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The map label for this gene is resE [H]

Identifier: 108801616

GI number: 108801616

Start: 4930365

End: 4931660

Strand: Reverse

Name: resE [H]

Synonym: Mmcs_4653

Alternate gene names: 108801616

Gene position: 4931660-4930365 (Counterclockwise)

Preceding gene: 108801618

Following gene: 108801615

Centisome position: 86.44

GC content: 69.6

Gene sequence:

>1296_bases
GTGAACGGCTCGCGTCGACTGAGGTCACTGGTGGTGCCCGCCGGGGACACCTACGGTCTGGCGCGGGTCGTGGTGGCCGT
CCGCGCCGCGGTGGTGTTGTCGGTCGTCCTGCTGAGCGCGACCGGTCCGGATTGGATGCGCCGCAATCCTGTGGTGTTGA
CGATCGTGCTGGCGGCCGCACTCGTGTACGCGGCCGTGTTGATGGCCCATCCGCGCTACGAGGTGCGGCGCACCCGCTTC
GCCTGGTTGGTGGCCGCGCTGGACGCGACGTTCACGTTGACGCTGATCGCCCTCACCGGAGGTGCCTCCAGTCCCGTCGT
CGCCGTCCTCGCACTGGTCGTGATCGCGTCCGCGGCCAGGTTGACCTTTCTCGAATGTCTCTCACTCGCAATCCTTCTGG
GTCTCGGATACCTCGCGGTGGTGTCCTTTGTCACCGCCGGTGGCGCTGCACTCGCACCGCTGACCCTGGGCCTCTGGTGG
GCGCTGTACATGGTGTTCATCGCCGTGCTGAGCGGTGGGCTGGCGGTCTTGATCGAACGTGAGCACCGATCACGGGTGGA
CGCCCTGGTGGAAGCCGAGGCCGAACACGCCGCGGCCGCGGAGGAACGCGACCTGCGCGCGCGCCTGCTCCGTTCCTACG
AGGCGCAGCAGGAGGGACTACAGGTGCTGCTGCACGAATTCCGCACCCCGGTGGCCTCACTGGACGCCCTGGCCGGCGCA
CTCACCGACACCACACCGATGCCAGATGCCGACCGGGATGCGGCGATTCGACTCGCCGGTCGGCATGCCCGGCACCTCAC
CGACATGCTCGACGCCCTCTCCGACGTCAACCTCAGCCGCCAACCCGCCTTCTCCTCCGGGCGGGTGCGCCGCGTCGACG
TCGCGGAACTGGTCAGCGAGGCCGGTCATGCGGTGGATCTCGGTCCGCCCCGGCTGCGGGTGTCGACGACCGGTGACGTC
TCGGCAGTGTCGATCGATGCGCAGGGCCTGCGCCGTGTCCTGACCAACCTGCTGGAGAACGCGGCCCGCCACGGCCGGGA
CCGGCCCATCGACGTCGAATGCGAACGCCTCGACGACCGACTAAGGGTCAGCGTGTCGGACCGTGGCCCGGGGGTCCCCC
AGGCGGCCCTGGGCGAGCTGACCGGCAAGTTCGTCAGCCTGTCGGATCGGCGCGGCACCGCCGGTCTGGGGTTGTGGATC
GTGCAGCAGATCATCGACGCCCTCGGCGGCACGCTGCAATTCACCGCCCGCGCCGAGGGTGGCCTCACGGCGTCGTTCAC
CGTTCCGGTCGGCTGA

Upstream 100 bases:

>100_bases
GAACAATTCGTGATCGTCGACGATCACGACGACGAGGGGTTCTCGTCCGGACCTGTGAGTCACCCGCTGGATCGTAGTGC
GCGGGTCTAGGGTCGGCCCC

Downstream 100 bases:

>100_bases
GCGCCCGAGGTCCCCGGGGCCGGCGACGTGGCCCGCACGGGCCGCCATTGGCCCGCACGGCGGCTCCGTCGGGCGTCGTG
GTGTCCAACACTGGGCCTTG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MNGSRRLRSLVVPAGDTYGLARVVVAVRAAVVLSVVLLSATGPDWMRRNPVVLTIVLAAALVYAAVLMAHPRYEVRRTRF
AWLVAALDATFTLTLIALTGGASSPVVAVLALVVIASAARLTFLECLSLAILLGLGYLAVVSFVTAGGAALAPLTLGLWW
ALYMVFIAVLSGGLAVLIEREHRSRVDALVEAEAEHAAAAEERDLRARLLRSYEAQQEGLQVLLHEFRTPVASLDALAGA
LTDTTPMPDADRDAAIRLAGRHARHLTDMLDALSDVNLSRQPAFSSGRVRRVDVAELVSEAGHAVDLGPPRLRVSTTGDV
SAVSIDAQGLRRVLTNLLENAARHGRDRPIDVECERLDDRLRVSVSDRGPGVPQAALGELTGKFVSLSDRRGTAGLGLWI
VQQIIDALGGTLQFTARAEGGLTASFTVPVG

Sequences:

>Translated_431_residues
MNGSRRLRSLVVPAGDTYGLARVVVAVRAAVVLSVVLLSATGPDWMRRNPVVLTIVLAAALVYAAVLMAHPRYEVRRTRF
AWLVAALDATFTLTLIALTGGASSPVVAVLALVVIASAARLTFLECLSLAILLGLGYLAVVSFVTAGGAALAPLTLGLWW
ALYMVFIAVLSGGLAVLIEREHRSRVDALVEAEAEHAAAAEERDLRARLLRSYEAQQEGLQVLLHEFRTPVASLDALAGA
LTDTTPMPDADRDAAIRLAGRHARHLTDMLDALSDVNLSRQPAFSSGRVRRVDVAELVSEAGHAVDLGPPRLRVSTTGDV
SAVSIDAQGLRRVLTNLLENAARHGRDRPIDVECERLDDRLRVSVSDRGPGVPQAALGELTGKFVSLSDRRGTAGLGLWI
VQQIIDALGGTLQFTARAEGGLTASFTVPVG
>Mature_431_residues
MNGSRRLRSLVVPAGDTYGLARVVVAVRAAVVLSVVLLSATGPDWMRRNPVVLTIVLAAALVYAAVLMAHPRYEVRRTRF
AWLVAALDATFTLTLIALTGGASSPVVAVLALVVIASAARLTFLECLSLAILLGLGYLAVVSFVTAGGAALAPLTLGLWW
ALYMVFIAVLSGGLAVLIEREHRSRVDALVEAEAEHAAAAEERDLRARLLRSYEAQQEGLQVLLHEFRTPVASLDALAGA
LTDTTPMPDADRDAAIRLAGRHARHLTDMLDALSDVNLSRQPAFSSGRVRRVDVAELVSEAGHAVDLGPPRLRVSTTGDV
SAVSIDAQGLRRVLTNLLENAARHGRDRPIDVECERLDDRLRVSVSDRGPGVPQAALGELTGKFVSLSDRRGTAGLGLWI
VQQIIDALGGTLQFTARAEGGLTASFTVPVG

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=272, Percent_Identity=30.1470588235294, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788713, Length=255, Percent_Identity=25.0980392156863, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1786912, Length=217, Percent_Identity=28.110599078341, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790551, Length=203, Percent_Identity=31.0344827586207, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45765; Mature: 45765

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGSRRLRSLVVPAGDTYGLARVVVAVRAAVVLSVVLLSATGPDWMRRNPVVLTIVLAAA
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHH
LVYAAVLMAHPRYEVRRTRFAWLVAALDATFTLTLIALTGGASSPVVAVLALVVIASAAR
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHH
LTFLECLSLAILLGLGYLAVVSFVTAGGAALAPLTLGLWWALYMVFIAVLSGGLAVLIER
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
EHRSRVDALVEAEAEHAAAAEERDLRARLLRSYEAQQEGLQVLLHEFRTPVASLDALAGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LTDTTPMPDADRDAAIRLAGRHARHLTDMLDALSDVNLSRQPAFSSGRVRRVDVAELVSE
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECHHHHHHH
AGHAVDLGPPRLRVSTTGDVSAVSIDAQGLRRVLTNLLENAARHGRDRPIDVECERLDDR
CCCEEECCCCCEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCC
LRVSVSDRGPGVPQAALGELTGKFVSLSDRRGTAGLGLWIVQQIIDALGGTLQFTARAEG
EEEEECCCCCCCCHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCC
GLTASFTVPVG
CEEEEEEECCC
>Mature Secondary Structure
MNGSRRLRSLVVPAGDTYGLARVVVAVRAAVVLSVVLLSATGPDWMRRNPVVLTIVLAAA
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHH
LVYAAVLMAHPRYEVRRTRFAWLVAALDATFTLTLIALTGGASSPVVAVLALVVIASAAR
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHH
LTFLECLSLAILLGLGYLAVVSFVTAGGAALAPLTLGLWWALYMVFIAVLSGGLAVLIER
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
EHRSRVDALVEAEAEHAAAAEERDLRARLLRSYEAQQEGLQVLLHEFRTPVASLDALAGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LTDTTPMPDADRDAAIRLAGRHARHLTDMLDALSDVNLSRQPAFSSGRVRRVDVAELVSE
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECHHHHHHH
AGHAVDLGPPRLRVSTTGDVSAVSIDAQGLRRVLTNLLENAARHGRDRPIDVECERLDDR
CCCEEECCCCCEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCC
LRVSVSDRGPGVPQAALGELTGKFVSLSDRRGTAGLGLWIVQQIIDALGGTLQFTARAEG
EEEEECCCCCCCCHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCC
GLTASFTVPVG
CEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]