLSKFKRSKHQQHLAQLPKLPQSVDDVQTLYCPKVFRSTLLELIAQATKRIFLVALYLEQDDAGRDVMNALYQAKQSHPE
LEIYVLVDWHRAQRGRIGAAAVNTNADWYCDMAAKHPNISVPVYGVPVNTREALGVLHLKGFIIDDTVIYSGASINDVYL
YQNDKYRYDRYQLITNPSLATIMVDYVKQRILSAGAVQRLDRNDRPTTPEIKNETRQFRSSLRDASYQFSAQAHNDELAV
TPLVGLGKKSLLNKTIHHLMASADERLTICTPYFNLPALLVRNIIYLLREGKQVEIIVGDKTANDFYIPEDQPFKIIGAL
PYLYEINLRRFLSRLQPYVDNGQLIVRLWKDGDNTYHLKGMWVDNNWQLITGNNLNPRAWRLDLENAILIHDPKHEMHEQ
RAKELECIRTHTKVVSHYLELENIQQYPVKVRKLIRRLRRIRIDRLISRIL
>Mature_451_residues
MLSKFKRSKHQQHLAQLPKLPQSVDDVQTLYCPKVFRSTLLELIAQATKRIFLVALYLEQDDAGRDVMNALYQAKQSHPE
LEIYVLVDWHRAQRGRIGAAAVNTNADWYCDMAAKHPNISVPVYGVPVNTREALGVLHLKGFIIDDTVIYSGASINDVYL
YQNDKYRYDRYQLITNPSLATIMVDYVKQRILSAGAVQRLDRNDRPTTPEIKNETRQFRSSLRDASYQFSAQAHNDELAV
TPLVGLGKKSLLNKTIHHLMASADERLTICTPYFNLPALLVRNIIYLLREGKQVEIIVGDKTANDFYIPEDQPFKIIGAL
PYLYEINLRRFLSRLQPYVDNGQLIVRLWKDGDNTYHLKGMWVDNNWQLITGNNLNPRAWRLDLENAILIHDPKHEMHEQ
RAKELECIRTHTKVVSHYLELENIQQYPVKVRKLIRRLRRIRIDRLISRIL

Specific function: Unknown

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI87082134, Length=431, Percent_Identity=73.0858468677494, Blast_Score=664, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25143331, Length=409, Percent_Identity=24.2053789731051, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28572961, Length=409, Percent_Identity=24.4498777506112, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016270
- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: =2.7.8.8 [H]

Molecular weight: Translated: 52389; Mature: 52389

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSKFKRSKHQQHLAQLPKLPQSVDDVQTLYCPKVFRSTLLELIAQATKRIFLVALYLEQ
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEC
DDAGRDVMNALYQAKQSHPELEIYVLVDWHRAQRGRIGAAAVNTNADWYCDMAAKHPNIS
CCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEEEEECCCCCEEEEECCCCCCCC
VPVYGVPVNTREALGVLHLKGFIIDDTVIYSGASINDVYLYQNDKYRYDRYQLITNPSLA
EEEEECCCCCHHHHHHHEEECEEEECEEEECCCCCCEEEEEECCCEEECEEEEEECCCHH
TIMVDYVKQRILSAGAVQRLDRNDRPTTPEIKNETRQFRSSLRDASYQFSAQAHNDELAV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEE
TPLVGLGKKSLLNKTIHHLMASADERLTICTPYFNLPALLVRNIIYLLREGKQVEIIVGD
ECCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECC
KTANDFYIPEDQPFKIIGALPYLYEINLRRFLSRLQPYVDNGQLIVRLWKDGDNTYHLKG
CCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEEE
MWVDNNWQLITGNNLNPRAWRLDLENAILIHDPKHEMHEQRAKELECIRTHTKVVSHYLE
EEECCCEEEEECCCCCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LENIQQYPVKVRKLIRRLRRIRIDRLISRIL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLSKFKRSKHQQHLAQLPKLPQSVDDVQTLYCPKVFRSTLLELIAQATKRIFLVALYLEQ
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEC
DDAGRDVMNALYQAKQSHPELEIYVLVDWHRAQRGRIGAAAVNTNADWYCDMAAKHPNIS
CCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEEEEECCCCCEEEEECCCCCCCC
VPVYGVPVNTREALGVLHLKGFIIDDTVIYSGASINDVYLYQNDKYRYDRYQLITNPSLA
EEEEECCCCCHHHHHHHEEECEEEECEEEECCCCCCEEEEEECCCEEECEEEEEECCCHH
TIMVDYVKQRILSAGAVQRLDRNDRPTTPEIKNETRQFRSSLRDASYQFSAQAHNDELAV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEE
TPLVGLGKKSLLNKTIHHLMASADERLTICTPYFNLPALLVRNIIYLLREGKQVEIIVGD
ECCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECC
KTANDFYIPEDQPFKIIGALPYLYEINLRRFLSRLQPYVDNGQLIVRLWKDGDNTYHLKG
CCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEEE
MWVDNNWQLITGNNLNPRAWRLDLENAILIHDPKHEMHEQRAKELECIRTHTKVVSHYLE
EEECCCEEEEECCCCCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LENIQQYPVKVRKLIRRLRRIRIDRLISRIL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2002065; 9205837; 9278503; 1323044 [H]