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The map label for this gene is purQ [H]

Identifier: 108801515

GI number: 108801515

Start: 4828509

End: 4829183

Strand: Reverse

Name: purQ [H]

Synonym: Mmcs_4552

Alternate gene names: 108801515

Gene position: 4829183-4828509 (Counterclockwise)

Preceding gene: 108801516

Following gene: 108801514

Centisome position: 84.64

GC content: 69.33

Gene sequence:

>675_bases
ATGAGCGCCCGGGTGGGAGTGATCACCTTCCCCGGAACCCTCGACGACGTCGACGCGGCCCGCGCGGTGCGCCTCGCCGG
TGGTGAGCCGGTCAGCCTGTGGCACGCCGACGCCGACCTCAAGAAGGTCGACGCCGTCATCGTGCCCGGCGGATTCTCCT
ACGGCGACTACCTGCGTGCGGGGGCGATCGCCAAGTTCGCACCGGTCATGGGTGAGGTCGTGCGCGCCGCCGAGGGCGGT
ATGCCGGTGCTCGGCATCTGCAACGGCTTTCAGGTGCTGTGCGAAGCCGGCCTGCTGCCCGGGGCGCTGACCCGCAACAT
CGGTCTGCACTTCATCTGCCGCGACACCTGGCTGCAGGTCGCCTCCAACACCTCGGCATGGACCACCCGCTACGAGAACG
GCGCCGATCTGCTCATCCCGCTGAAGTCGGGGGAGGGCCGTTACGTCGCCAGCGAGAAAGTCCTCGACGAGCTCGAGGGC
GAGGGCCGGGTGGTGTTCCGCTACCGCGAGAACCTCAACGGATCGATGCGCGACATCGCCGGCATCAGCTCGGCGAACGG
GCGCGTCGTCGGCCTCATGCCGCACCCCGAACACGCCACCGAGGCGCTCACCGGCCCCTCCGATGACGGCCTGGGGTTGT
TCTACTCGGCGCTCGACGCGGTGCTGACCGTCTAG

Upstream 100 bases:

>100_bases
AGTTCGACGGCGACGTCACGGACGAGACGGTGGCCGAGATCGCCGAATCGCTCCTGGCGAACACCGTCATCGAGGACTGG
TCGGTCAGTAGAGAGGGCGC

Downstream 100 bases:

>100_bases
GTTCGGTCGCCACTACCTCGTATCAGGCTGCGCCGCTGCGCTATTGACCCCTCAAGCGTGCGTTCCGGCTCTGAAACGCG
CCTGAAACGTCTTTGCCACC

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MSARVGVITFPGTLDDVDAARAVRLAGGEPVSLWHADADLKKVDAVIVPGGFSYGDYLRAGAIAKFAPVMGEVVRAAEGG
MPVLGICNGFQVLCEAGLLPGALTRNIGLHFICRDTWLQVASNTSAWTTRYENGADLLIPLKSGEGRYVASEKVLDELEG
EGRVVFRYRENLNGSMRDIAGISSANGRVVGLMPHPEHATEALTGPSDDGLGLFYSALDAVLTV

Sequences:

>Translated_224_residues
MSARVGVITFPGTLDDVDAARAVRLAGGEPVSLWHADADLKKVDAVIVPGGFSYGDYLRAGAIAKFAPVMGEVVRAAEGG
MPVLGICNGFQVLCEAGLLPGALTRNIGLHFICRDTWLQVASNTSAWTTRYENGADLLIPLKSGEGRYVASEKVLDELEG
EGRVVFRYRENLNGSMRDIAGISSANGRVVGLMPHPEHATEALTGPSDDGLGLFYSALDAVLTV
>Mature_223_residues
SARVGVITFPGTLDDVDAARAVRLAGGEPVSLWHADADLKKVDAVIVPGGFSYGDYLRAGAIAKFAPVMGEVVRAAEGGM
PVLGICNGFQVLCEAGLLPGALTRNIGLHFICRDTWLQVASNTSAWTTRYENGADLLIPLKSGEGRYVASEKVLDELEGE
GRVVFRYRENLNGSMRDIAGISSANGRVVGLMPHPEHATEALTGPSDDGLGLFYSALDAVLTV

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=223, Percent_Identity=30.0448430493274, Blast_Score=67, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321498, Length=179, Percent_Identity=32.4022346368715, Blast_Score=72, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24582111, Length=205, Percent_Identity=30.7317073170732, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24582109, Length=205, Percent_Identity=30.7317073170732, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17137292, Length=205, Percent_Identity=30.7317073170732, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR010075 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 23660; Mature: 23529

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARVGVITFPGTLDDVDAARAVRLAGGEPVSLWHADADLKKVDAVIVPGGFSYGDYLRA
CCCCEEEEECCCCCCCCCHHHEEEECCCCEEEEEECCCCHHHEEEEEECCCCCHHHHHHH
GAIAKFAPVMGEVVRAAEGGMPVLGICNGFQVLCEAGLLPGALTRNIGLHFICRDTWLQV
CHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHCCCCCCHHHHCCCEEEEEEHHHHHH
ASNTSAWTTRYENGADLLIPLKSGEGRYVASEKVLDELEGEGRVVFRYRENLNGSMRDIA
HCCCCCEEEEECCCCEEEEEEECCCCCEEEHHHHHHHHCCCCEEEEEEECCCCCCHHHHC
GISSANGRVVGLMPHPEHATEALTGPSDDGLGLFYSALDAVLTV
CCCCCCCEEEEECCCCCHHHHHCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SARVGVITFPGTLDDVDAARAVRLAGGEPVSLWHADADLKKVDAVIVPGGFSYGDYLRA
CCCEEEEECCCCCCCCCHHHEEEECCCCEEEEEECCCCHHHEEEEEECCCCCHHHHHHH
GAIAKFAPVMGEVVRAAEGGMPVLGICNGFQVLCEAGLLPGALTRNIGLHFICRDTWLQV
CHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHCCCCCCHHHHCCCEEEEEEHHHHHH
ASNTSAWTTRYENGADLLIPLKSGEGRYVASEKVLDELEGEGRVVFRYRENLNGSMRDIA
HCCCCCEEEEECCCCEEEEEEECCCCCEEEHHHHHHHHCCCCEEEEEEECCCCCCHHHHC
GISSANGRVVGLMPHPEHATEALTGPSDDGLGLFYSALDAVLTV
CCCCCCCEEEEECCCCCHHHHHCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]