Click here to switch to the map view.

The map label for this gene is ptrB [H]

Identifier: 108801522

GI number: 108801522

Start: 4832705

End: 4834825

Strand: Reverse

Name: ptrB [H]

Synonym: Mmcs_4559

Alternate gene names: 108801522

Gene position: 4834825-4832705 (Counterclockwise)

Preceding gene: 108801523

Following gene: 108801521

Centisome position: 84.74

GC content: 67.52

Gene sequence:

>2121_bases
ATGACCGTCCCGCCGCCGCAGGCCAAACGGGTTGAACAGCGGCGCGAACACCACGGCGACGTGTTCATCGACCCCTACGA
GTGGCTGCGCGACAAATCCGATCCCGAGGTGCTTGCCCACCTGGAGGCCGAGAACGCCTACACCGAGGCGCAGACCGCGC
ATCTCGCGCCGTTGCGGCAGAAGATCTTCGACGAGATCAAGGCCCGCACCAAGGAGACCGACCTCTCGGTGCCCACCCGG
CGCGGCAACTGGTGGTACTACGGGCGCAGCTTCGAGGGTAAGCAGTACGGCGTCCACTGCCGTTGCCCTGTCGCAGATCC
CGAGGACTGGACACCTCCGGTGCTCGACGAGAACACCACCATCGACGGTGAACAGGTCCTGCTCGACGAGAACGTCGAAG
CCGAGGGCCACGAGTTCTTCGCGCTCGGGGCGGCCACCGTCAGCATCGACGGCAACGTCCTGGCCTACTCCGTCGACACA
GTGGGCGACGAGCGGTACACACTGCGGTTCAAAGACCTCCGCACCGGCGAGCAGTACGACGACACGATCGTCGGGATCGG
TGCCGGCGCCACCTGGGCCGCCGACAACCGCACCATCTACTACAGCACCGTCGACGACGCCTGGCGGCCCGACACCGTGT
GGCGCCACCGGTTGGGGGCGGGGTTGCCGGCCGAACGGGTGTACCACGAACCCGACGAACGGTACTGGCTGGGCGTCGGC
CGCACCCGCAGCGACAAGTACCTGATCATCGCCGCGGGCAGCGCCGTCACCTCGGAGGTGCGCTACGCCGACGCGAGTGA
TCCGGAGGCGGAGTTCGCCGTGGTGTGGCCGCGCCGCGACGGGGTCGAGTACTCCGTCGAACACGCGGTGGTCGGCGGGG
AGGACCGGTTCCTCATCATGCACAACGACGGTGCGGAGAACTTCGCACTCGTCGACGCGCCGGTGGCCGATCCGGGCGCG
GCCCGCACGCTCATCGAACACCGCGAGGACGTGCGACTCGACGCGGTCGACGCGTTCGCCGGACACCTCGTGCTGAGTTA
CCGCGAAGAGGCACTGCCCAAGATCCAACTGTGGCCCCTGGGCGCCGACGGATCATACGGTCGCGCCGAGGACATCACCT
TCGACACCGAACTGACCTCGGCGGGGCTGGGCGGCAACCCGAACTGGGACGCGCCGAAAATGCGCATCGCGGCAACGTCT
TTCGTCACCCCGGTGCGGATCTACGACCTCGACCTCGCAACAGGGGAGCGCACGCTGCTGCGCGAGCAGCCGGTGCTCGG
CGGCTACCGGCCCGAGGACTACGTCGAGCGCAGGGACTGGGCGATCGCCCCGGACGGCGCGCGGGTGCCCATCTCGATCG
TCCACCGTGCCGGCCTTCAGTTTCCGGCACCGACCCTGCTCTACGGCTACGGCGCCTACGAGTCGTGTGAGGACCCACGG
TTCTCGATCGCCCGGCTCTCCCTGCTGGACCGCGGCATGGTGTTCGCCGTCGCCCACGTCCGCGGCGGCGGGGAACTCGG
CCGGCCGTGGTACGAACAGGGCAAGATGCTGGAGAAGGGCAACACCTTCACCGACTTCATCGCGGTGGCAAGGCATCTCA
TCGCCACCGACACCACGCGGCCGCAGAACCTGGTGGCGCTCGGCGGCAGCGCCGGTGGGTTGTTGATCGGTGCGGTCGCC
AACCTGGCGCCCGAACTGTTCGCCGGCTTCCTGGCACAGGTGCCGTTCGTCGATCCGTTGACCACTATCCTCGACCCGTC
GCTGCCGCTGACGGTCACCGAGTGGGACGAATGGGGCAACCCGCTCGAGCACGAGCACGTCTACCACTACATGAAGTCCT
ACTCGCCGTACGAGAACGTCGTCGCCAAGGACTATCCGCCGATCCTGGCGATGACCTCGCTCAACGACACCCGTGTGTAC
TACGTCGAACCGGCGAAATGGATTGCCGCCCTTCGGCACACGAAGACCGACGGGAACCCGGTGCTGCTCAAGACCGAGAT
GAGCGCCGGACACGGCGGGATCAGCGGACGCTACGAACGGTGGAAGGAAGCCGCGTTCCAGTACGCCTGGGTGCTCGCGA
CCGCCGACCCGGAGACCTACGACAACCGAAGCCCGAACTAG

Upstream 100 bases:

>100_bases
CGCTTCCCGCCGAGATCGTCGACGCCACCCGTTCGCGTTACATCGAAGCCTACGAACGCATTTCGGGTCTGAGCTTCGCC
GAGTGGATCGGCGCGAGCGC

Downstream 100 bases:

>100_bases
TCACTGTCAAGACCGCGGATAGGATGTTCGGGTGGCCAAGTCGAGCTACCACCACGGCGACCTGAAATCGGCGATCCTGG
CGCAGGCCGCCGAACTGGTC

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 706; Mature: 705

Protein sequence:

>706_residues
MTVPPPQAKRVEQRREHHGDVFIDPYEWLRDKSDPEVLAHLEAENAYTEAQTAHLAPLRQKIFDEIKARTKETDLSVPTR
RGNWWYYGRSFEGKQYGVHCRCPVADPEDWTPPVLDENTTIDGEQVLLDENVEAEGHEFFALGAATVSIDGNVLAYSVDT
VGDERYTLRFKDLRTGEQYDDTIVGIGAGATWAADNRTIYYSTVDDAWRPDTVWRHRLGAGLPAERVYHEPDERYWLGVG
RTRSDKYLIIAAGSAVTSEVRYADASDPEAEFAVVWPRRDGVEYSVEHAVVGGEDRFLIMHNDGAENFALVDAPVADPGA
ARTLIEHREDVRLDAVDAFAGHLVLSYREEALPKIQLWPLGADGSYGRAEDITFDTELTSAGLGGNPNWDAPKMRIAATS
FVTPVRIYDLDLATGERTLLREQPVLGGYRPEDYVERRDWAIAPDGARVPISIVHRAGLQFPAPTLLYGYGAYESCEDPR
FSIARLSLLDRGMVFAVAHVRGGGELGRPWYEQGKMLEKGNTFTDFIAVARHLIATDTTRPQNLVALGGSAGGLLIGAVA
NLAPELFAGFLAQVPFVDPLTTILDPSLPLTVTEWDEWGNPLEHEHVYHYMKSYSPYENVVAKDYPPILAMTSLNDTRVY
YVEPAKWIAALRHTKTDGNPVLLKTEMSAGHGGISGRYERWKEAAFQYAWVLATADPETYDNRSPN

Sequences:

>Translated_706_residues
MTVPPPQAKRVEQRREHHGDVFIDPYEWLRDKSDPEVLAHLEAENAYTEAQTAHLAPLRQKIFDEIKARTKETDLSVPTR
RGNWWYYGRSFEGKQYGVHCRCPVADPEDWTPPVLDENTTIDGEQVLLDENVEAEGHEFFALGAATVSIDGNVLAYSVDT
VGDERYTLRFKDLRTGEQYDDTIVGIGAGATWAADNRTIYYSTVDDAWRPDTVWRHRLGAGLPAERVYHEPDERYWLGVG
RTRSDKYLIIAAGSAVTSEVRYADASDPEAEFAVVWPRRDGVEYSVEHAVVGGEDRFLIMHNDGAENFALVDAPVADPGA
ARTLIEHREDVRLDAVDAFAGHLVLSYREEALPKIQLWPLGADGSYGRAEDITFDTELTSAGLGGNPNWDAPKMRIAATS
FVTPVRIYDLDLATGERTLLREQPVLGGYRPEDYVERRDWAIAPDGARVPISIVHRAGLQFPAPTLLYGYGAYESCEDPR
FSIARLSLLDRGMVFAVAHVRGGGELGRPWYEQGKMLEKGNTFTDFIAVARHLIATDTTRPQNLVALGGSAGGLLIGAVA
NLAPELFAGFLAQVPFVDPLTTILDPSLPLTVTEWDEWGNPLEHEHVYHYMKSYSPYENVVAKDYPPILAMTSLNDTRVY
YVEPAKWIAALRHTKTDGNPVLLKTEMSAGHGGISGRYERWKEAAFQYAWVLATADPETYDNRSPN
>Mature_705_residues
TVPPPQAKRVEQRREHHGDVFIDPYEWLRDKSDPEVLAHLEAENAYTEAQTAHLAPLRQKIFDEIKARTKETDLSVPTRR
GNWWYYGRSFEGKQYGVHCRCPVADPEDWTPPVLDENTTIDGEQVLLDENVEAEGHEFFALGAATVSIDGNVLAYSVDTV
GDERYTLRFKDLRTGEQYDDTIVGIGAGATWAADNRTIYYSTVDDAWRPDTVWRHRLGAGLPAERVYHEPDERYWLGVGR
TRSDKYLIIAAGSAVTSEVRYADASDPEAEFAVVWPRRDGVEYSVEHAVVGGEDRFLIMHNDGAENFALVDAPVADPGAA
RTLIEHREDVRLDAVDAFAGHLVLSYREEALPKIQLWPLGADGSYGRAEDITFDTELTSAGLGGNPNWDAPKMRIAATSF
VTPVRIYDLDLATGERTLLREQPVLGGYRPEDYVERRDWAIAPDGARVPISIVHRAGLQFPAPTLLYGYGAYESCEDPRF
SIARLSLLDRGMVFAVAHVRGGGELGRPWYEQGKMLEKGNTFTDFIAVARHLIATDTTRPQNLVALGGSAGGLLIGAVAN
LAPELFAGFLAQVPFVDPLTTILDPSLPLTVTEWDEWGNPLEHEHVYHYMKSYSPYENVVAKDYPPILAMTSLNDTRVYY
VEPAKWIAALRHTKTDGNPVLLKTEMSAGHGGISGRYERWKEAAFQYAWVLATADPETYDNRSPN

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=716, Percent_Identity=25.4189944134078, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI284172420, Length=471, Percent_Identity=29.9363057324841, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI284172413, Length=471, Percent_Identity=29.9363057324841, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI70778815, Length=471, Percent_Identity=29.9363057324841, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI284172438, Length=460, Percent_Identity=30, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI284172431, Length=460, Percent_Identity=30, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI108860686, Length=276, Percent_Identity=34.4202898550725, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI108860692, Length=209, Percent_Identity=38.2775119617225, Blast_Score=123, Evalue=5e-28,
Organism=Escherichia coli, GI1788150, Length=696, Percent_Identity=38.3620689655172, Blast_Score=453, Evalue=1e-128,
Organism=Drosophila melanogaster, GI24583414, Length=723, Percent_Identity=27.939142461964, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI221510989, Length=724, Percent_Identity=25.828729281768, Blast_Score=175, Evalue=8e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 78785; Mature: 78653

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVPPPQAKRVEQRREHHGDVFIDPYEWLRDKSDPEVLAHLEAENAYTEAQTAHLAPLRQ
CCCCCCHHHHHHHHHHHCCCEEECHHHHHCCCCCCHHEEEEECCCCHHHHHHHHHHHHHH
KIFDEIKARTKETDLSVPTRRGNWWYYGRSFEGKQYGVHCRCPVADPEDWTPPVLDENTT
HHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCC
IDGEQVLLDENVEAEGHEFFALGAATVSIDGNVLAYSVDTVGDERYTLRFKDLRTGEQYD
CCCCEEEEECCCCCCCCEEEEEEEEEEEECCCEEEEEEECCCCCEEEEEEEECCCCCCCC
DTIVGIGAGATWAADNRTIYYSTVDDAWRPDTVWRHRLGAGLPAERVYHEPDERYWLGVG
CEEEEECCCCEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCCHHHHCCCCCCCEEEECC
RTRSDKYLIIAAGSAVTSEVRYADASDPEAEFAVVWPRRDGVEYSVEHAVVGGEDRFLIM
CCCCCCEEEEECCCHHCCCEEECCCCCCCCCEEEEECCCCCCCEEEEEEEECCCCEEEEE
HNDGAENFALVDAPVADPGAARTLIEHREDVRLDAVDAFAGHLVLSYREEALPKIQLWPL
ECCCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEHHHHHHHHHEEEEHHHCCCEEEEEEE
GADGSYGRAEDITFDTELTSAGLGGNPNWDAPKMRIAATSFVTPVRIYDLDLATGERTLL
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEHHCCCEEEEEEEECCCCCHHHH
REQPVLGGYRPEDYVERRDWAIAPDGARVPISIVHRAGLQFPAPTLLYGYGAYESCEDPR
HCCCCCCCCCCHHHHHCCCCEECCCCCCCCHHHHHHCCCCCCCCCEEEECCCCCCCCCCC
FSIARLSLLDRGMVFAVAHVRGGGELGRPWYEQGKMLEKGNTFTDFIAVARHLIATDTTR
HHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHCCCEECCCCCHHHHHHHHHHHHHCCCCC
PQNLVALGGSAGGLLIGAVANLAPELFAGFLAQVPFVDPLTTILDPSLPLTVTEWDEWGN
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEECHHHCCC
PLEHEHVYHYMKSYSPYENVVAKDYPPILAMTSLNDTRVYYVEPAKWIAALRHTKTDGNP
CCCHHHHHHHHHCCCCHHHHHHCCCCCEEEEECCCCCEEEEECHHHHHHHHHHCCCCCCE
VLLKTEMSAGHGGISGRYERWKEAAFQYAWVLATADPETYDNRSPN
EEEEEECCCCCCCCCCHHHHHHHHHHEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
TVPPPQAKRVEQRREHHGDVFIDPYEWLRDKSDPEVLAHLEAENAYTEAQTAHLAPLRQ
CCCCCHHHHHHHHHHHCCCEEECHHHHHCCCCCCHHEEEEECCCCHHHHHHHHHHHHHH
KIFDEIKARTKETDLSVPTRRGNWWYYGRSFEGKQYGVHCRCPVADPEDWTPPVLDENTT
HHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCC
IDGEQVLLDENVEAEGHEFFALGAATVSIDGNVLAYSVDTVGDERYTLRFKDLRTGEQYD
CCCCEEEEECCCCCCCCEEEEEEEEEEEECCCEEEEEEECCCCCEEEEEEEECCCCCCCC
DTIVGIGAGATWAADNRTIYYSTVDDAWRPDTVWRHRLGAGLPAERVYHEPDERYWLGVG
CEEEEECCCCEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCCHHHHCCCCCCCEEEECC
RTRSDKYLIIAAGSAVTSEVRYADASDPEAEFAVVWPRRDGVEYSVEHAVVGGEDRFLIM
CCCCCCEEEEECCCHHCCCEEECCCCCCCCCEEEEECCCCCCCEEEEEEEECCCCEEEEE
HNDGAENFALVDAPVADPGAARTLIEHREDVRLDAVDAFAGHLVLSYREEALPKIQLWPL
ECCCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEHHHHHHHHHEEEEHHHCCCEEEEEEE
GADGSYGRAEDITFDTELTSAGLGGNPNWDAPKMRIAATSFVTPVRIYDLDLATGERTLL
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEHHCCCEEEEEEEECCCCCHHHH
REQPVLGGYRPEDYVERRDWAIAPDGARVPISIVHRAGLQFPAPTLLYGYGAYESCEDPR
HCCCCCCCCCCHHHHHCCCCEECCCCCCCCHHHHHHCCCCCCCCCEEEECCCCCCCCCCC
FSIARLSLLDRGMVFAVAHVRGGGELGRPWYEQGKMLEKGNTFTDFIAVARHLIATDTTR
HHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHCCCEECCCCCHHHHHHHHHHHHHCCCCC
PQNLVALGGSAGGLLIGAVANLAPELFAGFLAQVPFVDPLTTILDPSLPLTVTEWDEWGN
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEECHHHCCC
PLEHEHVYHYMKSYSPYENVVAKDYPPILAMTSLNDTRVYYVEPAKWIAALRHTKTDGNP
CCCHHHHHHHHHCCCCHHHHHHCCCCCEEEEECCCCCEEEEECHHHHHHHHHHCCCCCCE
VLLKTEMSAGHGGISGRYERWKEAAFQYAWVLATADPETYDNRSPN
EEEEEECCCCCCCCCCHHHHHHHHHHEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7629037 [H]