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The map label for this gene is 108801845

Identifier: 108801845

GI number: 108801845

Start: 5171965

End: 5173239

Strand: Reverse

Name: 108801845

Synonym: Mmcs_4882

Alternate gene names: NA

Gene position: 5173239-5171965 (Counterclockwise)

Preceding gene: 108801846

Following gene: 108801844

Centisome position: 90.67

GC content: 73.1

Gene sequence:

>1275_bases
ATGACCGTTCCGACGACCTACGACCCGGGGTGCGATACGGCACCCGACGAATTCGCCTCGGCGGCCGACGCCGCCGAACA
CATCACCGAACACTGTCTGCACGACGGGCCGGTCGGCCAGGTCGGCCTCGAGGTCGAGGCGCATTCGTTCGATCTGGCGG
ACCCACGCCGTCGCCCCGACTGGGGTGAGGTGACGGATGCGATCGCCGGTGTCGGGGCACTGCCCGGGGGCAGCAGGATC
ACCGTCGAACCCGGTGGCGCGGTGGAACTGTCCGGCCCGCCCGCGGACGGATCGGTGGCCGCGATCGCCGCGATGACCTC
CGACCGGGCCGTGCTGCGCACGGCCTTCGCGCAGCGCGGGCTCGGGCTGGTGCTCGTGGGCGCCGACCCGCTGCGCCGGC
CGCGCCGCGTCAACCCCGGCGGCCGGTACTCCGCGATGGAGGCCTTCTTCACCGCGAGCGGTACCGGCGCGGCGGGTGCG
TTCATGATGACCTCGACCGCGTCGATCCAGCTCAACCTCGACGCCGGACCCCGGCGCGGCTGGGCCGACCGGGTCCGGCT
GGCACATGCGCTCGGCCCGACGATGATCGCCGCCACGGCCAACTCCCCGCTGCTCGCCGGCCGGTTCTCGGGGTGGCAGA
GCAGCAGGCAGTGGGTCTGGGGTGAGCTCGACGAAGCCCGCTGCGGGCCGGTGCTCGGCGCCAGCGGGGACGACCCGGCC
AGCGACTGGGCCCGCTACGCGCTGCGCGCCCCGGTGATGCTGGTGCACAATCCCGAGCCGGTGCCGGTCACGGACTGGGT
GCCGTTCGCCGAGTGGGCCGACGGACAGACCCTCCTCGGCGGCCGGCGTCCGACACGGTCGGACCTCGAATACCACCTGA
CCACCCTCTTCCCGCCGGTGCGCCCGCGCCGCTGGCTCGAAATCCGTTATCTGGACGCGGTTTCCGACGCCCTGTGGCCG
GCCGTCGCCTTCACGCTGACCACCCTGCTCGACGATCCGGCGGCCGCCGACATCGCCGCGGAGGCCACCGAGTCGGTGGC
CACGGCCTGGGACCGGGCCGCGCGTATCGGGCTCGGCGACCGCCGACTGCACGCCGCGGCGCTGCGCTGCGTCGAGACCG
CCGCCGAGCGGGCACCCGCAGCCGTGATGGAATCGATGCAGCAGTTGGTGCGTTCGGTCGAAGAAGGCAGATCACCGGCC
GACGACTTCGCCGACCGCGCGGTCGCCTACGGGATCGGACCAGCCGTACGCCAACTCGCGAAAGGTGAGTCTTGA

Upstream 100 bases:

>100_bases
CGCTCTGGACAATGAGGACGGTAGCGGTGATCGGCCGATCCCGCGGCTGCCAACCAGCGGTCCAGTCCCAGCGTCCGGAC
CCGGGGAGGGATGGGTTCAG

Downstream 100 bases:

>100_bases
CTGCACGTGACACCCTGGCCGACGAACTGGGCAGAGCACGCGACCGCACGCTCCGGCTGGTCGACTTCGACGACATGGAG
TTGCGGCGGCAGTACGACCC

Product: glutamate--cysteine ligase, GCS2

Products: NA

Alternate protein names: Glutamate/Cysteine Ligase; Glutamate/Cysteine Ligase Family Protein; Gamma-Glutamylcysteine Synthetase; Glutamylcysteine Synthetase; Glutamate-Cysteine Ligase Family 2 Protein; Glutamate-Cysteine Ligase GSHA; Glutamate-Cysteine Ligase GshA; Glutamate-Cysteine Ligase Protein; Glutathione Synthetase; Glutamate-Cysteine Ligase Gsha; Glutamate-Cysteine Ligase Protein; Glutamate-Cysteine Ligase Family Protein; Glutamate Cystein Ligase Protein

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MTVPTTYDPGCDTAPDEFASAADAAEHITEHCLHDGPVGQVGLEVEAHSFDLADPRRRPDWGEVTDAIAGVGALPGGSRI
TVEPGGAVELSGPPADGSVAAIAAMTSDRAVLRTAFAQRGLGLVLVGADPLRRPRRVNPGGRYSAMEAFFTASGTGAAGA
FMMTSTASIQLNLDAGPRRGWADRVRLAHALGPTMIAATANSPLLAGRFSGWQSSRQWVWGELDEARCGPVLGASGDDPA
SDWARYALRAPVMLVHNPEPVPVTDWVPFAEWADGQTLLGGRRPTRSDLEYHLTTLFPPVRPRRWLEIRYLDAVSDALWP
AVAFTLTTLLDDPAAADIAAEATESVATAWDRAARIGLGDRRLHAAALRCVETAAERAPAAVMESMQQLVRSVEEGRSPA
DDFADRAVAYGIGPAVRQLAKGES

Sequences:

>Translated_424_residues
MTVPTTYDPGCDTAPDEFASAADAAEHITEHCLHDGPVGQVGLEVEAHSFDLADPRRRPDWGEVTDAIAGVGALPGGSRI
TVEPGGAVELSGPPADGSVAAIAAMTSDRAVLRTAFAQRGLGLVLVGADPLRRPRRVNPGGRYSAMEAFFTASGTGAAGA
FMMTSTASIQLNLDAGPRRGWADRVRLAHALGPTMIAATANSPLLAGRFSGWQSSRQWVWGELDEARCGPVLGASGDDPA
SDWARYALRAPVMLVHNPEPVPVTDWVPFAEWADGQTLLGGRRPTRSDLEYHLTTLFPPVRPRRWLEIRYLDAVSDALWP
AVAFTLTTLLDDPAAADIAAEATESVATAWDRAARIGLGDRRLHAAALRCVETAAERAPAAVMESMQQLVRSVEEGRSPA
DDFADRAVAYGIGPAVRQLAKGES
>Mature_423_residues
TVPTTYDPGCDTAPDEFASAADAAEHITEHCLHDGPVGQVGLEVEAHSFDLADPRRRPDWGEVTDAIAGVGALPGGSRIT
VEPGGAVELSGPPADGSVAAIAAMTSDRAVLRTAFAQRGLGLVLVGADPLRRPRRVNPGGRYSAMEAFFTASGTGAAGAF
MMTSTASIQLNLDAGPRRGWADRVRLAHALGPTMIAATANSPLLAGRFSGWQSSRQWVWGELDEARCGPVLGASGDDPAS
DWARYALRAPVMLVHNPEPVPVTDWVPFAEWADGQTLLGGRRPTRSDLEYHLTTLFPPVRPRRWLEIRYLDAVSDALWPA
VAFTLTTLLDDPAAADIAAEATESVATAWDRAARIGLGDRRLHAAALRCVETAAERAPAAVMESMQQLVRSVEEGRSPAD
DFADRAVAYGIGPAVRQLAKGES

Specific function: Unknown

COG id: COG3572

COG function: function code H; Gamma-glutamylcysteine synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 44926; Mature: 44795

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVPTTYDPGCDTAPDEFASAADAAEHITEHCLHDGPVGQVGLEVEAHSFDLADPRRRPD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCC
WGEVTDAIAGVGALPGGSRITVEPGGAVELSGPPADGSVAAIAAMTSDRAVLRTAFAQRG
HHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHCC
LGLVLVGADPLRRPRRVNPGGRYSAMEAFFTASGTGAAGAFMMTSTASIQLNLDAGPRRG
CCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEECEEEEEEECCCCCCC
WADRVRLAHALGPTMIAATANSPLLAGRFSGWQSSRQWVWGELDEARCGPVLGASGDDPA
HHHHHHHHHHCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
SDWARYALRAPVMLVHNPEPVPVTDWVPFAEWADGQTLLGGRRPTRSDLEYHLTTLFPPV
HHHHHHHHHCCEEEEECCCCCCCCCCCCCHHCCCCCEEECCCCCCCCHHHHHHHHHCCCC
RPRRWLEIRYLDAVSDALWPAVAFTLTTLLDDPAAADIAAEATESVATAWDRAARIGLGD
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
RRLHAAALRCVETAAERAPAAVMESMQQLVRSVEEGRSPADDFADRAVAYGIGPAVRQLA
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHH
KGES
CCCC
>Mature Secondary Structure 
TVPTTYDPGCDTAPDEFASAADAAEHITEHCLHDGPVGQVGLEVEAHSFDLADPRRRPD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCC
WGEVTDAIAGVGALPGGSRITVEPGGAVELSGPPADGSVAAIAAMTSDRAVLRTAFAQRG
HHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHCC
LGLVLVGADPLRRPRRVNPGGRYSAMEAFFTASGTGAAGAFMMTSTASIQLNLDAGPRRG
CCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEECEEEEEEECCCCCCC
WADRVRLAHALGPTMIAATANSPLLAGRFSGWQSSRQWVWGELDEARCGPVLGASGDDPA
HHHHHHHHHHCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
SDWARYALRAPVMLVHNPEPVPVTDWVPFAEWADGQTLLGGRRPTRSDLEYHLTTLFPPV
HHHHHHHHHCCEEEEECCCCCCCCCCCCCHHCCCCCEEECCCCCCCCHHHHHHHHHCCCC
RPRRWLEIRYLDAVSDALWPAVAFTLTTLLDDPAAADIAAEATESVATAWDRAARIGLGD
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
RRLHAAALRCVETAAERAPAAVMESMQQLVRSVEEGRSPADDFADRAVAYGIGPAVRQLA
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHH
KGES
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA