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The map label for this gene is asd [H]

Identifier: 108801851

GI number: 108801851

Start: 5176677

End: 5177711

Strand: Reverse

Name: asd [H]

Synonym: Mmcs_4888

Alternate gene names: 108801851

Gene position: 5177711-5176677 (Counterclockwise)

Preceding gene: 108801852

Following gene: 108801850

Centisome position: 90.75

GC content: 68.89

Gene sequence:

>1035_bases
ATGGTCAACATCGGAGTGGTCGGCGCGACCGGCCAGGTCGGCCAGGTCATGCGCACCCTGCTCGAGGAGCGCGATTTCCC
GGCCACCAGCGTCAGGTTCTTCGCCTCGGCCCGCTCGCAGGGTCGGAAGCTGCCGTTCCGCGGTCAGGAGATCGAGGTCG
AGGACGCCGGGACCGCCGACCCGTCGGGTCTGGACATCGCGCTGTTCTCGGCGGGCGCGACCATGTCGCGGGTGCAGGCG
CCACGGTTCGCCGCCGCCGGCGCCGTCGTGGTCGACAACTCGTCGGCCTGGCGTAAGGACCCCGACGTACCGCTGGTGGT
CAGCGAGGTGAACTTCGAGCGCGATGCCGGTACTCGCCCGAAAGGCATCATCGCCAATCCGAACTGCACGACGATGGCCG
CGATGCCGGTGCTCAAGCCGCTGCACGACGAGGCCGGTCTGGTGCGCATGATCGCGTCGACGTATCAGGCCGTCTCGGGC
AGCGGTCTGGCCGGTGTCGAGGAACTGTTCGGTCAGGCCAGCGCCGTCGTCTCGGGCAGCCGCGACCTGGTGCACGACGG
CGGCGCAGTCGACTTCCCGGCGCCGAACAAATACGTCGCGCCGATCGCGTTCAACGTGGTGCCGCTGGCCGGATCGCTGG
TCGACGACGGTTCGGGGGAGACCGACGAGGACCAGAAGCTGCGCAACGAGAGCCGCAAGATCCTCGGCATCCCGGAGTTG
CTGGTGAGCGGGACGTGCGTGCGGGTGCCGGTCTACACGGGCCATTCGCTGTCCATCAATGCCGAATTCGCCCAACCGCT
TTCGGTCGATCGCGCGAAGGAACTGCTGGCCGCTGCGCCGGGGGTCAAGCTGGTCGACGTGCCGACGCCGCTGGCCGCCG
CGGGGATCGACGAATCGCTGGTTGGCCGCATCCGCCAGGATCCAGGCGCGCCGGAGGGGCGCGGGCTTGCGCTGTTCATC
TCCGGCGACAACCTGCGAAAAGGCGCGGCGCTGAACACCATTCAGATCGCCGAGTTGCTGGCCGCCCAGCTCTGA

Upstream 100 bases:

>100_bases
CACGGAATTGGACAAGGCGGTCGCCGCGTTGCACGAGGCGTTCGGCCTCGGCGGCGACGAAGAGGCCGTGGTGTACGCAG
GGACGGGACGGTAATTCCGG

Downstream 100 bases:

>100_bases
CCGACCGGTGTACCGGGGCCGCGTGATCGCCGCCGCGGTGCTGGCTGCCGCGTTGTGTGTACCCGCGGCGCAGGCTCAAC
CACCGACACCGGTGCCCGGT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MVNIGVVGATGQVGQVMRTLLEERDFPATSVRFFASARSQGRKLPFRGQEIEVEDAGTADPSGLDIALFSAGATMSRVQA
PRFAAAGAVVVDNSSAWRKDPDVPLVVSEVNFERDAGTRPKGIIANPNCTTMAAMPVLKPLHDEAGLVRMIASTYQAVSG
SGLAGVEELFGQASAVVSGSRDLVHDGGAVDFPAPNKYVAPIAFNVVPLAGSLVDDGSGETDEDQKLRNESRKILGIPEL
LVSGTCVRVPVYTGHSLSINAEFAQPLSVDRAKELLAAAPGVKLVDVPTPLAAAGIDESLVGRIRQDPGAPEGRGLALFI
SGDNLRKGAALNTIQIAELLAAQL

Sequences:

>Translated_344_residues
MVNIGVVGATGQVGQVMRTLLEERDFPATSVRFFASARSQGRKLPFRGQEIEVEDAGTADPSGLDIALFSAGATMSRVQA
PRFAAAGAVVVDNSSAWRKDPDVPLVVSEVNFERDAGTRPKGIIANPNCTTMAAMPVLKPLHDEAGLVRMIASTYQAVSG
SGLAGVEELFGQASAVVSGSRDLVHDGGAVDFPAPNKYVAPIAFNVVPLAGSLVDDGSGETDEDQKLRNESRKILGIPEL
LVSGTCVRVPVYTGHSLSINAEFAQPLSVDRAKELLAAAPGVKLVDVPTPLAAAGIDESLVGRIRQDPGAPEGRGLALFI
SGDNLRKGAALNTIQIAELLAAQL
>Mature_344_residues
MVNIGVVGATGQVGQVMRTLLEERDFPATSVRFFASARSQGRKLPFRGQEIEVEDAGTADPSGLDIALFSAGATMSRVQA
PRFAAAGAVVVDNSSAWRKDPDVPLVVSEVNFERDAGTRPKGIIANPNCTTMAAMPVLKPLHDEAGLVRMIASTYQAVSG
SGLAGVEELFGQASAVVSGSRDLVHDGGAVDFPAPNKYVAPIAFNVVPLAGSLVDDGSGETDEDQKLRNESRKILGIPEL
LVSGTCVRVPVYTGHSLSINAEFAQPLSVDRAKELLAAAPGVKLVDVPTPLAAAGIDESLVGRIRQDPGAPEGRGLALFI
SGDNLRKGAALNTIQIAELLAAQL

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=345, Percent_Identity=31.8840579710145, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI1789841, Length=361, Percent_Identity=27.9778393351801, Blast_Score=96, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6320362, Length=391, Percent_Identity=27.8772378516624, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 35828; Mature: 35828

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNIGVVGATGQVGQVMRTLLEERDFPATSVRFFASARSQGRKLPFRGQEIEVEDAGTAD
CEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCC
PSGLDIALFSAGATMSRVQAPRFAAAGAVVVDNSSAWRKDPDVPLVVSEVNFERDAGTRP
CCCCEEEEEECCCHHHHHCCCCHHHCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCC
KGIIANPNCTTMAAMPVLKPLHDEAGLVRMIASTYQAVSGSGLAGVEELFGQASAVVSGS
CCEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHEECCC
RDLVHDGGAVDFPAPNKYVAPIAFNVVPLAGSLVDDGSGETDEDQKLRNESRKILGIPEL
CCEEECCCEECCCCCCCEECEEEEEEEECCCCEECCCCCCCCHHHHHHHHCCEEECCHHH
LVSGTCVRVPVYTGHSLSINAEFAQPLSVDRAKELLAAAPGVKLVDVPTPLAAAGIDESL
HHCCCEEEEEEEECCEEEEEHHCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHCCCHHH
VGRIRQDPGAPEGRGLALFISGDNLRKGAALNTIQIAELLAAQL
HHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MVNIGVVGATGQVGQVMRTLLEERDFPATSVRFFASARSQGRKLPFRGQEIEVEDAGTAD
CEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCC
PSGLDIALFSAGATMSRVQAPRFAAAGAVVVDNSSAWRKDPDVPLVVSEVNFERDAGTRP
CCCCEEEEEECCCHHHHHCCCCHHHCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCC
KGIIANPNCTTMAAMPVLKPLHDEAGLVRMIASTYQAVSGSGLAGVEELFGQASAVVSGS
CCEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHEECCC
RDLVHDGGAVDFPAPNKYVAPIAFNVVPLAGSLVDDGSGETDEDQKLRNESRKILGIPEL
CCEEECCCEECCCCCCCEECEEEEEEEECCCCEECCCCCCCCHHHHHHHHCCEEECCHHH
LVSGTCVRVPVYTGHSLSINAEFAQPLSVDRAKELLAAAPGVKLVDVPTPLAAAGIDESL
HHCCCEEEEEEEECCEEEEEHHCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHCCCHHH
VGRIRQDPGAPEGRGLALFISGDNLRKGAALNTIQIAELLAAQL
HHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7910936; 12788972 [H]