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The map label for this gene is yfnA [H]

Identifier: 108801531

GI number: 108801531

Start: 4844805

End: 4846217

Strand: Reverse

Name: yfnA [H]

Synonym: Mmcs_4568

Alternate gene names: 108801531

Gene position: 4846217-4844805 (Counterclockwise)

Preceding gene: 108801532

Following gene: 108801529

Centisome position: 84.94

GC content: 66.03

Gene sequence:

>1413_bases
ATGACCCACCCAGACACGGTCAGGGAGCAGCCCGAGCTACGGCGGGTGATGGGCCCCGGGCTGTTGCTGCTGTTCGTCGT
CGGCGACATCCTCGGCACCGGTGTGTACGCGCTGACCGGTGACGTGGCCGCCGAAGTCGGTGGTGCAGCGTGGCTTCCGT
TCCTGGTCGCCTTCCTCATCGCCACCATCACCGCCTTCAGCTATCTGGAGCTGGTCACCAAGTACCCGCAGGCGGCCGGG
GCTGCGCTCTACGCGCACAAGGCTTTCGGCCTTCAGTTCGTCACGTTCCTGGTGGCTTTCGTGGTGATGTGCTCGGGCAT
CACGTCGGCCTCGACCGCGTCACGGTTCTTCGGCGCCAACCTCATCGAGGGGTTCGGGCTGGAGTGGGGCACAGCCGGTG
TGGCGGCCGTCGCGCTGGGGTTCATGGCGCTTCTGGCGGCCGTGAACTTCCGCGGCGTGGGCGAGAGCATCAAACTCAAC
GTGGTCCTCACCATCATCGAGGCGACCGGCCTCATGCTGGTGCTCTTCGTGGGCCTGTGGGCGTTCACCCGCGGCGGCGA
CGTCGACTTCTCCCGCGTCGTCGCCTTCGACACCGCCGGCGACAAGAACGCTTTCATGGCCGTCACCGCCGCGACGTCGT
TGGCGTTCTTCGCGATGGTCGGCTTCGAGGACTCGGTCAACATGGCCGAGGAGACCAAGGATCCCGTCAAGACCTTCCCG
AAGGTGCTGCTGTCCGGGCTCACCATCGCCGGCATCGTCTACATGCTCGTCGCCGTCGTCGCGGTGGCCCTGGTGCCCGT
CGGCCGGCTCGAGGAGAGCGACACCCCGCTGGTCGAGGTGGTCAAGGCCGGGGCGCCGAACCTGCCGATCGACACGCTTT
TCCCGTTCATCTCGATGTTCGCGGTCTCCAACACCGCACTCATCAACATGCTGATGGCCAGTCGACTGATCTACGGAATG
GCCCGGCAGCATGTGCTGCCGCCGGTTTTCGGCACCGTCCACCCCCGGCGGCTGACCCCCTGGGTGGCGATCGTGTTCAC
CACGCTGATCGCGTTCGGCCTGATCTTCTACGTCAGTGTGTTCGCCAGCAGCAGCGCCATCAGTGTGCTCGGCGGCACCA
CGTCGCTGTTGCTGCTGGCAGTGTTCGCCGTGGTCAACGTCGCGGTGCTGCGGCTACGACGTGACGTGCAGGCCGGCGGT
GCGCACTTCAAGACGCCGACGGTGATGCCGGTGGTCGGCTTCATCGCGTCGTTGTATCTGGTGCTGCCGTTCTCCGGTCG
CCCCGCCCAGCAGTACTACGTGGCGCTGATCCTCGTCGCGATCGGGATCGTGCTGTTCTTCATCAACAGGCTGATCAACC
GGCGCCTGGGTGTGCGCGACACCGAGATCACCGACCCCACGCACCTGGCGTAG

Upstream 100 bases:

>100_bases
GTGGGCTGAGCGCAGGTCCGGCAACGATTGCGGCAATGATGCTGCGTCGAGGTCGCCGCTGCCCGATGATGATGACCTGG
CAACAGTGACGGAGGAGCGC

Downstream 100 bases:

>100_bases
CGGCCCGACGGAGTGCGGGCGTCACGATCCGGCCGGTGGCGTCGTCGCCGTAGCTCGTGACGTCGGCAGGCCTGCGGGTG
GCGAACAGCGCGACGTAGGC

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MTHPDTVREQPELRRVMGPGLLLLFVVGDILGTGVYALTGDVAAEVGGAAWLPFLVAFLIATITAFSYLELVTKYPQAAG
AALYAHKAFGLQFVTFLVAFVVMCSGITSASTASRFFGANLIEGFGLEWGTAGVAAVALGFMALLAAVNFRGVGESIKLN
VVLTIIEATGLMLVLFVGLWAFTRGGDVDFSRVVAFDTAGDKNAFMAVTAATSLAFFAMVGFEDSVNMAEETKDPVKTFP
KVLLSGLTIAGIVYMLVAVVAVALVPVGRLEESDTPLVEVVKAGAPNLPIDTLFPFISMFAVSNTALINMLMASRLIYGM
ARQHVLPPVFGTVHPRRLTPWVAIVFTTLIAFGLIFYVSVFASSSAISVLGGTTSLLLLAVFAVVNVAVLRLRRDVQAGG
AHFKTPTVMPVVGFIASLYLVLPFSGRPAQQYYVALILVAIGIVLFFINRLINRRLGVRDTEITDPTHLA

Sequences:

>Translated_470_residues
MTHPDTVREQPELRRVMGPGLLLLFVVGDILGTGVYALTGDVAAEVGGAAWLPFLVAFLIATITAFSYLELVTKYPQAAG
AALYAHKAFGLQFVTFLVAFVVMCSGITSASTASRFFGANLIEGFGLEWGTAGVAAVALGFMALLAAVNFRGVGESIKLN
VVLTIIEATGLMLVLFVGLWAFTRGGDVDFSRVVAFDTAGDKNAFMAVTAATSLAFFAMVGFEDSVNMAEETKDPVKTFP
KVLLSGLTIAGIVYMLVAVVAVALVPVGRLEESDTPLVEVVKAGAPNLPIDTLFPFISMFAVSNTALINMLMASRLIYGM
ARQHVLPPVFGTVHPRRLTPWVAIVFTTLIAFGLIFYVSVFASSSAISVLGGTTSLLLLAVFAVVNVAVLRLRRDVQAGG
AHFKTPTVMPVVGFIASLYLVLPFSGRPAQQYYVALILVAIGIVLFFINRLINRRLGVRDTEITDPTHLA
>Mature_469_residues
THPDTVREQPELRRVMGPGLLLLFVVGDILGTGVYALTGDVAAEVGGAAWLPFLVAFLIATITAFSYLELVTKYPQAAGA
ALYAHKAFGLQFVTFLVAFVVMCSGITSASTASRFFGANLIEGFGLEWGTAGVAAVALGFMALLAAVNFRGVGESIKLNV
VLTIIEATGLMLVLFVGLWAFTRGGDVDFSRVVAFDTAGDKNAFMAVTAATSLAFFAMVGFEDSVNMAEETKDPVKTFPK
VLLSGLTIAGIVYMLVAVVAVALVPVGRLEESDTPLVEVVKAGAPNLPIDTLFPFISMFAVSNTALINMLMASRLIYGMA
RQHVLPPVFGTVHPRRLTPWVAIVFTTLIAFGLIFYVSVFASSSAISVLGGTTSLLLLAVFAVVNVAVLRLRRDVQAGGA
HFKTPTVMPVVGFIASLYLVLPFSGRPAQQYYVALILVAIGIVLFFINRLINRRLGVRDTEITDPTHLA

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=384, Percent_Identity=26.0416666666667, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI110347453, Length=366, Percent_Identity=27.0491803278689, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI187423910, Length=462, Percent_Identity=21.6450216450216, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI7657591, Length=462, Percent_Identity=21.6450216450216, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87081869, Length=372, Percent_Identity=23.9247311827957, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790584, Length=319, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789017, Length=442, Percent_Identity=25.1131221719457, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87082250, Length=441, Percent_Identity=25.6235827664399, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786694, Length=402, Percent_Identity=23.6318407960199, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=409, Percent_Identity=22.9828850855746, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17533459, Length=366, Percent_Identity=24.3169398907104, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32566699, Length=309, Percent_Identity=25.2427184466019, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71995388, Length=361, Percent_Identity=21.8836565096953, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71995382, Length=361, Percent_Identity=21.8836565096953, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24667468, Length=368, Percent_Identity=24.7282608695652, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24666159, Length=423, Percent_Identity=23.4042553191489, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221512776, Length=423, Percent_Identity=23.4042553191489, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24668806, Length=411, Percent_Identity=24.0875912408759, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356285, Length=411, Percent_Identity=24.0875912408759, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24668802, Length=411, Percent_Identity=24.0875912408759, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50025; Mature: 49894

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPDTVREQPELRRVMGPGLLLLFVVGDILGTGVYALTGDVAAEVGGAAWLPFLVAFLI
CCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHH
ATITAFSYLELVTKYPQAAGAALYAHKAFGLQFVTFLVAFVVMCSGITSASTASRFFGAN
HHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCH
LIEGFGLEWGTAGVAAVALGFMALLAAVNFRGVGESIKLNVVLTIIEATGLMLVLFVGLW
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHH
AFTRGGDVDFSRVVAFDTAGDKNAFMAVTAATSLAFFAMVGFEDSVNMAEETKDPVKTFP
HHCCCCCCCHHHEEEEECCCCCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHH
KVLLSGLTIAGIVYMLVAVVAVALVPVGRLEESDTPLVEVVKAGAPNLPIDTLFPFISMF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHH
AVSNTALINMLMASRLIYGMARQHVLPPVFGTVHPRRLTPWVAIVFTTLIAFGLIFYVSV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FASSSAISVLGGTTSLLLLAVFAVVNVAVLRLRRDVQAGGAHFKTPTVMPVVGFIASLYL
HHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
VLPFSGRPAQQYYVALILVAIGIVLFFINRLINRRLGVRDTEITDPTHLA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
THPDTVREQPELRRVMGPGLLLLFVVGDILGTGVYALTGDVAAEVGGAAWLPFLVAFLI
CCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHH
ATITAFSYLELVTKYPQAAGAALYAHKAFGLQFVTFLVAFVVMCSGITSASTASRFFGAN
HHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCH
LIEGFGLEWGTAGVAAVALGFMALLAAVNFRGVGESIKLNVVLTIIEATGLMLVLFVGLW
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHH
AFTRGGDVDFSRVVAFDTAGDKNAFMAVTAATSLAFFAMVGFEDSVNMAEETKDPVKTFP
HHCCCCCCCHHHEEEEECCCCCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHH
KVLLSGLTIAGIVYMLVAVVAVALVPVGRLEESDTPLVEVVKAGAPNLPIDTLFPFISMF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHH
AVSNTALINMLMASRLIYGMARQHVLPPVFGTVHPRRLTPWVAIVFTTLIAFGLIFYVSV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FASSSAISVLGGTTSLLLLAVFAVVNVAVLRLRRDVQAGGAHFKTPTVMPVVGFIASLYL
HHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
VLPFSGRPAQQYYVALILVAIGIVLFFINRLINRRLGVRDTEITDPTHLA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]