Definition Mycobacterium sp. MCS chromosome, complete genome.
Accession NC_008146
Length 5,705,448

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The map label for this gene is ftsH [H]

Identifier: 108801733

GI number: 108801733

Start: 5045389

End: 5047740

Strand: Reverse

Name: ftsH [H]

Synonym: Mmcs_4770

Alternate gene names: 108801733

Gene position: 5047740-5045389 (Counterclockwise)

Preceding gene: 108801738

Following gene: 108801732

Centisome position: 88.47

GC content: 68.49

Gene sequence:

>2352_bases
ATGAACCGGAAAAATGTGATCCGCACGCTGATCGTGATCGCGGTCGTGTTGTTGCTGGGCTGGTCGTTCTTTTATTTCAG
TGACGACACCCGTGGATTCAAGCCCGTCGACACCTCGGTGGCGATCTCGCAGATCAACAGCGACAACGTCAAGAGCGCCC
AGATCGACGATCGTGAACAGCAGTTGCGGCTCGAACTGAAGAGCGGCAACGGCGAGACCGAGGACAGCGACAAGATCCTC
ACGAAGTATCCGACCGGGTACGCGGTCACGCTGTTCGAATCGCTGCAGGACAAGAACGTCAAGATCAACACGGTCGTCAA
CCAGGGCAGCGTGCTGGGGTCACTCCTCATCTACATGCTCCCGCTGCTGCTGTTGGTCGCGCTGTTCGTCTTCTTCTCCC
GGATGCAGACCGGCGGCCGGATGGGCTTCGGCTTCGGCAAGTCGCGGGCCAAGCAGCTCACCAAGGACATGCCCAAGACG
ACGTTCGCCGACGTCGCCGGCGCGGATGAGGCGGTCGAAGAGCTCTACGAGATCAAGGACTTCCTGCAGAACCCGTCGCG
CTATCAGGCGCTGGGCGCCAAGATCCCCAGGGGCGTGCTGCTCTACGGTCCGCCCGGCACGGGCAAGACCCTGCTCGCCC
GCGCCGTCGCAGGTGAAGCGGGTGTCCCGTTCTTCACGATCTCGGGTTCGGACTTCGTCGAGATGTTCGTCGGCGTCGGC
GCCTCGCGCGTGCGCGACCTGTTCGAACAGGCCAAGCAGAACAGCCCGTCGATCATCTTCGTCGACGAGATCGACGCGGT
CGGTCGCCAGCGCGGCGCCGGCCTCGGCGGCGGTCACGACGAACGCGAGCAGACGCTCAACCAGCTGCTGGTGGAGATGG
ACGGATTCGGCGACCGCCAGGGCGTCATCCTCATCGCGGCCACCAACCGGCCCGACATCCTCGACCCGGCGCTGCTGCGC
CCGGGCCGCTTCGACCGGCAGATCCCGGTCACCAGCCCCGACCTCGCCGGCCGCCGCGCCGTGCTCAAGGTTCACTCGCA
GGGCAAGCCGATGGCCGGTGACGCCGACCTCGACGGGCTGGCCAAGCGCACCGTCGGCATGTCCGGCGCCGACCTGGCCA
ACGTCATCAACGAGGCCGCGCTGCTCACTGCCCGCGAGAACGGCACCGTCATCACGGGTCTCGCGCTCGAGGAGGCCGTC
GACCGGGTGGTCGGCGGACCCCGCCGCAAGAGCCGCATCATCAGCGAGCACGAGAAGAAGATCACCGCCTACCACGAGGG
TGGCCACACGCTGGCCGCCTGGGCGATGCCCGACATCGAGCCCATCTACAAGGTGACGATCCTGGCCCGCGGCCGCACCG
GCGGCCACGCGGTCGCCGTCCCCGAGGACGACAAGGGTCTGATGACCCGCTCGGAGATGATCTCCCGGCTGGTGTTCGCC
ATGGGTGGCCGCGCCGCCGAGGAACTCGTGTTCCGCGAGCCGACCACCGGCGCGGTGTCCGACATCCAGCAGGCCACCAA
GATCGCGCGCGCGATGGTCACCGAGTACGGCATGAGCAGCAAGCTCGGCGCGGTGCGGTACGGCACCGAACACGGCGACC
CGTTCCTCGGCCGCACGATGGGCACTTCGTCGGACTACAGCCACGAGGTCGCGCAGATCATCGACGACGAGGTGCGCAAG
CTCATCGAGGCCGCCCACACCGAGGCGTGGGAGATCCTCACCGAGTACCGCGACATCCTCGACACCCTCGCCGGTGAGCT
CCTGGAGAAGGAGACCCTGCACCGCGTCGAACTCGAGGCGATCTTCGGCGACGTCAAGAAGCGCCCGCGCCTGACGATGT
TCGACGACTTCGGTGGCCGCGTGCCGTCGGACAAGCCGCCCATCAAGACTCCGGGCGAGCTGGCGATCGAGCGCGGTGAG
GAGTGGCCGCAGCCCAAGCCCGAACCCGCGTTCAAGGCGGCGATCGCGGCGGCCAGCAAGGCCGCCGAGGAAGCCGCCGC
CCGCAGCAACGGCGCGAACGGATCCAGCGGTGCCAACGGCTCCCCGAACGGGGCGCCCAACGGTGCGACGCAGCCCGACT
ACGGTGCGCCCGCAGGCTGGCATGCGCCGGGCTGGCCGCCGCAGCAGCAGCCGTCGGGCCAGCAGGGCGGCTACTGGTAT
CCGCCGCCCTCCCCGAATCCGGGCTGGGGCGAACCGCCGCGGCAGCAGCAGCCCTACCCGCCGTACCAGCAGCACTACCC
GCAGCCCGGTCACGGGCCGCAGGGTGCCAATCCGCCACGCGACCCGCAGCAGGAGCGGGGCCGCGACGGCGACCGTCCCG
GTGACCGTCCGAACCCGCCTGCGCAGCACTGA

Upstream 100 bases:

>100_bases
CGGGAACAACCGCACGTTGGTCTAGCGGTAGCCTGAACTAATCCCAGCTGCACGTATCGGAAGGACGTGGCCCGGCGCAC
CGTCGCGGGCCTAGGAGAAG

Downstream 100 bases:

>100_bases
CAACTTCACAAGGGAGGCCTCGATGACGCGGTCGTACGATTCGGCCACGGTCAAGATCGCCGATTTCGACCAGCCGCGTG
CGGAGGCGGCGGTGCGCGAA

Product: Mername-AA223 peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 783; Mature: 783

Protein sequence:

>783_residues
MNRKNVIRTLIVIAVVLLLGWSFFYFSDDTRGFKPVDTSVAISQINSDNVKSAQIDDREQQLRLELKSGNGETEDSDKIL
TKYPTGYAVTLFESLQDKNVKINTVVNQGSVLGSLLIYMLPLLLLVALFVFFSRMQTGGRMGFGFGKSRAKQLTKDMPKT
TFADVAGADEAVEELYEIKDFLQNPSRYQALGAKIPRGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVG
ASRVRDLFEQAKQNSPSIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFGDRQGVILIAATNRPDILDPALLR
PGRFDRQIPVTSPDLAGRRAVLKVHSQGKPMAGDADLDGLAKRTVGMSGADLANVINEAALLTARENGTVITGLALEEAV
DRVVGGPRRKSRIISEHEKKITAYHEGGHTLAAWAMPDIEPIYKVTILARGRTGGHAVAVPEDDKGLMTRSEMISRLVFA
MGGRAAEELVFREPTTGAVSDIQQATKIARAMVTEYGMSSKLGAVRYGTEHGDPFLGRTMGTSSDYSHEVAQIIDDEVRK
LIEAAHTEAWEILTEYRDILDTLAGELLEKETLHRVELEAIFGDVKKRPRLTMFDDFGGRVPSDKPPIKTPGELAIERGE
EWPQPKPEPAFKAAIAAASKAAEEAAARSNGANGSSGANGSPNGAPNGATQPDYGAPAGWHAPGWPPQQQPSGQQGGYWY
PPPSPNPGWGEPPRQQQPYPPYQQHYPQPGHGPQGANPPRDPQQERGRDGDRPGDRPNPPAQH

Sequences:

>Translated_783_residues
MNRKNVIRTLIVIAVVLLLGWSFFYFSDDTRGFKPVDTSVAISQINSDNVKSAQIDDREQQLRLELKSGNGETEDSDKIL
TKYPTGYAVTLFESLQDKNVKINTVVNQGSVLGSLLIYMLPLLLLVALFVFFSRMQTGGRMGFGFGKSRAKQLTKDMPKT
TFADVAGADEAVEELYEIKDFLQNPSRYQALGAKIPRGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVG
ASRVRDLFEQAKQNSPSIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFGDRQGVILIAATNRPDILDPALLR
PGRFDRQIPVTSPDLAGRRAVLKVHSQGKPMAGDADLDGLAKRTVGMSGADLANVINEAALLTARENGTVITGLALEEAV
DRVVGGPRRKSRIISEHEKKITAYHEGGHTLAAWAMPDIEPIYKVTILARGRTGGHAVAVPEDDKGLMTRSEMISRLVFA
MGGRAAEELVFREPTTGAVSDIQQATKIARAMVTEYGMSSKLGAVRYGTEHGDPFLGRTMGTSSDYSHEVAQIIDDEVRK
LIEAAHTEAWEILTEYRDILDTLAGELLEKETLHRVELEAIFGDVKKRPRLTMFDDFGGRVPSDKPPIKTPGELAIERGE
EWPQPKPEPAFKAAIAAASKAAEEAAARSNGANGSSGANGSPNGAPNGATQPDYGAPAGWHAPGWPPQQQPSGQQGGYWY
PPPSPNPGWGEPPRQQQPYPPYQQHYPQPGHGPQGANPPRDPQQERGRDGDRPGDRPNPPAQH
>Mature_783_residues
MNRKNVIRTLIVIAVVLLLGWSFFYFSDDTRGFKPVDTSVAISQINSDNVKSAQIDDREQQLRLELKSGNGETEDSDKIL
TKYPTGYAVTLFESLQDKNVKINTVVNQGSVLGSLLIYMLPLLLLVALFVFFSRMQTGGRMGFGFGKSRAKQLTKDMPKT
TFADVAGADEAVEELYEIKDFLQNPSRYQALGAKIPRGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVG
ASRVRDLFEQAKQNSPSIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFGDRQGVILIAATNRPDILDPALLR
PGRFDRQIPVTSPDLAGRRAVLKVHSQGKPMAGDADLDGLAKRTVGMSGADLANVINEAALLTARENGTVITGLALEEAV
DRVVGGPRRKSRIISEHEKKITAYHEGGHTLAAWAMPDIEPIYKVTILARGRTGGHAVAVPEDDKGLMTRSEMISRLVFA
MGGRAAEELVFREPTTGAVSDIQQATKIARAMVTEYGMSSKLGAVRYGTEHGDPFLGRTMGTSSDYSHEVAQIIDDEVRK
LIEAAHTEAWEILTEYRDILDTLAGELLEKETLHRVELEAIFGDVKKRPRLTMFDDFGGRVPSDKPPIKTPGELAIERGE
EWPQPKPEPAFKAAIAAASKAAEEAAARSNGANGSSGANGSPNGAPNGATQPDYGAPAGWHAPGWPPQQQPSGQQGGYWY
PPPSPNPGWGEPPRQQQPYPPYQQHYPQPGHGPQGANPPRDPQQERGRDGDRPGDRPNPPAQH

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins [H]

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family [H]

Homologues:

Organism=Homo sapiens, GI300192933, Length=506, Percent_Identity=47.0355731225296, Blast_Score=442, Evalue=1e-124,
Organism=Homo sapiens, GI21327685, Length=448, Percent_Identity=45.9821428571429, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI7657689, Length=448, Percent_Identity=45.9821428571429, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI4507173, Length=564, Percent_Identity=39.5390070921986, Blast_Score=369, Evalue=1e-102,
Organism=Homo sapiens, GI24497435, Length=253, Percent_Identity=42.2924901185771, Blast_Score=205, Evalue=1e-52,
Organism=Homo sapiens, GI4506209, Length=252, Percent_Identity=41.2698412698413, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI24430151, Length=248, Percent_Identity=40.3225806451613, Blast_Score=203, Evalue=6e-52,
Organism=Homo sapiens, GI195539395, Length=255, Percent_Identity=39.6078431372549, Blast_Score=196, Evalue=7e-50,
Organism=Homo sapiens, GI6005942, Length=231, Percent_Identity=44.1558441558442, Blast_Score=196, Evalue=7e-50,
Organism=Homo sapiens, GI21361144, Length=247, Percent_Identity=41.7004048582996, Blast_Score=193, Evalue=5e-49,
Organism=Homo sapiens, GI89064750, Length=259, Percent_Identity=39.7683397683398, Blast_Score=192, Evalue=8e-49,
Organism=Homo sapiens, GI5729991, Length=259, Percent_Identity=39.7683397683398, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI24430155, Length=259, Percent_Identity=39.7683397683398, Blast_Score=192, Evalue=2e-48,
Organism=Homo sapiens, GI157671927, Length=241, Percent_Identity=40.6639004149378, Blast_Score=189, Evalue=1e-47,
Organism=Homo sapiens, GI45643123, Length=278, Percent_Identity=38.8489208633094, Blast_Score=184, Evalue=3e-46,
Organism=Homo sapiens, GI45643125, Length=278, Percent_Identity=38.8489208633094, Blast_Score=184, Evalue=4e-46,
Organism=Homo sapiens, GI229577436, Length=253, Percent_Identity=39.5256916996047, Blast_Score=173, Evalue=6e-43,
Organism=Homo sapiens, GI24497618, Length=231, Percent_Identity=41.1255411255411, Blast_Score=165, Evalue=2e-40,
Organism=Homo sapiens, GI4505725, Length=242, Percent_Identity=37.603305785124, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI153792536, Length=231, Percent_Identity=40.2597402597403, Blast_Score=163, Evalue=6e-40,
Organism=Homo sapiens, GI40806173, Length=252, Percent_Identity=41.2698412698413, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI14149767, Length=276, Percent_Identity=34.7826086956522, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI62177112, Length=276, Percent_Identity=34.7826086956522, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI5901990, Length=268, Percent_Identity=36.1940298507463, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI226371754, Length=239, Percent_Identity=37.6569037656904, Blast_Score=139, Evalue=9e-33,
Organism=Homo sapiens, GI17865802, Length=240, Percent_Identity=37.9166666666667, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI7019569, Length=240, Percent_Identity=36.6666666666667, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI194018488, Length=227, Percent_Identity=39.2070484581498, Blast_Score=137, Evalue=4e-32,
Organism=Homo sapiens, GI11875211, Length=233, Percent_Identity=40.343347639485, Blast_Score=133, Evalue=6e-31,
Organism=Homo sapiens, GI40806170, Length=233, Percent_Identity=40.343347639485, Blast_Score=133, Evalue=7e-31,
Organism=Homo sapiens, GI156564401, Length=214, Percent_Identity=37.8504672897196, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI31377644, Length=236, Percent_Identity=36.0169491525424, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI31742536, Length=228, Percent_Identity=32.0175438596491, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI112789543, Length=228, Percent_Identity=32.0175438596491, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI310125282, Length=214, Percent_Identity=36.4485981308411, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI310125280, Length=211, Percent_Identity=37.4407582938389, Blast_Score=126, Evalue=9e-29,
Organism=Homo sapiens, GI64084766, Length=190, Percent_Identity=31.0526315789474, Blast_Score=103, Evalue=9e-22,
Organism=Homo sapiens, GI116292174, Length=268, Percent_Identity=29.4776119402985, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI75677353, Length=272, Percent_Identity=28.3088235294118, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI4757852, Length=158, Percent_Identity=32.2784810126582, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI119964730, Length=158, Percent_Identity=32.2784810126582, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI283436220, Length=220, Percent_Identity=30, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI283436222, Length=220, Percent_Identity=30, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI283436224, Length=220, Percent_Identity=30, Blast_Score=68, Evalue=4e-11,
Organism=Escherichia coli, GI1789568, Length=611, Percent_Identity=50.2454991816694, Blast_Score=563, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI71994521, Length=469, Percent_Identity=47.7611940298507, Blast_Score=407, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17554264, Length=445, Percent_Identity=46.2921348314607, Blast_Score=367, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI115534323, Length=458, Percent_Identity=42.3580786026201, Blast_Score=340, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI17554786, Length=380, Percent_Identity=36.8421052631579, Blast_Score=215, Evalue=7e-56,
Organism=Caenorhabditis elegans, GI25144278, Length=253, Percent_Identity=43.0830039525692, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI25144281, Length=253, Percent_Identity=43.0830039525692, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17563248, Length=254, Percent_Identity=43.3070866141732, Blast_Score=210, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17532375, Length=249, Percent_Identity=40.9638554216867, Blast_Score=206, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17563250, Length=248, Percent_Identity=39.9193548387097, Blast_Score=196, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17505546, Length=248, Percent_Identity=41.1290322580645, Blast_Score=194, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17531535, Length=250, Percent_Identity=42, Blast_Score=192, Evalue=8e-49,
Organism=Caenorhabditis elegans, GI71987364, Length=254, Percent_Identity=39.3700787401575, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI71987372, Length=254, Percent_Identity=39.3700787401575, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17508701, Length=246, Percent_Identity=40.2439024390244, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17554784, Length=248, Percent_Identity=42.741935483871, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17508053, Length=261, Percent_Identity=40.9961685823755, Blast_Score=182, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17537217, Length=279, Percent_Identity=38.3512544802867, Blast_Score=168, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI133931034, Length=234, Percent_Identity=41.025641025641, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI193206114, Length=234, Percent_Identity=41.025641025641, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI193206116, Length=234, Percent_Identity=41.025641025641, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI25153574, Length=203, Percent_Identity=36.9458128078818, Blast_Score=145, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI193209502, Length=203, Percent_Identity=36.9458128078818, Blast_Score=142, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI133901658, Length=212, Percent_Identity=39.1509433962264, Blast_Score=138, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI133901662, Length=209, Percent_Identity=38.755980861244, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17562804, Length=232, Percent_Identity=35.3448275862069, Blast_Score=136, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=41.8181818181818, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=41.8181818181818, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI86561515, Length=239, Percent_Identity=33.8912133891213, Blast_Score=129, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17508421, Length=233, Percent_Identity=38.1974248927039, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32563584, Length=229, Percent_Identity=38.4279475982533, Blast_Score=126, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI25146157, Length=231, Percent_Identity=38.5281385281385, Blast_Score=125, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17541226, Length=237, Percent_Identity=35.8649789029536, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17541224, Length=237, Percent_Identity=35.8649789029536, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17560432, Length=234, Percent_Identity=34.1880341880342, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71990294, Length=227, Percent_Identity=29.9559471365639, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71990335, Length=160, Percent_Identity=31.25, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71990340, Length=160, Percent_Identity=31.25, Blast_Score=67, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323736, Length=534, Percent_Identity=46.2546816479401, Blast_Score=447, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6320854, Length=495, Percent_Identity=47.0707070707071, Blast_Score=436, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6325281, Length=450, Percent_Identity=45.3333333333333, Blast_Score=372, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6321390, Length=254, Percent_Identity=41.3385826771654, Blast_Score=210, Evalue=8e-55,
Organism=Saccharomyces cerevisiae, GI6322704, Length=259, Percent_Identity=40.5405405405405, Blast_Score=204, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6320197, Length=248, Percent_Identity=39.9193548387097, Blast_Score=202, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6320077, Length=237, Percent_Identity=43.8818565400844, Blast_Score=201, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6320602, Length=244, Percent_Identity=44.2622950819672, Blast_Score=194, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6324833, Length=246, Percent_Identity=41.869918699187, Blast_Score=194, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6324691, Length=270, Percent_Identity=39.6296296296296, Blast_Score=187, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6323429, Length=242, Percent_Identity=38.8429752066116, Blast_Score=167, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6321709, Length=232, Percent_Identity=41.3793103448276, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6322994, Length=234, Percent_Identity=36.7521367521368, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6322651, Length=264, Percent_Identity=35.9848484848485, Blast_Score=154, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6324000, Length=230, Percent_Identity=38.695652173913, Blast_Score=154, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6325431, Length=234, Percent_Identity=39.7435897435897, Blast_Score=146, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6319554, Length=213, Percent_Identity=35.6807511737089, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6321465, Length=237, Percent_Identity=35.0210970464135, Blast_Score=120, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6320887, Length=270, Percent_Identity=34.8148148148148, Blast_Score=118, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6325183, Length=245, Percent_Identity=34.2857142857143, Blast_Score=118, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6320583, Length=191, Percent_Identity=31.413612565445, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28574878, Length=612, Percent_Identity=39.7058823529412, Blast_Score=426, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24665814, Length=512, Percent_Identity=44.140625, Blast_Score=424, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24639391, Length=439, Percent_Identity=46.4692482915718, Blast_Score=382, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24658770, Length=495, Percent_Identity=42.4242424242424, Blast_Score=375, Evalue=1e-104,
Organism=Drosophila melanogaster, GI19920408, Length=368, Percent_Identity=37.5, Blast_Score=207, Evalue=3e-53,
Organism=Drosophila melanogaster, GI161076488, Length=240, Percent_Identity=39.5833333333333, Blast_Score=203, Evalue=5e-52,
Organism=Drosophila melanogaster, GI17137560, Length=240, Percent_Identity=39.5833333333333, Blast_Score=202, Evalue=5e-52,
Organism=Drosophila melanogaster, GI161076486, Length=240, Percent_Identity=39.5833333333333, Blast_Score=202, Evalue=6e-52,
Organism=Drosophila melanogaster, GI24649446, Length=248, Percent_Identity=40.7258064516129, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI17137738, Length=252, Percent_Identity=41.2698412698413, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24651451, Length=253, Percent_Identity=41.897233201581, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI45554047, Length=163, Percent_Identity=58.2822085889571, Blast_Score=199, Evalue=7e-51,
Organism=Drosophila melanogaster, GI281361487, Length=242, Percent_Identity=41.7355371900826, Blast_Score=192, Evalue=7e-49,
Organism=Drosophila melanogaster, GI17738151, Length=247, Percent_Identity=39.6761133603239, Blast_Score=192, Evalue=1e-48,
Organism=Drosophila melanogaster, GI18860063, Length=242, Percent_Identity=40.9090909090909, Blast_Score=190, Evalue=3e-48,
Organism=Drosophila melanogaster, GI281365776, Length=235, Percent_Identity=41.7021276595745, Blast_Score=189, Evalue=6e-48,
Organism=Drosophila melanogaster, GI24660075, Length=235, Percent_Identity=41.7021276595745, Blast_Score=189, Evalue=7e-48,
Organism=Drosophila melanogaster, GI45552965, Length=235, Percent_Identity=41.7021276595745, Blast_Score=189, Evalue=9e-48,
Organism=Drosophila melanogaster, GI24640100, Length=255, Percent_Identity=39.2156862745098, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24663015, Length=255, Percent_Identity=38.0392156862745, Blast_Score=185, Evalue=8e-47,
Organism=Drosophila melanogaster, GI19921202, Length=237, Percent_Identity=39.662447257384, Blast_Score=184, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24652279, Length=190, Percent_Identity=44.2105263157895, Blast_Score=182, Evalue=6e-46,
Organism=Drosophila melanogaster, GI24656825, Length=224, Percent_Identity=41.0714285714286, Blast_Score=169, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24656820, Length=224, Percent_Identity=41.0714285714286, Blast_Score=169, Evalue=7e-42,
Organism=Drosophila melanogaster, GI281363136, Length=273, Percent_Identity=39.1941391941392, Blast_Score=159, Evalue=9e-39,
Organism=Drosophila melanogaster, GI78707192, Length=273, Percent_Identity=39.1941391941392, Blast_Score=159, Evalue=9e-39,
Organism=Drosophila melanogaster, GI18859657, Length=238, Percent_Identity=38.655462184874, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI21355121, Length=213, Percent_Identity=36.150234741784, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24644145, Length=252, Percent_Identity=37.3015873015873, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI28571849, Length=238, Percent_Identity=40.3361344537815, Blast_Score=136, Evalue=6e-32,
Organism=Drosophila melanogaster, GI28571847, Length=238, Percent_Identity=40.3361344537815, Blast_Score=136, Evalue=6e-32,
Organism=Drosophila melanogaster, GI281360136, Length=247, Percent_Identity=34.0080971659919, Blast_Score=132, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24644411, Length=247, Percent_Identity=34.0080971659919, Blast_Score=132, Evalue=8e-31,
Organism=Drosophila melanogaster, GI281360144, Length=247, Percent_Identity=34.0080971659919, Blast_Score=132, Evalue=8e-31,
Organism=Drosophila melanogaster, GI281360140, Length=247, Percent_Identity=34.0080971659919, Blast_Score=132, Evalue=8e-31,
Organism=Drosophila melanogaster, GI281360146, Length=241, Percent_Identity=34.8547717842324, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281360138, Length=241, Percent_Identity=34.8547717842324, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281360142, Length=247, Percent_Identity=34.0080971659919, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21357333, Length=247, Percent_Identity=34.0080971659919, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI20129423, Length=236, Percent_Identity=33.8983050847458, Blast_Score=129, Evalue=7e-30,
Organism=Drosophila melanogaster, GI28573010, Length=211, Percent_Identity=36.4928909952607, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI17864540, Length=211, Percent_Identity=36.9668246445498, Blast_Score=127, Evalue=4e-29,
Organism=Drosophila melanogaster, GI20129529, Length=233, Percent_Identity=32.618025751073, Blast_Score=125, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24581396, Length=233, Percent_Identity=35.6223175965665, Blast_Score=120, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24639486, Length=190, Percent_Identity=35.7894736842105, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI20129417, Length=152, Percent_Identity=34.8684210526316, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24583262, Length=152, Percent_Identity=34.8684210526316, Blast_Score=74, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR000642 [H]

Pfam domain/function: PF00004 AAA; PF01434 Peptidase_M41 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 84854; Mature: 84854

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MNRKNVIRTLIVIAVVLLLGWSFFYFSDDTRGFKPVDTSVAISQINSDNVKSAQIDDREQ
CCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHH
QLRLELKSGNGETEDSDKILTKYPTGYAVTLFESLQDKNVKINTVVNQGSVLGSLLIYML
HEEEEEECCCCCCCCCCCEEEECCCCCEEHHHHHHCCCCEEEEEEECCHHHHHHHHHHHH
PLLLLVALFVFFSRMQTGGRMGFGFGKSRAKQLTKDMPKTTFADVAGADEAVEELYEIKD
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHH
FLQNPSRYQALGAKIPRGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVG
HHCCCHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHCC
ASRVRDLFEQAKQNSPSIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFGDRQ
HHHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
GVILIAATNRPDILDPALLRPGRFDRQIPVTSPDLAGRRAVLKVHSQGKPMAGDADLDGL
CEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHH
AKRTVGMSGADLANVINEAALLTARENGTVITGLALEEAVDRVVGGPRRKSRIISEHEKK
HHHHCCCCCHHHHHHHHHHHEEEECCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ITAYHEGGHTLAAWAMPDIEPIYKVTILARGRTGGHAVAVPEDDKGLMTRSEMISRLVFA
EEEEECCCCEEEEECCCCCCCCEEEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHH
MGGRAAEELVFREPTTGAVSDIQQATKIARAMVTEYGMSSKLGAVRYGTEHGDPFLGRTM
HCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCC
GTSSDYSHEVAQIIDDEVRKLIEAAHTEAWEILTEYRDILDTLAGELLEKETLHRVELEA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFGDVKKRPRLTMFDDFGGRVPSDKPPIKTPGELAIERGEEWPQPKPEPAFKAAIAAASK
HHHHHHCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AAEEAAARSNGANGSSGANGSPNGAPNGATQPDYGAPAGWHAPGWPPQQQPSGQQGGYWY
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEC
PPPSPNPGWGEPPRQQQPYPPYQQHYPQPGHGPQGANPPRDPQQERGRDGDRPGDRPNPP
CCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCC
AQH
CCC
>Mature Secondary Structure
MNRKNVIRTLIVIAVVLLLGWSFFYFSDDTRGFKPVDTSVAISQINSDNVKSAQIDDREQ
CCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHH
QLRLELKSGNGETEDSDKILTKYPTGYAVTLFESLQDKNVKINTVVNQGSVLGSLLIYML
HEEEEEECCCCCCCCCCCEEEECCCCCEEHHHHHHCCCCEEEEEEECCHHHHHHHHHHHH
PLLLLVALFVFFSRMQTGGRMGFGFGKSRAKQLTKDMPKTTFADVAGADEAVEELYEIKD
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHH
FLQNPSRYQALGAKIPRGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVG
HHCCCHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHCC
ASRVRDLFEQAKQNSPSIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFGDRQ
HHHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
GVILIAATNRPDILDPALLRPGRFDRQIPVTSPDLAGRRAVLKVHSQGKPMAGDADLDGL
CEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHH
AKRTVGMSGADLANVINEAALLTARENGTVITGLALEEAVDRVVGGPRRKSRIISEHEKK
HHHHCCCCCHHHHHHHHHHHEEEECCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ITAYHEGGHTLAAWAMPDIEPIYKVTILARGRTGGHAVAVPEDDKGLMTRSEMISRLVFA
EEEEECCCCEEEEECCCCCCCCEEEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHH
MGGRAAEELVFREPTTGAVSDIQQATKIARAMVTEYGMSSKLGAVRYGTEHGDPFLGRTM
HCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCC
GTSSDYSHEVAQIIDDEVRKLIEAAHTEAWEILTEYRDILDTLAGELLEKETLHRVELEA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFGDVKKRPRLTMFDDFGGRVPSDKPPIKTPGELAIERGEEWPQPKPEPAFKAAIAAASK
HHHHHHCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AAEEAAARSNGANGSSGANGSPNGAPNGATQPDYGAPAGWHAPGWPPQQQPSGQQGGYWY
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEC
PPPSPNPGWGEPPRQQQPYPPYQQHYPQPGHGPQGANPPRDPQQERGRDGDRPGDRPNPP
CCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCC
AQH
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]