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The map label for this gene is adhB [H]

Identifier: 108801614

GI number: 108801614

Start: 4927793

End: 4928899

Strand: Reverse

Name: adhB [H]

Synonym: Mmcs_4651

Alternate gene names: 108801614

Gene position: 4928899-4927793 (Counterclockwise)

Preceding gene: 108801615

Following gene: 108801613

Centisome position: 86.39

GC content: 68.11

Gene sequence:

>1107_bases
TTGAAGACGAAAGCCGCTGTCCTGTGGGGGCTGCACCAGAAATGGGAGGTCACCGAACTCGACCTCGACGCGCCCAAGGC
GCAGGAGGTCCTGGTCAAGCTGACCGCGAGCGGGCTCTGCCACTCCGATGACCACCTGGTCACCGGGGACATGCCGATGA
ATCTGCCGGTGGTGGGCGGACACGAGGGCGCCGGTGTGGTCGCCGAGGTCGGCCCCGGCGTGACCGAGGTCGAGGTCGGC
GACCACGTGGTGCTGAGCTTCATCCCGGCCTGCGGCCGCTGCACCGAATGTGCGCGAGGGCGCAGCAACCTGTGCGTGTA
CGGCGCCGCGATCGTCGCCGGGCCGCAACTCGACGGCACCTACAGGTTCCACAGCGGCGGGCAGGACGTCGGCCAGATGT
GTGTGCTGGGCACCTTCTCGGAGTACACCGTGGTGCCGATCGCCTCGGTGGTCAAGGTGGACAAGGACATTCCGCTGGAC
AAGGCAGCACTGGTCGGGTGTGGGGTCACCACCGGTTACGGTGCCGCCGTGCGCACCGGTGAGGCCCGCGACGGCGACAC
CGTCGTGGTCATGGGTGTCGGCGGGCTCGGTATCAACGCGGTCCAGGGCGCCAGGCTCGCCGGCGCGCGCTACGTCGTCG
CCCTCGATCCCGTCGCCTACAAGCGGGAGCGGTCCTTCGAGTTCGGCGCCACCCACGCCGCGGCCACCGTCGAGGAGGCG
CAGGCACTGATCACCGACCTGACCCGCGGCACCATGGCCGACGTCTGCGTGGTCACCACCGACAGTGCCGAAGGCGCCTA
CGTGGCGCAGGGCCTGAGCCTGGTCGGCAAGCGCGGCCGAGTGGTGATGACGGCGATCCCGCACCCGACCGACACCACCG
TCGACATGTCGCTGTTCGACCTGACCCTGTACGAAAAGCAGGTCAGGGGATGCCTTTTCGGGTCATCCAACCCGCGCCTG
GACATCCCGCGCATGCTCGAACTCTTCGGGTCCGGCCGTCTCATGCTCGACGAGCTGATCACCCGCGAGTACACCCTCGA
CGAGATCAACCAGGGGTACGAGGACATGCACGACGGGCGCAATCTGCGCGGGCTGATCAGGTTCTGA

Upstream 100 bases:

>100_bases
AGGTCGCCAACTTCATCAACGGCATCAACAGCCTGCCCGCCACCTGGACCCCCGAACGCCGCTGACGACCCTGACCCACT
GACCGAGAGGAATCACGATC

Downstream 100 bases:

>100_bases
TGATGACCGGACTTCCGCATTACCGGATGTACGTCGACGGCGAGTGGCGCGACGCCGCGGAGTCGATCGAGGTGCGCAGC
CCGGCAACCGGCGCCCCCGT

Product: alcohol dehydrogenase GroES-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKTKAAVLWGLHQKWEVTELDLDAPKAQEVLVKLTASGLCHSDDHLVTGDMPMNLPVVGGHEGAGVVAEVGPGVTEVEVG
DHVVLSFIPACGRCTECARGRSNLCVYGAAIVAGPQLDGTYRFHSGGQDVGQMCVLGTFSEYTVVPIASVVKVDKDIPLD
KAALVGCGVTTGYGAAVRTGEARDGDTVVVMGVGGLGINAVQGARLAGARYVVALDPVAYKRERSFEFGATHAAATVEEA
QALITDLTRGTMADVCVVTTDSAEGAYVAQGLSLVGKRGRVVMTAIPHPTDTTVDMSLFDLTLYEKQVRGCLFGSSNPRL
DIPRMLELFGSGRLMLDELITREYTLDEINQGYEDMHDGRNLRGLIRF

Sequences:

>Translated_368_residues
MKTKAAVLWGLHQKWEVTELDLDAPKAQEVLVKLTASGLCHSDDHLVTGDMPMNLPVVGGHEGAGVVAEVGPGVTEVEVG
DHVVLSFIPACGRCTECARGRSNLCVYGAAIVAGPQLDGTYRFHSGGQDVGQMCVLGTFSEYTVVPIASVVKVDKDIPLD
KAALVGCGVTTGYGAAVRTGEARDGDTVVVMGVGGLGINAVQGARLAGARYVVALDPVAYKRERSFEFGATHAAATVEEA
QALITDLTRGTMADVCVVTTDSAEGAYVAQGLSLVGKRGRVVMTAIPHPTDTTVDMSLFDLTLYEKQVRGCLFGSSNPRL
DIPRMLELFGSGRLMLDELITREYTLDEINQGYEDMHDGRNLRGLIRF
>Mature_368_residues
MKTKAAVLWGLHQKWEVTELDLDAPKAQEVLVKLTASGLCHSDDHLVTGDMPMNLPVVGGHEGAGVVAEVGPGVTEVEVG
DHVVLSFIPACGRCTECARGRSNLCVYGAAIVAGPQLDGTYRFHSGGQDVGQMCVLGTFSEYTVVPIASVVKVDKDIPLD
KAALVGCGVTTGYGAAVRTGEARDGDTVVVMGVGGLGINAVQGARLAGARYVVALDPVAYKRERSFEFGATHAAATVEEA
QALITDLTRGTMADVCVVTTDSAEGAYVAQGLSLVGKRGRVVMTAIPHPTDTTVDMSLFDLTLYEKQVRGCLFGSSNPRL
DIPRMLELFGSGRLMLDELITREYTLDEINQGYEDMHDGRNLRGLIRF

Specific function: Has High Formaldehyde Dehydrogenase Activity In The Presence Of Glutathione And Catalyzes The Oxidation Of Normal Alcohols In A Reaction That Is Not Gsh-Dependent. In Addition, Hemithiolacetals Other Than Those Formed From Gsh, Including Omega-Thiol Fatty

COG id: COG1062

COG function: function code C; Zn-dependent alcohol dehydrogenases, class III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI71743840, Length=371, Percent_Identity=34.2318059299191, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI262073058, Length=371, Percent_Identity=34.2318059299191, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI4501933, Length=372, Percent_Identity=34.1397849462366, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI34577061, Length=372, Percent_Identity=34.4086021505376, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI4501929, Length=374, Percent_Identity=34.7593582887701, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI71565154, Length=376, Percent_Identity=33.5106382978723, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI156523966, Length=371, Percent_Identity=32.3450134770889, Blast_Score=201, Evalue=6e-52,
Organism=Homo sapiens, GI4501939, Length=365, Percent_Identity=32.6027397260274, Blast_Score=198, Evalue=6e-51,
Organism=Homo sapiens, GI71565152, Length=378, Percent_Identity=29.8941798941799, Blast_Score=181, Evalue=7e-46,
Organism=Escherichia coli, GI1786552, Length=379, Percent_Identity=35.3562005277045, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI87082125, Length=379, Percent_Identity=24.5382585751979, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790045, Length=347, Percent_Identity=27.0893371757925, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787863, Length=341, Percent_Identity=23.1671554252199, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87081918, Length=363, Percent_Identity=29.7520661157025, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788073, Length=377, Percent_Identity=23.0769230769231, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI226510992, Length=359, Percent_Identity=25.6267409470752, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788407, Length=335, Percent_Identity=23.8805970149254, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786825, Length=386, Percent_Identity=26.1658031088083, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788075, Length=366, Percent_Identity=23.224043715847, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786518, Length=373, Percent_Identity=26.0053619302949, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25146526, Length=385, Percent_Identity=33.5064935064935, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI71997431, Length=387, Percent_Identity=33.3333333333333, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17565904, Length=349, Percent_Identity=31.8051575931232, Blast_Score=172, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI71988145, Length=359, Percent_Identity=30.3621169916435, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17562584, Length=352, Percent_Identity=30.6818181818182, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17562582, Length=358, Percent_Identity=29.608938547486, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562876, Length=371, Percent_Identity=23.989218328841, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17562878, Length=216, Percent_Identity=28.7037037037037, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320033, Length=382, Percent_Identity=35.6020942408377, Blast_Score=216, Evalue=6e-57,
Organism=Saccharomyces cerevisiae, GI6319621, Length=337, Percent_Identity=27.893175074184, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323729, Length=363, Percent_Identity=25.6198347107438, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6324486, Length=361, Percent_Identity=26.3157894736842, Blast_Score=96, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6323961, Length=361, Percent_Identity=25.7617728531856, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6319257, Length=345, Percent_Identity=26.3768115942029, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6319258, Length=239, Percent_Identity=29.2887029288703, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322619, Length=354, Percent_Identity=26.271186440678, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323099, Length=388, Percent_Identity=24.2268041237113, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6319955, Length=368, Percent_Identity=25.8152173913043, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323980, Length=282, Percent_Identity=26.241134751773, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI17737895, Length=383, Percent_Identity=34.2036553524804, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI17137530, Length=341, Percent_Identity=26.099706744868, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17737897, Length=337, Percent_Identity=27.0029673590504, Blast_Score=92, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 39073; Mature: 39073

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKAAVLWGLHQKWEVTELDLDAPKAQEVLVKLTASGLCHSDDHLVTGDMPMNLPVVGG
CCCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEECC
HEGAGVVAEVGPGVTEVEVGDHVVLSFIPACGRCTECARGRSNLCVYGAAIVAGPQLDGT
CCCCCEEEECCCCCEEEECCCEEEEHHHCCCCCHHHHHCCCCCEEEEEEEEEECCCCCCE
YRFHSGGQDVGQMCVLGTFSEYTVVPIASVVKVDKDIPLDKAALVGCGVTTGYGAAVRTG
EEECCCCCCHHCEEEEECCCCEEEEEHHHHHHCCCCCCCCCHHEEECCCCCCCCCEEECC
EARDGDTVVVMGVGGLGINAVQGARLAGARYVVALDPVAYKRERSFEFGATHAAATVEEA
CCCCCCEEEEEEECCCCCCCCCCCEECCCEEEEEECCHHHHHCCCCCCCCCHHHHHHHHH
QALITDLTRGTMADVCVVTTDSAEGAYVAQGLSLVGKRGRVVMTAIPHPTDTTVDMSLFD
HHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEHHH
LTLYEKQVRGCLFGSSNPRLDIPRMLELFGSGRLMLDELITREYTLDEINQGYEDMHDGR
HHHHHHHHCEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCHHHHHCCHHHHHCCC
NLRGLIRF
CCEEEECC
>Mature Secondary Structure
MKTKAAVLWGLHQKWEVTELDLDAPKAQEVLVKLTASGLCHSDDHLVTGDMPMNLPVVGG
CCCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEECC
HEGAGVVAEVGPGVTEVEVGDHVVLSFIPACGRCTECARGRSNLCVYGAAIVAGPQLDGT
CCCCCEEEECCCCCEEEECCCEEEEHHHCCCCCHHHHHCCCCCEEEEEEEEEECCCCCCE
YRFHSGGQDVGQMCVLGTFSEYTVVPIASVVKVDKDIPLDKAALVGCGVTTGYGAAVRTG
EEECCCCCCHHCEEEEECCCCEEEEEHHHHHHCCCCCCCCCHHEEECCCCCCCCCEEECC
EARDGDTVVVMGVGGLGINAVQGARLAGARYVVALDPVAYKRERSFEFGATHAAATVEEA
CCCCCCEEEEEEECCCCCCCCCCCEECCCEEEEEECCHHHHHCCCCCCCCCHHHHHHHHH
QALITDLTRGTMADVCVVTTDSAEGAYVAQGLSLVGKRGRVVMTAIPHPTDTTVDMSLFD
HHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEHHH
LTLYEKQVRGCLFGSSNPRLDIPRMLELFGSGRLMLDELITREYTLDEINQGYEDMHDGR
HHHHHHHHCEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCHHHHHCCHHHHHCCC
NLRGLIRF
CCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]